Oxygen Transport to Tissue XVI

626 Pages·1994·24.391 MB·English

by  C. Bos, L. Hoofd, Z. Turek (auth.), Michael C. Hogan, Odile Mathieu-Costello, David C. Poole, Peter D. Wagner (eds.)

OXYGEN TRANSPORT TO
TISSUE XVI
ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
Editorial Board:
NATHAN BACK, State University of New York at Buffalo
IRUN R. COHEN, The Weizmann Institute of Science
DAVID KRITCHEVSKY, Wistar Institute
ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research
RODOLFO PAOLETTI, University of Milan
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OXYGEN TRANSPORT TO
TISSUE XVI
Edited by
Michael C. Hogan
Odile Mathieu -Costello
David C. Poole
and Peter D. Wagner
University of California, San Diego
La JoIla, California
SPRINGER SCIENCE+BUSINESS MEDIA, LLC
Library of Congr •• s Cataloglng-in-Publicatlon Data
Oxygen transport to tISSU. XVI! edlted by Michael C. Hagan ... let
a1. I .
p. em. -- IAdvanees in experimental med,e,ne and biology v.
361 )
"Proceedings of the 21st annual meeting of the InternatIonal
Society on Oxygen Transport to Tissue, held August 14-18, 1993, In
San Diego, Callf."--T.p. verso.
Includes bibI lographieal references and index.
ISBN 978-1-4613-5763-6 ISBN 978-1-4615-1875-4 (eBook)
DOI 10.1007/978-1-4615-1875-4
1. Tissue respiration--Congresses. I. Hagan, Michael C .• 1954-
11. International Saeiety on Oxygen Transport to Tissue. Meeting
121st 1993 San Diego) 111. Title Oxygen transport to tissue
16. IV. Series.
QP121.Al0992 1994
599' .0 12--de20 94-44823
CIP
Proceedings of the 21 st annual meeting of the International Society on Oxygen Transport to Tissue.
held August 14-18. 1993, in San Diego, California
ISBN 978-1-4613-5763-6
© 1994 Springer Science+Business Media New York
Originally published by Plenum Press in 1994
Softcover reprint of the hardcover 1s t edition 1994
All rights reserved
No part of this book may be reproduced, stored in a retrieval system. or transmitted in any form or by any
means. electronic, mechanical. photocopying. microfilming, recording, or otherwise, without written
permission from the Publisher
INTERNATIONAL SOCIETY ON OXYGEN TRANSPORT TO TISSUE
1992-·1993
Officers
President: P.D. Wagner, U.S.A.
Presidents-Elect: C. Inee, Netherlands and
K. Akpir, Turkey
Past President: P. Vaupel, Germany
Secretary: A. Hudetz, Hungary
Treasurer: S.N. Cain, U.S.A.
Executive Committee
D.F. Bruley, U.S.A. D.T. Delpy, United Kingdom
A. Eke, Hungary T. Goldstick, U.S.A.
K. Groebe, Germany D. Maguire, Australia
H. Metzger, Germany K. Rakusan, Canada
M. Tamura, Japan Z. Turek, The Netherlands
D.F. Wilson, U.S.A. R. Zander, Germany
SAN DIEGO MEETING, AUGUST 14-18, 1993
Organizing Committee
D. Bebout T. Davisson
M. Hogan P. Keipert
J. Lessem O. Mathieu-Costello
D. Poole H. Wagner
P.D. Wagner
v
SPONSORS
We are most grateful for the fInancial support for the 1993 ISOTI Meeting received
from the following:
Alliance Pharmaceutical Corp.
Boehringer Ingelheim Gmbh
Eppendorj-Netheler-Hinz Gmbh
Hospex Fiberoptics
Medical Systems Corp.
Puritan-Bennett Corp.
Triton Technology, Inc.
