Table Of Content

AUTHOR INDEX Volume 63 • 1993 Abe, A. and Karaki, H. Higo, K. and Karasawa, A. Vasodilation by db-cAMP and okadaic acid 129 Antithrombotic effect of KW-3635 521 Abe, H. See Zhenjiu, W. Hirayama, Y. See Kobayashi, K. Adachi, H. See Marumo, T. Hiroi, J. See Kobayashi, K. Adachi, N. See Oishi, R. Hirouchi, Y., Naganuma, H., Kawahara, Y., Okada, R., Akahane, M. See Yamazaki, Yoshinobu Kamiya, A., Inui, K. and Hori, R. Akai, T. See Mizokawa, T. Effect of NAAs on CER nephrotoxicity 487 Amano, M., Hasegawa, M., Hasegawa, T. and Nabeshima, T. Honda, K. See Yazawa, H. Learning and memory in ischemic gerbils 469 - See Yuki, H. Arai, K. See Matsuura, A. Honma, Y. See Yazawa, H. Araki, T. See Kinbara, S. Hori, R. See Hirouchi, Y. Asakura, R. See Matsuura, A. Hoshiko, K. and Morley, J. Asakura, W., Matsumoto, K., Ohta, H. and Watanabe, H. Allergic airway hyperreactivity 151 Deprivation and antidepressants 455 Salbutamol and airway hyperreactivity 159 Ashikawa, N. See Matsuura, A. Ashizawa, N. See Matsuura, A. Ichikawa, S. See Kishibayashi, N. Awaji, T. See Zhenjiu, W. lida-Kubota, E. See Yazawa, H. lizuka, K. See Yamazaki, Yoshinobu Chihara, S. See Kobayashi, K. Imai, T. See Kobayashi, K. Inaba, K. See Haga, K. Endoh, M., Norota, 1., Takanashi, M. and Kasai, H. Inagaki, M. See Izumi, J. Protein kinase C and cardiac inotropy 17 fnagaki, N. See Nagai, H. Esumi, H. See Marumo, T. Inatomi, N., Satoh, T., Satoh, H., Itoh, Z. and Omura, S. Etoh, Y., Miyazaki, M., Saitoh, Hiroshi and Toda, N. EM523 on gastrointestinal motility 209 Human renin inhibitor, KRI-1314 109 Inazu, N. and Fujii, T. Testis carbonyl reductase and calcium ion 65 Fujihara, A. See Yuki, H. Inoki, R. See Yonehara, N. Fujii, T. See Inazu, N. Inui, K. See Hirouchi, Y. Fukami, K., Itagaki, M., Komori, S. and Ohashi, H. Ishida, R. See Ogiku, N. Ca^^ release-mediated contractions 171 Ishii, A. See Kishibayashi, N. Fukata, Y. See Harada, K. - See Tomaru, A. Fukata, Y., Kaneta, S., Okada, Y., Yokoyama, T., Jinno, Y., Ishizaki, K. See Kinbara, S. Fukushima, H. and Ogawa, N. Ishizuka, H. See Tanabe, M. KRN2391 and coronary vascular bed 305 Itagaki, M. See Fukami, K. Fukuda, T. See Haga, K. Ito, H. See Yuki, H. Fukushima, H. See Fukata, Y. Itoh, Y. See Oishi, R. - See Harada, K. Itoh, Z. See Inatomi, N. Iwama, T. See Nagai, H. Goto, T. See Kanashiro, M. Iwao, H. See Yamanaka, S. Gushima, H. See Kawasaki, T. Iwata, N. See Tanabe, M. Izumi, J., Inagaki, M., Kiuchi, Y., Matsumoto, M., Haga, K., Inaba, K., Shoji, H., Morimoto, Y., Fukuda, T. and Yamazaki, Yukako, Morioka, D., Usami, S. and Oguchi, K. Setoguchi, M. Ischemia and brain monoamines in gerbils 143 Antiemetic effects of Y-25130 377 Hamada, K., Nakajima, Y., Nirei, H., Nakajima, C., Jinkawa, M. See Kontani, H. Nagashima, A., Sogabe, K., Notsu, Y. and Ono, T. Jinno, Y. See Fukata, Y. Antihypertensive effect and FK 739 335 Harada, K., Fukata, Y., Miwa, A., Kaneta, S., Fukushima, H. and Kaku, S. See Kawasaki, T. Ogawa, N. Kamato, T. See Yuki, H. Antianginal effect of KRN2391 35 Kamiya, A. See Hirouchi, Y. Hasan, S. See