Genetic Influences on Human Fertility and Sexuality: Theoretical and Empirical Contributions from the Biological and Behavioral Sciences

334 Pages·2000·22.156 MB·English

by  Dean H. Hamer (auth.), Joseph Lee Rodgers, David C. Rowe, Warren B. Miller (eds.)

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GENETIC INFLUENCES ON HUMAN
FERTILITY AND SEXUALITY
Theoretical and Empirical Contributions
from the Biological and Behavioral
Sciences
edited by
J oseph Lee Rodgers
University of Oklahoma
David C. Rowe
University of Arizona
Warren B. Miller
Transnational Family Research Institute
SPRINGER SCIENCE+BUSINESS MEDIA, LLC
Library of Congress Cataloging-in-Publication Data
Genetic inf1uences on human fertility and sexuality: theoretical and empirical
contributions from the biological and behavioral sciences / edited by Joseph Lee
Rodgers, David C. Rowe, Warren B. Miller.
p ;cm.
lncludes bibliographical references and index.
ISBN 978-1-4613-7012-3 ISBN 978-1-4615-4467-8 (eBook)
DOI 10.1007/978-1-4615-4467-8
1. Fertility. 2. Human reproduction. 3. Human genetics. I. Rodgers, Joseph Lee. II.
Rowe, David C. III. Miller, Warren B., 1935-
[DNLM: 1. Fertility--genetics. 2. Genetics, Medical. 3. Reproduction--genetics. 4.
Sexuality. WP 565 G328 2000]
QP251 .G3532oo0
621.6--dc21
00-037111
Copyright © 2000 Springer Science+Business Media New York
Originally published by Kluwer Academic Publishers, New York in 2000
Softcover reprint ofthe hardcover Ist edition 2000
AII rights reserved. No part of this publication may be reproduced, stored in a
retrieval system or transmitted in any form or by any means, mechanical, photo
copying, recording, or otherwise, without the prior written permission of the publisher,
Springer Science+Business Media, LLC .
Printed on acid1ree paper.
CONTENTS
LISTOFCONTRIBUTORS ix
PREFACE ~
INTRODUCTIONI IntroductoryCommentsfroma BiologicalScientist 1
DeanH. Hamer
INTRODUCTIONIIIntroductoryCommentsfrom aSocialScientist 3
ChristineBachrach
PART I GENETICINFLUENCESON FERTILITY
MOTIVATIONAND FERTILITYOUTCOMES
CHAPTER1 EvolutionaryCausesofGeneticVariation In 7
Fertilityand OtherFitnessComponents
KimberlyA. Hughesand MaryH. Burleson
CHAPTER2 GeneticInfluencesonChildbearingMotivation: 35
FurtherTestingaTheoreticalFramework
WarrenB. Miller,DavidJ. Pasta,JamesMacMurray
DonnMuhleman,andDavidE.Comings
CHAPTER3 GeneticInfluencesonFertilityBehavior: Findings 67
FromaDanishTwinStudy,1910-1923
Hans-PeterKohlerandKaareChristensen
CHAPTER4 Geneticand EnvironmentalInfluencesonFertility 85
Expectationsand OutcomesusingNLSY Kinship
Data
JosephLeeRodgersandDebbyDoughty
CHAPTERS AHeritabilityStudyofChildbearingMotivation 107
DavidJ. PastaandWarrenB.Miller
COMMENTARY CommentaryonChapters1-5 121
J. RichardUdry
vi
PART II GENETICINFLUENCESONPUBERTAL
DEVELOPMENTANDREPRODUCTIVE
STRATEGIES
CHAPTER6 ConditionalandAlternativeReproductiveStrategies: 127
IndividualDifferencesinSusceptibilityto
RearingExperience
JayBelsky
CHAPTER7 Environmentaland GeneticInfluencesonPubertal 147
Development: EvolutionaryLifeHistoryTraits?
