Table Of Content

Author index of volume 344 A E Hisatome I, 331 Lin-Shiau SY, 691 Hortnagel H, 213 Lister RG, 252 Abel KC, 220 Ebinger G, 514 Hoffmann WE, 263 Litsch K, 720 Adaniya H, 323 Eglen RM, 29 Hornykiewicz O, 213 Lum JT, 263 Agmo A, 314 Eichler HG, 302 Hoyer D, 137 Lunardi G, 275 Ahnert-Hilger G, 387 Ekman A, 263 Hsu F, 454 Albino-Teixeira A, 36 Endoh M, 70 Huck S, 130, 382 Allgaier C, 187 Engberg G, 16 Huff RM, 509 Altiok N, 611 Erne P, 706 Maclagan J, 403 Altura BM, 193 Ertl R, 574 Mannisto PT, 412 Altura BT, 193 Ervens J, 396 Manley SW, 220 Amemiya Y, 454 Evans DL, 509 Iguchi M, 133 Mantegazza P, 84 Amenta F, 259 lkeda M, 247 Mantelli L, 464 Amerini S, 464 F Imai S, 235 Marchi M, 275 Augliera A, 275 Azevedo |, 36, 41 FashempourJ , 454 IshibashiT , 235 Martel F, 36 Fedele E, 275 Ito H, 133 Martin-Iverson MT, Feller DR, 454 Ito K, 247 281 Ferrar JA, 557 Marxen P, 387 Bartels F, 387 Ferrario P, 84 J Mashiba H, 331 Bassant MH, 568 Feth F, 1 Matsuki N, 564 Batink HD, 107 Figur LM, 509 Jackson WF, 345 Matthews ML, 449 Berger F, 653 Fink K, 167 Jacobson KA, 639 Mayer E, 297 Berger ML, 213 Forster S, 240 Jahnel U, 574 Mende U, 90 Bernauer W, 544 Fontana G, 275 Jazat F, 568 Meyer W, 90 Biediger AM, 47 Forderkunz S, 682 Michel MC, 1 Michotte Y, 514 BBiirgnasltkieel HS,, 37897 FForxe dAhJo,l m 8 BB, 611 K Miller DD, 454 Blier P, 160 Fricke U, 337,488 Kalmar P, 90 Mizumura K, 368 Blochl-Daum B, 302 Fu WM, 691 Kammer T, 653 Molderings GJ, 630 Blumberg PM, 551 Furukawa T, 582 Karaki H, 602 Moon MW, 509 Boeckxstaens GE, 716 Katori R, 331 Moormann M, 114 Bohm S, 130 Kaumann AJ, 56, 150 Morel N, 698 Boehm S, 382 G Keeton TK, 47, 308 Morgan PF, 252 Bogers JJ, 716 Godfraind T, 698 Kenakin TP, 201 Morton IKM, 8, 225 Borchard U, 653 Gothert M, 167, 630 Khamssi M, 430 Moura D, 41 Boselli C, 201 Gomita Y, 500 Kilbinger H, 143 Murray KJ, 150 Bourke JR, 220 Goncalves J, 532 Kinoshita K, 247 Bray K, 351 Graefe K-H, 720 Klaus W, 488 Brenn T, 527 Greber R, 187 Klein A, 403 Brinkmeier H, 596 Green RD, 639 Kojda G, 337 Nagashima S, 478 Brodde OE, 430 Guimaraes S, 532 Korn A, 302 Nakajima T, 133 Brown AM, 150 Gutiérrez M, 314 Kotake H, 331 Nakashima M, 478 Brown L, 220 Guzman M, 314 Kraus W, 337 Nawrath H, 574 Brown MJ, 150 Kromer W, 360 Nebel U, 101 Bultmann R, 174 Kruk ZL, 623 Neumann J, 90 Busse R, 126, 345 H Kugelgen I von, 174, Nishimoto M, 478 Haas HL, 79 419 Nissbrandt H, 16 Haass M, 527 Kumazawa T, 368 Nordstedt C, 611 Cc Habuchi Y, 582 Kuo YJJ, 308 Norota |, 70 Carlsson A, 263 Hafner B, 84 Kurachi Y, 133 Nose M, 90 Carmeliet E, 574, 662 Hafner D, 653 Kushida H, 70 Codignola A, 275 Halbriigge T, 619, 720 Kvanta A, 611 Oo Conci F, 84 Hall JM, 225 Constantine JW, 471 Hamada A, 454 Oishi R, 500 L Cox HM, 557 Hamada E, 133 Osswald W, 36 Cragoe EJ Jr, 220 Hamaguchi M, 235 Lahti RA, 509 Ozaki H, 602 Harris GC, 29 Lamontagne D, 126 Ozaki T, 478 Hatzelmann A, 682 Lamour Y, 568 D Haverich A, 90 Langeloh A, 619 P Day SY, 691 Hayafuji M, 582 Lebel WS, 471 De Man JG, 716 Heiningen PNM van, Ledda F, 464 Palluk R, 119 Deleu D, 514 107 Lee BH, 568 Patil PN, 454 Delpon E, 645 Heistracher M, 183 Lemoine H, 56 Pazzagli M, 538 DeLuca A, 596 Hentrich F, 630 Leung E, 639 Pedata F, 538 Doring V, 90 Herman AG, 716 Leyen H von der, 90 Pegg GG, 442, D’Oréans-Juste P, 505 Hermsmeyer K. 706 Limberger N, 623 Pelckmans PA, 716 Drobny H, 130 Hertting G, 187 Lindsay DB, 442, 449 Pepeu G, 538 Durcan MJ, 252 Hiraoka M, 323 Linnoila M, 252 Peskar BA, 495 Vill Peters T, 101 Sanchez-Chapula J, Svensson K, 263 Ww Pfaffendorf M, 114 645 Szallasi A, 551 Wang JP, 377 Pfister JR, 29 Sanders L, 150 Szallasi Z, 551 Weis T, 653 Philippu A, 183 Sarre S, 514 Szolcsanyi J, 551 Wenzel-Seifert K, 396 Piercey MF, 263 Sasaki N, 331 Pileblad E, 16 Sato J, 368 T Wenzlaff H, 90 Wermelskirchen D, 101 Ploeg | van der, 611 Sato K, 602 Taira N, 589 Werner G, 337, 488 Pohan D, 403 Sato R, 331 Tajimi M, 602 Wessler |, 403 Prast H, 183 Satoh H, 674 Takanashi M, 70 Whiting RL, 29 Pritze S, 495 Satoh K, 589 Takikawa R, 133 Wibo M, 698 Probstle T, 596 Sawanobori T, 323 Tamargo J, 645 Wilffert B, 101, 206 Pruneda R, 314 Schmidt E, 302 Tammiso R, 84 Wilhelm D, 206 Schmitz W, 90 Tanaka H, 582 Winder S, 682 Schoeffter P, 137 Q Tanaka Y, 