Table Of Content

NEUROPHARMACOLOGY CONTENTS OF VOLUME 45 NUMBER | Mini-review K.K. Dev, H. van der Putten, B. Sommer, Part I: Parkin-associated proteins and Parkinson's disease G. Rovelli Mini-review K.K. Dev, K. Hofele, S. Barbieri, Part Il: a-synuclein and its molecular pathophysiological role in neurodegenerative V.L. Buchman, H. van der Putten disease Mini-review A. Pisani, P. Bonsi, D. Centonze, largeting striatal cholinergic interneurons in Parkinson’s disease: Focus on P. Gubellini, G. Bernardi, P. Calabresi metabotropic glutamate receptors D. Belelli, A.-L. Muntoni, $.D. Merrywest, lhe in vitro and in vivo enantioselectivity of etomidate implicates the GABA, receptor L.JjJ. Gentet, A. Casula, H. Callachan, in general anaesthesia P. Madau, D.K. Gemmell, N.M. Hamilton, J.J. Lambert, K.T. Sillar, J.A. Peters M. Hajos, S.E. Gartside, V. Varga, In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by T. Sharp midbrain-raphe nuclei: role of 5-HT,, receptors P. Sanchez-Blazquez, M. Rodriguez-Diaz, The GBeta5 subunit that associates with the R7 subfamily of RGS proteins regulates A. Lopez-Fando, M. Rodriguez-Mujfioz, mu-opioid effects J. Garzon T. Minami, S. Matsumura, T. Mabuchi, Functional evidence for interaction between prostaglandin EP3 and x-opioid receptor T. Kobayashi, Y. Sugimoto, F. Ushikubi, pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) A. Ichikawa, S. Narumiya, S. Ito glycoprotein gp120 C. Achat-Mendes, K.L. Anderson, Methylphenidate and MDMA adolescent exposure in mice: Long-lasting consequences Y. Itzhak on cocaine-induced reward and psychomotor stimulation in adulthcod T. Nakatsuka, H.-X. Chen, S.N. Roper, Cannabinoid receptor-! activation suppresses inhibitory synaptic activity in human J.G. Gu dentate gyrus S. Miksys, C. Lerman, P.G. Shields, Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain D.C. Mash, R.F. Tyndale M. Ihara, K. Matsuda, M. Otake, Diverse actions of neonicotinoids on chicken a7, a482 and Drosophila—chicken M. Kuwamura, M. Shimomura, SADB2 and ALSB2 hybrid nicotinic acetylcholine receptors expressed in Xenopus K. Komai, M. Akamatsu, V. Raymond, laevis oocytes D.B. Sattelle K.S. Vasiljev, A. Uri, J.T. Laitinen Alkylthio-substituted platelet P2Y,, receptor antagonists reveal pharmacological identity between the rat brain G,-linked ADP receptors and P2Y NUMBER 2 G. Battaglia, C.L. Busceti, F. Pontarelli, Protective role of group-Il metabotropic glutamate receptors against nigro-striatal F. Biagioni, F. Fornai, A. Paparelli, Gegeneration induced by |-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice V. Bruno, S. Ruggieri, F. Nicoletti A. Mork, M. Kreilgaard, C. Sanchez The R-enantiomer of citalopram counteracts escitalopram-induced increase in extracellular 5-HT in the frontal cortex of freely moving rats L. Leriche, J.-C. Schwartz, P. Sokoloff The dopamine D, receptor mediates locomotor hyperactivity induced by NMDA receptor blockade C. Pardini, F. Vaglini, S. Galimberti, Dose-dependent induction of apoptosis by R-apomorphine in CHO-K1 cell line in G.U. Corsini culture A. Seillier, E. Coutureau, N. Thiriet, Bilateral lesions of the entorhinal cortex differentially modify haloperidol- and K. Herbeaux, J. Zwiller, G. Di Scala, olanzapine-induced c-fos MRNA expression in the rat forebrain B. Will, M. Majchrzak M. Marcoli, L. Raiteri, A. Bonfanti, Sensitivity to selective adenosine A, and A,, receptor antagonists of the release of A. Monopoli, E. Ongini, M. Raiteri, glutamate induced by ischemia in rat cerebrocortical slices G. Maura P.J. Scarpace, M. Matheny, Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin S. Zolotukhin, N. Tiimer, Y. Zhang agonist MT II NEUROPHARMACOLOGY CONTENTS OF VOLUME 45 NUMBER | Mini-review K.K. Dev, H. van der Putten, B. Sommer, Part I: Parkin-associated proteins and Parkinson's disease G. Rovelli Mini-review K.K. Dev, K. Hofele, S. Barbieri, Part Il: a-synuclein and its molecular pathophysiological role in neurodegenerative V.L. Buchman, H. van der Putten disease Mini-review A. Pisani, P. Bonsi, D. Centonze, largeting striatal cholinergic interneurons in Parkinson’s disease: Focus on P. Gubellini, G. Bernardi, P. Calabresi metabotropic glutamate receptors D. Belelli, A.