DavidC.Rowe
CHAPTERS BehaviorGeneticModelingofMenarcheinU.S. 169
Females
DebbyDoughtyWIdJosephLeeRodgers
CHAPTER9 EarlyFamilyEnvironment,ReproductiveStrategy, 183
and ContraceptiveBehavior: Testinga
GeneticHypothesis
Warren B. Miller& DavidJ. Pasta
COMMENTARY CommentaryonChapters6-9 231
LindaMealey
PART III GENETICINFLUENCESONSEXUALITY,
MARRIAGE,ANDREPRODUCTION
CHAPTER10 TheGeneticsofHumanSexualOrientation 237
Khytarn DawoodWIdJ. MichaelBailey
CHAPTER11 Endophenotypesfor MaritalStatus 253
intheNAS-NRCTwinRegistry
SUSWlL.TrombettaWId IrvingI.GottesmWl
CHAPTER12 Ageat FirstChildbirth: AMajorSelective 271
FactorforPsychiatricGenesintheTwentieth
Century
DavidE.Comings
vii
CHAPTER13 Twinning,Fertility,andtheOpportunityforNatw-al 289
Selectionina MicronesianIslandPopulation
JaneUnderwood
CHAPTER14 AssociationsbetweentheEndothelialNitricOxide 303
SynthaseGene(NOSJ),Reproductive Behaviors,
andTwinning
JamesMacMurray,BruceKovacs,MattMcGue,
JamesP.Johnson, HezekiahBlake,and
DavidE.Comings
COMMENTARY CommentaryonChapters10-14 317
A. J. Figueredo
INDEX 325
CONTRIBUTORS
ChristineBachrach, DemographicandBehavioral Sciences Branch,
Centerfor PopulationResearch,NICHD, 610 ExecutiveBlvd,
Room 8B13, BethesdaMD20892, [email protected]
1. Michael Bailey, DepartmentofPsychology, Northwestern University,
2029 Sheridan Road, Evanston, IL60208-2710,jm:J?IDJ~y.@my!!&d_\!
JayBelsky, DepartmentofPsychology, BirkbeckCollege,
UniversityofLondon, Malet Street, LondonWClE 7HX,
UnitedKingdom, [email protected]
HezekiahBlake, 4136 Alabama St., San Diego, Ca, 92104,
[email protected]
MaryH. Burleson, DepartmentofSocial and Behavioral Sciences
(MC 3051), ArizonaStateUniversityWest, P.O. Box37100,
Phoenix, AZ85069,M.mY.J~wl~~Qn@~~_\!,_~.d.\!
KaareChristensen, Epidemiology, InstituteofPublicHealth,
UniversityofSouthern Denmark: MaincampusOdenseUniversity,
Winsloewparken 17,DK-5000 OdenseC, Denmark,
[email protected]
DavidE. Comings, DepartmentofMedicalGenetics,
CityofHopeMedical Center, Duarte, CA91010,
[email protected]
Khytam Dawood, DepartmentofPsychology, Northwestern University,
2029 Sheridan Road, Evanston, IL 60208-2710, [email protected]
DebbyDoughty, DepartmentofPsychology, UniversityofOklahoma,
NormanOK 73019, [email protected]
A. 1. Figueredo, DepartmentofPsychology, UniversityofArizona,
Tucson, AZ85721, [email protected]
IrvingI. Gottesman, DepartmentofPsychology, UniversityofVirginia,
GilmerHall, Charlottesville VA22903, [email protected]
x
Dean H. Hamer, LaboratoryofBiochemistry,National CancerInstitute,
National InstituesofHealth, Bethesda, MD 20892,
[email protected]
Kimberly A. Hughes, DepartmentofLife Sciences (MC 2352),
Arizona StateUniversityWest, P.O. Box 27100, Phoenix, AZ 85069
Kim.l?~r.ly.1I"ygI1~~i@~.~.Y,.~.Y
PatrickJohnson, PsychiatryService(116Al),
Pettis Memorial Veterans Administration Medical Center,
LornaLinda, Ca, 92357, [email protected]
Hans-PeterKohler, Max Planck InstituteforDemographicResearch
Doberaner Str. 114, 18057Rostock, Germany, [email protected]
BruceKovacs, DepartmentofOB/GYN, roomSK-40, Universityof
SouthernCalifornia, LAC & USC women's& Children'sHospital,
1240N. Mission Ave, Los Angeles, CA90033,
[email protected]
IrvingI. Gottesman, DepartmentofPsychology, UniversityofVirginia,
GilmerHall, Charlottesville VA22903, j.ig@yjr.&!n.j~,!!g!!