331 Wirth A, 101 Schomig A, 297, 527 TantishaiyakulV , 454 Woditsch |, 240 Quast U, 351 Schomig E, 41, 286, Taylor M, 29 Wolzt M, 302 527 Télémaque S, 505 Woody HA, 471 Schonfeld CL, 520 R Teng CM, 377 Scholz H, 90 Racké K, 143, 403 Schror K, 240 Thyen A, 720 Raiteri M, 275 Schudt C, 682 Torii Y, 564 v Rascher W, 1 Schultz JE, 437 Trendelenburg U, 41, Yamada H, 589 Reither H, 213 Schwietert HR, 206 286, 520, 619 Yanhoutte F, 662 Ricci A, 259 Schworer H, 143 Trout SJ, 623 Yarrow S, 557 Richardt G, 297, 527 Seifert R, 396 Tuomainen P, 412 Yoneyama F, 589 Rosch H, 437 Shams G, 454 Yoshida T, 500 Romstedt KJ, 454 Sillence MN, 442, 449 U Rossodivita A, 259 Simmet T, 495 Uematsu T, 478 Rubino A, 464 Singer EA, 130 Ullrich V, 682 Z Rudel R, 596 Sonnenberg H, 119 Russ H, 286 Spiers WG, 449 Zambotti F, 84 Vv Sponholz F, 114 Zecca L, 84 Starbatty J, 90 Van Maercke YM, 716 Zerkowski HR, 430 S Starke K, 174, 419, 623 Venkataraman BV, 454 Zhang A, 193 Sahim-Erdemli |, 137 Stein B, 90 Verbeke N, 662 Zonta N, 84 Saito H, 564 Sugimoto T, 133 Vereecke J, 574, 662 Zwieten PA van, 107, Salomone S, 698 Sunami A, 323 Veress AT, 119 206 Subject index of volume 344 A adenosine, inotropic effect, cAMP, beta- adrenoceptors, imidazolines, structure- ACE inhibitors, cardiac renin-angiotensin adrenoceptors; heart, dog 70 activity; aorta, rats, human platelets system, captopril, ramiprilat, noradrena- adenosine, protein kinase C, pertussis 454 line; heart, rats 297 toxin, prostaglandin E; human Jurkat adrenoceptors, noradrenaline-ATP co- acetylcholine release, cisplatin, entero- cells 611 transmission; vas deferens, rats, arteries, chromaffine cells, 5-hydroxytryptamine; adenosine deaminase, coronary occlusion, rabbit 532 intestine, guinea-pig 143 adenosine release; heart, rats 544 alpha 2 adrenoceptors, adenosine recep- acetylcholine release, 5-hydroxy- adenosine receptor subtypes, N-ethyl- tors, noradrenaline release; hippocam- tryptamine receptors, neurokinin 3-re- maleimide; bovine cardiac and cerebral pus, rabbit 187 ceptors; ileum, guinea-pig 8 membranes, 639 alpha 2 adrenoceptors, noradrenaline re- acetylcholine release, muscarinic receptor adenosine receptor subtypes, neurotrans- lease, histamine; hypothalamus, cons- subtypes, dopamine release; substantia mission, adenosine; heart, guinea-pig cious rats 183 nigra dendrosomes, rats 275 464 alpha 2-adrenoceptors, Ca-currents; chick acetylcholine release, nerve stimulation, adenosine receptors, noradrenaline rele- sympathetic neurons 382 transmural stimulation; trachea, rats, gu- ase, alpha 2 adrenoceptors; hippocam- alpha 2-adrenoceptors, noradrenaline inea-pig 403 pus, rabbit 187 release, imidazoline receptor, guanidine action potential, inotropism, calcium, phe- adenosine release, adenosine deaminase, derivatives; pulmonary artery, rabbit, nylephrine; heart muscle, rats 574 coronary occlusion; heart, rats 544 630 action potential, muscle contraction, ion adenosine release, inosine release, excita- alpha 2-adrenoceptors, noradrenaline channel blockers; mouse diaphragm, tory amino acids; hippocampal slices, release; chick sympathetic neurons 691 rats 538 130 action potential, pacemaker current, po- adrenaline release, nitric oxide, noradren- alpha-adrenergic receptor subtypes; tassium outward current, YS 035, vera- aline release; haemodynamics, rabbit, human veins 302 pamil derivatives; cardiac Purkinje fi- 720 alpha-adrenoceptors, excitation-contrac- bres, sheep, 653 adrenergic transmission, purinergic trans- tion coupling; portal vein, rats 206 adenosine, adenosine receptor subtypes, mission, ATP, nicotine receptors, amiloride analogues, endothelium-depen- neurotransmission; heart, guinea-pig cotransmission; ileocolic artery, rabbit dent vasorelaxant, Na— Ca-exchange; 464 174 cardiovascular tissues, rats 220 IX anabolic effect, clenbuterol, beta 2- beta-adrenoceptors, adenosine, inotropic cardiac glycosides, palytoxin; ventricular adrenoceptors, growth; heart, skeletal effect, cAMP; heart, dog 70 myocytes, rats 247 muscle, rats 449 beta-adrenoceptors, cAMP, CGP cardiac renin-angiotensin system, capto- angiotensin 2, calcium entry blockers; 20,712 A, inotropic effect; heart, cat 56 pril, ramiprilat, noradrenaline, ACE inhi- aorta, rats, guinea-pig 