Journal of Neuropathology and Experimental Neurology 1996: Vol 55 Table of Contents

11 Pages·1996·3 MB·English

JOURNAL OF
NEGROPATHOLOGY
AND EXPERIMENTAL
NEGROLOGY
Volume 55
1996
ALLEN PRESS, INC.
JOURNAL OF
NEGROPATHOLOGY
AND EXPERIMENTAL
NEGROLOGY
Official Journal of the American Association of Neuropathologists, Inc.
EDITOR-IN-CHIEF
MICHAEL NOEL HART, MD
FORMER EDITORS
1942-49 GEORGE B. HASSIN, MD 1961-62 ARTHUR WEIL, MD
1950-52 JOSEPH H. GLOBUS, MD 1963-81 ABNER WOLF, MD
1953-60 ARMANDO FERRARO, MD 1981-91 JOHN MOOSSY, MD
& ARTHUR WEIL, MD
MANAGING EDITOR
MICHELLE KURZYNSKI
Editorial Board
DOUGLAS C. ANTHONY, MD, PhD JAMES E. GOLDMAN, MD, PhD
GARY L. BAUMBACH, MD FRANCOISE GRAY, MD, PhD
CATHERINE BERGERON, MD CLAUDIA M. GRECO, MD
CARL P. BOESEL, MD CHRISTINE HULETTE, MD
THOMAS W. BOULDIN, MD C. DAVID JAMES, MD, PhD
JANET M. BRUNER, MD LAUREN A. LANGFORD, MD
GERALD A. CAMPBELL, MD, PhD EHUD LAVI, MD
VENKAT R. CHALLA, MD JOHN M. LEE, MD
ARTHUR C. CLARK, MD BRIAN W. LITTLE, MD, PhD
MARK COHEN, MD DAVID N. LOUIS, MD
V. PETER COLLINS, MD ANDREW P. MIZISIN, PhD
STEPHEN COONS, MD WILLEMINA MOLENAAR, MD, PhD
BARBARA J. CRAIN, MD, PhD ROBERT E. MRAK, MD, PhD
ANNE CROSS, MD SEAN MURPHY, PhD
JAMES DOLLAR, MD JOSEPH E. PARISI, MD
ANDREW G. ENGEL, MD CAROL K. PETITO, MD
ALFONSO ESCOBAR, MD C. HARKER RHODES, MD
ZSUZSANNA FABRY, PhD LUCY B. RORKE, MD
JONATHAN FRATKIN, MD RAYMOND SOBEL, MD
ROBERT FUJINAMI, PhD KAREN M. WEIDENHEIM, MD
CANDECE L. GLADSON, MD WILLIAM O. WHETSELL, JR, MD
JEFFREY A. GOLDEN, MD CHARLES L. WHITE, MD
The JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (ISSN 0022-3069) is pub-
lished monthly by the American Association of Neuropathologists, Inc., 1041 New Hampshire Street, Law-
rence, KS 66044. Subscription rates are $95.00 per year for U.S. individuals and $115.00 for U.S. institutions.
Non-U.S. rates are $105.00 and $115.00 for individuals and $125.00 and $135.00 for institutions. Periodicals
postage paid at Lawrence, KS. POSTMASTER: Send address changes to P.O. Box 1897, Lawrence, KS
66044-8897.
Copyright © 1996 by the American Association of Neuropathologists, Inc.
Contents of Volume LV
NUMBER 1, JANUARY, 1996
Current Concepts of Excitotoxicity. WILLIAM O. WHETSELL Jr., MD
Intracerebral Targets and Immunomodulation of Murine Listeria monocytogenes Meningoencephalitis. D.
SCHLUTER, S. CHAHOUD, H. LASSMANN, A. SCHUMANN, H. Hor, AND M. DECKERT-SCHLUTER, Mannheim and Bonn,
Germany and Wien, Austria
Alterations in Nitrogen Monoxide—Synthesizing Cortical Neurons in Amyotrophic Lateral Sclerosis with Dementia.
RopDRIGO O. KULJIS AND ROBERT L. SCHELPER, Miami, Florida and Iowa City, Iowa
H,O, and Nitric Oxide—mediated Oxidative Stress Induce Apoptosis in Rat Skeletal Muscle Myoblasts. MARTIN
STANGEL, MD, BMEDSci, Uwe K. ZeTTL, MD, EILHARD Mix, MD, PHD, JURGEN ZIELASEK, MD, KLaus V. Toyka,
MD, HANS-PETER HARTUNG, MD, AND RALF GOLD, MD, Wiirzburg and Rostock, Germany
Neocortical Lewy Body Counts Correlate with Dementia in the Lewy Body Variant of Alzheimer’s Disease. WIL-
LIAM SAMUEL, MD, PHD, DouGLAs GALASKO, MD, ELIEZER MASLIAH, MD, AND LAWRENCE A. HANSEN, MD, San
Diego, California
Neuropathologic Overlap of Progressive Supranuclear Palsy, Pick’s Disease and Corticobasal Degeneration. MEL
B. FeANy, MD, PHD, LINDA A. MATTIACE, PHD, AND DENNIS W. Dickson, MD, Bronx, New York
Cytoskeletal Derangements of Cortical Neuronal Processes Three Hours After Traumatic Brain Injury in Rats:
An Immunofluorescence Study. R. M. PosMANTuR, BA, A. KAMPFL, MD, S. J. Liu, MD, K. Heck, MD, W. C.
TAFT, PHD, G. L. CLIFTON, MD, AND R. L. HAYEs, PHD, Houston, Texas
Detection of Compiex Genetic Alterations in Human Glioblastoma Multiforme Using Comparative Genomic Hy-
bridization. JURGEN SCHLEGEL, MD, HARRY SCHERTHAN, PHD, NORBERT ARENS, PHD, GaBI STUMM, MD, AND
MARIKA KIESSLING, MD, Marburg, Kaiserslautern, and Heidelberg, Germany
Transfection of an Invasive Human Astrocytoma Cell Line with a TIMP-1 cDNA: Modulation of Astrocytoma
Invasive Potential. KAZUHITO MATSUZAWA, KOUZOU FUKUYAMA, SHERRI LYNN HUBBARD, PETER B. DiRKS, AND JAMES
T. RUTKA, Ontario, Canada
Validity and Reliability of the Preliminary NINDS Neuropathologic Criteria for Progressive Supranuclear Palsy
and Related Disorders. I. LirvAN, MD, J. J. HAuw, MD, J. J. BARTKO, PHD, P. L. LANTos, MD, S. E. DANIEL,
MD, D. S. HoroupiAn, MD, A. McKEE, MD, D. Dickson, MD, C. BANCHER, MD, M. TABATON, MD, K. JELLINGER,
MD, AND D. W. ANDERSON, PHD, Bethesda, Maryland; Paris, France; London, UK; Stanford, California; Boston,
Massachusetts; Bronx, New York; Vienna, Austria; and Cleveland, Ohio
Brain Myelinolysis Following Hypernatremia in Rats. ALAIN SOUPART, MD, RAYMOND PENNINCKX, BSC, BERNARD
NamIaAs, MD, ALAIN STENUIT, MD, OLIVIER PERIER, MD, PHD, AND Guy DECAUX, MD, PHD, Brussels, Belgium ...
