Metabolic Syndrome and Diabetes: Medical and Surgical Management

264 Pages·2016·6.449 MB·English

by  Marina Kurian, Bruce M. Wolfe, Sayeed Ikramuddin (eds.)

Metabolic
Syndrome and
Diabetes
Medical and Surgical
Management
Marina Kurian
Bruce M. Wolfe
Sayeed Ikramuddin
Editors
123
Metabolic Syndrome and Diabetes

Marina Kurian (cid:129) Bruce M. Wolfe
Sayeed Ikramuddin
Editors
Metabolic Syndrome
and Diabetes
Medical and Surgical Management
Editors
Marina Kurian Bruce M. Wolfe
Department of Surgery Department of Surgery
NYU School of Medicine Oregon Health and Science University
New York , NY , USA Portland , OR , USA
Sayeed Ikramuddin
Department of Surgery
University of Minnesota
Minneapolis , MN , USA
ISBN 978-1-4939-3219-1 ISBN 978-1-4939-3220-7 (eBook)
DOI 10.1007/978-1-4939-3220-7
Library of Congress Control Number: 2015955740
Springer New York Heidelberg Dordrecht London
© Springer Science+Business Media New York 2016
T his work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of
the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation,
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now known or hereafter developed.
T he use of general descriptive names, registered names, trademarks, service marks, etc. in this publication
does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant
protective laws and regulations and therefore free for general use.
T he publisher, the authors and the editors are safe to assume that the advice and information in this book
are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the
editors give a warranty, express or implied, with respect to the material contained herein or for any errors
or omissions that may have been made.
Printed on acid-free paper
S pringer Science+Business Media LLC New York is part of Springer Science+Business Media
(www.springer.com)
Pref ace
A few years ago, I had the great pleasure of chairing a course with Dr. Bruce Wolfe
on Metabolic Syndrome and its management. This was a well-attended course that
provided clarity on what we as medical professionals are trying to achieve in this
patient population. My coeditors, Dr. Sayeed Ikrammudin and Dr. Bruce Wolfe,
presented the nascent biology of the disease and the cause of infl ammation with
such aplomb that the attendees were truly riveted by the material. There were sev-
eral other presentations delivered by experts in bariatric surgery on the outcomes of
weight loss surgery in metabolic syndrome. At the close of the course, Bruce and
I were approached by Richard Hruska, editor at Springer, about creating a textbook
based on the course.
As we committed to the book, I wanted Sayeed to be a part of the project. For
those of you who don’t know either Bruce or Sayeed, they are two of the most
thoughtful and consummate scientists I know. Both have spent considerable time
delving into disease etiology and incretin effect on diabetes and metabolic syn-
drome. With their help, we created a textbook that is a resource for all medical
professionals and gives the most up-to-date research on the topic. This is a textbook
that is comprehensive in its focus on metabolic syndrome with medical and surgical
perspectives from experts in the fi eld. This book is a resource for everyone involved
in the care of the patient with diabetes and/or metabolic syndrome. Sayeed, Bruce,
and I are proud of the fi nished product, and we know you, the reader, will appreciate
the clarity this book provides.
New York, NY, USA Marina Kurian, M.D., F.A.C.S., F.A.S.M.B.S.
v