107 beta-adrenoceptors, denervation-super- bitors; heart, rats 297 angiotensin-converting enzyme, B2-kinin sensitivity; human transplanted heart cardiotonic agents, DPI 201-106, inotro- receptor antagonists, CGMP; human 430 pism, infarction; hemodynamics, dog endothelial cells 126 beta-adrenoceptors, steroid hormones, 478 antiarrhythmic drugs, bisaramil; cardiac antidepressants; pregnancy, ovariec- carrier-mediated outward transport, dopa- cells, guinea-pig, rabbit, dog 323 tomy, rats 437 mine; vas deferens, rats, 619 antiarrhythmic drugs, chronotropic effect; bisaramil, antiarrhythmic drugs; cardiac cGMP, angiotensin-converting enzyme, sino-atrial node, rabbit, 674 cells, guinea-pig, rabbit, dog 323 B2-kinin receptor antagonists; human antiarrhythmic drugs, stereoselectivity, di- blood volume expansion, arginine-vaso- endothelial cells 126 sopyramide; papillary muscle, guinea- pressin, atrial natriuretic peptide; kidney, cGMP, chemoattractant receptors, NO- pig, 662 Brattleboro rats 119 containing compounds, exocytosis; hu- antiarrhythmics, local anaesthetics, so- botulinum-A toxin, cyclic nucleotides, man neutrophils 396 dium channels; human muscle 596 exocytosis, tetanus toxin; chromaffine cGMP, endothelium-derived nitric oxide, antidepressant drugs, NMDA receptors, cells, bovine cell cultures 387 nitrovasodilators; aorta, hamster 345 long-therm potentiation; hippocampu, bradykinin, polymodal receptor, prosta- CGP 20,712 A, inotropic effect, beta- rats 344, 79 glandins; canine testis-spermatic nerve adrenoceptors, cAMP; heart, cat 56 antidepressants, beta-adrenoceptors, ste- 368 chemoattractant receptors, NO-contai- roid hormones; pregnancy, ovariectomy, brain drug concentrations, yohimbine, se- ning compounds, exocytosis, cGMP; rats 437 rum drug concentrations; injections, human neutrophils 396 antidepressants, serotonin, tianeptine; rats 308 chloride transport, opioid peptides, opioid medial septal neurons, rats 568 antagonists, intestinal secretion; colonic anti-ischemic compounds, veratridine, mucosa, guinea-pig 360 calcium uptake, sodium channel; left cholera toxin, G-proteins, 5-HT autore- Cc atria, rats 101 ceptors, pertussis toxin; hippocampus, antipsychotic agents, dopamine receptor Ca-currents, alpha 2-adrenoceptors; chick rats 160 agonists, SDZ 208-911, SDZ 208-912, sympathetic neurons 382 chronotropic effect, antiarrhythmic drugs; terguride; behaviour, rats 263 calcium, neuropeptide Y receptors, G-pro- sino-atrial node, rabbit, 674 aprindine, sodium channels, receptor hy- tein, cAMP; human neuroblastoma cells cigarette smoke, indomethacin, pharma- pothesis, deprotonation; ventricular my- 1 cokinetics; administration routes, rats ocytes, guinea-pig 331 calcium, phenylephrine, action potential, 500 arecoline, receptor classification, musca- inotropism; heart muscle, rats 574 cisapride, renzapride, benzamides, 5-HT rinic receptor, G-proteins; atria, rats 201 calcium channel modulators, 1,4-dihydro- receptors; human right atrium 150 arginine-vasopressin, atrial natriuretic pyridines; ileum, rats, 698 cisplatin, enterochromaffine cells, 5-hy- peptide, blood volume expansion; kid- calcium channels, noradrenaline release, droxytryptamine, acetylcholine release; ney, Brattleboro rats 119 neuropeptide Y, nicotine, protein kinase intestine, guinea-pig 143 ATP, nicotine receptors, cotransmission, C; heart, guinea pig 527 clenbuterol, beta 2-adrenoceptors, adrenergic transmission, purinergic calcium current, potassium current, imi- growth, anabolic effect; heart, skeletal transmission; ileocolic artery, rabbit 174 pramine; cardiac myocytes, guinea-pig, muscle, rats 449 ATP release, noradrenaline release, nico- 645 clenbuterol, beta-adrenoceptor density, tine receptors, cotransmission; vas defe- calcium entry blockers, angiotensin 2; phenylethanolamines, structure-acti- rens, guinea-pig 419 aorta, rats, guinea-pig 107 vity; bovine skeletal muscle 442 atrial natriuretic peptide, blood volume calcium entry blockers, nitrendipine, dihy- coenzyme Q 10, cyanide, K-channel; car- expansion, arginine-vasopressin; kid- dropyridines; porcine heart 488 diac myocytes, guinea-pig 133 ney, Brattleboro rats 119 calcium uptake, sodium channel, anti- competitive