Developmental Changes in [*H]Lysergic Acid Diethylamide ((7H]LSD) Binding to Serotonin Receptors in the
Human Brainstem. Natasa ZEC, MD, PHD, JAMES J. FILIANO, MD, ASHOK PANIGRAHY, BA, W. Frost WHITE,
PHD, AND HANNAH C. KINNEY, MD, Boston, Massachusetts and Groton, Connecticut
In Memoriam
Harry M. Zimmerman, MD (1901-1995) (AsAo HIRANO, MD)
Presentation of the Meritorious Award of the American Association of Neuropathologists (CEpRIc S. RAINE)
Letter to the Editor
Qualitative and Quantitative Differences in Senile Plaque Dystrophic Neurites of Alzheimer’s Disease and Normal
Aged Brain. William I. Rosenblum, MD. REpLy: DAvip G. Munoz, MD, FRCPC
NUMBER 2, FEBRUARY, 1996
Malformations of the Brain. MARGARET G. NORMAN, MD, Vancouver, British Columbia
Accumulation of Wild-Type p53 Protein in Progressive Multifocal Leukoencephalopathy: A Flow Cytometry and
DNA Sequencing Study. AURELIO ARIZA, MD, CLAUDIA VON UEXKULL-GULDEBAND, PHD, José L. MATE, MD, Marc
IsAMAT, PHD, CARME ARACIL, BS, FéLix E Cruz-SANCHEZ, MD, AND JosE J. Navas-PALacios, MD, Barcelona,
Host Nerve Fibers That Regenerate and Reside Long-term in a Rejected Nerve Allograft Are Not Protected by
Permeability Barriers. NaBiL A. AZZAM, PHD, ANDREW A. ZALEWSKI, MD, AND RITA N. Azzam, Bethesda, Mary-
Specific Pathological Tau Protein Variants Characterize Pick’s Disease. ANDRE DELACOURTE, PHD, YVES ROBITAILLE,
MD, FCAP, NICOLAS SERGEANT, MSc, Luc Bug&e, PHD, PATRICK R. Hor, MD, ANNICK WaTTEZ, BSC, ANDREE
LAROCHE-CHOLETTE, MD, FRCP (C), JEAN MATHIEU, MD, FRCP (C), PIERRE CHAGNON, PHD, AND DENIS GAUVREAU,
PHD, Lille, France, Montreal, Quebec, and New York, New York
Experimental Brain Glioma: Growth Arrest and Destruction By a Blood-Group-Related Tetrasaccharide. M.
NiETO-SAMPEDRO, PHD, C. BAILON, A. FERNANDEZ-MAYORALAS, PHD, M. MARTIN-LOMAS, PHD, B. MELLSTROM, PHD,
AND J. R. NARANJO, PHD, Madrid, Spain
Distribution of Heterotopic Neurons in Normal Hemispheric White Matter: A Morphometric Analysis. AMyN M.
RosIANI, MD, PHD, JACQUELINE A. EMERY, MD, KEVIN J. ANDERSON, PHD, AND JAMES K. MAssEy, ME, Gainesville,
Florida
Anti-GM1 Ganglioside Antibodies Cloned from Autoimmune Neuropathy Patients Show Diverse Binding Patterns
in the Rodent Nervous System. G. M. O’HANLON, PHD, G. J. PATTERSON, PHD, G. WILSON, BSc, D. DoyYLe, MD,
P. McHaropig, MSc, AND H. J. WILLISON, MB, BS, PHD, Glasgow, Scotland
Extrusion of Corpora Amylacea from the Marginal Glia at the Vestibular Root Entry Zone. ANDREA SBARBATI,
Marco CARNER, VITTORIO COLLETTI, AND FRANCESCO OSCULATI, Verona and Ancona, Italy
Crosslinking of Apolipoprotein E by Products of Lipid Peroxidation. THoMaAs J. MonTINE, MD, PHD, Davip Y.
HUANG, WILLIAM M. VALENTINE, DVM, PHD, VENKATARAMAN AMARNATH, PHD, ANN SAUNDERS, PHD, KARL H.
WEISGRABER, PHD, DoYLE G. GRAHAM, MD, PHD, AND WARREN J. STRITTMATTER, MD, Durham, North Carolina
and San Francisco, California
Motor Neuron Degeneration Induced by Excitotoxin Agonists Has Features in Common with those Seen in the
SOD-1 Transgenic Mouse Model of Amyotrophic Lateral Sclerosis. CHRYSANTHY IKONOMIDOU, MD, YUE QIN
Qin, MD, JOANN LABRUYERE, AND JOHN W. OLNEY, MD, St. Louis, Missouri
Regulation by Cytokines and Lipopolysaccharide of E-selectin Expression by Human Brain Microvessel Endo-
thelial Cells in Primary Culture. DONALD WoNG, PHD AND KATERINA DorOVINI-ZIS, MD, Vancouver, British
Columbia
Distribution of Integrin-like Immunoreactivity on Primate Brain Microvasculature. HANS-PETER HARING, MD,
PEARL AKAMINE, BS, ROLF HABERMANN, PHD, JAMES A. KOZIOL, PHD, GREGORY J. DEL Zoppo, MD, La Jolla,
California
Activation of Protein Kinase C Induces Neurofilament Fragmentation, Hyperphosphorylation of Perikaryal Neu-
rofilaments and Proximal Dendritic Swellings in Cultured Motor Neurons. M. M. DoroupcHI, DVM AND
H. D. DURHAM, PHD
Book Reviews
Principles and Practice of Neuropathology. James S. Nelson, Joseph E. Parisi, and Sydney S. Schochet, Jr., Eds.