-L. Muntoni, $.D. Merrywest, lhe in vitro and in vivo enantioselectivity of etomidate implicates the GABA, receptor L.JjJ. Gentet, A. Casula, H. Callachan, in general anaesthesia P. Madau, D.K. Gemmell, N.M. Hamilton, J.J. Lambert, K.T. Sillar, J.A. Peters M. Hajos, S.E. Gartside, V. Varga, In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by T. Sharp midbrain-raphe nuclei: role of 5-HT,, receptors P. Sanchez-Blazquez, M. Rodriguez-Diaz, The GBeta5 subunit that associates with the R7 subfamily of RGS proteins regulates A. Lopez-Fando, M. Rodriguez-Mujfioz, mu-opioid effects J. Garzon T. Minami, S. Matsumura, T. Mabuchi, Functional evidence for interaction between prostaglandin EP3 and x-opioid receptor T. Kobayashi, Y. Sugimoto, F. Ushikubi, pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) A. Ichikawa, S. Narumiya, S. Ito glycoprotein gp120 C. Achat-Mendes, K.L. Anderson, Methylphenidate and MDMA adolescent exposure in mice: Long-lasting consequences Y. Itzhak on cocaine-induced reward and psychomotor stimulation in adulthcod T. Nakatsuka, H.-X. Chen, S.N. Roper, Cannabinoid receptor-! activation suppresses inhibitory synaptic activity in human J.G. Gu dentate gyrus S. Miksys, C. Lerman, P.G. Shields, Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain D.C. Mash, R.F. Tyndale M. Ihara, K. Matsuda, M. Otake, Diverse actions of neonicotinoids on chicken a7, a482 and Drosophila—chicken M. Kuwamura, M. Shimomura, SADB2 and ALSB2 hybrid nicotinic acetylcholine receptors expressed in Xenopus K. Komai, M. Akamatsu, V. Raymond, laevis oocytes D.B. Sattelle K.S. Vasiljev, A. Uri, J.T. Laitinen Alkylthio-substituted platelet P2Y,, receptor antagonists reveal pharmacological identity between the rat brain G,-linked ADP receptors and P2Y NUMBER 2 G. Battaglia, C.L. Busceti, F. Pontarelli, Protective role of group-Il metabotropic glutamate receptors against nigro-striatal F. Biagioni, F. Fornai, A. Paparelli, Gegeneration induced by |-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice V. Bruno, S. Ruggieri, F. Nicoletti A. Mork, M. Kreilgaard, C. Sanchez The R-enantiomer of citalopram counteracts escitalopram-induced increase in extracellular 5-HT in the frontal cortex of freely moving rats L. Leriche, J.-C. Schwartz, P. Sokoloff The dopamine D, receptor mediates locomotor hyperactivity induced by NMDA receptor blockade C. Pardini, F. Vaglini, S. Galimberti, Dose-dependent induction of apoptosis by R-apomorphine in CHO-K1 cell line in G.U. Corsini culture A. Seillier, E. Coutureau, N. Thiriet, Bilateral lesions of the entorhinal cortex differentially modify haloperidol- and K. Herbeaux, J. Zwiller, G. Di Scala, olanzapine-induced c-fos MRNA expression in the rat forebrain B. Will, M. Majchrzak M. Marcoli, L. Raiteri, A. Bonfanti, Sensitivity to selective adenosine A, and A,, receptor antagonists of the release of A. Monopoli, E. Ongini, M. Raiteri, glutamate induced by ischemia in rat cerebrocortical slices G. Maura P.J. Scarpace, M. Matheny, Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin S. Zolotukhin, N. Tiimer, Y. Zhang agonist MT II List of Contents for Volume 45 / Neuropharmacology 45 (2003) XXIV-XXVIII L.J. Sim-Selley, L.J. Vogt, S.R. Childers, Distribution of ORL-1 receptor binding and receptor-activated G-proteins in rat B.A. Vogt forebrain and their experimental localization in anterior cingulate cortex N.M.J. Rupniak, E.J. Carlson, Comparison of the functional blockade of rat substance P (NK,) receptors by S. Shepheard, G. Bentley, A.R. Williams, GR205171, RP67580, SR140333 and NKP-608 A. Hill, C. Swain, S.G. Mills, J. Di Salvo, R. Kilburn, M.A. Cascieri, M.M. Kurtz, K.