Mizokawa, T. Kanashiro, M., Matsubara, T., Goto, T. and Sakamoto, N. Hasegawa, M. See Amano, M. CLA reduces reperfusion-induced VF 47 Hasegawa, T. See Amano, M. Kanda, A. and Hashimoto, H. - See Yamada, K. Antihypertensive effects of semotiadil 121 Hashimoto, H. See Kanda, A. Kaneko, T. See Tanabe, M. Hashimoto, K. See Zhenjiu, W. Kaneta, S. See Fukata, Y. Hashimoto, Y. See Ohmi, K. - See Harada, K. Hatakeyama, Y., Matsuo, M., Tomoi, M., Mori, J. and Kaneto, H. See Rahman, A.F.M.M. Kohsaka, M. Karaki, H. See Abe, A. Gastric protection and mediators 251 Karasawa, A. See Higo, K. AUTHOR INDEX Volume 63 • 1993 Abe, A. and Karaki, H. Higo, K. and Karasawa, A. Vasodilation by db-cAMP and okadaic acid 129 Antithrombotic effect of KW-3635 521 Abe, H. See Zhenjiu, W. Hirayama, Y. See Kobayashi, K. Adachi, H. See Marumo, T. Hiroi, J. See Kobayashi, K. Adachi, N. See Oishi, R. Hirouchi, Y., Naganuma, H., Kawahara, Y., Okada, R., Akahane, M. See Yamazaki, Yoshinobu Kamiya, A., Inui, K. and Hori, R. Akai, T. See Mizokawa, T. Effect of NAAs on CER nephrotoxicity 487 Amano, M., Hasegawa, M., Hasegawa, T. and Nabeshima, T. Honda, K. See Yazawa, H. Learning and memory in ischemic gerbils 469 - See Yuki, H. Arai, K. See Matsuura, A. Honma, Y. See Yazawa, H. Araki, T. See Kinbara, S. Hori, R. See Hirouchi, Y. Asakura, R. See Matsuura, A. Hoshiko, K. and Morley, J. Asakura, W., Matsumoto, K., Ohta, H. and Watanabe, H. Allergic airway hyperreactivity 151 Deprivation and antidepressants 455 Salbutamol and airway hyperreactivity 159 Ashikawa, N. See Matsuura, A. Ashizawa, N. See Matsuura, A. Ichikawa, S. See Kishibayashi, N. Awaji, T. See Zhenjiu, W. lida-Kubota, E. See Yazawa, H. lizuka, K. See Yamazaki, Yoshinobu Chihara, S. See Kobayashi, K. Imai, T. See Kobayashi, K. Inaba, K. See Haga, K. Endoh, M., Norota, 1., Takanashi, M. and Kasai, H. Inagaki, M. See Izumi, J. Protein kinase C and cardiac inotropy 17 fnagaki, N. See Nagai, H. Esumi, H. See Marumo, T. Inatomi, N., Satoh, T., Satoh, H., Itoh, Z. and Omura, S. Etoh, Y., Miyazaki, M., Saitoh, Hiroshi and Toda, N. EM523 on gastrointestinal motility 209 Human renin inhibitor, KRI-1314 109 Inazu, N. and Fujii, T. Testis carbonyl reductase and calcium ion 65 Fujihara, A. See Yuki, H. Inoki, R. See Yonehara, N. Fujii, T. See Inazu, N. Inui, K. See Hirouchi, Y. Fukami, K., Itagaki, M., Komori, S. and Ohashi, H. Ishida, R. See Ogiku, N. Ca^^ release-mediated contractions 171 Ishii, A. See Kishibayashi, N. Fukata, Y. See Harada, K. - See Tomaru, A. Fukata, Y., Kaneta, S., Okada, Y., Yokoyama, T., Jinno, Y., Ishizaki, K. See Kinbara, S. Fukushima, H. and Ogawa, N. Ishizuka, H. See Tanabe, M. KRN2391 and coronary vascular bed 305 Itagaki, M. See Fukami, K. Fukuda, T. See Haga, K. Ito, H. See Yuki, H. Fukushima, H. See Fukata, Y. Itoh, Y. See Oishi, R. - See Harada, K. Itoh, Z. See Inatomi, N. Iwama, T. See Nagai, H. Goto, T. See Kanashiro, M. Iwao, H. See Yamanaka, S. Gushima, H. See Kawasaki, T. Iwata, N. See Tanabe, M. Izumi, J., Inagaki, M., Kiuchi, Y., Matsumoto, M., Haga, K., Inaba, K., Shoji, H., Morimoto, Y., Fukuda, T. and