(E Curtis DOHAN, JR., MD)
Eye, Brain, and Vision. David Hubel. (JONATHAN D. FRATKIN, MD)
NUMBER 3, MARCH, 1996
Neuropathology of Parkinson’s Disease. Lysia S. FoRNO, MD, Palo Alto, CA
Correlation of Astrocytic $1006 Expression with Dystrophic Neurites in Amyloid Plaques of Alzheimer’s Disease.
ROBERT E. Mrak, MD, PHD, Jin G. SHENG, MD, AND W. SUE T. GRIFFIN, PHD, Little Rock, Arkansas and Shanghai,
Apoptosis and Expression of Bcl-2 after Compression Trauma to Rat Spinal Cord. Gui Lin Li, MD, GREGER BRODIN,
BSci, MOHAMMAD FAROOQUE, MBBS, KEIKO FuNA, MD, PHD, ANDERS HOLTZ, MD, PHD, WEN LIANG WANG, MD,
AND YNGVE OLSSON, MD, PHD, Uppsala, Sweden
Ultrastructural Distribution of PMP22 in Charcot-Marie-Tooth Disease Type 1A. CaroL Haney, BS, G. JACKSON
SNIPES, MD, PHD, Eric M. SHOOTER, PHD, UELI SUTER, PHD, CARLOS GARCIA, MD, JOHN W. GRIFFIN, MD, AND
Bruce D. Trapp, PHD, Cleveland, Ohio, Stanford, California, Zurich, Switzerland, New Orleans, Louisiana, and
Baltimore, Maryland
Matrix Metalloproteinases in the Normal Human Central Nervous System, Microglial Nodules, and Multiple
Sclerosis Lesions. ATSUKO MAEDA, MD, AND RAYMOND A. SOBEL, MD, Palo Alto and Stanford, California
Natural Killer Cells and Macrophages in Immature Denervated Rat Muscles. HENNING SCHMALBRUCH,
MD, Copenhagen, Denmark
Human Cortex Development: Estimates of Neuronal Numbers Indicate Major Loss Late During Gestation. THEODORE
RABINOWICZ, MD, GABRIELLE M DE CouRTEN-Myers, MD, JEAN MCDONALD-CoMBER PETETOT, BS, GUOHUA Xi, MD,
AND EMILY DE LOS REYES, MD, Lausanne, Switzerland, Cincinnati, Ohio, and Charleston, West Virginia
Preservation of Calretinin-immunoreactive Neurons in the Hippocampus of Epilepsy Patients with Ammon’s Horn
Sclerosis. INGMAR BLUMCKE, MD, HEINZ BECK, MD, RoBErRT NitscH, MD, CHRISTINA EICKHOFF, BJORN SCHEFFLER,
Marco R. CELIO, MD, JOHANNES SCHRAMM, MD, CHRISTIAN E. ELGER, MD, HELMUT K. WoLF, MD, AND OTMAR
D. WIESTLER, MD, Bonn and Berlin, Germany and Fribourg, Switzeriand
Cytokine Expression Profile in Idiopathic Inflammatory Myopathies. Dominique S. Tews, MD AND HANs H. GOEBEL,
MD, Mainz, Germany
Ependymal Changes in Sudden Infant Death Syndrome. Joaquin LUCENA, MD AND FELIx EF Cruz-SANCHEZ, MD,
PHD, MRCPath, Barcelona, Spain
Follow-up Study on Histogenesis of Microcephaly Associated with Ectopic Gray Matter Induced by Prenatal
y-irradiation in the Mouse. XUE-ZHI SUN, MINORU INOUYE, YOSHIKO TAKAGISHI, SHIZU HAYASAKA, AND HIDEKI
YAMAMURA, Nagoya, Japan
Microglia Are Not Exclusively Associated with Plaque-rich Regions of the Dentate Gyrus in Alzheimer’s Disease.
MATTHEW T. ROE, MD, DEBORAH V. DAWSON, PHD, CHRISTINE M. HULETTE, MD, GILLIAN EINSTEIN, PHD, AND
BARBARA J. CRAIN, MD, PHD, Durham, North Carolina, Cleveland, Ohio, and Baltimore, Maryland
Neurons of the Human Frontal Cortex Display Apolipoprotein E Immunoreactivity: Implications for Alzheimer’s
Disease. RANDY E. ME7TzGir, Mary Jo LADu, PHD, Jia B. PAN, MD, Goprrey S. Getz, MD, PHD, DONALD E.
FRAIL, PHD, AND MICHAEL T. FALDUTO, PHD, Abbott Park and Chicago, IL
Immunohistochemical Localization of Extracellular Matrix Proteins in Cerebral Vessels in Chronic Hypertension.
Sukrit!1 NAG, MD, PHD, FRCPC, Toronto, Ontario, Canada
NUMBER 4, APRIL, 1996
Heat Shock Proteins and Multiple Sclerosis: A Review. CELIA E BROSNAN, PHD, Luca BatrTisTINI, MD, YAN-LING
Gao, MD, Cepric S. RAINE, PHD, DSc, AND DENNIS A. AQUINO, PHD, Bronx, New York and Waltham and Boston,
Massachusetts
Corpora Amylacea: A Marker for Mesial Temporal Sclerosis. MARILDA H. CHUNG, MD AND DIKRAN S. HOROUPIAN,
MD, Stanford, California
Developmental Changes in Neurotransmitter Receptor Binding in the Human Periaqueductal Gray. SaTHyA C.
REDDY, ASHOK PANIGRAHY, W. FROST WHITE, AND HANNAH C. KINNEY, Boston, Massachusetts and Groton, Con-
necticut
Proximal Sciatic Axotomy Does Not Inhibit the Induction of Neurofilamentous Inclusions Following Intracisternal
Aluminum Chloride Exposure. MICHAEL J. STRONG AND SILVIA GAYTAN-GarRCIA, London, Ontario, Canada
Localization of E-cadherin in Peripheral Glia after Nerve Injury and Repair. MitsuHIRO HASEGAWA, MD, PHD,
AKIRA SETO, MD, NAOYUKI UCHIYAMA, MD, PHD, SHINYA KiIDA, MD, PHD, TETSUMORI YAMASHIMA, MD, PHD, AND
JUNKOH YAMASHITA, MD, PHD, Kanazawa, Japan
Major Histocompatibility Complex Class I Expression on Neurons in Subacute Sclerosing Panencephalitis and
Experimental Subacute Measles Encephalitis. NiTIN GOGATE, PEGGY SWOVELAND, TOSHIO YAMABE, LALIT VERMA,
JOANNA WOYCIECHOWSKA, EUGENIA TARNOWSKA-DZIDUSZKO, JERZY DYMECKI, AND SUHAYL DHIB-JALBUT, Baltimore,
Maryland, Duluth, Minnesota, and Warsaw, Poland
Immunolocalization and Redistribution of the FAC1 Protein in Alzheimer’s Disease. SUSAN SCHOONOVER, MS, PETER
Davies, PHD, AND ROBERT Bowser, PHD, Pittsburgh, Pennsylvania and Bronx, New York
a6B4 and a6f1 Integrins in Astrocytomas and Other CNS Tumors. STEFANO PREVITALI, MD, ANGELO QUATTRINI,
MD, RAFFAELLO NEMNI, MD, GIuLIO TRUCI, MD, ALESSANDRO Ducati, MD, LAWRENCE WRABETZ, MD, AND NICOLA
CANAL, MD, Milan, Italy
Neuronal Argyrophilia and Phosphorylated Neurofilament Accumulation Secondary to Deafferentation R. M.