-L. Tsao, S.L. Gould, G.G. Chicchi R.A. Duffy, J.A. Hedrick, G. Randolph, Centrally administered hemokinin-!| (HK-1), a neurokinin NKI receptor agonist C.A. Morgan, M.E. Cohen-Williams, produces substance P-like behavioral effects in mice and gerbils G. Vassileva, J.E. Lachowicz, M. Laverty, M. Maguire, L.-S. Shan, E. Gustafson, G.B. Varty H. Okamoto, Y. Shino, K. Hashimoto, Dynamic changes in AP-1! transcription factor DNA binding activity in rat brain C. Kumakiri, E. Shimizu, H. Shirasawa, following administration of antidepressant amitriptyline and brain-derived M. lyo neurotrophic factor L. Sterin-Borda, S. Ganzinelli, A. Berra, Novel insight into the mechanisms involved in the regulation of the ml muscarinic E. Borda receptor, INOS and nNOS mRNA levels L. Zhu, Z.L. Jiang, K. Krnjevic, Genistein directly blocks glycine receptors of rat neurons freshly isolated from the F.S. Wang, J.H. Ye ventral tegmental area L. Liu, P.K. Gonzalez, C.F. Barrett, The calcium channel ligand FPL 64176 enhances L-type but inhibits N-type neuronal A.R. Rittenhouse calcium currents NUMBER 3 4. Hamon, A. Morel, B. Hue, M. Verleye, The modulatory effects of the anxiolytic etifoxine on GABA, receptors are mediated J.-M. Gillardin by the 6 subunit M. Sugimoto, I. Uchida, T. Mashimo, Evidence for the involvement of GABA, receptor blockade in convulsions induced S. Yamazaki, K. Hatano, F. Ikeda, by cephalosporins Y. Mochizuki, T. Terai, N. Matsuoka K.K. Borowicz, S.J. Czuczwar Effects of etomidate, ketamine or propofol, and their combinations with conventional antiepileptic drugs on amygdala-kindled convulsions in rats M.S. Cowen, K.-C. Schroff, P. Gass, Neurobehavioral effects of alcohol in AMPA receptor subunit (GluR1) deficient mice R. Sprengel, R. Spanagel Y. Chen, T.J.W. Sharples, K.G. Phillips, The nicotinic a4f82 receptor selective agonist, TC-2559, increases dopamine neuronal G. Benedetti, L.M. Broad, R. Zwart, activity in the ventral tegmental area of rat midbrain slices ¥. Sher H. Kim, B.A. Flanagin, C. Qin, The mouse Chrna4 A529T polymorphism alters the ratio of th to low affinity R.L. Macdonald, J.A. Stitzel a4B2 nAChRs M.E. Gibbs, R.J. Summers a@,-adrenoceptors in the basal ganglia have a role in memory consolidation anc reinforcement A. Haji, M. Okazaki, Y. Ohi, Biphasic effects of morphine on bulbar respiratory neuronal activities in decerebrate H. Yamazaki, R. Takeda cats J. Wang, R.V. Lloyd Faulconbridge, Local application of sodium thiosulfate prevents cisplatin-induced hearing loss in the A. Fetoni, M.J. Guitton, R. Pujol, guinea pig J.L. Puel M. Muramoto, T. Yamazaki, Detailed in vitro pharmacological analysis of FK506-induced neuroprotection S. Nishimura, Y. Kita D.M. Sokal, S.J.R. Elmes, D.A. Kendall, Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal V. Chapman neurones via activation of CB, receptors in anaesthetised rats E. Alfonso Romero-Sandoval, The effects of sham and full spinalization on the antinociceptive effects of NCX-701 P. Del Soldato, J.F. Herrero (nitroparacetamol) in monoarthritic rats L.M.T. Canzoniero, P. Manzerra, Membrane-permeant chelators can attenuate Zn-*-induced cortical neuronal C.T. Sheline, D.W. Choi P. N’Gouemo, M. Morad Ethanol withdrawal seizure susceptibility is associated with upregulation P-type Ca°* channel currents in rat inferior colliculus neurons List of Contents for Volume 45 / Neuropharmacology 45 (2003) XXIV-XXVIII NUMBER 4 Mini-reviews L.L. Voronin, E. Cherubini “Presynaptic silence” may be golden J.T.R. Isaac Postsynaptic silent synapses: evidence and mechanisms K.J. Crossley, I. Nitsos, D.W. Walker, Steroid-sensitive GABA, receptors in the fetal sheep brain A.J. Lawrence, P.M. Beart, J.J. Hirst A.