Yamazaki, Yukako, Morioka, D., Usami, S. and Oguchi, K. Setoguchi, M. Ischemia and brain monoamines in gerbils 143 Antiemetic effects of Y-25130 377 Hamada, K., Nakajima, Y., Nirei, H., Nakajima, C., Jinkawa, M. See Kontani, H. Nagashima, A., Sogabe, K., Notsu, Y. and Ono, T. Jinno, Y. See Fukata, Y. Antihypertensive effect and FK 739 335 Harada, K., Fukata, Y., Miwa, A., Kaneta, S., Fukushima, H. and Kaku, S. See Kawasaki, T. Ogawa, N. Kamato, T. See Yuki, H. Antianginal effect of KRN2391 35 Kamiya, A. See Hirouchi, Y. Hasan, S. See Mizokawa, T. Kanashiro, M., Matsubara, T., Goto, T. and Sakamoto, N. Hasegawa, M. See Amano, M. CLA reduces reperfusion-induced VF 47 Hasegawa, T. See Amano, M. Kanda, A. and Hashimoto, H. - See Yamada, K. Antihypertensive effects of semotiadil 121 Hashimoto, H. See Kanda, A. Kaneko, T. See Tanabe, M. Hashimoto, K. See Zhenjiu, W. Kaneta, S. See Fukata, Y. Hashimoto, Y. See Ohmi, K. - See Harada, K. Hatakeyama, Y., Matsuo, M., Tomoi, M., Mori, J. and Kaneto, H. See Rahman, A.F.M.M. Kohsaka, M. Karaki, H. See Abe, A. Gastric protection and mediators 251 Karasawa, A. See Higo, K. Author Index vii Karasawa, A. See Kawakage, M. Kusaka, H. and Karasawa, A. - See Kishibayashi, N. Adenosine Apantagonist and tolerance 513 - See Kusaka, H. - See Mizumoto, H. Lacey, E. See Kawamura, 1. - See Mori, T. - See Tomaru, A. Manda, T. See Kawamura, 1. Kasai, H. See Endoh, M. Maniwa, T. See Qu, Y.-L. Kato, H. See Kurihara, J. Marumo, T., Nakaki, T., Adachi, H., Esumi, H., Suzuki, H., Kato, R. See Marumo, T. Saruta, T. and Kato, R. Kato, Y. See Shinkawa, T. Endothelial NO synthase mRNA 327 Katoh, M. See Kawasaki, T. Marumo, T., Nakaki, T., Nagata, Kiyoshi, Miyata, M., Adachi, H., Katoh, S. See Kawasaki, T. Esumi, H., Suzuki, H., Saruta, T. and Kato, R. Kawahara, Y. See Hirouchi, Y. Dexamethasone inhibits NO synthase mRNA induction 361 Kawai, C. See Kawasaki, T. Maruyama, T. See Tanabe, M. Kawakage, M., Mizumoto, H., Nukui, E., Sato, S. and Masukawa, T. and Nakanishi, K. Karasawa, A. Hypoxia-induced lethality 279 TXRA in murine lupus nephritis 433 Matsubara, T. See Kanashiro, M. Kawamura, I., Mizota, T., Lacey, E., Tanaka, Y., Manda, T., Matsuda, T. See Tsushima, H. Shimomura, K. and Kohsaka, M. Matsui, S. See Tojyo, Y. Droloxifene and human breast tumors 27 Matsuki, N. See Nagata, Koichi Kawamura, S. See Kawasaki, T. Matsumoto, K. See Asakura, W. Kawanishi, M. See Ohata, H. Matsumoto, M. See Izumi, J. Kawanishi, T. See Ohata, H. Matsumoto, Y. See Tojyo, Y. Kawasaki, H. See Nakamura, S. Matsuo, M. See Hatakeyama, Y. Kawasaki, T., Katoh, M., Kaku, S., Gushima, H., Takenaka, T., Matsuoka, Y., Sugioka, T., Terawaki, Y., Uruno, T. and Yui, Y. and Kawai, C. Kubota, K. Intracoronary thrombolysis with YM866 319 Antinociception by phenylethylamines 101 Thrombolytic activity of YM866 9 Matsuura, A., Okumura, H., Asakura, R., Ashizawa, N., Kawasaki, T., Kawamura, S., Katoh, S. and Takenaka, T. Takahashi, Mayumi, Kobayashi, F., Ashikawa, N. and Arai, K. Thrombosis model and YM866 135 Inhibition of ECE by aspergillomarasmines 187 Kim, S. See Yamanaka, S. Miura, K. See Yamanaka, S. Kimura, I. See Kobayashi, S. Miura, Y. See Kobayashi, S. Kimura, M. See Kobayashi, S. Miwa, A. See Harada, K. Kinbara, S., Ishizaki, K., Takeuchi, Y., Miyazawa, N. and Miyagishi, A. See Qu, Y.