TORACK, MD, K. A. RoTH, MD, PHD, AND J. W. MILLER, MD, PHD, St. Louis, Missouri
The Significance of Measles Virus Antigen and Genome Distribution in the CNS in SSPE for Mechanisms of Viral
Spread and Demyelination. INGRID V. ALLEN, DSc, STEPHEN McQualIb, MSc, JILL MCMAHON, MPHIL, JOHN KIRK,
PHD, AND ROBERT MCCONNELL, BSc, Belfast, Ireland
Intense Superoxide Dismutase-1 Immunoreactivity in Intracytoplasmic Hyaline Inclusions of Familial Amyotro-
phic Lateral Sclerosis with Posterior Column Involvement. Noriyuki SHIBATA, MD, ASAO HIRANO, MD, MAKIO
KOBAYASHI, MD, TEEPU SIDDIQUE, MD, HAN-XIANG DENG, MD, Wu-YEN HuNG, PHD, TAKEO Kato, MD, AND
KOHTARO ASAYAMA, MD, Tokyo, Yamagata City, and Yamanashi, Japan and Bronx, New York
Expression of the Very Low-Density Lipoprotein Receptor (VLDL-r), an Apolipoprotein-E Receptor in the Central
Nervous System and in Alzheimer’s Disease. RICHARD H. CHRISTIE, BS, HAEYONG CHUNG, BA, G. WILLIAM
REBECK, PHD, DUDLEY STRICKLAND, PHD, AND BRADLEY T. HYMAN, MD, PHD, Boston, Massachusetts and Rockville,
Maryland
NUMBER 5, MAy, 1996
Glial Inclusions in CNS Degenerative Diseases. STEVEN S.-M. CHIN, MD, PHD AND JAMES E. GOLDMAN, MD, PHD, New
York, New York
In Situ Hybridization Analysis for Expression of Myogenic Regulatory Factors in Regenerating Muscle of mdx
Mouse. S. BHAGWATI, MD, A. GHATPANDE, MS, S. A. SHAFIQ, PHD, AND B. LEUNG, BS, Brooklyn, New York
Expression of Tumor Necrosis Factor a (TNFa) and Interleukin 6 (IL-6) mRNA in Adult Human Astrocytes:
Comparison with Adult Microglia and Fetal Astrocytes. LOUISE LAFORTUNE, MSc, JOSEPHINE NALBANTOGLU,
PHD, AND JACK P. ANTEL, MD, Montreal, Quebec, Canada
Expression of Growth Factors and Growth Factor Receptors in Capillary Hemangioblastoma. Tom BOHLING, MD,
Erika Hatva, MSc, MINNA KUJALA, MEDSTUD, LENA CLAESSON-WELSH, MD, Kari ALITALO, MD, PHD, AND MATTI
HALTIA, MD, Helsinki, Finland and Uppsala, Sweden
Differential Expression of Versican Isoforms in Brain Tumors. WERNER PAULUS, MD, INGE Baur, BA, Maria T.
Dours-ZIMMERMANN, MS, AND DIETER R. ZIMMERMANN, PHD, Zurich, Switzerland
Neurofibrillary Tangles in Progressive Supranuclear Palsy Contain the Same Tau Epitopes Identified in Alzhei-
mer’s Disease PHFtau. MAriE LUISE SCHMIDT, PHD, RICHARD HUANG, BS, JOHN A. MARTIN, BS, JEWEL HENLEY,
BS, MADHUMALTI MAWAL-DEwAN, PHD, Howarp I. Hurtic, MD, VIRGINIA M.-Y. LEE, PHD, AND JOHN Q. TROJA-
NOWSKI, MD, PHD, Philadelphia, Pennsylvania
Production and Characterization of Two Ependymoma Xenografts. ROGER E. MCLENDON, MD, Kar-MING FUNG,
MD, PHD, REx C. BENTLEY, MD, B. K. AHMED RASHEED, PHD, JOHN Q. TROJANOWSKI, MD, PHD, SANDRA H.
BIGNER, MD, DareELL D. BIGNER, MD, PHD, AND HENRY S. FRIEDMAN, MD, Durham, North Carolina and Phila-
delphia, Pennsylvania
Myofibrillar Myopathy with Abnormal Foci of Desmin Positivity. I. Light and Electron Microscopy Analysis of
10 Cases. SATOSHI NAKANO, MD, ANDREW G. ENGEL, MD, ANDREW J. WACLAWIK, MD, ALISON M. EMSLIE-SMITH,
MD, PHD, AND Nel A. Busis, MD, Rochester, Minnesota and Pittsburgh, Pennsylvania
Myofibrillar Myopathy with Abnormal Foci of Desmin Positivity. II. Immunocytochemical Analysis Reveals Ac-
cumulation of Multiple Other Proteins. JAN L. DE BLEECKER, ANDREW G. ENGEL, AND BIRGIT B. ERTL, Rochester,
Minnesota
Role of Complement in the Aetiology of Pick’s Disease? S. K. SINGHRAO, MI BIOL, J. W.N EAL, MRCPatH, P. GASQUE,
PHD, B. P. MorGAN, PHD, AND G. R. NEWMAN, PHD, Cardiff, UK
Reinduction of Hyponatremia Improves Survival in Rats with Myelinolysis-related Neurologic Symptoms. ALAIN
SOUPART, MD, RAYMOND PENNINCKX, BSc, ALAIN STENUIT, MD, OLIVIER PERIER, MD, PHD, AND Guy DECAUx, MD,
PHD, Brussels, Beligum
Book Reviews
Neuropathological Diagnostic Criteria from Brain Banking. F E Cruz-Sanchez, R. David, and M. L. Cuzner, Eds.
