® The LICOX System Brain Tissue Oxygen Monitoring System Product Presentation NS1581-09/07 What is the LICOX® system? • Measures interstitial brain tissue oxygenation (P O ) in bt 2 mmHg and brain temperature (°C) • Probe inserted approximately 35mm below the dura into the white matter of the brain • P O used in conjunction bt 2 with current ICP/CPP monitoring methods 11/2/2007 2 Who needs the LICOX® system? (cid:1) Patients at risk for developing cerebral hypoxia or ischemia (cid:1) Head trauma patients (cid:1) Aneurysm patients (cid:1) Subarachnoid hemorrhage patients (cid:1) Stroke patients © 2007 Dr. Marcos Tatagiba. Reprinted with permission. 11/2/2007 3 When is the LICOX® system placed? • Within the first 24-48 hours of injury – The sooner cerebral hypoxia is detected, the better secondary injury can be prevented • Generally, when an ICP catheter is required, a LICOX® probe should be considered 11/2/2007 4 How is the LICOX® system placed? • Can be either bolted or tunneled • Can be placed independently or with an ICP catheter • Requires minimal additional effort • Does not need to be zeroed prior to placement, SMART card is included with each O probe 2 with all calibration data • Monitor need not be present when placing in the OR 11/2/2007 5 Where is the LICOX® system placed? • Placement is up to • LICOX® probe can be clinical discretion placed in either the injured side or non-injured side of • The idea is to prevent brain SECONDARY injury by ensuring living • Should not be placed tissue is receiving directly into a lesion adequate oxygen 11/2/2007 6 What are the probe options? • BOLTED (cid:1) Double Lumen – Camino® ICP channel and LICOX® PMO catheter channel (IP2P) • TUNNELED (cid:1) Licox® PMO combined oxygen and temperature catheter (IT2) • Probe kits come with required drill bits and other accessories 11/2/2007 7 How accurate are the probes? Oxygen Accuracy: (cid:1) P O 0-20 mmHg accuracy is ± 2 mmHg bt 2 (cid:1) P O 21-50 mmHg accuracy is ± 10% bt 2 (cid:1) P O 51-150 mmHg accuracy is ± 13% bt 2 Temperature Accuracy: ± 0.2 °C 11/2/2007 8 What about the nursing staff? • Simple monitor set-up and use • The monitor displays a digital oxygen and temperature reading • Alarms are managed through a connection to the bedside monitor 11/2/2007 9 What is a “normal” reading? • Normal: 25-35 mmHg • Risk of death increases – < 15 mmHg for 30 minutes – < 10 mmHg for 10 minutes • P O < 5 mmHg bt 2 – high mortality • P O < 2mmHg - neuronal death1 bt 2 1- Bardt T, Unterberg A, et al. Monitoring of brain tissue PO2 in traumatic brain injury: effect of cerebral hypoxia on outcome. Acta Neurochirurgica.1998;71(Suppl):153-156. 11/2/2007 10
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