Journal of Cell Biology 1996: Vol 135 Table of Contents

9 Pages·1996·0.48 MB·English

Contents:
Volume 135, Number 1, October 1996
Mini-review
1 A unified nomenclature for peroxisome 97 The SH3 domain of the Saccharomyces cerevisiae
biogenesis factors. peroxisomal membrane protein Pexl3p
B. Distel, R. Erdmann. S.J. Gould, G. Blobel, functions as a docking site for PexSp, a mobile
D.I. Crane, J.M. Cregg, G. Dodt, Y. Fujiki. receptor for the import of PTSl-containing
J.M. Goodman. W.W. Just, J.A.K.W. Kiel, proteins.
W.-H. Kunau, P.B. Lazarow, G.P. Mannaerts,
H. W. Moser, T. Osumi, R.A. Rachubinski, A. Roscher, Y. Elgersma, L. Kwast. A. Klein, T. Voom-Brouwer,
S. Subramani, H.F. Tabak. T. Tsukamoto, D. Valle, M. van den Berg, B. Metzig, T. America. H.F. Tabak,
I. van der Klei, P.P. van Veldhoven, and M. Veenhuis and B. Distel
Commentary 111 Identification of PexlSp, a peroxisomal
membrane receptor for the PTSl recognition
5 Protofilaments and rings, two conformations of
factor.
the tubulin family conserved from bacterial FtsZ
to a/p and 7 tubulin. R. Erdmann and G. Blobel
H.P. Erickson and D. Stoffler 123 Redox-sensitive homodimerization of Pexllp:
A proposed mechanism to regulate peroxisomal
Regular Articles
division.
9 Localization of HIV-1 RNA in mammalian
P.A. Marshall, J.M. Dyer, M.E. Quick,
nuclei. and J.M. Goodman
G. Zhang, M.L. Zapp, G. Yan, and M.R. Green
139 Apical and basolateral endosomes of MDCK
19 The organization of endoplasmic reticulum cells are interconnected and contain a polarized
export complexes. sorting mechanism.
S.I. Bannykh, T. Rowe, and W.E. Balch G. Odorizzi. A. Pearse, D. Domingo, I.S. Trowbridge,
and C.R. Hopkins
37 Regulation mechanism of ERM
(ezrin/radixin/moesin) protein/plasma 153 Rab8 promotes polarized membrane transport
membrane association; Possible involvement throu^ reorganization of actin and microtubules
of phosphatidylinositol turnover and in fibroblasts.
Rho-dependent signaling pathway. J. Peranen. P. Auvinen, H. Virta, R. Wepf,
and K. Simons
M. Hirao, N. Sato, T. Kondo, S. Yonemura,
M. Monden, T. Sasaki. Y. Takai, S. Tsukita,
169 Dynamics of capping protein and actin assembly
and S. Tsukita
in vitro: Uncapping barbed ends by
53 Architecture of coatomer: Molecular polyphosphoinositides.
characterization of 8-COP and protein
D.A. Schafer, P.B. Jennings, and J.A. Cooper
interactions within the complex.
181 Calcium waves along the cleavage furrows in
D. Faulstich, S. Auerbach, L. Orci, M. Ravazzola.
S. Wegehingel, F. Lottspeich, G. Stenbeck, C. Harter, cleavage-stage Xenopus embryos and its
F.T. Wieland, and H. Tschochner inhibition by heparin.
A. Muto, S. Kume, T. Inoue, H. Okano,
63 Dilation of the influenza hemagglutinin fusion
and K. Mikoshiba
pore revealed by the kinetics of individual
cell-cell fusion events. 191 Local perinuclear calcium signals associated with
mitosis-entry in early sea urchin embryos.
R. Blumenthal, D.P. Sarkar, S. Durell, D.E. Howard,
and S.J. Morris M. Wilding, E.M. Wright, R. Patel, G. Ellis-Davies,
and M. Whitaker
73 Truncation of the COOH-terminal region of the
paramyxovirus SV5 fusion protein leads to 201 Microtubule dynamics at the G2/M transition:
hemifusion but not complete fusion. Abrupt breakdown of cytoplasmic microtubules
at nuclear envelope breakdown and implications
S. Bagai and R.A. Lamb
for spindle morphogenesis.