MedGraphics, Corp.
vii
PREFACE
Since its inception in 1973, The International Society on Oxygen Transport to Tissue
(ISOTT) has provided a unique forum to facilitate and encourage scientific interaction and
debate. Welcoming scientists and clinicians from a broad spectrum of disciplines, each with
their own particular skills and expertise, ISOTT unites them under the common theme of
oxygen transport. The successful blend of scientific presentations and informal discussion
which characterizes ISOTT is epitomized best by the many fundamental discoveries and
technical advancements which it has spawned. The breadth and strengths of The Society's
scientific base promotes the rapid progression of ideas from theoretical concepts to rigorous
scientific testing and often, ultimately to the clinical arena. Each publication of the ISOTT
proceedings has been recognized by Science Citation Index listing and the papers frequently
establish scientific precedents and become considered as standard works in their respective
fields.
The 21st ISOTT Meeting was held in San Diego from August 14th through August 18th,
1993. The San Diego Meeting attracted about 150 registrants and 40 accompanying persons.
Ten state-of-the-art lectures were presented by international experts in ~ transport and there
were in addition two symposia - one dealing with assessment of tissue hypoxia and the other
with functional heterogeneity in different organ systems. There were 100 free
communications, consisting of posters accompanied by an abbreviated oral summary.
All manuscripts were reviewed by the Editors for form and content, but as is customary for
the ISOTT proceedings, rigorous scientific peer review was not undertaken.
The editors congratulate Dr. D.A. Benaron, from Stanford, for the honor of being selected
as the 1993 Melvin Knisely Award Winner for his outstanding contributions in the field of
research on optical imaging in the brain. We also wish to thank Peter Keipert, Eddie
Bebout, Harrieth Wagner, Tania Davisson and Julie Lessem for their tireless help in
mounting the meeting that gave rise to this book.
We look forward to the continued expansion of ISOTI and to the next meeting to be held in
summer 1994 in Istanbul, Turkey.
Michael C. Hogan
Odile Mathieu-Costello
David C. Poole
Peter D. Wagner
March 1994
ix
CONTENTS
THEORETICAL MODELS OF O TRANSPORT
2
Local Plasma Convection Can Be Important for Oxygen Release
in Tissue Capillaries . . . . . . . . . . . . . . . . . .
C. Bos, L. Hoofd, and Z. Turek
Formulation and Realization of a Multicompartmental Model
for 02-C02 Coupled Transport in the Microcirculation 7
G.-F. Ye
Analysis of Tissue Diffusivity using Mathematical Models 17
A. Dutta and A.S. Popel
Computer-Modeling of Oxygen Supply to Cartilage: Addition
of a Compartmental Model ................................. 31
G.-F. Ye and S.F. Silverton
A Program to Calculate Mixed Venous Oxygen Tension - A
Guide to Transfusion? .................................... 41
N.S. Faithfull, G.E. Rhoades, P.E. Keipert, A.S. Ringle, and A. Trouwborst
Microcirculation and O Exchange through the Skin Surface. A
2
Theoretical Analysis ................... . . . . . . . . . . . . . .. 51
D.W. Lubbers
Abstracts:
Fractal Approaches to the Microcirculation ............................ 59
LB. Bassingthwaighte, L. Young, R.P. Beyer, and C. Y. Wang
METHODS AND INSTRUMENTA TION
A. Phosphorescence Quenching:
Recent Advances in Oxygen Measurements using Phosphorescence
Quenching ........................................... 61
D.F. Wilson and S.A. Vinogradov
xi
Recovery of Oxygen Distributions in Tissue from Phosphorescence
Decay Data ............................ . 67
S.A. Vinogradov and D.F. Wilson
A New Phosphorimeter for the Measurement of Oxygen Pressures
using PD-Porphine Phosphorescence ........... . 75