(C. K. Petiro, MD)
Cellular Aging and Cell Death. N. J. Holbrook, G. R. Martin, and R. A. Lockshin, Eds. (C. K. Petrro, MD)
Letter to the Editor
Intracerebral Targets and Immunomodulation of Murine Lysteria monocytogenes Meningoencephalitis. D.L. Mont-
gomery, DVM, PhD and R.W. Storts, DVM, PhD
Abstracts—72nd Annual Meeting of the American Association of Neuropathologists, Inc. ..........................2.005
NUMBER 6, JUNE, 1996
Two Models for Multiple Sclerosis: Experimental Allergic Encephalomyelitis and Theiler’s Murine Encephalo-
myelitis Virus. Ikuo TsUNoDA, MD, PHD AND RoBERT S. FUJINAMI, PHD, Salt Lake City, Utah
Myoblast Transplantation in Monkeys: Control of Immune Response by FK506. I. Kinosuita, MD, R. Roy, PHD,
F J. DuGré, PHD, C. GRAVEL, PHD, B. Roy, M. GOuLET, I. ASSELIN, MSc, AND J.P. TREMBLAY, PHD, Quebec and
Sainte-Foy, Canada
The Paralysé Mouse Mutant: A New Animal Model of Anterior Horn Motor Neuron Degeneration. LUCIEN J.
HOUENOU, PHD, BRIGITTE BLONDET, PHD, Linx! Li, MD, PHD, MoniqQUE MurAwsky, MS, RONALD W. OPPENHEIM,
PHD, AND FRANCOIS RIEGER, PHD, Winston-Salem, North Carolina and Paris, France
Colocalization of Lysosomal Hydrolase and B-Amyloid in Diffuse Plaques of the Cerebellum and Striatum in
Alzheimer’s Disease and Down’s Syndrome. ANNE M. CaTALpo, Jopy L. BARNETT, DAviD M. A. MANN, AND
RALPH A. NIXON, Belmont, Massachusetts and Manchester, England
A Monoclonal Antibody that Specifically Recognizes a Novel Mitochondrial Protein of Human Astrocytes. HIDEAKI
Yokoo, MD, ATsusHI SASAKI, MD, JUNKO Hirato, MD, AND YOICHI NAKAZATO, MD, Gunma, Japan
Anti-Inflammatory Treatment Influences Neuronal Apoptotic Cell Death in the Dentate Gyrus in Experimental
Pneumococcal Meningitis. GREGoR Zysk, MD, WOLFGANG BRUCK, MD, JOACHIM GERBER, YVONNE BRUCK, MD,
HILMAR W. PRANGE, MD, AND ROLAND Nau, MD, Géttingen, Germany
DNA Amplification in Glial Cells of Progressive Multifocal Leukoencephalopathy: An Image Analysis Study.
AURELIO ARIZA, MD, José L. MATE, MD, SERGI SERRANO, MD, Marc ISAMAT, PHD, URSULA KEYsERS, BS, CARME
ARACIL, BS, AND JosE J. NAVAS-PALACcIOs, MD, Barcelona, Spain
Temporal and Spatial Expression of Major Myelin Proteins in the Human Fetal Spinal Cord During the Second
Trimester. KAREN M. WEIDENHEIM, SURENDER R. BODHIREDDY, WILLIAM K. RASHBAUM, AND WILLIAM D. Ly-
MAN, Bronx, New York
Referees for the Journal of Neuropathology and Experimental Neurology
NUMBER 7, JULY, 1996
Amyotrophic Lateral Sclerosis: Recent Advances in Understanding Disease Mechanisms. J. DE BELLEROCHE, PHD,
R. W. ORRELL, MB, CHB, MRCP, AND L. ViRGO, PHD. London, United Kingdom
Developmental Neuropathology and Impact of Perinatal Brain Damage. I: Hemorrhagic Lesions of Neocortex.
MIGUEL MarRiN-PADILLA, MD. Hanover, New Hampshire
Difference in Expression of Phosphorylated Tau Epitopes between Sporadic Inclusion-body Myositis and Hered-
itary Inclusion-body Myopathies. MAssIMILIANO MIRABELLA, MD, RENATE B. ALVAREZ, MS, MASAKO BILAK, PHD,
W. KING ENGEL, MD, AND VALERIE ASKANAS, MD, PHD. Los Angeles, California
Kainate-induced Brain Lesion: Similar Local and Remote Histopathological and Molecular Changes as in Ischemic
Brain Infarct. H. Mei Liu, MD, De LIANG LEI, MD, AND DonG LIANG YANG, MD. Hunan, China
Evidence for Central Nervous System Glial Cell Plasticity in Phenylketonuria. CHARISSA A. DYER, ADY KENDLER,
THOMAS PHILIBOTTE, PAULA GARDINER, JONATHAN CRUZ, AND HARVEY L. Levy. Waltham and Boston, Massachu-
Animal Model Balamuthia Mandrillaris CNS Infection: Contrast and Comparison in Immunodeficient and Im-
munocompetent Mice: A Murine Model of ‘‘Granulomatous’’ Amebic Encephalitis. KLAUS JANITSCHKE, A.
JULIO MARTINEZ, GOVINDA S. VISVESVARA, AND FREDERICK SCHUSTER. Atlanta, Georgia, Brooklyn, New York, Pitts-
burgh, Pennsylvania, and Berlin, Germany
Analysis of p53 Mutation and Epidermal Growth Factor Receptor Amplification in Recurrent Gliomas with
Malignant Progression. JULIA REIFENBERGER, MD, GUDRUN U. RING, MD, UrsuLa Gigs, MD, J. M. J. Lupwic
COoBBERS, PHD, JURGEN OBERSTRAB, PHD, HAN-XIANG AN, MD, DIETER NIEDERACHER, PHD, WOLFGANG WECHSLER,
MD, AND GUIDO REIFENBERGER, MD. Diisseldorf, Germany
Chronic Seizures Increase Glucose Transporter Abundance in Rat Brain. KATHRYN M. GRONLUND, MS, Davip Z.
