Austrian Society for Aerospace Medicine (ASM) (ed.) Health/rom Space Research Austrian Accomplishments Springer-Verlag Wien New York Sponsored by Austrian Ministry for Science and Research This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, reproduction by photocopying machine or similar means, and storage in data banks. © 1992 by Springer-VerJag/Wien Printed on acid-free paper With 103 Figures ISBN-13 :978-3-211-82413-9 e-ISBN-13 :978-3-7091-9260-3 DOl: 10.1007/978-3-7091-9260-3 Foreword Biomedical research is often done in a highly reductionistic way. Small subsystems are studied in artificial setups, and the results are hardly ap plicable to the system as a whole, e.g., humans adapting to an ever changing environment of high complexity. A recent analysis of physiol ogy's future, carried out by the APS-Long Range Planning Committee, arrives at the conclusion that" ... the next revolution in biological scien ces will be in the integrative-organismic area and requires bridges be tween highly specialized established subdisciplines which are sound on scientific and methodical grounds". Such integrative planning, hypo thesis testing, systems analysis, and validation can be boosted by ambi tious integrative research projects. The field of space life sciences and applied physiology can only flourish if high-profile scientific and operational cooperation can be maintained. Multi-center research entities are required which allow for coordinated planning and action. In order to start discussion along those lines on a European basis, a research group, dedicated to space biomedicine for more than a decade, organized and hosted the 1986 workshop, "European Space Medicine and Biology: Systems Analysis, Cooperation and Coordination (SPAMCO-meeting)", and the 1987 Third European Symposium on Life Sciences in Space in Graz, Austria. Another group established ties with Russian spaceflight physicians sev eral years ago. The extremely successful achievement of the first Aus trian manned space mission AUSTROMIR, both in terms of opera tional as well as technical and scientific aspects, represents a highlight within the frame of joint scientific activities in Austria. Spaceflight experiments are extremely expensive and cannot easi ly be repeated. It is therefore essential to arrive at outputs which are well accepted and recognized by the scientific community. Scientists who forge concepts for monitoring human physiology in complex and unusual situations must have access to a suitable infrastructure. The newly funded Austrian Society for Aerospace Medicine provides a ba- VI Foreword sis for multi-disciplinary approaches to spaceflight biomedical re search. Diagnostic, prognostic and elective, operational and preventive measures can be fostered by the activities ofthe Society. Examples are, e.g., health status monitoring, space sickness, crew compliance, waste management, food supply, ergonomics, or deconditioning counter measures. I am of the firm conviction that Austrian space life scientists have an important mission to pursue. Besides their research responsibilities, they are called upon to provide good arguments for continuation of the scientific treatment of global problems which are of concern to all of us. Earth is a great spaceship, with a unique life support system the func tioning of which seems to be jeopardized. Manned space flight chal lenges us with specific questions about life support in a hostile envi ronment. Learning from the right answers will also help us to better manage biomedical problems down on Earth. This booklet should be regarded as a documentation of recent work and provide an overview of concepts and capacities which should be employed on a national basis in the near future. I do hope that these concepts not only fit well into an international scientific frame but also will be the basis for continuing successful research activities. Vizekanzler Dr. Erhard Busek Bundesminister fiir Wissenschaft und Forschung July 1992 Foreword Space physiology and space medicine are comparatively new sciences and grew primarily out of the basic necessity to put man safely into space and bring him back again. It would however be incorrect to state that despite the years of experience gained by the main spacefaring na tions, each reaction of the human body exposed to the conditions of space is fully understood and recognized. Weightlessness and cosmic radiation are rather used as an exten sion of earthbound studies and can thus be considered as research tools. Most importantly, humans can be exposed to those physical environ mental conditions which can be neither adequately simulated nor re produced on Earth. As opposed to the traditional space sciences such as astrophysics, science in space has become an important branch in phys iology, biology and medicine worldwide. Some of its results have al ready had a beneficial impact on daily life. It can therefore be considered an outstanding achievement that a country like Austria, with no previous experience, was in a position to launch such an ambitious project as Austromir and carry it to a suc cessful conclusion. Comprising a total of ten individual experiments, in particular in the fields of neurophysiology, the cardiovascular and mus