M. Sinaasappel, C. Ince, J.P. van der Sluijs, and H.A. Bruining
Imaging Oxygen Pressure in Tissue In Vivo by Phosphorescence
Decay ............................................. 83
M. Pawlowski and D.F. Wilson
Measurement of Oxygen Pressure in the Heart In Vivo using
Phosphorescence Quenching . . . . . . . . . . . . . . . . 93
W.L. Rumsey, M. Pawlowski, N. Lejavardi, and D.F. Wilson
Detecting Hypoxia in Heart using Phosphorescence Quenching
and 99MTechnetium-Nitromidazoles ............................ 99
W.L. Rumsey, B. Kuczynski, and B. Patel
Intestinal Ischemia during Hypoxia and Experimental Sepsis as
Observed by NADH Videofluorimetry and
Quenching of PD-Porphine Phosphorescence . . . . . . . . . . . . . .. 105
C. Ince, J.P. van der Sluijs, M. Sinaasappel,
1.A.M. Avontuur, J.M.C.C. Coremans, and H.A. Bruining
B. Magnetic Resonance Techniques:
IH NMR Approach to Observe Tissue Oxygenation with the
Signals of Myoglobin ............. . . . . . . . . . . . . . . . . . . . . . . . III
T. lue, U. Kreutzer, and Y. Chung
Measurements of P02 In Vi~o, including Human Subjects by
Electron ParamagnetIc Resonance ........... ................ 119
H.M. Swartz, G. Bacic, B. Friedman, F. Goda, O. Grinberg,
P.I. Hoopes, J. Jiang, K.1. Liu, T. Nakashima,
1. O'Hara, and T. Walczak
Half-Life of Perfluorooctylbromide in Inner Organs Determined
by Fast 19F-NMR Imaging ................................. 129
L.J.E. Jager, U. N6th, A. Haase, and 1. Lutz
C. Near Infrared Spectroscopy:
Frequency Response by Pulse Reduction for the Analysis of
TRS Spectra ...................... .. . . . . . . . . . . . . . . . 135
K.A. Kang, D.F. Bruley, J.M. Londono, and B. Chance
An Automated System for the Measurement of the Response of
Cerebral Blood Volume and Cerebral Blood Flow
to Changes in Arterial Carbon Dioxide Tension
using Near Infrared Spectroscopy ....... . .................. 143
C.E. Elwell, M. Cope, D. Kirkby, H. Owen-Reece,
C.E. Cooper, E.O.R. Reynolds, and D.T. Delpy
xii
Near Infrared Spectroscopy: In Situ Studies of Skeletal and
Cardiac Muscle ....................................... 157
C.A. Piantadosi and F.G. Duhaylongsod
D. Other:
Digital Imaging of the Oxygenation State within an Isolated Single
Rat Cardiomyocyte ..................................... 163
E. Takahashi and K. Doi
Optical Imaging of Human Breast Cancer ............................ 171
S. Nioka, M. Miwa, S. Orel, M. Shnal!, M. Haida,
S. Zhao, and B. Chance
Transcutaneous H2 Clearance - A New Least-Invasive Method for
Assessing Skin Blood Flow ................. . ............ 181
D.K. Harrison, R.A. Raad, D.J. Newton, and P.T. McCollum
Measurement of Cardio-Respiratory Function using Single Frequency
Inspiratory Gas Concentration Forcing Signals .................... 187
E.M. Williams and C.E.W. Hahn
Optical Oxygen Sensor using Fluorescence Lifetime Measurement ....... . . . . .. 197
S. Bambot, R. Holavanahali, J.R. Lakowicz, G.M. Carter,
and G. Rao
Tomographic Time-of-Flight Optical Imaging Device .. . . . . . . . . . . . . . . . . . . . 207
D.A. Benaron, D.C. Ho, S. Spilman, J.P. Van Houten,
and D.K. Stevenson
Non-Recursive Linear Algorithms for Optical Imaging in Diffusive Media ........ 215
D.A. Benaron, D.C. Ho, S. Spilman, J.P. Van Houten,
and D.K. Stevenson
Abstracts:
Results of Optical Imaging of Brain Pathology 223
D.A. Benaron
Forearm Blood Flow Measurement by Near Infrared Spectroscopy 224
R.A. De Blasi, M. Ferrari, G. Conti, A. Mega, and
A. Gasparetto
Object Localization in Brain and Breast by a Phased Array System 225
B. Chance, .K. Kang, and L. He
Mitochondrial Redox State as a "Gold Standard" of Tissue Hypoxia 226
B. Chance
Development of a Closed Circuit System for Pediatric Anesthesia
and On-Line V02 Monitoring ............ . 227
E.P. Eijking, J. Bezstarosti, B. Westerkamp, G. van Dijk,
A.E.E. Meursing, and W. Erdmann
xiii