Contents
1 Definition, History, and Management of the Metabolic Syndrome
and Management Gaps ........................................................................... 1
Josep Vidal and Amanda Jiménez
2 Extending Current Definitions of the Metabolic Syndrome ............... 19
Karunakaran Indulekha, Ranjit Unnikrishnan , and V. Mohan
Part I Understanding Diabetes Mellitus
3 Understanding Diabetes Mellitus: Pathophysiology ............................ 33
Meera Shah and Adrian Vella
4 Medical Approaches to Weight-Centric Management
of Obese Patients with Type 2 Diabetes ................................................ 47
Donna H. Ryan
5 Adipocyte Dysfunction, Inflammation, and Insulin
Resistance in Obesity .............................................................................. 61
Cyrus Jahansouz
6 Bile Acids, the Microbiome and Metabolic Disease-Implications
for Surgery ............................................................................................... 81
Cyrus Jahansouz
7 The History of Metabolic Surgery ......................................................... 91
Walter Pories
Part II What We Know About Mechanisms of Weight Loss Surgery
8 Obesity and Cancer ................................................................................. 111
Robert W. O’Rourke
9 Effect of Bariatric Surgery on Incretin Function ................................ 125
Blandine Laferrère
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viii Contents
10 Effect of Bariatric Surgery on Insulin Secretion .................................. 141
Kim T. Nguyen and Judith Korner
Part III Surgery for Diabetes and the Metabolic Syndrome
11 The Metabolic Effects of Laparoscopic Adjustable
Gastric Banding ...................................................................................... 159
Marina Kurian and John Loy
12 Sleeve Gastrectomy ................................................................................. 167
Gregg H. J ossart
13 Roux-en-Y Gastric Bypass ..................................................................... 175
Eric J. DeMaria and Saba Ansari
14 Biliopancreatic Diversion with Duodenal Switch ................................. 187
Mustafa Hussain and Vivek N. Prachand
15 Ileal Interposition with Sleeve Gastrectomy for the Treatment
of Type 2 Diabetes ................................................................................... 197
Aureo L. DePaula , Carolina C. L. DePaula , and Surendra Ugale
16 Balancing Complications and Metabolic Benefit ................................. 207
Elias Chousleb , Soni Chousleb , and Natan Zundel
Part IV Future Treatments
17 Neural Modulation in the Treatment of Obesity .................................. 221
Michael G. Sarr and Todd A. Kellogg
18 Endoscopic Duodenal–Jejunal Bypass: Endobarrier .......................... 227
Manoel Galvao Neto and Josemberg Marins Campos
19 Intragastric Balloon ................................................................................ 237
Nicole Pena Sahdala
Index ................................................................................................................. 265
Contributors
Saba Ansari , M.D. Department of Surgery, Virginia Commonwealth University,
Richmond, VA, USA
Josemberg Marins Campos , M.D. Pernambuco Federal University , Recife , Brazil
Soni Chousleb , M.D. FIU Herbert Wertheim College of Medicine, North Miami
Beach, FL, USA
Elias Chousleb , M.D., F.A.C.S. JMG Specialty Physicians , North Miami Beach ,
FL , USA
Eric J. DeMaria , M.D. Bon Secours Maryview Medical Center , Portsmouth , VA, USA
Carolina C. L. DePaula , M.D. Hospital de Especialidades , Sao Paulo , Brazil
Aureo L. DePaula , M.D., Ph.D. Hospital de Especialidades , Sao Paulo , Brazil
Mustafa Hussain , M.D. University of Chicago , Chicago , IL , USA
Karunakaran Indulekha, Ph.D. Who Collaborating Centre, Non-Communicable
Disease Prevention and Control and IDF Centre of Education, Dr. Mohan’s Diabetes
Specialities Centre & Madras Diabetes , Chennai , India
Cyrus Jahansouz, M.D. Department of Surgery , University of Minnesota ,
Minneapolis , MN , USA
Amanda Jiménez, M.D. Obesity Unit, Endocrinology and Diabetes Department ,
Hospital Clínic Universitari , Barcelona , Spain
Gregg H. Jossart , M.D., F.A.C.S. California Pacifi c Medical Center , San Francisco ,
CA , USA
Todd A. Kellogg , M.D. Department of Surgery , Mayo Clinic , Rochester , MN , USA
Judith Korner , M.D., Ph.D. Division of Endocrinology, Department of Medicine ,
Columbia University Medical Center , New York , NY , USA
Marina Kurian , M.D., F.A.C.S., F.A.S.M.B.S. Department of Surgery , NYU
School of Medicine , New York , NY , USA
ix