cular system, as well as genetics and radiation dosimetry, the life sciences by far outnumbered the other projects within the scientific part of the mission. It is difficult to predict what value the individual contri butions and results will have with regard to scientific success or prac tical use but one important aspect has to be kept in mind: as for all earthbound experiments and in particular for physiology, the quality will be measured in terms of reproducibility of results and their statisti cal validity. It is this factor which challenges the ingenuity and fantasy of the researcher, in particular when with the extremely small number of test subjects, rare flight opportunities and time and space constraints for both man and research equipment, the same results should be brought about. VIII Foreword These elements, especially when they are paired with international collaboration, lead to real progress and success in science and thus also to the success of a single mission. The coming years will confirm the need for and importance of continuing such a strategy. This applies to both the single investigations as well as to whole missions. As in any other branch of science, it is hoped that the initial investment fell on fruitful ground, that the scientists be kept motivated by further opportu nities and that their results be considered as building blocks within the overall scientific achievement. Last but not least, success should be measured in the same way as for any branch of science, in the long term, i.e. within a framework of many years of repeated experiments, bringing about the ultimate success. July 1992 Dr. med. H. Oser ESA HQ, Paris Austrian Society for Aerospace Medicine (ASM) ASM was established in 1991 and pursues the following aims: • To plan, coordinate and implement scientific research in the field of aerospace medicine and space life sciences on a national and inter national level. • To foster inter-disciplinary approaches. • To adapt instrumentation and methods employed in space medical research to terrestrial applications for medical diagnosis, therapy, prevention and rehabilitation. • To issue publications and provide information to the broad public concerning aerospace medicine and space life sciences. • To collaborate with partner institutions at home and abroad. Who is who in ASM: The committee presently consists of Prof. Dr. Franz Gerstenbrand, Innsbruck (president) Prof. Dr. Helmut Hinghofer-Szalkay, Graz (vice president) Prof. Dr. Norbert Bachl, Vienna (secretary general) Prof. Dipl.-Ing. Dr. Norbert Vana, Vienna (treasurer) Prof. Dipl.-Ing. Dr. Wolfgang Wehrmann, Vienna Dr. Wolf Friihauf, Vienna If you are interested in the activities of ASM, please write to: Austrian Society for Aerospace Medicine / Life Sciences in Space, Auf der Schmelz 6, A-11S0 Vienna, Austria. Contents Feichtinger Ch., Josseck B., Berzhatyi V., Batenchuk-Tusko T., Kozharinov V.: Acceptance-, Qualification-and Delivery Procedures for AUSTROMIR '91 Hardware .......................... . Harich H, Friedmann M., Kronke I.: Countdown for AUSTROMIR ................................................. 11 Persterer A., Berger M., Koppensteiner C, Muller C, Nefjodova M., Opitz M.: AUDIMIR - Directional Hearing at Microgravity .... ..... ....... .............. ......... ........... ....................... 21 HinghoJer-Szalkay H G., Konig E. M., Noskov N B., Sauseng-Fellegger G.: BODYFLUIDS .................................... 39 Benke Th., Koserenko 0., Gerstenbrand F.: COGIMIR - How to Measure Cognitive Functions in Space.... .......... ........ ........... 55 w., Vana N, Schoener Fugger M., Akatov J. A.: DOSIMIR - Radiation Measurements Inside the Soviet Space Station MIR ........................ ........ ........ ........ ......... 65 Gallasch E., Moser M., Kenner T., Kozlovskaya I., Konev A., Borisov M.: Experiment MIKROVIB - Investigation of Tremors in Microgravity .............. .......... .................... ........ ....... 85 Tuschl H, Klein W., Kovac R., Ott E., Chajdakow M. S., Voronkov Y. J.: Experiment MIRGEN ...................................... 109 Berger M., Gerstenbrand F., Kozlovskaya I. B., Burlatchkova N, Muigg A., Sokolov A., Babaev B., GrillI., Borisov M., DeCol C, Holzmuller G., Hochmair E., Steinwender G.: Eye, Head and Arm Coordination and Spinal Reflexes in Weightlessness - MONIMIR Experiment.. .......... .................... 119 XII Contents Bachl N., Baron R., Tschan H., Mossaheb M., Stockhammer H., w., Bumba Kozlovskaya I., Kharitonov K., Albrecht R., Hildebrand F., Witt M., Knauf M.: Development and Implementation of the MOTOMIR Experiment on the MIR Space Station ..................................................................... 137 Mueller Chr., Komilova L., Wiest G., Deecke L.: OPTOVERT Vertical Optokinetic Stimulation Used to Examine Central Orientational Processes ............................................................. 155 Moser M., Gallasch E., Rafolt D., Jerne} G., Kemp c., Moser-Kneffel E., Kenner T., Baevskij R., Funtowa I.: Cardiovascular Monitoring in Microgravity - The experiments PULSTRANS and SLEEP.. ...... ...... ............... 167 List of First Autors ... ......... ........ .......... ............ ..... ... ... ...... ............... 191