-M. Linden, M. Bergeron, M. Baez, Systemic administration of the potent mGlu8 receptor agonist (S)-3,4-DCPG induces D.D. Schoepp c-Fos in stress-related brain regions in wild-type, but not mGlu8 receptor knockout mice K. Gotembiowska, J. Konieczny, Neuroprotective action of MPEP, a_ selective mGluR5 antagonist, in S. Wolfarth, K. Ossowska methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats R.E. Moo-Puc, J.L. Gongora-Alfaro, Caffeine and muscarinic antagonists act in synergy to inhibit haloperidol-induced F.J. Alvarez-Cervera, J.C. Pineda, catalepsy G. Arankowsky-Sandoval, F. Heredia-Lopez M. Yigit, C. Keipert, K.H. Backus Muscarinic acetylcholine receptors potentiate the GABAergic transmission in the developing rat inferior colliculus Y. Fu, S.G. Matta, V.B. Kane, Norepinephrine release in amygdala of rats during chronic nicotine self-administration B.M. Sharp an in vivo microdialysis study L. Dayan, J.P.M. Finberg L-DOPA increases noradrenaline turnover in central and peripheral nervous systems S. Demehri, H. Homayoun, H. Honar, Agmatine exerts anticonvulsant effect in mice: modulation by @,-adrenoceptors and K. Riazi, K. Vafaie, F. Roushanzamir, nitric oxide A.R. Dehpour C.M. Cahill, A. Dray, T.J. Coderre Intrathecal nerve growth factor restores opioid effectiveness in an animal model of neuropathic pain B.G. Dias, S.B. Banerjee, R.S. Duman, Differential regulation of Brain Derived Neurotrophic Factor transcripts by V.A. Vaidya antidepressant treatments in the adult rat brain NUMBER 5 M.F. O'Neill, C. Heron-Maxwell, Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 M.W. Conway, J.A. Monn, P. Ornstein increase locomotor activity in mice S.P. Hack, C.W. Vaughan, Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro M.J. Christie P.J. Mallorga, J.B. Williams, Pharmacology and expression analysis of glycine transporter GlyT1 with [*H]-(N-[3 M. Jacobson, R. Marques, A. Chaudhary, (4 -fluorophenyl)-3-(4 phenylphenoxy )propyl])sarcosine P.J. Conn, D.J. Pettibone, C. Sur D.P. Finn, M.D. Jhaveri, S.R.G. Beckett, Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist C.H. Roe, D.A. Kendall, C.A. Marsden, on nociceptive and aversive responses in rats V. Chapman F.J.-P. Miao, P. Green, N. Benowitz, Vagal modulation of spinal nicotine-induced inhibition of the inflammatory response J.D. Levine mediated by descending antinociceptive controls Z.-L. Yang, Y.-J. Gao, G.-C. Wu, The rostral ventromedial medulla mediates the facilitatory effect of microinjected Y.-Q. Zhang orphanin FQ in the periaqueductal gray on spinal nociceptive transmission in rats L. Facci, D.A. Stevens, M. Pangallo, Corticotropin-releasing factor (CRF) and related peptides confer neuroprotection via D. Franceschini, S.D. Skaper, type 1 CRF receptors P.J.L.M. Strijbos N. Nakamichi, G. Chidlow, N.N. Osborne Effects of intraocular injection of a low concentration of zinc on the rat retina G.X. Ayala, R. Tapia Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate- mediated excitotoxic stress in rat hippocampus in vivo M. Madeja, D.G. Margineanu, A. Gorji, Reduction of voltage-operated potassium currents by levetiracetam: a novel E. Siep, P. Boerrigter, H. Klitgaard, antiepileptic mechanism of action? E.-J. Speckmann .