-L. Araki, T. Miyamoto, Y., Morita, N., Nakamura, N., Yamanishi, T., Hepatoprotective effect of UR-906 125 Kishioka, S. and Yamamoto, H. Kishi, Seiko See Yamaguchi, Masayoshi Effect of naloxone morphine concentration 235 Kishi, Shinichi See Kobayashi, K. Miyata, K. See Yuki, H. Kishibayashi, N. See Tomaru, A. Miyata, M. See Marumo, T. Kishibayashi, N., Ichikawa, S., Yokoyama, T., Ishii, A. and Miyazaki, M. See Etoh, Y. Karasawa, A. Miyazawa, N. See Kinbara, S. Colonic function of KF18259 495 Mizokawa, T., Akai, T., Nakada, Y., Yamaguchi, Motonori, Kishioka, S. See Miyamoto, Y. Nakagawa, H., Hasan, S., Rettig, K.-J. and Wachtel, H. Kitagaki, K. See Nagai, H. A new anti-hyperprolactinemic agent 269 Kitazawa, M. See Yamazaki, Yoshinobu Mizota, M. See Shinkawa, T. Kiuchi, Y. See Izumi, J. Mizota, T. See Kawamura, 1. Kobayashi, F. See Matsuura, A. Mizumoto, H. See Kawakage, M. Kobayashi, K., Hiroi, J., Kishi, Shinichi, Sawase, K., Mizumoto, H. and Karasawa, A. Hirayama, Y., Chihara, S., Imai, T., Shigi, Y., Antidiuresis of adenosine Ai-agonist 257 Shimomura, K. and Kohsaka, M. Momose, K. See Ohata, H. Antiallergic effects of quinotolast 73 Mori, J. See Hatakeyama, Y. Kobayashi, M. See Yamazaki, Yoshinobu Mori, M. See Tsushima, H. Kobayashi, S., Miura, Y., Naitoh, T., Kimura, 1. and Kimura, M. Mori, T., Moriyama, T. and Karasawa, A. Anti-competence of cnidium phthalides 353 Adenosine Apreceptor in the heart 265 Koda, A. See Nagai, H. Morimoto, Y. See Haga, K. Kohsaka, M. See Hatakeyama, Y. Morioka, D. See Izumi, J. - See Kawamura, I. Morita, N. See Miyamoto, Y. - See Kobayashi, K. Morita, S. See Yamada, K. Kokubu, N. See Satoh, M. Moriyama, T. See Mori, T. Komori, S. See Fukami, K. Morley, J. See Hoshiko, K. Kontani, H., Jinkawa, M. and Sakai, T. Motomura, S. See Zhenjiu, W. Levcromakalim on rat urinary tract 503 Kubota, K. See Matsuoka, Y. Nabeshima, T. See Amano, M. Kurashina, Y. See Yamazaki, Yoshinobu - See Yamada, K. Kurihara, J., Tamaoki, S. and Kato, H. Nagai, H., Sakurai, T., Iwama, T., Yamaguchi, S., Kitagaki, K., Baroreflex modulation and cerebral ischemia 111 Inagaki, N. and Koda, A. viii Author Index Anti-allergic action of MKS-492 405 Sakitama, K. Nagano, M. See Tanabe, M. Muscle relaxants on flexor reflex 369 Naganuma, H. See Hirouchi, Y. Sakurai, T. See Nagai, H. Nagashitna, A. See Hamada, K. Saruta, T. See Marumo, T. Nagata, Kiyoshi See Marumo, T. Sasa, M. See Tsuru, H. Nagata, Koichi, Saito, Hiroshi and Matsuki, N. Sasahara, K. See Tanabe, M. Purinergic effects in suncus ileum 415 Sato, S. See Kawakage, M. Nagatomo, T. See Qu, Y.