85 Pexl3p is an SH3 protein of the peroxisome
Y. Zhai, P.J. Kronebusch, P.M. Simon,
membrane and a docking factor for the and G.G. Borisy
predominantly cytoplasmic PTSl receptor.
S.J. Gould, J.E. Kalish, J.C. Morrell, J. Bjorkman,
A.J. Urquhart, and D.I. Crane
215 Targeted mutation of plakoglobin in mice reveals 253 Intracellular signaling is changed after clustering
essential functions of desmosomes in the of the neural cell adhesion molecules axonin-1
embryonic heart. and NgCAM during neurite fasciculation.
P. Ruiz, V. Brinkmann, B. Ledermann. M. Behrend, S. Kunz, U. Ziegler, B. Kunz, and P. Sonderegger
C. Grund, C. Thalhammer, F. Vogel, C. Birchmeier,
U. Giinthert, W.W. Franke, and W. Birchmeier 269 A developmental defect in Plasmodium
falciparum male gametogenesis.
227 Overexpression of bone morphogenetic protein-6
F. Guinet, J.A. Dvorak, H. Fujioka, D.B. Keister,
(BMP-6) in the epidermis of transgenic mice:
O. Muratova, D.C. Kaslow, M. Aikawa, A.B. Vaidya,
Inhibition or stimulation of proliferation and T.E. Wellems
depending on the pattern of transgene expression
and formation of psoriatic lesions. 279 Mast cells that reside at different locations in the
jejunum of mice infected with Trichinella spiralis
M. Blessing, P. Schirmacher, and S. Kaiser
exhibit sequential changes in their granule
241 Altered secondary myogenesis in transgenic ultrastructure and chymase phenotype.
animals expressing the neural cell adhesion D.S. Friend, N. Ghildyal, K.F. Austen, M.F. Gurish,
molecule under the control of a skeletal muscle R. Matsumoto, and R.L. Stevens
a-actin promoter.
S. Fazeli, D.J. Wells, C. Hobbs, and F.S. Walsh
Volume 135, Number 2, October 1996
Commentary
383 Plus-end motors override minus-end motors
291 Switches, latches, and amplifiers: Common during transport of squid axon vesicles on
themes of G proteins and molecular motors. microtubules.
R.D. Vale V. Muresan, C.P. Godek, T.S. Reese, and B.J. Schnapp
Regular Articles 399 Opposing motor activities are required for the
303 Spliced exons of adenovirus late RNAs colocalize organization of the mammalian mitotic spindle
with snRNP in a specific nuclear domain. pole.
E. Bridge, K.-U. Riedel, B.-M. Johansson, T. Gaglio, A. Saredi, J.B. Bingham, M.J. Hasbani,
and U. Pettersson S.R. Gill, T.A. Schroer, and D.A. Compton
315 Kinetochores moving away from their associated 415 Insulin unmasks a COOH-terminal Glut4
pole do not exert a significant pushing force on epitope and increases glucose transport across
the chromosome. T-tubules in skeletal muscle.
A. Khodjakov and C.L. Rieder W. Wang, P.A. Hansen. B.A. Marshall, J.O. Holloszy,
and M. Mueckler
329 In vivo nuclear transport kinetics in
431 Proliferation precedes differentiation in
Saccharomyces cerevisiae: A role for heat shock
IGF-I-stimulated myogenesis.
protein 70 during targeting and translocation.
J.C. Engert, E.B. Berglund, and N. Rosenthal
N. Shulga, P. Roberts. Z. Gu, L. Spitz. M.M. Tabb,
M. Nomura, and D.S. Goldfarb 441 Skeletal muscle cells lacking the retinoblastoma
341 Protein targeting by tyrosine- and protein display defects in muscle gene expression
Di-leucine-based signals: Evidence for distinct and accumulate in S and G2 phases of the cell
saturable components. cycle.
M.S. Marks. L. Woodruff, H. Ohno, B.G. Novitch, G.J. Mulligan, T. Jacks, and A.B. Lassar
and J.S. Bonifacino
457 Myristylation of FBR v-fos dictates the
355 The production of post-Golgi vesicles requires differentiation pathways in malignant
a protein kinase C-like molecule, but not its osteosarcoma.
phosphorylating activity.