antagonism, 5-HT receptor ischemic compounds, veratridine; left antagonists; choroid plexus, pig 137 atria, rats 101 COMT inhibitors, dopamine, MAO inhibi- cAMP, beta-adrenoceptors, adenosine, tors; brain, rats 412 B2-kinin receptor antagonists, cGMP, an- inotropic effect; heart, dog 70 conflict behaviour, GABAergic neuro- giotensin-converting enzyme; human cAMP, calcium, neuropeptide Y receptors, transmission, benzodiazepines; Vogel endothelial cells 126 G-protein; human neuroblastoma cells procedure, rats 314 benzamides, 5-HT receptors, cisapride, 1 coronary occlusion, adenosine release, renzapride; human right atrium 150 cAMP, CGP 20,712 A, inotropic effect, adenosine deaminase; heart, rats 544 benzodiazepine antagonists, nociception, beta-adrenoceptors; heart, cat 56 cotransmission, adrenergic transmission, kappa-opioid receptors, opioid antago- cAMP, E-1020, phosphodiesterase inhibi- purinergic transmission, ATP, nicotine nists, diazepam; tail-flick, rats 84 tor; vascular smooth muscle, rats 602 receptors; ileocolic artery, rabbit 174 benzodiazepines, conflict behaviour, GA- cAMP, phosphodiesterase, inotropic cotransmission, ATP release, noradrenaline BAergic neurotransmission; Vogel pro- effect; human cardiac muscle 90 release, nicotine receptors; vas deferens, cedure, rats 314 cancer chemotherapy, vomiting, 5-HT, guinea-pig 419 beta 2-adrenoceptors, growth, anabolic tropireton; house musk shrew 564 coupling mechanisms, neurokinin receptor effect, clenbuterol; heart, skeletal capsaicin, ion transport; descending co- subtypes, spasmogens; taenia caeci, muscle, rats 449 lon, rats 557 guinea-pig 225 beta-adrenoceptor antagonists, norepi- capsaicin analogs, resiniferatoxin, vanil- CP-96,345, tachykinin receptors, hypo- nephrine spillover rate; hypertensive loid receptors; dorsal root ganglion, rats tension; circulation, dog 471 rats 47 551 cromakalim, minoxidil, K-channel ope- beta-adrenoceptor density, phenyletha- captopril, ramiprilat, noradrenaline, ACE ners, vasorelaxation; aorta, rats 351 nolamines, structure-activity, clenbute- inhibitors, cardiac renin-angiotensin sy- cyanide, K-channel, coenzyme Q 10; car- rol; bovine skeletal muscle 442 stem; heart, rats 297 diac myocytes, guinea-pig 133 X cyclic nucleotides, exocytosis, tetanus to- endothelium-dependent vasodilators, ni- G-proteins, 5-HT autoreceptors, pertussis xin, botulinum-A toxin; chromaffine tric oxide, glyceryltrinitrate; Langen- toxin, cholera toxin; hippocampus, rats cells, bovine cell cultures 387 dorff-heart, rabbit 240 160 cysteinyl-leukotrienes, platelet-activating endothelium-dependent vasorelaxant, growth, anabolic effect, clenbuterol, beta factor, vasoconstriction; porcine pulmo- Na—Ca-exchange, amiloride analo- 2-adrenoceptors; heart, skeletal muscle, nary blood vessels 495 gues; cardiovascular tissues, rats 220 rats 449 endothelium-derived nitric oxide, nitro- guanidine derivatives, alpha 2-adreno- vasodilators, cGMP; aorta, hamster 345 ceptors, noradrenaline release, imi- D energy requirements, glucose deprivation, dazoline receptor; pulmonary artery, hypoxia, noradrenaline; vas deferens, rabbit, 630 denervation-supersensitivity, beta-ad- atrium, rats 286 renoceptors; human transplanted heart energy requirements, potassium, noradre- 430 H naline; vas deferens, atrium, rats 520 deprotonation, aprindine, sodium chan- enterochromaffine cells, 5-hydroxytrypta- histamine, alpha 2 adrenoceptors, norad- nels, receptor hypothesis; ventricular mine, acetylcholine release, cisplatin; renaline release; hypothalamus, cons- myocytes, guinea-pig 331 intestine, guinea-pig 143 cious rats 183 diazepam, benzodiazepine antagonists, epithelial derived relaxant factor, musca- histamine receptors, G-protein; ventricular nociception, kappa-opioid receptors, rinic receptor subtypes; trachea, guinea- myocytes, guinea-pig 582 opioid antagonists; tail-flick, rats 84 pig 29 5-HT, tropireton, cancer chemotherapy, dihydronaphthyridines, dihydropyridines, ethanol, NMDA receptors, noradrenaline vomiting; house musk shrew 564 vascular selectivity, inotropism; porcine release; brain cortex slices, rats 167 5-HT autoreceptors, pertussis toxin, cardiac and vascular smooth muscle ethanol, pertussis toxin, G-proteins; be- cholera