GERHART, PHD, RICHARD L. LEINO, PHD, ANTHONY L. MCCALL, MD, PHD, AND LESTER R. DREwEs, PHD. Duluth,
Minnesota and Portland, Oregon
Brainstem Tegmental Necrosis and Olivary Hypoplasia: A Lethal Entity Associated with Congenital Apnea. SELINA
C. CorTEZ, MD, AND HANNAH C. KINNEY, MD. Providence, Rhode Island and Boston, Massachusetts
Prolonged Calpain-mediated Spectrin Breakdown Occurs Regionally Following Experimental Brain Injury in the
Rat. KATHRYN E. SAATMAN, PHD, DONNA BOZzyCZKO-COYNE, PHD, VAL Marcy, BS, ROBERT SIMAN, PHD, AND
TRAcY K. McINTOSH, PHD. Philadelphia and West Chester, Pennsylvania
NUMBER 8, AUGUST, 1996
Neurobiological Bases of Age-Related Cognitive Decline in the Rhesus Monkey. A. Peters, D.L. ROSENE, M.B.
Moss, T.L. KEMPER, C.R. ABRAHAM, J. TIGGES, AND M.S. ALBERT. Boston, Massachusetts and Atlanta, Georgia ...
Continuous Quality Improvement (CQI) in Neuropathology. Gary S. PEARL, MD, PHD AND JAMEs S. NELSON,
MD. Orlando, Florida and New Orleans, Louisiana
Cold-Injury of the Cerebral Cortex: Immunolocalization of Cellular Proteins and Blood-Brain Barrier Perme-
ability Studies. SukriTI NAG, MD, PHD, FRCPC. Toronto, Ontario, Canada
Characterization of the Precursor Protein of the Non-AB Component of Senile Plaques (NACP) in the Human
Central Nervous System. MICHAEL C. IRIZARRY, MD, TAE-WAN KIM, PHD, MEGAN MCNAmara, BS, RUDOLPH E.
TANZI, PHD, JULIA M. GEORGE, PHD, DAvip E CLAYTON, PHD, AND BRADLEY T. HYMAN, PHD. Charlestown, Mas-
sachusetts and Urbana, Illinois
Dystrophin, Utrophin and B-Dystroglycan Expression in Skeletal Muscle from Patients with Becker Muscular
Dystrophy. MASAKAzU KawasirI, MD, TAKAO Mitsui, MD, Hisaomi KAwal, MD, TAKASHI KOBUNAI, PHD, TAK-
AYUKI TSUCHIHASHI, MD, AND SHIRO Saito, MD. Tokushima, Japan
1,25 Dihydroxyvitamin D, Exerts Regional Effects in the Central Nervous System during Experimental Allergic
Encephalomyelitis. S. NATAF, MD, E. Garcion, PHD, E Darcy, PHD, D. CHABANNES, PHD, J.Y. MULLER, MD,
AND P. BRACHET, PHD. Angers and Nantes, France
Localization and Expression of Ciliary Neurotrophic Factor (CNTF) in Postmortem Sciatic Nerve from Patients
with Motor Neuron Disease and Diabetic Neuropathy. DEBORAH A. LEE, MD, PHD, LOUANN Gross, DEBRA A.
WITTROCK, AND ANTHONY J. WINDEBANK, MD. New Orleans, Louisiana and Rochester, Minnesota
Reduction of Calcineurin Enzymatic Activity in Alzheimer’s Disease: Correlation with Neuropathologic Changes.
CHRISTOPHER J. LADNER, JULIE CZECH, JOANNA MAURICE, STANLEY A. LORENS, AND JOHN M. LEE. Chicago and
Maywood, Illinois
Ultrastructural Study of the Synapses of Central Chromatolytic Anterior Horn Cells in Motor Neuron Disease.
SHOICHI SASAKI, MD AND Makoto Iwata, MD. Tokyo, Japan
In Memoriam
Kenneth Martin Earle, MD, MSc (1919-1996) (JOHN M. HARDMAN, MD)
Book Review
Neuroglia. H. Kettenmann and B.R. Ransom, eds. (JEAN E. MERRILL, PHD)
NUMBER 9, SEPTEMBER, 1996
The Cell Biology of Myelin Degeneration and Regeneration in the Peripheral Nervous System. JEFFREY F GOODRUM
AND THOMAS W. BOouLDIN. Chapel Hill, North Carolina
a-Calcium-Calmodulin-Dependent Kinase II Is Associated with Paired Helical Filaments of Alzheimer’s Disease.
JINSONG XIAO, GEORGE PERRY, JUAN TRONCOSO, AND MERVYN J. MONTIERO. Cleveland, Ohio and Baltimore, Mary-
Reduction of Acetylated a-Tubulin Immunoreactivity in Neurofibrillary Tangle-bearing Neurons in Alzheimer’s
Disease. BART HEMPEN, BS AND JEAN-PIERRE BRION, MD, PHD. Brussels, Belgium
The Glial and Mesenchymal Elements of Gliosarcomas Share Similar Genetic Alterations. RUDOLF H. BOERMAN,
MD, PHD, Kari ANDERL, JOHN HERATH, THOMAS BORELL, NICOLA JOHNSON, JANET SCHAEFFER-KLEIN, ALLEN
KIRCHHOF, ANTON K. RAAP, PHD, BERND W. SCHEITHAUER, MD, AND ROBERT B. JENKINS, MD, PHD. Rochester,
Minnesota, Nijmegen and Leiden, The Netherlands, and Oxford, United Kingdom
Histopathologic and Physiologic Effects of Chronic Implantation of Microelectrodes in Sacral Spinal Cord of the
Cat. BARBARA J. WOODFORD, PHD, RANDY R. CARTER, PHD, DOUGLAS McCREERY, PHD, LEO A. BULLARA, BS, AND
WILLIAM F. AGNEw, PHD. Pasadena, California
Multifocal Remitting-Relapsing Cerebral Demyelination Twenty Years Following Allogenic Bone Marrow Trans-
plantation. P. KELLY, MRCPI, H. STAUNTON, FRCPI, M. LAWLER, PHD, P. BRENNAN, FRCR, S. JENNINGS, E. R.
UNGER, MD, J. H. SUNG, MD, AND M. A. FARRELL, FRCPATH. Dublin, Ireland, Atlanta, Georgia, and Minneapolis,
Minnesota
Ependymal Denudation, Aqueductal Obliteration and Hydrocephalus after a Single Injection of Neuraminidase
into the Lateral Ventricle of Adult Rats. J. M. GRONDONA, MD, M. PEREZ-MARTiN, M. CIFUENTES, MD, J. PEREZ,
MD, A. J. JIMENEZ, MD, J. M. PEREZ-FiGARES, MD, AND P. FERNANDEZ-LLEBREZ, MD. Mdlaga, Spain
Reduced Cyclin D1 Expression in the Cerebella of Nutritionally Deprived Rats Correlates with Developmental
Delay and Decreased Cellular DNA Synthesis. GEORGE E. SHAMBAUGH III, RICHARD J. LEE, GENICHI WATANABE,
FRANK ERFURTH, ANTHONY N. KARNEZIS, ALISA E. KOCH, GEORGE K. HAINES III, MARGARET HALLORAN, BETTY A.