R.M. Jotte and J.T. Holt
J.-P. Simon. l.E. Ivanov, M. Adesnik,
and D.D. Sabatini 469 Characterization of a premeiotic germ
cell-specific cytoplasmic protein encoded by
371 Hydrophobicity variations along the surface of StraS, a novel retinoic acid-responsive gene.
the coiled-coil rod may mediate striated muscle
M. Oulad-Abdelghani. P. Bouillet, D. Decimo,
myosin assembly in Caenorhabditis elegans. A. Gansmuller, S. Heyberger, P. Dolle, S. Bronner,
P.E. Hoppe and R.H. Waterston Y. Lutz, and P. Chambon
IV
479 Dissecting processing and apoptotic activity of 511 Chloride ion efflux regulates adherence,
a cysteine protease by mutant analysis. spreading, and respiratory burst of neutrophils
B. Allet. A. Hochmann, I. Martinou, A. Berger, stimulated by tumor necrosis factor-a (TNF) on
M. Missotten, B. Antonsson, R. Sadoul, J.-C. Martinou, biologic surfaces.
and L. Bemasconi
R. Menegazzi, S. Busetto, P. Dri, R. Cramer,
and P. Patriarca
487 Lateral dimerization is required for the 523 P-Selectin glycoprotein ligand 1 is a ligand for
homophilic binding activity of C-cadherin. L-selectin on neutrophils, monocytes,
W.M. Brieher, A.S. Yap, and B.M. Gumbiner and CD34^ hematopoietic progenitor cells.
O. Spertini. A.-S. Cordey, N. Monai. L. Giuffre,
and M. Schapira
497 Polymorphonuclear leukocyte adhesion triggers
the disorganization of endothelial cell-to-cell 533 Thrombospondin modulates ttyPs function
adherens junctions. through integrin-associated protein.
A. Del Maschio, A. Zanetti, M. Corada, Y. Rival, A.-G. Gao, F.P. Lindberg, J.M. Dimitry, E.J. Brown,
L. Ruco, M.G. Lampugnani, and E. Dejana and W.A. Frazier
Volume 135, Number 3, November 1996
545 Dynamic elastic behavior of a-satellite DNA 647 The tandem repeat domain in the Listeria
domains visualized in situ in living human cells. monocytogenes ActA protein controls the rate
R.D. Shelby, K.M. Hahn, and K.F. Sullivan of actin-based motility, the percentage of
moving bacteria, and the localization of
559 RanBPl stabilizes the interaction of Ran with vasodilator-stimulated phosphoprotein and
p97 in nuclear protein import. profilin.
N.C. Chi, E.J.H. Adam, G.D. Visser, and S.A. Adam G.A. Smith, J.A. Theriot, and D.A. Portnoy
661 A new model for the interaction of dystrophin
571 Activation of an MAP kinase cascade leads to
with F-actin.
Sir3p hyperphosphorylation and strengthens
transcriptional silencing. I. N. Rybakova, K.J. Amann, and J.M. Ervasti
E.M. Stone and L. Pillus 673 Alterations in flight muscle ultrastructure and
function in Drosophila tropomyosin mutants.
585 Amino acid permeases require COPII
A.J. Kreuz, A. Simcox, and D. Maughan
components and the ER resident membrane
protein ShrSp for packaging into transport 689 Differential taxol-dependent arrest of
vesicles in vitro. transformed and non transformed cells in the GI
M.J. Kuehn, R. Schekman, and P.O. Ljungdahl phase of the cell cycle, and specific-related
mortality of transformed cells.
597 Differential trafficking and timed localization of M. O. Trielli, P.R. Andreassen, F.B. Lacroix,
two chitin synthase proteins, Chs2p and Chs3p. and R.L. Margolis
J.S. Chuang and R.W. Schekman 701 Delivery of newly synthesized tubulin to rapidly
growing distal axons of rat sympathetic neurons
611 Direct vesicular transport of MHC class II
in compartmented cultures.
molecules from lysosomal structures to the cell
surface. R.B. Campenot. K. Lund, and D.L. Senger
R. Wubbolts, M. Fernandez-Borja, L. Oomen, 711 Neurofilament subunit NF-H modulates axonal
D. Verwoerd, H. Janssen, J. Calafat, A. Tulp, diameter by selectively slowing neurofilament
S. Dusseljee, and J. Neefjes
transport.
