Lectures in Obstetrics, Gynaecology and Women’s Health Gab Kovacs Paula Briggs 123 Lectures in Obstetrics, Gynaecology and Women’s Health Gab Kovacs (cid:129) P aula Briggs Lectures in Obstetrics, Gynaecology and Women’s Health Gab Kovacs Paula Briggs Department of Obstetrics Sexual and Reproductive Health and Gynaecology Southport and Ormskirk Hospital Monash University Southport Clayton , Victoria UK Australia ISBN 978-3-319-14862-5 ISBN 978-3-319-14863-2 (eBook) DOI 10.1007/978-3-319-14863-2 Library of Congress Control Number: 2015940566 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. 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Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com) The 30 topics you need to know to pass O & G Acknowledgements We would like to thank Naomi Ockersz and Josh Wright from Sonoa Health for drawing the illustrations, Dr. Agnes Bankier for helping with genetics, and Dr. John Campbell for checking the Obstetrics chapters. I would also like to thank and pay tribute to Professor William A. W. Walters, whose enthusiasm for teaching launched me on an academic career. Clayton, Victoria, Australia Gab Kovacs vii Contents Part I Introduction 1 Basic Physiology: The Menstrual Cycle. . . . . . . . . . . . . . . . . . . 3 Hormonal Control of Ovulation. . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Development of the Graafi an Follicle . . . . . . . . . . . . . . . . . . . . . . 3 The Effect of Oestrogen and Progesterone on the Endometrium. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Ovulation of the Follicle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 The Corpus Luteum and Pregnancy. . . . . . . . . . . . . . . . . . . . . . . . 4 Basal Body Temperature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Cervical Mucous Changes and the Basis of the Billings Method of Natural Family Planning . . . . . . . . . . . 5 Fertilisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Early Embryonic Development and Implantation. . . . . . . . . . . . . 7 2 Basic Embryology: The Development of the Foetus. . . . . . . . . 9 3 Basic Genetics for the Obstetrician . . . . . . . . . . . . . . . . . . . . . . 11 Chromosome Structure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Genetic Abnormalities. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Single Gene Defects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Aneuploidy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Multifactorial Congenital Abnormalities. . . . . . . . . . . . . . . . . . . . 14 Antenatal Screening for Chromosmal Problems (Prenatal Diagnosis –PND). . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Preimplantation Genetic Diagnosis. . . . . . . . . . . . . . . . . . . . . . 15 4 The Gynaecological History and Examination . . . . . . . . . . . . . 17 History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Menstrual History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Contraceptive History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Obstetric History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Cervical Cytology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 General Medical History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Presenting Problem. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 The Gynaecological Examination . . . . . . . . . . . . . . . . . . . . . . . . . 18 Abdominal Examination . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 Speculum Examination . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 ix