Review of Pharmacology

1745 Pages·2020·71.303 MB·English

by  Dr. Gobind Rai Garg, Dr. Sparsh Gupta

Jaypee Brothers Medical Publishers (P) Ltd

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© 2020, Gobind Rai Garg and Sparsh Gupta
The views and opinions expressed in this book are solely those of the original
contributor(s)/author(s) and do not necessarily represent those of editor(s) of
the book.
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of the publishers.
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owners. The publisher is not associated with any product or vendor
mentioned in this book.
Medical knowledge and practice change constantly. This book is designed to
provide accurate, authoritative information about the subject matter in
question. However, readers are advised to check the most current information
available on procedures included and check information from the
manufacturer of each product to be administered, to verify the recommended
dose, formula, method and duration of administration, adverse effects and
contraindications. It is the responsibility of the practitioner to take all
appropriate safety precautions. Neither the publisher nor the
author(s)/editor(s) assume any liability for any injury and/or damage to
persons or property arising from or related to use of material in this book.
This book is sold on the understanding that the publisher is not engaged in
providing professional medical services. If such advice or services are
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inadvertently overlooked, the publisher will be pleased to make the necessary
arrangements at the first opportunity.
Inquiries for bulk sales may be solicited at: [email protected]
Review of Pharmacology
Ninth Edition: 2015, Tenth Edition: 2016
Eleventh Edition: 2017, Twelfth Edition: 2018 Thirteenth Edition: 2019
Fourteenth Edition: 2020
ISBN: 978-93-89776-83-6

We want to thank all the readers for the overwhelming response and great
appreciation of the earlier editions of this book. To meet the expectations of
students, we have tried to further improve this new edition.
To meet the constant demand of the students, Dr Gobind Rai Garg has
launched his mobile Application ‘Pharmacology by Dr Gobind Rai Garg’
which is available on both Play store and Apple store. Video lectures of entire
Pharmacology are provided in this App along with many other features. A
massive 25 percentage discount is being offered to esteemed readers of our
book for the subscription of this App.
Cracking the ‘National Eligibility-cum-Entrance Test (NEET)’ and
other important PG entrance examinations require a thorough knowledge
and understanding of the subject. Readers of this book have got an edge over
others because of strong theory and conceptual questions. This along with
the key points given under the headings of various boxes in the chapters has
helped many students to get extremely good ranks in AIIMS, PGI
Chandigarh, All India, JIPMER, NIMHANS and various other PG entrance
examinations. As one-liner questions are being asked in the NEET, the
students need to revise the most important information in the last few days.
Keeping this in mind, we have added golden points at the end of theory of
each chapter. Apart from this, ‘high yield points’ are given separately as
boxes in the text. Boxes are labeled as Key points, for new drugs
and for mnemonics. However, we will recommend students to read the
theory of each topic thoroughly, which is must. The questions have been
asked as one-liners in last year which may not be the case next year and
further in AIIMS and PGI exams you need to be well-versed with the theory.
Therefore, we will re-emphasize that there is no substitution of knowledge. If
you know the subject thoroughly, you can answer any type of question.
N
In our constant endeavour to improvise the book, we have fully colored
the book and added large number of images to make the learning easier and
interesting. There has been incorporation of important additions in almost all
chapters. For quick revision, we have added ‘Golden points’ and ‘Drug of
Choice’ sections in every chapter. Annexures have been added on ‘History of
Pharmacology’, ‘Teratogenic Drugs’ and ‘Drug of Choice’.
In this new edition, we have added a lot of mnemonics, diagrams and
flowcharts to make learning interesting and easier. The question bank of
every chapter has been divided into subtopics. It will help students to solve
MCQs after reading the theory of a particular topic of a chapter. The section
of Image Based Questions has been greatly enhanced to incorporate around
100 such questions. These images have been added chapter-wise to retain
concepts for longer period.
Recently, in several entrance exams, numerical questions are being
asked. To help students to prepare thoroughly for such type of questions,
several numerical questions with explanations have been incorporated in the
chapter of General Pharmacology.
Questions from latest entrance examinations of AIIMS and NEET
pattern have been added.
To make the contents of the book more authentic, we have provided
appropriate references to all the explanations.
In some topics, there are contradictions between different books. In such
a situation, we have quoted the text from Harrison’s Principles of Internal
Medicine, 20th edition.
To help the students understand the Pharmacology in an easy and
interesting way, Dr Gobind Rai Garg has started his own institute named
‘Ayush Institute of Medical Sciences’. It is the only institute which is meant
for teaching Pharmacology only. Dr Gobind Rai Garg himself conducts
separate classes for MBBS students and those preparing for PG entrance
examinations at Delhi and Hyderabad. For details, you can contact on the
www.drgobindraigarg.com/classes.
We must admit hereby that despite keeping an eagle’s eye for any
inaccuracy regarding factual information or typographical errors, some
mistakes must have crept in inadvertently. You are requested to
communicate these errors and send your valuable suggestions for the
improvement of this book. Your suggestions, appreciation and criticism are
most welcome.
Gobind Rai Garg
Sparsh Gupta
E-mail: [email protected]
[email protected]
Pharmacology is one of the most difficult and at the same time most
important subject in various postgraduate entrance examinations.
As we experienced it ourselves, most of the students preparing for
postgraduate entrance examinations are in a dilemma, whether to study
antegrade or retrograde. Antegrade study takes a lot of time and due to bulky
textbooks, some important questions are likely to be missed. In a retrograde
study, the students are likely to answer the frequently asked MCQs but new
questions are not covered. We have tried to overcome the shortcomings of
both of the methods while keeping the advantages intact.
In this book, we have given a concise and enriched text in each chapter
followed by MCQs from various postgraduate entrance examinations and
other important questions likely to come. The text provides the advantage of
antegrade study in a short span of time.
After going through the book, it will be easier for the student to solve the
questions of most recent examinations, which are given at the end of the
book.
More and more questions about new drugs are being asked in the
entrance examinations nowadays. These NEW DRUGS have been covered
along with the text and a separate chapter has been added at the end. Salient
features of the new drugs along with the reference in the text have been
included in this chapter.
Recently, the questions are being asked from SOME EMERGING
TOPICS like anti-obesity drugs, anti-smoking drugs, drugs for erectile
dysfunction and nitric oxide. All these topics have been discussed in a
separate chapter.
Large number of questions about first choice drugs is being incorporated
in the entrance examinations. To cover these questions, a separate chapter
entitled “DRUGS OF CHOICE” has been added.
Important ADVERSE EFFECTS caused by drugs have also been
included.
It is very difficult and at times very confusing to remember large number
of drugs and adverse effects. To make learning easy, several easy to grasp
MNEMONICS have been given throughout the text.
Despite our best efforts, some mistakes might have crept in, which we
request all our readers to kindly bring to our notice. Your suggestions,
appreciation and criticism are most welcome.
Gobind Rai Garg