James MacMurray, VicePresident, GenomicsDivision,
Medical Genetics, Inc., 1115No. Yale Ave, Claremont, CA91711,
[email protected]
MattMcGue, DepartmentofPsychology,UniversityofMinnesota,
ElliottHall, rmN460, 75 EastRiverRoad, Minneapolis, MN
55455-9991, [email protected]~_,p~j'.l;.b...!J_m.I.L~g.y
LindaMealey, PsychologyDepartment, CollegeofSt. Benedict,
St. Joseph, MN 56374, [email protected]
Warren B. Miller, Transnational FamilyResearch Institute,
355 WestOliveAvenue, Suite207, Sunnyvale, CA94086-7660,
[email protected]
Donn Muhleman, Department of Medical Genetics, City of Hope
MedicalCenter, Duarte, CA91010, [email protected].
xi
David1. Pasta, P.O. Box 881, PaloAlto, CA94302,QP.~~~@J.~lY.!n,Wm
Joseph LeeRodgers, DepartmentofPsychology,Universityof
Oklahoma, NormanOK73019, [email protected]
DavidC. Rowe, DivisionofFamilyStudies, 210 FCRBuilding,
UniversityofArizona, Tucson, AZ 85721 [email protected]
SusanTrombetta, DepartmentofPsychology, Box219 VassarCollege,
124Raymond Ave., Poughkeepsie, NY 12604-0219
[email protected]
1. RichardUdry,CarolinaPopulationCenter, University Square,
CB#8120, UNC-CH, ChapelHill,NC 27599, [email protected]
Jane H. Underwood, DepartmentofAnthropology,
UniversityofArizona, 2228 East4thStreet, Tucson, AZ 85719
[email protected]
PREFACE
We hope that the publication ofthis volume signals the beginning ofa
new and active research agenda, an agenda focused on the link between
genes and human reproduction. Such research will necessarily be
characterized by two important"I words": Integrative andInterdisciplinary.
There have certainly been individual scientists in the past who have
considered whether genetic influences can and do influence fertility and
other fitness traits. But there has been little integrative, interdisciplinary
effort to address the fascinating questions that arise from this consideration.
Within our current research culture scholars routinely ask, "To what extent
do genes influence __1" The __ can be filled in with dozens of
interesting and socially-important topics, including disease, intelligence,
personality, divorce, television viewing, and general health and happiness,
just to namea few. Onerelatively unexplored setofbehaviors, however, are
the theoretical starting point for human existence: Those related to
reproductive success. Surprisingly, little coherent attention has been given
to whether and how genes influence sexual behavior, fertility, and
reproduction. Likewise, there has been little coherent effort devoted to
studying the combination of influences in gene/environment interactions.
This volume is an effort to both provide and stimulate the development of
thatcoherence.
In December, 1997, at the Arizona Inn in Tucson, in a charming little
conference room furnished with a roaring fire and a heavily-decorated
Christmas tree, two dozen scholars from all over the world convened a
conference entitled "Genetic Influences on Fertility and Related Processes."
The conference was co-sponsored by the Office of Behavioral and Social
Science Research ofthe National Institutes ofHealth and by the Society for
the Study of Social Biology. This edited volume emerged from that
conference. Afollow-up conference on the same topic is scheduled to occur
in Rostock, Germany in summer, 2000, at the Max Planck Institute for
Demographic Research; this second conference is also sponsored by the
OBSSRbranchofNIH, alongwith the Max Planck Institute.
Many individuals contributed time, energy, and insight to the production
of this book. All of the papers were carefully peer-reviewed; the review
team included Kaare Christensen, Bruce Ellis, Warren Miller, David Pasta,
Joe Rodgers, and David Rowe. At the University of Oklahoma, Debby