toxin, G-proteins; hippocam- asT havioural effects, mice 252 pus, rats 160 dihydropyridines, calcium entry blockers, ethylcholine aziridium, glutamatergic 5-HT receptor antagonists, competitive nitrendipine; porcine heart 488 system, NMDA receptors, neurotoxicity; antagonism; choroid plexus, pig 137 dihydropyridines, vascular selectivity, ino- hippocampus, rats 213 5-HT receptors, cisapride, renzapride, tropism, dihydronaphthyridines; porcine excitation-contraction coupling, alpha- benzamides; human right atrium 150 cardiac and vascular smooth muscle adrenoceptors; portal vein, rats 206 6-hydroxydopamine, free radicals, su- 337 excitatory amino acids, adenosine release, peroxide dismutase; sympathetic dener- 1,4-dihydropyridines, calcium channel inosine release; hippocampal slices, rats vation, dog 36 modulators; ileum, rats, 698 538 5-hydroxytryptamine, acetylcholine re- disopyramide, antiarrhythmic drugs, stere- exocytosis, CGMP, chemoattractant release, cisplatin, enterochromaffine cells; oselectivity; papillary muscle, guinea- ceptors, NO-containing compounds; intestine, guinea-pig 143 pig, 662 human neutrophils 396 5-hydroxytryptamine receptors, neuro- dopamine, carrier-mediated outward exocytosis, tetanus toxin, botulinum-A to- kinin 3-receptors, acetylcholine release; transport; vas deferens, rats, 619 xin, cyclic nucleotides; chromaffine ileum, guinea-pig 8 dopamine, MAO inhibitors, COMT inhibi- cells, bovine cell cultures 387 hypotension, CP-96,345, tachykinin re- tors; brain, rats 412 ceptors; circulation, dog 471 dopamine autoreceptor agonist, U- hypoxia, noradrenaline, energy require- 86170f; rats 509 F ments, glucose deprivation; vas defe- dopamine autoreceptors, dopamine rele- rens, atrium, rats 286 ase; neostriatum, nucleus accumbens, free radicals, superoxide dismutase, 6-hy- rats, 623 droxydopamine; sympathetic denerva- dopamine DA 2 receptors; renal cortex, tion, dog 36 rats 259 imidazoline receptor, guanidine derivati- dopamine receptor agonists, monoamines, ves, alpha 2-adrenoceptors, norad- Parkinson’s disease; chronic treatment, G renaline release; pulmonary artery, rats 281 GABAergic neurotransmission, benzodi- rabbit, 630 dopamine receptor agonists, SDZ 208- azepines, conflict behaviour; Vogel pro- imidazolines, structure-activity, 911, SDZ 208-912, terguride, antipsy- cedure, rats 314 adrenoceptors; aorta, rats, human chotic agents; behaviour, rats 263 GBR 12909, monoaminergic neurotrans- platelets 454 dopamine release, acetylcholine release, mission, dopamine uptake; striatum, imipramine, calcium current, potassium muscarinic receptor subtypes; substan- substantia nigra, rats 16 current; cardiac myocytes, guinea-pig, tia nigra dendrosomes, rats 275 glucose deprivation, hypoxia, noradrena- 645 dopamine release, dopamine auto- line, energy requirements; vas deferens, indomethacin, pharmacokinetics, cigarette receptors; neostriatum, nucleus accum- atrium, rats 286 smoke; administration routes, rats 500 bens, rats, 623 glutamatergic system, NMDA receptors, infarction, cardiotonic agents, DPI 201- dopamine uptake, GBR 12909, monoam- neurotoxicity, ethylcholine aziridium; 106, inotropism; hemodynamics, dog inergic neurotransmission; striatum, hippocampus, rats 213 478 substantia nigra, rats 16 glyceryltrinitrate, endothelium-dependent inosine release, excitatory amino acids, DPI 201-106, inotropism, infarction, car- vasodilators, nitric oxide; Langendorff- adenosine release; hippocampal slices, diotonic agents; hemodynamics, dog 478 heart, rabbit 240 rats 538 G-protein, cAMP, calcium, neuropeptide inotropic effect, beta-adrenoceptors, Y receptors; human neuroblastoma cells cAMP, CGP 20,712 A; heart, cat 56 1 E inotropic effect, cAMP, beta- G-protein, histamine receptors; ventricular adrenoceptors, adenosine; heart, dog E-1020, phosphodiesterase inhibitor, myocytes, guinea-pig 582 70 cAMP; vascular smooth muscle, rats G-proteins, arecoline, receptor classifica- inotropic effect, cAMP, phosphodieste- 602 tion, muscarinic receptor; atria, rats 201 rase; human cardiac muscle 90 endothelin-converting enzyme, phos- G-proteins, ethanol, pertussis toxin; be- inotropism, calcium, phenylephrine, action phoramidon; vas deferens, rats 505 