623 A pathway for targeting soluble misfolded J. R. Marszalek, T.L. Williamson. M.K. Lee, Z. Xu,
P.N. Hoffman. M.W. Becher, T.O. Crawford,
proteins to the yeast vacuole.
and D.W. Cleveland
E. Hong. A.R. Davidson, and C.A. Kaiser
725 Pea2 protein of yeast is localized to sites of
635 In vivo phosphorylation of adaptors regulates polarized growth and is required for efficient
their interaction with clathrin. mating and bipolar budding.
A. Wilde and F.M. Brodsky N. Valtz and 1. Herskowitz
741 Role of the ABC transporter Ste6 in cell fusion 809 Membrane tethering enables an extracellular
during yeast conjugation. domain of the a cetylcholine receptor a subunit
L. Elia and L. Marsh to form a heterodimeric ligand-binding site.
Z.-Z. Wang. S.F. Hardy, and Z.W. Hall
753 Modular organization of the PDZ domains in the
819 Glycosaminoglycans can modulate extracellular
human discs-large protein suggests a mechanism
localization of the wingless protein and promote
for coupling PDZ domain-binding proteins to
signal transduction.
ATP and the membrane cytoskeieton.
F. Reichsman. L. Smith, and S. Cumberledge
S.M. Marfatia, J.H. Morais Cabral. L. Lin. C. Hough.
P.J. Bryant. L. Stolz. and A.H. Chishti 829 Genetic analysis of 04 integrin functions in the
development of mouse skeletal muscle.
767 The catenin/cadherin adhesion system is
J.T. Yang. T.A. Rando. W.A. Mohler. H. Rayburn.
localized in synaptic junctions bordering
H.M. Blau, and R.O. Hynes
transmitter release zones.
837 Sialylated, fucosylated ligands for L-selectin
N. Uchida. Y. Honjo. K.R. Johnson. M.J. Wheelock.
and M. Takeichi expressed on leukocytes mediate tethering and
rolling adhesions in physiologic flow conditions.
781 Developmental expression and distinctive R.C. Fuhlbrigge. R. Alon. K.D. Puri. J.B. Lowe,
tyrosine phosphorylation of the Eph-related and T.A. Springer
receptor tyrosine kinase Cek9.
849 Interactions through L-selectin between
C. Scans. J.A. Holash. Y. Pavlova, and E.B. Pasquale leukocytes and adherent leukocytes nucleate
rolling adhesions on selectins and VCAM-1 in
797 Synaptic vesicles have two distinct recycling shear flow.
pathways.
R. Alon. R.C. Fuhlbrigge. E.B. Finger,
J.H. Koenig and K. Ikeda and T.A. Springer
Volume 135, Number 4, November 1996
867 Structure, subnuclear distribution, and nuclear 953 F-actin sequesters elongation factor la from
matrix association of the mammalian telomeric interaction with aminoacyl-tRNA in a
complex. pH-dependent reaction.
M.E.E. Luderus. B. van Steensel, L. Chong, G. Liu, J. Tang, B.T. Edmonds, J. Murray,
O.C.M. Sibon. F.F.M. Cremers. and T. de Lange S. Levin, and J. Condeelis
883 In situ localization of mitochondrial DNA 965 Dictyostelium discoideum cells lacking the
replication in intact mammalian cells. 34,000-dalton actin-binding protein can grow,
A.F. Davis and D.A. Clayton locomote, and develop, but exhibit defects in
regulation of cell structure and movement:
895 COPII vesicles derived from mammalian
A case of partial redundancy.
endoplasmic reticulum microsomes recruit COPI.
F. Rivero, R. Furukawa. A.A. Noegel,
T. Rowe, M. Aridor, J.M. McCaffery, H. Plutner. and M. Fechheimer
C. Nuoffer, and W.E. Balch
981 Midzone microtubule bundles are continuously
913 Rabll regulates recycling through the required for cytokinesis in cultured epithelial
pericentriolar recycling endosome. cells.