«G. Jorda, E. Verdaguer, A.M. Canudas, Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in Jiménez, A. Bruna, C. Caelles, colchicine-induced apoptosis Bravo, E. Escubedo, D. Pubill, J. Camarasa, M. Pallas, A. Camins O. De Backer, P.G. Leclere, Pharmacological characterization of pre- and postsynaptic prostanoid receptors in pig R.A. Lefebvre gastric fundus List of Contents for Volume 45 / Neuropharmacology 45 (2003) XXIV-XXVIII E. Brailoiu, M.D. Miyamoto, N.J. Dun Inositol derivatives modulate spontaneous transmitter neuromuscular junction NUMBER 6 Post-Translational Modifications of Protein Structure and Synaptic Function G.L. Snyder, S. Galdi, A.A. Fienberg, Regulation of AMPA receptor dephosphorylation by glutamate receptor agonist P. Allen, A.C. Nairn, P. Greengard Y. Zhou, H. Fei, LB. Levitan An interaction domain in Slob necessary for its binding to the slowpoke calcium dependent potassium channel L.V. Kalia, M.W. Salter Interactions between Sre family protein tyrosine kinases and PSD-95 G. Lavezzari, J. McCallum, R. Lee, Differential binding of the AP-2 adaptor complex and PSD-95 to the C-terminu K.W. Roche the NMDA receptor subunit NR2B regulates surface expression 1.A. Lim, M.A. Merrill, Y. Chen, Disruption of the NMDA receptor—-PSD-95 interaction in hippocampal neurons with J.W. Hell no obvious physiological short-term effect D.B. Scott, T.A. Blanpied, M.D. Ehlers Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors M.E. Grunwald, J.M. Kaplan Mutations in the ligand-binding and pore domains control exit of glutamat from the endoplasmic reticulum in C. e/egan M.F. Matos, K. Mukherjee, X. Chen, Evidence for SNARE zippering during Ca**-triggered exocytosis in P¢ J. Rizo, T.C. Siidhof K. Farsad, V. Slepnev, G. Ochoa, A putative role for intramolecular regulatory mechanisms in the adaptor function of L. Daniell, V. Hauke, P. De Camilli amphiphysin in endocytosis A.M. Aravanis, J.L. Pyle, N.C. Harata, Imaging single synaptic vesicles undergoing repeated fusion events: kissing, running R.W. Tsien and kissing again C. Canti, A.C. Dolphin CayB subunit-mediated up-regulation of Cay2.2 currents trigg by D2 dopamine receptor activation M.A. Wikstrém, P. Matthews, D. Roberts, Parallel kinase cascades are involved in the induction of LTP at hippocampal CAI] G.L. Collingridge, Z.A. Bortolotto synapses N.L. Stricker, R.L. Huganir The PDZ domains of mLin-10 regulate its trans-Golgi network targeting and the surface expression of AMPA receptors S. Dakoji, S. Tomita, S. Karimzadegan, Interaction of transmembrane AMPA receptor regulatory proteins with multiple R.A. Nicoll, D.S. Bredt membrane associated guanylate kinases M.F.A. Finley, R.H. Scheller, SNAP-25 Serl87 does not mediate phorbol ester enhancement of hippocampal D.V. Madison synaptic transmission S. Endo, T. Launey ERKs regulate PKC-dependent synaptic depression and declustering of glutamate receptors in cerebellar Purkinje cells S.C. Harney, B.G. Frenguelli, Phosphorylation influences neurosteroid modulation of synaptic GABA, receptors in J.J. Lambert rat CAI and dentate gyrus neurones NUMBER 7 J.V. Selkirk, G.S. Naeve, A.C. Foster Blockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group | and group III metabotropic glutamate receptors M. Maj, V. Bruno, Z. Dragic, (—)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism R. Yamamoto, G. Battaglia, of action, and neuroprotection W. Inderbitzin, N. Stoehr, T. Stein, F. Gasparini, I. Vranesic, R. Kuhn, F. Nicoletti, P.J. Flor M.O. Cunningham, G.L. Woodhall, Valproate modifies spontaneous excitation and inhibition at cortical synapses in vitro R.S.G. Jones R.J. Racine, M. Steingart, Y. Bureau, Differential sensitivity of genetically Fast vs. Slow kindling rats strains to GABAergic D.C. McIntyre convulsive agents G. Fairchild, M.M. Leitch, C.D. Ingram Acute and chronic effects of corticosterone on 5-HT,, receptor-mediated autoinhibition in the rat dorsal raphe nucleus XXVIII List of Contents for Volume 45 / Neuropharmacology 45 (2003) XXIV-XXVIII1 S. Koch, S.K. Hemrick-Luecke, Comparison of effects