Mount Sinai Journal of Medicine

2007·4.8 MB·English

by  Mount Sinai Hospital (New York, N.Y.)

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1 I I
MOUNT
SINAI JOURNAL OF MEDICINE
A JOURNAL OF TRANS LATIONAL AND PERSONALIZED MEDICINE
CONTENTS
VOL NO
74, 1
1 Old,YetEverNew
PennyA.Asbell
2 TheJournahARetrospective
BarbaraJ.NissandArthurH.Aufses
7 TranslationalExperimentalTherapeutics:TheTranslationofLaboratory-BasedDiscoveryintoDisease-Related
Therapy
KarlKieburtzandC. WarrenOlanow
15 Foundations,PromisesandUncertaintiesofPersonalizedMedicine
ErwinP.Bottinger
22 TheRoleofthePathologistinTranslationalandPersonalizedMedicine
DanielP.Perl
27 NetworkAnalysisofFDAApprovedDrugsandtheirTargets
AviMa'ayan, SherryL.Jenkins, JosephGoldfarbandRaviIyengar
33 HandwashingandInfectionControl
FredRosner
36 JoboftheBible:LeprosyorScabies?
ThierryAppelboom,ElieCoganandJeanKlastersky
40 ApparentMineralocorticoidExcessManifestedinanElderlyPatientwithLiypothyroidism
MariaI.New
OntheCover:AnetworkmapoftheFDAapproveddrugsandtheirproteintargetsinhumancells.Theimagerepresentsabipartitenetworkof
interactionsbetweendrugsandtheirhumangeneproducts.TheinformationabouttheseinteractionswasobtainedfromtheFDAElectronicOrange
Book(EOB)andDrugBank.Graynodesrepresentdrugsandyellownodestheirknownhumanproteintargets(EntrezGenenames).Thenetwork
contains one large cluster that is enriched in drugs that target G protein coupled receptors. A high-resolution image can be viewed at
www.mssm.edu/labs/iyengar.
I \ 8 O 7
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S 2 OO 7
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MOUNT
SINAI JOURNAL OF MEDICINE
A JOURNAL OF TRANSLATIONAL AND PERSONALIZED MEDICINE
Editor Editorial Board
PennyA.Asbell StuartAaronson
ErwinBottinger
DeputyEditors MarkR. Chassin
DennisCharney
EricHollander
RaviIyengar
IVlclllaINcW
PaulKlotman
C.WarrenOlanow MaryKlotman
FredLublin
ThomasG. McGinn
SusanMorgello
HughSampson
MarySano
FredSuchy
AnthonySquire
SavioWoo
MountSinaiSchoolofMedicine
NewYork, NewYork.
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MOUNT
SINAI JOURNAL OF MEDICINE
A jOURNAL OF TRANS LAT1ONAL AND PERSONALIZED MEDICINE
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