O. Ullrich. S. Reinsch, S. Urbe, M. Zerial. S. P. Wheatley and Y.-l. Wang
and R.G. Parton
991 Plectin sidearms mediate interaction of
925 Mechanism of clathrin basket dissociation:
intermediate filaments with microtubules and
Separate functions of protein domains of the
other components of the cytoskeieton.
DnaJ homologue auxiiin.
T. M. Svitkina. A.B. Verkhovsky, and G.G. Borisy
S.E.H. Holstein, H. IJngewickell, and E. Ungewickell
1009 Plakophilins 2a and 2b: Constitutive proteins of
939 Inhibition of alanine: Glyoxylate
dual location in the karyoplasm and the
aminotransferase 1 dimerization is a prerequisite
desmosomal plaque.
for its peroxisome-to-mitochondrion
mistargeting in primary hyperoxaluria type 1. C. Mertens, C. Kuhn, and W.W. Franke
J.M. Leiper, P.B. Oatey. and C.J. Danpure
VI
1027 Characterization of pinin, a novel protein 1125 Two independent domains of hDlg are sufficient
associated with the desmosome-intermediate for subcellular targeting: The PDZl-2
filament complex. conformational unit and an alternatively spliced
P. Ouyang and S.P. Sugrue domain.
R. A. Lue, E. Brandin, E.P. Chan, and D. Branton
1043 Preferential MyoD homodimer formation
demonstrated by a general method of dominant
negative mutation employing fusion with a 1139 Regulated clustering of variant CD44 proteins
lysosomal protease. increases their hyaluronate binding capacity.
F.-Q. Li, A. Coonrod, and M. Honvitz J. Sleeman. W. Rudy, M. Hofmann, J. Moll,
P. Herrlich, and H. Ponta
1059 Neurofascin induces neurites by heterophilic
interactions with axonal NrCAM while NrCAM 1151 Differentiation modulates the balance of positive
requires Fll on the axonal surface to extend and negative Jun/AP-1 DNA binding activities to
neurites. regulate cellular proliferative potential: Different
effects in nontransformed and transformed cells.
H. Volkmer, R. Leuschner, U. Zacharias,
and F.G. Rathjen H. Wang. Z. Xie, and R.E. Scott
1071 Ventricular zone gene-1 {vzg-1) encodes a 1163 Distinct regions control transcriptional activation
lysophosphatidic acid receptor expressed in of the al(VI) collagen promoter in different
neurogenic regions of the developing cerebral tissues of transgenic mice.
cortex.
P. Braghetta. C. Fabbro, S. Piccolo, D. Marvulli.
J.H. Hecht, J.A. Weiner, S.R. Post, and J. Chun P. Bonaldo, D. Volpin, and G.M. Bressan
1085 Adenovirus-mediated gene transfer of the tumor 1179 Differential effects of parathyroid hormone
suppressor, p53, induces apoptosis in fragments on collagen gene expression in
postmitotic neurons. chondrocytes.
R.S. Slack, D.J. Belliveau, M. Rosenberg, J. Atwal, S. Erdmann, W. Muller, S. Bahrami. S.I. Vornehm,
H. Lochmiiller, R. Aloyz, A. Haghighi, B. Lach, H. Mayer, P. Bruckner, K. von der Mark,
P. Seth, E. Cooper, and F.D. Miller and H. Burkhardt
1097 Healing of incisional wounds in the embryonic 1193 ADDITIONS AND CORRECTIONS
chick wing bud: Characterization of the actin
purse-string and demonstration of a requirement
for Rho activation.
J. Brock, K. Midwinter, J. Lewis, and P. Martin
1109 Identification of LIM3 as the principal
determinant of paxillin focal adhesion
localization and characterization of a novel motif
on paxillin directing vinculin and focal adhesion
kinase binding.
M.C. Brown, J.A. Perrotta, and C.E. Turner
Volume 135, Number 5, December 1996
1195 Active and inactive genes localize preferentially 1229 The refolding activity of the yeast heat shock
in the periphery of chromosome territories. proteins Ssal and Ssa2 defines their role in
A. Kurz, S. Lampel, J.E. Nickolenko, J. BradI, protein translocation.
A. Benner, R.M. Zirbel, T. Cremer, and P. Lichter G.L. Bush and D.I. Meyer
1239 A major transmembrane protein of Golgi-derived
1207 Chromosome architecture can dictate site-specific COPI-coated vesicles involved in coatomer
initiation of DNA replication in Xenopus egg binding.
extracts.