of dual transporter inhibitors on monoamine transporters and L.K. Thompson, D.C. Evans, extracellular levels in rats P.G. Threlkeld, D.L. Nelson, K.W. Perry, F.P. Bymaster D. Moison, P. De Deurwaerdere, Intrastriatal administration of sigma ligands inhibits basal dopamine release in vivo A. Cagnotto, A. Marrazzo, O. Prezzavento, G. Ronsisvalle, T. Mennini, U. Spampinato P. Samadi, L. Grégoire, P.J. Bédard Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: interaction between dopamine and opioid systems F. Gumilar, H.R. Arias, G. Spitzmaul, Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic C. Bouzat antidepressants M. El Yacoubi, C. Ledent, M. Parmentier, Caffeine reduces hypnotic effects of alcohol through adenosine A,, receptor blockade J. Costentin, J.-M. Vaugeois Y.-S. Lau, E. Petroske, G.E. Meredith, Elevated neuronal nitric oxide synthase expression in chronic haloperidol-treated rats 986 J.Q. Wang B.L. MacInnis, D.L. Senger, Spatial requirements for TrkA kinase activity in the support of neuronal survival and 995 R.B. Campenot axon growth in rat sympathetic neurons H. Jiang, T. Xie, D.B. Ramsden, S.L. Ho Human catechol-O-methyltransferase down-regulation by estradiol 1011 S. Horie, S. Yasuda, Y. Tsurumaki, Contraction of isolated guinea-pig ileum by urotensin II via activation of ganglionic 1019 A. Someya, T. Saito, Y. Okuma, cholinergic neurons and acetylcholine release Y. Nomura, T. Hirabayashi, T. Murayama NUMBER 8 D. Pau, D. Belelli, H. Callachan, GABA, receptor modulation by the novel intravenous general anaesthetic E-6375 D.R. Peden, J.1. Dunlop, J.A. Peters, X. Guitart, B. Gutierrez, J.J. Lambert M.J. Regina, J.C. Winter, R.A. Rabin Characterization of a novel effect of serotonin 5-H1T and 5-HT receptors 104] increasing CGMP levels in rat frontal cortex Y. Ago, Y. Koyama, A. Baba, T. Matsuda Regulation by 5-HT receptors of the in vivo release of 5-HT and DA in mouse 1050 frontal cortex E. Lorenc-Koci, J. Wardas, Contribution of the serotonin 5-HT,, receptor agonism of 8-OH-DPAT and EMD 1057 G.D. Bartoszyk, S. Wolfarth 128130 to the regulation of haloperidol-induced muscle rigidity in rats D. Arcos, A. Sierra, A. Nunez, G. Flores, Noradrenaline increases the firing rate of a subpopulation of rat subthalamic neurones 1070 J. Aceves, J.-A. Arias-Montaiio through the activation of a,-adrenoceptors M.D. Monte, C. Petrucci, A. Vasilaki, Genetic deletion of somatostatin receptor | alters somatostatinergic transmission in 1080 D. Cervia, D. Grouselle, J. Epelbaum, the mouse retina H.-J. Kreienkamp, D. Richter, D. Hoyer, P. Bagnoli R. Suzuki, S.P. Hunt, A.H. Dickenson The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice 1.J. Lever, A.D. Grant, S. Pezet, Basal and activity-induced release of substance P from primary afferent fibres in NK N.P. Gerard, S.D. Brain, M. Malcangio receptor knockout mice: evidence for negative feedback R. Radhakrishnan, K.A. Sluka Spinal muscarinic receptors are activated during low or high frequency TENS-induced antihyperalgesia in rats I. Glezer, C.D. Munhoz, E.M. Kawamoto, MK-8O1 and 7-Ni attenuate the activation of brain NF-KB induced by LPS T. Marcourakis, M.C.W. Avellar, C. Scavone M.-S. Song, E.I. Posse de Chaves Inhibition of rat sympathetic neuron apoptosis by ceramide. Role of p7 ceramide generation C.D. Munhoz, |. Glezer, E.M. Kawamoto, Changes in sodium, potassium-ATPase induced by repeated fencamfamine: the roles A.P.N. Aratijo, L.B. Lepscha, of cyclic AMP-dependent protein kinase and the nitric oxide—cyclic GMP pathway C.S. Planeta, R. DeLucia, C. Scavone J.V. Selkirk, G.S. Naeve, A.C. Foster Biockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group I and group III metabotropic glutamate receptors Volumes 44 and 45 Contents, Author and Subject Indices