havioural effects, mice 252 potential; heart muscle, rats 574 Xl inotropism, dihydronaphthyridines, dihy- Naja naja atra venom, mast cells, kinin, ve- NO-containing compounds, exocytosis, dropyridines, vascular selectivity; por- nom phospholipase A2; hind-paw, rats cGMP, chemoattractant receptors; hu- cine cardiac and vascular smooth 377 man neutrophils 396 muscle 337 NANC relaxation, serotonin, nitric oxide; noradrenaline, ACE inhibitors, cardiac re- inotropism, infarction, cardiotonic agents, ileum, ileocolonic junction, dog, 716 nin-angiotensin system, captopril, rami- DPI 201-106; hemodynamics, dog 478 nerve stimulation, transmural stimulation, prilat; heart, rats 297 intestinal secretion, chloride transport, acetylcholine release; trachea, rats, gu- noradrenaline, energy requirements, glu- opioid peptides, opioid antagonists; co- inea-pig 403 cose deprivation, hypoxia; vas deferens, lonic mucosa, guinea-pig 360 N-ethylmaleimide, adenosine receptor atrium, rats 286 ion channel blockers, action potential, subtypes; bovine cardiac and cerebral noradrenaline, energy requirements, po- muscle contraction; mouse diaphragm, membranes, 639 tassium; vas deferens, atrium, rats 520 691 neurokinin 3-receptors, acetylcholine re- noradrenaline, stady-state concentration ion transport, capsaicin; descending co- lease, 5-hydroxytryptamine receptors; gradient, uptake 1; vas deferens, rats 41 lon, rats 557 ileum, guinea-pig 8 noradrenaline release, adrenaline release, neurokinin receptor subtypes, spasmo- nitric oxide; haemodynamics, rabbit, K gens, coupling mechanisms; taenia 720 caeci, guinea-pig 225 noradrenaline release, alpha 2 adreno- kappa-opioid receptors, opioid antago- neuropeptide Y, nicotine, protein kinase C, ceptors, adenosine receptors; hippo- nists, diazepam, benzodiazepine anta- calcium channels, noradrenaline release; campus, rabbit 187 gonists, nociception; tail-flick, rats 84 heart, guinea pig 527 noradrenaline release, alpha 2-adreno- K-channel, coenzyme Q 10, cyanide; car- neuropeptide Y receptors, G-protein, ceptors; chick sympathetic neurons 130 diac myocytes, guinea-pig 133 cAMP, calcium; human neuroblastoma noradrenaline release, ethanol, NUDA K-channel openers, vasorelaxation, cro- cells 1 receptors; brain cortex slices, rats 167 makalim, minoxidil; aorta, rats 351 neurotoxicity, ethylcholine aziridium, glu- noradrenaline release, histamine, alpha 2 kinin, venom phospholipase A2, Naja naja tamatergic system, NMDA receptors; adrenoceptors; hypothalamus, cons- atra venom, mast cells; hind-paw, rats hippocampus, rats 213 cious rats 183 377 noradrenaline release, imidazoline recep- neurotransmission, adenosine, adenosine tor, guanidine derivatives, alpha 2-ad- receptor subtypes; heart, guinea-pig L 464 renoceptors; pulmonary artery, rabbit, 630 levodopa, 3-O-methyldopa, pharmacoki- neurotransmitter, lyotropic anions, thio- noradrenaline release, neuropeptide Y, ni- netics; microdialysis, muscle, dog 514 cyanate; vascular smooth muscle, rats cotine, protein kinase C, calcium chan- local anaesthetics, sodium channels, anti- 193 nels; heart, guinea pig 527 arrhythmics; human muscle 596 nicorandil, vasodilating action, 2-nico- noradrenaline release, nicotine receptors, lyotropic anions, thiocyanate, neurotrans- tinamidoethyl acetate, potassium chan- cotransmission, ATP release; vas defe- mitter; vascular smooth muscle, rats nel opener; aorta, rabbit 235 vens, guinea-pig 419 193 nicorandil, vasodilator potencies; coronary noradrenaline-ATP cotransmission, arteries, dog 589 adrenoceptors; vas deferens, rats, ar- 2-nicotinamidoethyl acetate, potassium M teries, rabbit 532 channel opener, nicorandil, vasodilating MAO inhibitors, COMT inhibitors, dopa- action; aorta, rabbit 235 norepinephrine spillover rate, beta- adrenoceptor antagonists; hypertensive mine; brain, rats 412 nicotine, protein kinase C, calcium chan- rats 47 mast cells, kinin, venom phospholipase A2, nels, noradrenaline release, neuropep- Naja naja atra venom; hind-paw, rats tide Y; heart, guinea pig 527 377 nicotine receptors, cotransmission, adre- Oo minoxidil, K-channel openers, vasorelaxa- nergic transmission, purinergic tran- tion, cromakalim; aorta, rats 351 smission, ATP; ileocolic