BRODY, AND RICHARD G. PESTELL. Chicago, Illinois
Book Review
Congenital Malformations of the Brain. Pathologic, Embryologic, Clinical, Radiologic and Genetic Aspects. M. G.
Norman, B. C. McGillivray, D. K. Kalousek, A. Hill, and K. J. Poskitt. (CARL BOESEL, MD)
Letter to the Editor
Harvey B. Sarnat, MD, FRCPC
NUMBER 10, OCTOBER, 1996
The Pathogenesis of Alzheimer Disease: An Alternative to the Amyloid Hypothesis. RoBErRT D. TERRY, MD. La
Jolla, California
Malignant Astrocytomas with Homozygous CDKN2/p16 Gene Deletions Have Higher Ki-67 Proliferation Indices.
YASUHIRO ONO, TAKASHI TAMIYA, TOMOTSUGU ICHIKAWA, KATSUZOU KUNISHIO, KENGO MATSUMOTO, TOMOHISA Fu-
RUTA, TAKASHI OHMOTO, KEISUKE UEKI, AND DAvID N. Louis. Okayama, Japan and Boston, Massachusetts
Stereological Analysis of Cerebral Atrophy in Human Immunodeficiency Virus-associated Dementia. PONNI SuB-
BIAH, MD, PETER MouTON, PHD, HELEN FEDor, BS, JustIN C. MCARTHUR, MBBS, MPH, AND JONATHAN D. Gass,
MD. Baltimore, Maryland and Atlanta, Georgia
Profiles of Neuronal Thread Protein Expression in Alzheimer’s Disease. SUZANNE M. DE LA MONTE, ROLF I. CARLSON,
NANCY V. BROWN, AND JACK R. WANDS. Boston and Charlestown, Massachusetts
Identification of Phosphorylation Sites in PHF-TAU from Patients with Guam Amyotrophic Lateral Sclerosis/
Parkinsonism-dementia Complex. MADHUMALTI MAWAL-DEwaN, PHD, M. LuIsE SCHMIDT, PHD, BRIAN BALIN,
PHD, DANIEL P. PERL, MD, VirGINIA M.-Y LEE, PHD, AND JOHN Q. TROJANOWSKI, MD, PHD. Philadelphia, Penn-
sylvania and New York, New York
Distribution of Immunoglobulin Superfamily Members ICAM-1, -2, -3, and the B2 Integrin LFA-1 in Multiple
Sclerosis Lesions. LArs BO, MD, JOHN W. PETERSON, BS, SVERRE Mork, MD, Patricia A. HOFFMAN, MS, W.
MICHAEL GALLATIN, PHD, RICHARD M. RANSOHOFF, MD, AND Bruce D. Trapp, PHD. Cleveland, Ohio, Bergen,
Norway, and Bothell, Washington
Distribution of B-amyloid Precursor and B-cell Lymphoma Protooncogene Proteins in the Rat Retina after Optic
Nerve Transection or Vascular Lesion. SHUR-TZU CHEN, PHD, STEPHEN M. GENTLEMAN, PHD, LAURENCE J. GAREY,
DpxHiIL, BM BCu, AND LING SuN JEN, PHD. Taiwan, China and London, United Kingdom
Inflammation, AB Deposition, and Neurofibrillary Tangle Formation as Correlates of Alzheimer’s Disease Neu-
rodegeneration. LIH-FEN LUE, PHD, LIBUSE BRACHOVA, PHD, W. HAROLD Civin, MD, AND JOSEPH ROGERS, PHD. Sun
City, Arizona
Familial Amyotrophic Lateral Sclerosis with a Two Base Pair Deletion in Superoxide Dismutase 1 Gene: Multi-
system Degeneration with Intracytoplasmic Hyaline Inclusions in Astrocytes. SHINSUKE KATO, MD, MASARU
SHIMODA, MD, YASUHIRO WATANABE, MD, KENJI NAKASHIMA, MD, KAzuRO TAKAHASHI, MD, AND EISAKU OHAMA,
MD. Yonago, Japan
In Memoriam
Murray B. Bornstein. (ROBERT D. TERRY, MD)
Book Received
Neurophysiology, 3rd ed. R. H. S. Carpenter. (MICHAEL NOEL Hart, MD)
NUMBER 11, NOVEMBER, 1996
Inclusion Body Myositis, A Review. STIRLING CARPENTER, MD. Toronto, Ontario, Canada
Increasing Brain Tumor Rates: Is There a Link to Aspartame? JoHN W. OLNEY, MD, Nuri B. FARBER, EDWARD
SPITZNAGEL, AND LEE N. RoBins. St. Louis, Missouri
Tie Endothelial Cell-specific Receptor Tyrosine Kinase Is Upregulated in the Vasculature of Arteriovenous Mal-
formations. ERIKA HATvA, Msc, JUHA JAASKELAINEN, MD, HARRI HIRVONEN, MD, Kari ALITALO, MD, AND MatTrTI
HALTIA, MD. Helsinki and Turku, Finland
In Situ Labeling of Dying Cortical Neurons in Normal Aging and in Alzheimer’s Disease: Correlations with Senile
Plaques and Disease Progression. JUAN C. TRONCOSO, MD, RENAT R. SUKHOV, MD, CLaupia H. Kawas, MD,
AND VASSILIS E. KOLIATsos, MD. Baltimore, Maryland
Expression of Integrin avB3 in Small Blood Vessels of Glioblastoma Tumors. CANDECE L. GLADSON,
MD. Birmingham, Alabama
Growth and Development of Toxoplasma Gondii in Human Neurons and Astrocytes. S. K. HALONEN, W. D. LYMAN,
AND E C. Cuiu. Bronx, New York
Proteinase-K-Resistant Prion Protein Isoforms in Gerstmann-Striussler-Scheinker Disease (Indiana Kindred).
PEDRO PICCARDO, MD, CHARLES SEILER, BA, BS, STEPHEN R. DLOUHY, PHD, KATHERINE YOUNG, DPHIL, MARTIN R.