-L. Satoh, H. See Inatomi, N. Naitoh, T. See Kobayashi, S. Satoh, M., Kokubu, N. and Takayanagi, I. Nakada, Y. See Mizokawa, T. OTP^-'S and chloroethylclonidine 1 Nakagawa, H. See Mizokawa, T. Satoh, T. See Inatomi, N. Nakajima, C. See Hamada, K. Sawase, K. See Kobayashi, K. Nakajima, Y. See Hamada, K. Setoguchi, M. See Haga, K. Nakaki, T. See Marumo, T. Shigi, Y. See Kobayashi, K. Nakamura, N. See Miyamoto, Y. Shimomura, K. See Kawamura, I. Nakamura, S., Kawasaki, H. and Takasaki, K. - See Kobayashi, K. Brain vasopressin and clonidine 447 Shinkawa, T., Kato, Y., Tsuchiya, N., Yamasaki, F., Nakanishi, K. See Masukawa, T. Uemura, A. and Mizota, M. Narita, M. See Takeuchi, K. Beneficial effect of M17055 on SHR 241 Negita, S. See Tsuru, H. Shoji, H. See Haga, K. Nirei, H. See Hamada, K. Sogabe, K. See Hamada, K. Nishida, A. See Yuki, H. Sugioka, T. See Matsuoka, Y. Nishio, A. See Obi, T. Sugiyama, K. See Qu, Y.-L. Nonomura, Y. See Ohmi, K. Sumikawa, H. See Ogiku, N. Norota, 1. See Endoh, M. Suzuki, F. See Obi, T. Notsu, Y. See Hamada, K. Suzuki, H. See Marumo, T. Nukui, E. See Kawakage, M. Takahashi, Masakatsu See Rahman, A.F.M.M. Obi, T., Suzuki, F. and Nishio, A. Takahashi, Mayumi See Matsuura, A. L-Nitro-arginine insensitive relaxation 391 Takahashi, Michihito See Ohata, H. Ogawa, N. See Fukata, Y. Takanashi, M. See Endoh, M. - See Harada, K. Takasaki, K. See Nakamura, S. Ogiku, N., Sumikawa, H. and Ishida, R. Takayanagi, 1. See Satoh, M. Imidapril on sympathetic nervous system 295 Takeda, M. See Yuki, H. Oguchi, K. See Izumi, J. Takenaka, T. See Kawasaki, T. Ohashi, H. See Fukami, K. Takeuchi, K., Ohuchi, T., Narita, M. and Okabe, S. Ohata, H., Kawanishi, T., Kawanishi, M., Uneyama, C., Sensory neurons on gastric mucosal integrity 479 Takahashi, Michihito and Momose, K. Takeuchi, Y. See Kinbara, S. Spontaneous [Ca^"^]! oscillation 83 Tamaoki, S. See Kurihara, J. Ohmi, K., Yamashita, S., Hashimoto, Y. and Nonomura, Y. Tanabe, M., Ishizuka, H., Maruyama, T., Kaneko, T., Function of giant endothelial cells 195 Tonohiro, T., Sakai, J., Nagano, M., Sasahara, K. and Ohta, H. See Asakura, W. Iwata, N. Ohuchi, T. See Takeuchi, K. Muscle relaxant action of CS-722 385 Oishi, R., Itoh, Y., Adachi, N. and Saeki, K. Tanaka, Y. See Kawamura, I. MCl-225 and brain monoamine metabolism 261 Tang, F.-D. See Yonehara, N. Okabe, S. See Takeuchi, K. Tanimura, A. See Tojyo, Y. Okada, R. See Hirouchi, Y. Teranishi, Y. See Tsuru, H. Okada, Y. See Fukata, Y. Teraoka, T. See Yamada, K. Okumura, H. See Matsuura, A. Terawaki, Y. See Matsuoka, Y. Omura, S. See Inatomi, N. Toda, N. See Etoh, Y. Ono, T. See Hamada, K. Tojyo, Y., Tanimura, A., Matsui, S. and Matsumoto, Y. K'*' release and [Ca^"*^]! in parotid acini 439 Qu, Y.-L., Sugiyama, K., Nagatomo, T., Maniwa, T. and Tomaru, A., Ishii, A., Kishibayashi, N. and Karasawa, A. Miyagishi, A. Giant migrating contractions in rats 525 Ca^"*^ antagonism of SM-6586 165 Tomoi, M. See Hatakeyama, Y. Tonohiro, T. See Tanabe, M. Rahman, A.F.M.M., Takahashi, Masakatsu and Kaneto, H. Tsuchiya, N. See Shinkawa, T. Nociception modifying morphine tolerance 59 Tsuru, H., Negita, S., Teranishi, Y. and Sasa, M. Rettig, K.