K. Sohn. L. Orci, M. Ravazzola, M. Amherdt.
S.J. Lawlis, S.M. Keezer, J.-R. Wu, and D.M. Gilbert M. Bremser, F. Lottspeich. K. Fiedler, J.B. Helms,
and F.T. Wieland
1219 Phosphorylation of linker histone is associated 1249 A role for phosphoinositide 3-kinase in the
with transcriptional activation in a normally completion of macropinocytosis and phagocytosis
silent nucleus. by macrophages.
M.T. Sweet, K. Jones, and C.D. Allis N. Araki, M.T. Johnson, and J.A. Swanson
1261 The isoforms of proprotein convertase PCS are 1369 Presence of double-strand breaks with single-base
sorted to different subcellular compartments. 3' overhangs in cells undergoing apoptosis but
I. De Bie, M. Marcinkiewicz, D. Malide, C. Lazure, not necrosis.
K. Nakayama, M. Bendayan, and N.G. Seidah V.V. Didenko and P.J. Hornsby
1277 Roles for Racl and Cdc42 in planar polarization 1377 A role for Jun-N-terminal kinase in anoikis;
and hair outgrowth in the wing of Drosophila. suppression by bcl-2 and crmA.
S. Eaton, R. Wepf, and K. Simons S.M. Frisch, K. Vuori, D. Kelaita, and S. Sicks
1291 F-Actin bundles in Drosophila bristles are 1383 Inhibition of ppl25’^''‘^ in cultured fibroblasts
assembled from modules composed of short results in apoptosis.
filaments.
J.E. Hungerford, M.T. Compton, M.L. Matter,
L. G. Tilney, P. Connelly, S. Smith, and G.M. Guild B.G. Hoffstrom, and C.A. Otey
1309 Bundling of actin filaments by elongation factor 1391 Translation of CUG- but not AUG-initiated
1 a inhibits polymerization at filament ends. forms of human fibroblast growth factor 2 is
J. W. Murray, B.T. Edmonds, G. Liu, and J. Condeelis activated in transformed and stressed cells.
S. Vagner, C. Touriol, B. Galy, S. Audigier,
1323 MHPl, an essential gene in Saccharomyces
M.-C. Gensac, F. Amalric, F. Bayard, H. Prats,
cerevisiae required for microtubule function. and A.-C. Prats
I. Irminger-Finger, E. Hurt, A. Roebuck, M.A. Collart,
1403 Molecular and functional defects in kidneys of
and S.J. Edelstein
mice lacking collagen a3(IV): Implications for
1341 Genetic and metabolic status of NGF-deprived alport syndrome.
sympathetic neurons saved by an inhibitor of
J.H. Miner and J.R. Sanes
ICE family proteases.
1415 Reduction of type V collagen using a
M. Deshmukh, J. Vasilakos, T.L. Deckwerth.
P.A. Lampe, B.D. Shivers, and E.M. Johnson, Jr. dominant-negative strategy alters the regulation
of fibrillogenesis and results in the loss of
1355 Molecular composition of the node of Ranvier: comeal-specific fibril morphology.
Identification of ankyrin-binding cell adhesion
J.K. Marchant, R.A. Hahn, T.F. Linsenmayer,
molecules neurofascin (mucin+Zthird FNIII
and D.E. Birk
domain—) and NrCAM at nodal axon segments.
J. Q. Davis, S. Lambert, and V. Bennett
Volume 135, Number 6, Part 1, December 1996
1427 Three-dimensional reconstruction of painted 1485 A novel fluorescence-activated cell sorter-based
human interphase chromosomes: Active and screen for yeast endocytosis mutants identifies a
inactive X chromosome territories have similar yeast homologue of mammalian epslS.
volumes but differ in shape and surface B. Wendland, J.M. McCaffery, Q. Xiao,
stmcture. and S.D. Emr
R. Fils, S. Dietzel, E. Bertin, E. Schrbck, 1501 A role for N-myristoylation in protein targeting:
M.R. Speicher, T. Ried, M. Robert-Nicoud, C. Cremer,
NADH-cytochrome 65 reductase requires myristic
and T. Cremer
acid for association with outer mitochondrial but
1441 Lamin proteolysis facilitates nuclear events not ER membranes.
during apoptosis.