artery, rabbit 3-O-methyldopa, pharmacokinetics, levo- monoaminergic neurotransmission, dopa- 174 dopa; microdialysis, muscle, dog 514 mine uptake, GBR 12909; striatum, sub- nicotine receptors, cotransmission, ATP opioid antagonists, diazepam, benzodi- stantia nigra, rats 16 release, noradrenaline release; vas defe- azepine antagonists, nociception, kap- monoamines, Parkinson's disease, dopa- rens, guinea-pig 419 pa-opioid receptors; tail-flick, rats 84 musmmrceeiancnrteei,p nt roirercac tescrp letaco2ser8sp 1it foairgc,oa ntiGiso-tnps;r ;o tatecrihinras,o ,n riacat rs etcr2oel0ati1-n e, nniitterrinect nrdyoi xpibidlneoe,c, k gedlryisch;ey rdyprlootrprciyinrinitedr iantheee,sa r,t e ncd4ao8ltc8hi eulmi - ooppiicloohoiinlddio c r iapdmneetup atcgitoodrsenaasin,,ss p tosgor,put i,i oinineotdape -isaptoniiintdgaa lg po3ensp6eitc0sirt deset,is o;n i,nc toe-- muscarinic receptor antagonists, spasmo- um-dependent vasodilators; Langen- stinal secretion, chloride transport; co- lytic drugs; common bile duct, guinea- dorff-heart, rabbit 240 lonic mucosa, guinea-pig 360 nitric oxide, NANC relaxation, serotonin; pig 114 ileum, ileocolonic junction, dog, 716 muscarinic receptor subtypes, dopamine P nitric oxide, noradrenaline release, release, acetylcholine release; substantia nigra dendrosomes, rats 275 adrenaline release; haemodynamics, pacemaker current, potassium outward muscarinic receptor subtypes, epithelial rabbit, 720 current, YS 035, verapamil derivatives, derived relaxant factor; trachea, guinea- nitrovasodilators, cGMP, endothelium- action potential; cardiac Purkinje fibres, pig 29 derived nitric oxide; aorta, hamster 345 sheep, 653 muscle contraction, ion channel blockers, NMDA receptors, neurotoxicity, ethylcho- palytoxin, cardiac glycosides; ventricular action potential; mouse diaphragm, 691 line aziridium, glutamatergic system; myocytes, rats 247 hippocampus, rats 213 Parkinson's disease, dopamine receptor NMDA receptors, noradrenaline release, agonists, monoamines; chronic treat- ethanol; brain cortex slices, rats 167 ment, rats 281 Na—Ca-exchange, amiloride analogues, nociception, kappa-opioid receptors, pertussis toxin, cholera toxin, G-proteins, endothelium-dependent vasorelaxant; opioid antagonists, diazepam, benzodi- 5-HT autoreceptors; hippocampus, rats cardiovascular tissues, rats 220 azepine antagonists; tail-flick, rats 84 160 XII pertussis toxin, G-proteins, ethanol; be- receptor classification, muscarinic recep- tetanus toxin, botulinum-A toxin, cyclic havioural effects, mice 252 tor, G-proteins, arecoline; atria, rats 201 nucleotides, exocytosis; chromaffine pertussis toxin, prostaglandin E, adeno- receptor hypothesis, deprotonation, cells, bovine cell cultures 387 sine, protein kinase C; human Jurkat aprindine, sodium channels; ventricular thimerosal, phosphodiesterase inhibitors, cells 611 myocytes, guinea-pig 331 superoxide release; human poly- pharmacokinetics, cigarette smoke, indo- renzapride, benzamides, 5-HT receptors, morphonuclear leukocytes, 682 methacin; administration routes, rats cisapride; human right atrium 150 thiocyanate, neurotransmitter, lyotropic 500 resiniferatoxin, vanilloid receptors, capsai- anions; vascular smooth muscle, rats pharmacokinetics, levodopa, 3-O-methyl- cin analogs; dorsal root ganglion, rats 193 dopa; microdialysis, muscle, dog 514 551 tianeptine, antidepressants, serotonin; phenylephrine, action potential, inotro- medial septal neurons, rats 568 pism, calcium; heart muscle, rats 574 transmural stimulation, acetylcholine rele- Ss phenylethonolamines, structure-activity, ase, nerve stimulation; trachea, rats, gu- clenbuterol, beta-adrenoceptor density; SDZ 208-911, SDZ 208-912, terguride, inea-pig 403 bovine skeletal muscle 442 antipsychotic agents, dopamine recep- tropireton, cancer chemotherapy, vomi- phosphodiesterase, inotropic effect, tor agonists; behaviour, rats 263 ting, 5-HT; house musk shrew 564 cAMP; human cardiac muscle 90 SDZ 208-912, terguride, antipsychotic phosphodiesterase inhibitor, cAMP, agents, dopamine receptor agonists, U E-1020; vascular smooth muscle, rats SDZ 208-911; behaviour, rats 263 602 serotonin, nitric oxide, NANC relaxation; U-86170f, dopamine autoreceptor ago- phosphodiesterase