-J. See Mizokawa, T. Transmitter release in decentralized artery 285 Tsushima, H., Mori, M. and Matsuda, T. Saeki, K. See Oishi, R. Effects of DADL in the SON and PVN 181 Saito, Hiroshi See Nagata, Koichi Antidiureses of DYN in the SON and PVN 461 Saitoh, Hiroshi See Etoh, Y. Sakai, J. See Tanabe, M. Uemura, A. See Shinkawa, T. Sakai, T. See Kontani, H. Uneyama, C. See Ohata, H. Sakamoto, N. See Kanashiro, M. Uruno, T. See Matsuoka, Y. Author Index IX Usami, S. See Izumi, J. A new CCK-A-receptor antagonist, KSG-504 219 Yamazaki, Yukako See Izumi, J. Wachtel, H. See Mizokawa, T. Yazawa, H., lida-Kubota, E., Honma, Y. and Honda, K. Watanabe, H. See Asakura, W. Endothelin receptor in HASMCs 313 Yokoyama, T. See Fukata, Y. Yamada, K., Teraoka, T., Morita, S., Hasegawa, T. and - See Kishibayashi, N. Nabeshima, T. Yonehara, N., Tang, F.-D. and Inoki, R. Calcium channels in the brain 423 Morphine and cutaneous blood flow S3 Yamaguchi, Masayoshi and Kishi, Seiko Yui, Y. See Kawasaki, T. Effect of AHZ on bone loss 203 Yuki, H., Kamato, T., Nishida, A., Fujihara, A., Takeda, M. and Yamaguchi, Motonori See Mizokawa, T. Miyata, K. Yamaguchi, S. See Nagai, H. YM-14471, a new H2-receptor antagonist 345 Yamamoto, H. See Miyamoto, Y. Yuki, H., Miyata, K., Kamato, T., Nishida, A., Ito, H., Yamanaka, S., Iwao, H., Yukimura, T., Kim, S. and Miura, K. Takeda, M. and Honda, K. Effect of A/®-nitro-L-arginine on EVS 41 Histamine H2-receptor and wheal response 93 Yamanishi, T. See Miyamoto, Y. Yukimura, T. See Yamanaka, S. Yamasaki, F. See Shinkawa, T. Yamashita, S. See Ohmi, K. Zhenjiu, W., Awaji, T., Abe, H., Motomura, S. and Hashimoto, K. Yamazaki, Yoshinobu, Akahane, M., Kobayashi, M., OPC-18790 on ventricular tachycardia 399 Kitazawa, M., Kurashina, Y. and lizuka, K. SUBJECT INDEX Volume 63 • 1993 N-Acyl amino acid (NAA) 487 Chronic decentralization 285 pyrdine) 335 Adaptive cytoprotection 251 Chronic pain 59 Flexor reflex 369 Adenosine Apreceptor antagonist 257, 265, Cimetidine 345 Forced swimming test 455 513 Cisplatin 377 Free radical scavenger 47 apAdrenoceptor 17 Clomipramine 455 02-Adrenoceptor 101, 227 Clonidine 447 Gallbladder contraction 219 Afferent fiber (gioup II) 369 Cnidium rhizome-derived phthalide 353 Gastric acid secretion 345 Aging 65 Colon (rat) 525 Gastric injury 479 yS-Alanyl-L-histidinato zinc 203 Colonic propulsion 495 Giant migrating contraction 525 Ambient temperature 279 w-Conotoxin GVIA 423 Glibenclamide 305, 503 Aminophylline 405 Coronary artery (canine) 305 Glycerol 525 Amphetamine 101 Coronary artery (bovine) 391 GTPr-S 1 Angina pectoris 35 Coronary vasodilator 35 Guanosine 5'-[;'-thio]triphosphate (GTP^S) Angiotensin Il-receptor antagonist 335 Cromakalim 305 171 Animal model 399 CS-722 ((R)-4-chloro-2-(2-hydroxy-3-mor- Antiallergics 73 pholinopropyl)-5-phenyl-4-isoxazolin-3- Heart (isolated, rat) 47 Antidiuretic effect 181, 461 one hydrochloride) 385 Histamine 171 Antidromic stimulation 53 Cutaneous blood flow 53 Histamine H2-receptor 93 Antiemesis 377 Cyclic AMP 129 Histamine H2-receptor antagonist (novel) Antiestrogen drug 27 Cypridina luciferin analog 47 345 Anti-hyperprolactinemic agent 269 Cystometrogram 503 Histological examination 135 Antihypertensive effect 121 Cytosolic Ca^"^ concentration 439 5-HT3 receptor 377 Antihypertensive