N. Borgese, D. Aggujaro, P. Carrera, G. Pietrini,
L. Rao, D. Perez, and E. White and M. Bassetti
1457 A novel ubiquitin-like modiflcation modulates 1515 Exclusion of CD45 inhibits activity of p56'^'‘
the partitioning of the Ran-GTPase-activating associated with glycolipid-enriched membrane
protein RanGAPl between the cytosol and the domains.
nuclear pore complex. W. Rodgers and J.K. Rose
M. J. Matunis, E. Coutavas, and G. Blobel
1525 a-Tubulin limits its own synthesis: Evidence for
1471 Formation of nascent secretory vesicles from the a mechanism involving translational repression.
tran.y-Golgi network of endocrine cells is M.L. Gonzalez-Garay and F. Cabral
inhibited by tyrosine kinase and phosphatase
inhibitors.
C.D. Austin and D. Shields
viii
1535 Actin and myosin function in directed vacuole 1619 Identification of a cytoplasmic domain important
movement during cell division in Saccharomyces in the polarized expression and clustering of the
cerevisiae. Kv2.1 channel.
K.L. Hill, N.L. Catlett, and L.S, Weisman R. H. Scannevin, H. Murakoshi, K.J. Rhodes,
and J.S. Trimmer
1551 Translocation of Src kinase to the celt periphery
is mediated by the actin cytoskeleton under the 1633 Integrins can collaborate with growth factors for
control of the Rho family of small G proteins. phosphorylation of receptor tyrosine kinases and
MAP kinase activation: Roles of integrin
V.J, Fincham, M. Unlu, V.G, Brunton, J.D. Pitts,
J.A. Wyke, and M.C. Frame aggregation and occupancy of receptors.
S. Miyamoto, H. Teramoto, J.S. Gutkind,
1565 Functional N-methyl-D-aspartate receptors in
and K.M. Yamada
0-2A glial precursor cells: A critical role in
regulating polysialic acid-neural cell adhesion 1643 Expression of N-cadherin by human squamous
molecule expression and cell migration. carcinoma cells induces a scattered fibroblastic
phenotype with disrupted cell-cell adhesion.
C. Wang, W,-F, Pralong, M.-F, Schulz, G. Rougon,
J.-M. Aubry, S. Pagliusi, A. Robert, and J.Z. Kiss S. Islam, T.E. Carey, G.T. Wolf, M.J. Wheelock,
and K.R. Johnson
1583 Native chick laminin-4 containing the |32 chain
(s-laminin) promotes motor axon growth. 1655 HEMCAM, an adhesion molecule expressed by
c-kit^ hemopoietic progenitors.
R. Brandenberger, R.A. Kammerer, J. Engel,
and M. Chiquet O. Vainio, D. Dunon, F. Aissi, J.-P. Dangy,
K.M. McNagny, and B.A. Imhof
1593 Cell adhesion molecules NgCAM and axonin-1
form heterodimers in the neuronal membrane 1669 Rescue of mammay epithelial cell apoptosis and
and cooperate in neurite outgrowth promotion. entactin degradation by a tissue inhibitor of
metalloproteinase-1 transgene.
A. Buchstaller, S. Kunz, P. Berger, B. Kunz,
U. Ziegler, C. Rader, and P. Sonderegger C.M. Alexander, E.W. Howard, M.J, Bissell,
and Z. Werb
1609 Angiotensin II regulation of neuromodulation:
Downstream signaling mechanism from 1679 ADDITIONS AND CORRECTIONS
activation of mitogen-activated protein kinase.
D. Lu. H. Yang, and M.K. Raizada
Volume 135, Number 6, Part 2, December 1996
Mini-Review 1727 Cell fusion during yeast mating requires high
1681 Polo kinase: The choreographer of the mitotic levels of a-factor mating pheromone.
stage? V. Brizzio, A.E. Gammie, G. Nijbroek, S. Michaelis,
and M.D. Rose
D.M. Glover, H. Ohkura, and A. Tavares
1741 Involvement of Rabphilin-3A in cortical granule
Regular Articles
exocytosis in mouse eggs.