FARLOW, MD, FRANCES PRELLI, BS, BLAS FRANGIONE, MD, PHD, Orso BUGIANI, MD, FABRIZIO TAGLIAVINI, MD,
AND BERNARDINO GHETTI, MD. Indianapolis, Indiana, New York, New York, and Milano, Italy
Quantifying Apoptosis in Banked Human Brains Using Flow Cytometry. JUAN P. OLANO, MD, Dwayne WoLF, MD,
PHD, MICHAEL KEHERLY, PHD, AND BENJAMIN B. GELMAN, MD, PHD. Galveston, Texas
Book Reviews/Book Received
Technical Advances in AIDS Research in the Human Nervous System. Eugene O. Major and Jay A. Levy, eds. (C.
DAVID PAUZA)
Molecular Neuropathology. Gareth W. Roberts and Julia M. Polak, eds. (KEVIN A. ROTH, MD, PHD)
Etiology of Parkinson’s Disease. Jonas H. Ellenberg, William C. Koller, and J.. William Langston, eds. (MICHAEL
NoeEL Hart, MD)
Prion Diseases. Harry F Baker and Rosalind M. Ridley, eds. (MICHAEL NOEL HART, MD)
AANP Awards
AANP Meritorious Service Award Presented to Pasquale A. (Pat) Cancilla (MICHAEL NOEL Hart, MD)
AANP Award for Meritorious Contributions to Neuropathology Presented to Franz Seitelberger, MD (Epwarp P.
RICHARDSON, JR., MD)
Letter to the Editor
Difference in Expression of Phosphorylated Tau Epitopes between Sporadic Inclusion-body Myositis and Hereditary
Inclusion-body Myopathies. William I. Rosenblum, MD. REPLY: VALERIE ASKANAS, MD, PHD AND W. KING
NUMBER 12, DECEMBER, 1996
Pathologic Alterations in the Diabetic Neuropathies of Humans: A Review. PETER JAMES DycK, MD AND CATERINA
GIANNINI, MD, PHD. Rochester, Minnesota and Treviso, Italy
The Expression of Tissue-type Plasminogen Activator, Matrix Metalloproteases and Endogenous Inhibitors in the
Central Nervous System in Multiple Sclerosis: Comparison of Stages in Lesion Evolution. M. LOUISE CUZNER,
DsorpsE GVERIC, CATHERINE STRAND, A. JANE LOUGHLIN, LIESBET PAEMEN, GHISLAIN OPDENAKKER, AND JIA NEw-
COMBE. London, United Kingdom and Leuven, Belgium
MHC Class I-Mediated Cytotoxicity Does Not Induce Apoptosis in Muscle Fibers nor in Inflammatory T Cells:
Studies in Patients with Polymyositis, Dermatomyositis, and Inclusion Body Myositis. CHRISTIANE SCHNEIDER,
MD, RALF GoLp, MD, Marinos C. DALAKAS, MD, MASCHA SCHMIED, MD, Hans LASSMANN, MD, Ka us V. ToyKa,
MD, AND HANS-PETER HARTUNG, MD. Wiirzburg, Germany and Vienna, Austria
Distinct Patterns of Neuronal Loss and Alzheimer’s Disease Lesion Distribution in Elderly Individuals Older than
90 Years. PANTELEIMON GIANNAKOPOULOS, MD, PATRICK R. Hor, MD, ENIKO KOvari, MD, PHILIPPE G. VALLET,
PHD, FrRANCoIs R. HERRMANN, MD, MPH, AND CONSTANTIN Bouras, MD. Geneva, Switzerland and New York, New
Regional Heterogeneity in the Response of Astrocytes following Traumatic Brain Injury in the Adult Rat. SANDRA
J. HILL, ELisA BARBARESE, AND TRACY K. MCINTOSH. Farmington, Connecticut and Philadelphia, Pennsylvania ....
Myotoxic Activity of the Toxic Phospholipase, Notexin, from the Venom of the Australian Tiger Snake. RUPERT
W. Drxon, PHD AND JOHN B. Harris, PHD. Newcastle upon Tyne, United Kingdom
Classification of Astrocytomas and Malignant Astrocytomas by Principal Components Analysis and a Neural Net.
MarTIN J. MCKEown, BENG, MD, FRCP(C) AND Davip A. RAMSAY, MB CHB, FRCP(C), DPHIL. Ontario, Canada
and La Jolla, California
The Clinical Significance of Extracellular Matrix in Gangliogliomas. PAMELA B. JAFFEY, MD, ARNO J. MuUNDT, MD,
Davip A. BAUNOCH, PHD, DAWNA L. ARMSTRONG, MD, WINIFRED J. HAMILTON, PHD, VIRGINIA G. ZAGAJA, MT
(ASCP), RoBERT G. GROSSMAN, MD, AND ROBERT L. WOLLMANN, MD. Chicago, Illinois
Progenitor Cell Proliferation Outside the Ventricular and Subventricular Zones during Human Brain Develop-
ment. ADY KENDLER, MD, PHD AND JEFFREY A. GOLDEN, MD. Boston, Massachusetts and Philadelphia, Pennsyl-
Therapy of a Murine Model of Pediatric Brain Tumors Using a Herpes Simplex Virus Type-1 ICP34.5 Mutant
and Demonstration of Viral Replication within the CNS. Topp M. LASNER, MD, SANTOSH KESARI, PHD, S.
MoirrA BROWN, PHD, VIRGINIA M.-Y. LEE, PHD, NIGEL W. FRASER, PHD, AND JOHN Q. TROJANOWSKI, MD,
PuD. Philadelphia, Pennsylvania and Glasgow, Scotland
Variable Imprinting of H19 and IGF2 in Fetal Cerebellum and Medulloblastoma. STEFFEN ALBRECHT, MD, ANDREAS
Wana, MSc, ANKE Kocu, MSc, JURGEN A. Kraus, MD, CYNTHIA G. GOODYER, PHD, AND TORSTEN PIETSCH,
MD. Montreal, Canada and Bonn, Germany
Book Review
The Cortical Neuron. Michael J. Gutnick and Istvan Mody. (WILLIAM O. WHETSELL, JR., MD)
Letters to the Editor
Validity and Reliability of the Preliminary NINDS Neuropathologic Criteria for Progressive Supranuclear Palsy
and Related Disorders. Kenji Ikeda, MD, PhD and Haruhiko Akiyama, MD, PhD. RepLy: IRENE LITVAN,
Increasing Brain Tumor Rates: Is There a Link to Aspartame? PAauL 'S. LEvy, SCD AND DON HEDECKER, PHD
Author Index
Subject Index