therapy 241 5-HT3-receptor antagonist 495 Antinociception 101 Decerebrate rigidity 385 Hyperlocomotion 469 Antinociceptive tolerance 59 Defecation 495 Hyperreactivity (airway) 151, 159 Antisympathetic effect 295 Desipramine 455 Hypertension 335 Antitumor 27 Dexamethasone 327, 361 Hypotensive effect 109 Aorta (human) 313 Diethyldithiocarbamate 279 Hypoxia-induced lethality 279 Arginine 41, 251, 391 Disulfiram 279 Aspergillomarasmine 187 Diuretic effect 257, 513 Imidapril 295 Atropine 415 Dopamine D2-agonist 269 Imipramine 455 Doxorubicin/cyclophosphamide 377 Immunochemistry 65 Baroreflex (vagal) 227 Droloxifene 27 Indomethacin 415 Basolateral membrane 487 Dynorphin 461 Interferon-j' 327 7V-Benzoyl-/3-alanine (NBBA) 487 Interleukin-la 361 Big endothelin-1 187 Ear artery (rabbit) 285 Ischemia (cerebral) 227, 469 Binding (in vivo) 235 ECG-change 35 Ischemia (transient forebrain, gerbil) 143 Bone metabolism 203 EDTA 187 Ischemia/reperfusion injury 47 Bromocriptin 269 Effective vascular stiffness 41 Bronchial asthma 405 Electrophysiology 265 Japanese monkey 109 Bronchoconstriction 151 EM523 (de(N-methyl)-Af-ethyl-8,9-anhydro- Bronchodilator 405 erythromycin A 6,9-hemiacetal) 209 K channel opener 35 Emetic action 269 release 439 Ca^^ antagonistic effect 165 Enalapril 295 K-252a 195 Ca^"* channel 165 Endothelial cell 195 Kidney 433 Ca^"^ influx 423 Endothelin 313 KRN2391 (7V-cyano-7V-(2-nitroxyethyl)-3- Ca^^ release 171 Endothelin converting enzyme 187 pyridinecarboximidamide monomethane- Calcium channel (N-type, L-type) 423 Endothelin receptor 313 sulfonate) 35, 305 Calcium ion 65 Endothelin-1 187 KSG-504 ((S)-arginium (/?)-4-[7V-(3-methoxy- Calcium oscillation 83 Endothelium-dependent relaxation (brady- propyl)-Af-pentylcarbamoly]-5-(2-naphthyl- Capsaicin-sensitive sensory nerve 479 kinin-induced) 391 sulfonyl) pentanoate monohydrate) 219 Carbachol 171 D-Ala^-D-Leu*-Enkephalin 181 KW-3635 (sodium (£)-ll-[2-(5,6-dimethyl-l- Carbonyl reductase 65 Erythromycin 209 benzimidazolyl)ethylidene]-6,11-dihydro- Cardiovascular hypertrophy 241 Extracellular noradrenaline concentration dibenz[b,e]oxepine-2-carboxylate monohy¬ CCK-A-receptor antagonist 219 261 drate) 433, 521 Central pressor response 447 KW-3902 (8-(noradamantan-3-yl)-1,3- Centrally acting muscle relaxant 369, 385 Famotidine 345 dipropylxanthine) 257, 265, 513 Cephaloridine (CER) 487 Femur (rat) 203 Chloroethylclonidine 1 FK 739 (2-butyl-3-[{2-(l//-tetrazol-5-yl)- Learning and memory 469 Cholestasis 125 biphenyl-4-yl}methyl]-3//-imidazo[4,5-b]- Levcromakalim 503 Subject Index XI Lipid peroxide 47 Ovariectomy 203 Squirrel monkey 93 Lipopolysaccharide 327, 361 Staurosporine 17 Local application 385 Pancreatic secretion 219 Striatum 143 Longitudinal muscle cell (cultured) 83 Paraventricular nucleus 181,461 Substance P 53 Loop diuretic 241 Parotid acini 439 Superoxide dismutase (brain) 279 Passive sensitization 151 Supraoptic nucleus 181, 461 M17055 (7-chloro-2,3-dihydro-l-(2-methyl- Patency status 135 Sympathetic neurotransmission 285 benzoyl)-4( 1 //)-quinolinone 4-oxime-O- Pharmacokinetics 235 