1685 In vivo localization of DNA sequences and
N. Masumoto, T. Sasaki, M. Tahara, A. Mammoto,
visualization of large-scale chromatin
Y, Ikebuchi, K. Tasaka, M. Tokunaga, Y. Takai,
organization using lac operator/repressor and A. Miyake
recognition.
1749 Transferrin receptor containing the SDYQRL
C.C. Robinett. A. Straight, G. Li, C, Willhelm,
motif of TGN38 causes a reorganization of the
G. Sudlow, A. Murray, and A.S. Belmont
recycling compartment but is not targeted to the
1701 Antibody microinjection reveals an essential role TGN.
for human polo-like kinase 1 (Plkl) in the
A.O. Johnson, R.N, Ghosh, K.W. Dunn, R. Garippa,
functional maturation of mitotic centrosomes. J, Park, S. Mayor, F.R. Maxfield, and T.E. McGraw
H. A. Lane and E.A. Nigg
1763 Multiple PEX genes are required for proper
1715 Targeting of membranes to sea urchin sperm subcellular distribution and stability of PexSp,
chromatin is mediated by a lamin B receptor-like the PTSl receptor: Evidence that PTSl protein
integral membrane protein. import is mediated by a cycling receptor.
P. Collas. J.-C. Courvalin, and D. Poccia G. Dodf and S.J. Gould
IX
1775 Granule lattice protein 1 (Grllp), an acidic, 1867 Membrane topology of the high-affinity
calcium-binding protein in Tetrahymena L-giutamate transporter (GLAST-1) of the
thermophila dense-core secretory granules, central nervous system.
influences granule size, shape, content S. Wahle and W. Stoffel
organization, and release but not protein sorting
1879 Regulation of epidermal differentiation by a
or condensation.
Distal-less homeodomain gene.
N.D. Chilcoat, S.M. Melia. A. Haddad,
and A.P. Turkewitz M.I. Morasso, N.G. Markova, and T.D. Sargent
1789 The sequence NPFXD deflnes a new class of 1889 Treatment of melanoma cells with the synthetic
endocytosis signal in Saccharomyces cerevisiae. retinoid CD437 induces apoptosis via activation
of AP-1 in vitro, and causes growth inhibition in
P.K. Tan, J.P. Howard, and G.S. Payne
xenografts in vivo.
1801 AP-2-containing clathrin coats assemble on
D. Schadendorf, M.A. Kern, M. Artuc, H.L. Pahl,
mature lysosomes. T. Rosenbach, I. Fichtner, W. Nurnberg, S. Stilting,
L. M. Traub, S.I. Bannykh, J.E. Rodel, M. Aridor, E. v. Stebut. M. Worm, A. Makki, K. Jurgovsky,
W.E. Balch, and S. Komfeld G. Kolde, and B.M. Henz
1815 Centractin (ARPl) associates with spectrin 1899 Quantitative analysis of cadherin-catenin-actin
revealing a potential mechanism to link dynactin reorganization during development of cell-cell
to intracellular organelles. adhesion.
E.A. Holleran, M.K. Tokito, S. Karki, C.L. Adams, W.J. Nelson, and S.J. Smith
and E.L.F. Holzbaur
1913 Calreticulin modulates cell adhesiveness via
1831 The initial fusion pore induced by baculovirus regulation of vinculin expression.
GP64 is large and forms quickly. M. Opas, M. Szewczenko-Pawlikowski, G.K. Jass,
1. Plonsky and J. Zimmerberg N. Mesaeli, and M. Michalak
1841 Targeting of moloney murine leukemia virus gag 1925 ADDITIONS AND CORRECTIONS
precursor to the site of virus budding.
1927 AUTHOR INDEX FOR VOLUMES 132-135
M. Suomalainen, K. Hultenby, and H. Garoff
1953 SUBJECT INDEX FOR VOLUMES 132-135
1853 The sup-pf-2 mutations of Chlamydomonas alter
the activity of the outer dynein arms by 1983 ACKNOWLEDGMENT
modification of the y-dynein heavy chain.
G. Rupp, E. O’Toole, L.C. Gardner, B.F. Mitchell,
and M.E. Porter