inhibitors, superoxide ileum, ileocolonic junction, dog, 716 nist; rats 509 release, thimerosal; human poly- serotonin, tianeptine, antidepressants; uptake 1, noradrenaline, stady-state morphonuclear leukocytes, 682 medial septal neurons, rats 568 concentration gradient; vas deferens, phosphoramidon, endothelin-converting serum drug concentrations, brain drug rats 41 enzyme; vas deferens, rats 505 concentrations, yohimbine; injections, platelet-activating factor, vasoconstric- rats 308 Vv tion, cysteinyl-leukotrienes; porcine sodium channel, anti-ischemic com- vanilloid receptors, capsaicin analogs, re- pulmonary blood vessels 495 pounds, veratridine, calcium uptake; left siniferatoxin; dorsal root ganglion, rats polymodal receptor, prostaglandins, bra- atria, rats 101 551 dykinin; canine testis-spermatic nerve sodium channels, antiarrhythmics, local vascular selectivity, inotropism, dihydro- 368 anaesthetics; human muscle 596 naphthyridines, dihydropyridines; por- potassium, noradrenaline, energy require- sodium channels, receptor hypothesis, de- cine cardiac and vascular smooth ments; vas deferens, atrium, rats 520 protonation, aprindine; ventricular my- muscle 337 potassium channel opener, nicorandil, va- ocytes, guinea-pig 331 vasoconstriction, cysteinyl-leukotrienes, sodilating action, 2-nicotinamidoethyl spasmogens, coupling mechanisms, neu- platelet-activating factor; porcine pul- acetate; aorta, rabbit 235 rokinin receptor subtypes; taenia caeci, monary blood vessels 495 potassium channel openers, vaso- guinea-pig 225 vasodilating action, 2-nicotinamidoethyl relaxants; vascular muscle, rats, 706 spasmolytic drugs, muscarinic receptor acetate, potassium channel opener, ni- potassium current, imipramine, calcium antagonists; common bile duct, guinea- corandil; aorta, rabbit 235 current; cardiac myocytes, guinea-pig, pig 114 vasodilator potencies, nicorandil; coronary 645 stady-state concentration gradient, uptake arteries, dog 589 potassium outward current, YS 035, vera- 1, noradrenaline; vas deferens, rats 41 vasorelaxants, potassium channel ope- pamil derivatives, action potential, pace- stereose'=>stivity, disopyramide, antiarr- ners; vascular muscle, rats, 706 maker current; cardiac Purkinje fibres, hythmic drugs; papillary muscle, gu- vasorelaxation, cromakalim, minoxidil, K- sheep, 653 inea-pig, 662 channel openers; aorta, rats 351 prostaglandin E, adenosine, protein kinase steroid hormones, antidepressants, beta- venom phospholipase A2, Naja naja atra C, pertussis toxin; human Jurkat cells adrenoceptors; pregnancy, ovariectomy, venom, mast cells, kinin; hind-paw, rats 611 rats 437 377 prostaglandins, bradykinin, polymodal re- structure-activity, adrenoceptors, imida- verapamil derivatives, action potential, pa- ceptor; canine testis-spermatic nerve zolines; aorta, rats, human platelets 454 cemaker current, potassium outward 368 structure-activity, clenbuterol, beta- current, YS 035; cardiac Purkinje fibres, protein kinase C, calcium channels, nor- adrenoceptor density, phenylethanola- sheep, 653 adrenaline release, neuropeptide Y, ni- mines; bovine skeletal muscle 442 veratridine, calcium uptake, sodium chan- cotine; heart, guinea pig 527 superoxide dismutase, 6-hydroxy- nel, anti-ischemic compounds; left atria, protein kinase C, pertussis toxin, prosta- dopamine, free radicals; sympathetic rats 101 glandin E, adenosine; human Jurkat denervation, dog 36 vomiting, 5-HT, tropireton, cancer chemo- cells 611 superoxide release, thimerosal, phospho- therapy; house musk shrew 564 purinergic transmission, ATP, nicotine diesterase inhibitors; human poly- receptors, cotransmission, adrenergic morphonuclear leukocytes, 682 transmission; ileocolic artery, rabbit 174 Y T yohimbine, serum drug concentrations, brain drug concentrations; injections, R tachykinin receptors, hypotension, CP- rats 308 96,345; circulation, dog 471 YS 035, verapamil derivatives, action ramiprilat, noradrenaline, ACE inhibitors, terguride, antipsychotic agents, dopamine potential, pacemaker current, potassium cardiac renin-angiotensin system, cap- receptor agonists, SDZ 208-911, SDZ outward current; cardiac Purkinje fibres, topril; heart, rats 297 208-912; behaviour, rats 263 sheep, 653