sulfonic acid potassium salt) 241 Phenol red 27 Taurocholate 479 MCI-225 (4-(2-fluorophenyl)-6-methyl-2-( 1 - Phenylethanolamine 101 Tauroursodeoxycholate (UR-906) 125 piperazinyl)thieno[2,3-cnpyrimidine) 261 Phenylethylamine 101 Terguride 269 Mediator release inhibitor 73 Phorbol 12,13-dibutyrate 17 Testis 65 Microdialysis (brain) 143 Phorbol myristate acetate 391 Thapsigargin 83 Micturition 503 Phosphodiesterase type III inhibitor 405 Theophylline 415 Mild irritant 251 Platelet activating factor 151 Thoracic aorta (rabbit) 1 MKS-492 (/?[ + ]-8- {[ 1 -[3,4-dimethoxy- ’H-PN200-110 binding 165 Thrombi (aged) 9, 319 phenyl]-2-hydroxyethyl]amino}-3,7-dihy- Positive inotropic agent 399 Thrombolysis (carotid artery) 135 dro-7-[2-methoxyethyl]-1,3-dimethyl-1//- Positive inotropic effect 17 Thrombolysis (coronary artery) 9 purine-2,6-dione) 405 Prejunctional supersensitivity 285 Thrombolysis (intracoronary) 319 Mongolian gerbil 469 Primary culture 353 Thrombosis (copper coil-induced) 9 Monoamine metabolism 261 Prostaglandin 251 Thrombosis (electrically-induced) 135 Morphine 53, 59, 235 Prostaglandin F2„ 209 Thromboxane A2-receptor antagonist 433, Motilide 209 Protein kinase C 439 521 Motility 209 Protein kinase inhibitor 195 Tissue (rat) 165 Mucosal blood flow 479 Proximal tubular necrosis 487 Tissue renin-like activity 109 Muscarinic-cholinergic receptor 439 Purine nucleotide 415 Tissue-type plasminogen activator (t-PA) Purinoceptor 415 (modified) 9, 135, 319 NA 0345 17 Tolerance 513 Naloxone 53, 235 Quinotolast 73 Transmural nerve stimulation 285 a-Naphthylisothiocyanate (ANIT) 125 Tumor (human breast) 27 Neomycin 423 Recovery 479 Tumor necrosis factor-a 327, 361 Nephritis 433 REM sleep deprivation 455 Neuronal death (CAl) 469 Renal protective effect 513 Ureteral peristaltic function (rat) 503 Nicorandil 305 Renin inhibitor 109 Nitric oxide 41, 251, 391 Vasopressin 181, 461 Nitric oxide synthase mRNA 327, 361 Salbutamol 159 Vasopressin V^receptor antagonist 447 L-Nitro-arginine 391 Semotiadil 121 Venous tone 41 7V‘^-Nitro-L-arginine 41, 251 Senkyunolide H 353 Ventricular tachycardia 399 Nociceptive stimulant 59 Septum 227 Non-peptide antagonist 219 SM-6586 (methyl 1,4-dihydro-2,6-dimethyl- Wheal response 93 Noradrenaline 369 3-{3-(7V-benzyl-Mmethylaminomethyl)- Normethanephrine 143 1,2,4-oxadiazolyl-5-yl} -4-(3-nitrophenyl)- Y-25130 ((± )-N-( 1 -azabicyclo[2.2.2]oct-3- pyridine-5-carboxylate) 165 yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro- Okadaic acid 129 Smooth muscle (ileum) 171 2//-1,4-benzoxazine-8-carboxamide mono¬ OPC-18790 ((± )-6- [3-(3,4-dimethoxybenzyl- Smooth muscle (vascular) 129 hydrochloride) 377 amino)-2-hydroxypropoxy]-2( 1H)- Smooth muscle cell (human aorta) 313 YM-14471 (2-2 {- [2-(diaminomethylene- quinolinone) 399 Smooth muscle cell (mouse aorta) 353 amino)thiazol-4-yl]methylthio}ethyl-5-[3- Opiate receptor 235 Spinal reflex 385 (diethylamino)propyl]-6-methyl- Orally effective 109 Spontaneously hypertensive rat 121, 241 pyrimidine-4-one trihydrochloride) 345 Osteoporosis 203 Spontaneously hypertensive rat (pithed) 295