Exploring Poisonous Plants Poisonous plants are used in traditional medicine systems in various healing therapies. They are a rich resource of ingredients used in herbal drug formulations that are also used in the development of synthetic drugs. They are recognized for their antioxidant, anti-inflammation, anti-cancer, and anti-diabetic activities and for many other health benefits. Exploring Poisonous Plants: Medicinal Values, Toxicity Responses, and Therapeutic Uses provides an analysis of the most important poisonous herbs, shrubs, and trees, detailing poisonous plants while demonstrating endorsements for their potential therapeutic values. Features: Presents therapeutic potentials on various poisonous herbs, shrubs, and trees. Provides descriptions of notable toxic compounds and discusses their adverse effects when consumed by animals or people. Gives practical guidance for botanical description, distribution, phytochemical constituents, phar- macological studies, and traditional and other potential uses of selected poisonous plants. This volume in the Exploring Medicinal Plants series is appropriate for scientists, researchers, and students working with poisonous plants, as well as in areas of economic botany, plant b iochemistry, biotechnology, pharmacognosy, pharmaceuticals, industrial chemistry, and nanomedicine. Exploring Medicinal Plants Series Editor: Azamal Husen Wolaita Sodo University, Ethiopia Medicinal plants render a rich source of bioactive compounds used in drug formulation and devel- opment; they play a key role in traditional or indigenous health systems. As the demand for herbal medicines increases worldwide, their supply is declining as most of the harvest is derived from naturally growing vegetation. Considering global interests and covering several important aspects associated with medicinal plants, the Exploring Medicinal Plants series comprises volumes valu- able to academia, practitioners, and researchers interested in medicinal plants. Topics provide infor- mation on a range of subjects including diversity, conservation, propagation, cultivation, physiology, molecular biology, growth response under extreme environment, handling, storage, bioactive com- pounds, secondary metabolites, extraction, therapeutics, mode of action, and healthcare practices. Led by Azamal Husen, PhD, this series is directed to a broad range of researchers and profes- sionals consisting of topical books exploring information related to medicinal plants. It includes edited volumes, references, and textbooks available for individual print and electronic purchases. Sustainable Uses of Medicinal Plants Learnmore Kambizi and Callistus Bvenura Omics Studies of Medicinal Plants Ahmad Altaf Traditional Herbal Therapy for the Human Immune System Azamal Husen Environmental Pollution and Medicinal Plants Azamal Husen Herbs, Shrubs, and Trees of Potential Medicinal Benefits Azamal Husen Phytopharmaceuticals and Biotechnology of Herbal Plants Sachidanand Singh, Rahul Datta, Parul Johri, and Mala Trivedi Exploring Poisonous Plants: Medicinal Values, Toxicity Responses, and Therapeutic Uses Azamal Husen Plants as Medicine and Aromatics: Conservation, Ecology, and Pharmacognosy Mohd Kafeel Ahmad Ansari, Bengu Turkyilmaz Unal, Munir Ozturk, and Gary Owens Medicinal Plant Responses to Stressful Conditions Arafat Abdel Hamed Abdel Latef Exploring Poisonous Plants Medicinal Values, Toxicity Responses, and T herapeutic Uses Edited by Azamal Husen Designed cover image: © Shutterstock First edition published 2023 by CRC Press 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742 and by CRC Press 4 Park Square, Milton Park, Abingdon, Oxon, OX14 4RN CRC Press is an imprint of Taylor & Francis Group, LLC © 2023 Taylor & Francis Group, LLC Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. 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For works that are not available on CCC please contact [email protected] Trademark notice: Product or corporate names may be trademarks or registered trademarks and are used only for identification and explanation without intent to infringe. Library of Congress Cataloging‑in‑Publication Data Names: Husen, Azamal, editor. Title: Exploring poisonous plants : medicinal values, toxicity responses, and therapeutic uses / edited by Azamal Husen. Description: First edition. | Boca Raton, FL: CRC Press, 2023. | Includes bibliographical references and index. Identifiers: LCCN 2022038657 (print) | LCCN 2022038658 (ebook) | ISBN 9781032311371 (hardback) | ISBN 9781032311388 (paperback) | ISBN 9781003308249 (ebook) Subjects: LCSH: Poisonous plants—Therapeutic use. | Medicinal plants. | Materia medica, Vegetable. Classification: LCC QK100.A1 E97 2023 (print) | LCC QK100.A1 (ebook) | DDC 581.6/59—dc23/eng/20220825 LC record available at https://lccn.loc.gov/2022038657 LC ebook record available at https://lccn.loc.gov/2022038658 ISBN: 9781032311371 (hbk) ISBN: 9781032311388 (pbk) ISBN: 9781003308249 (ebk) DOI: 10.1201/b23017 Typeset in Times by codeMantra To my sister, Kaiser Jahan Contents About the Editor ................................................................................................................................xi Preface............................................................................................................................................xiii Contributors .....................................................................................................................................xv Section A General information Chapter 1 Poisonous Plants: An Overview ...................................................................................3 Mustehasan, Gulwaiz Akhter, and Azamal Husen Chapter 2 Biotechnological Approaches in Poisonous Plants ....................................................31 Lubna Azmi Chapter 3 Uses of Poisonous Plants in Nanoscience ..................................................................41 Apekshakumari Patel, Nimisha Patel, Ahmad Ali, and Hina Alim Chapter 4 Conservation Practices of Poisonous Plants: Present Status ......................................67 Rakesh Kumar and Ram Kumar Section B P oisonous Plants (Botanical Description, Distribution, Phytochemical constituents, Pharmacological Studies, toxic Response, traditional, and other Potential Uses and Future Remarks) Chapter 5 Abrus precatorius (Rosary Pea) .................................................................................87 Mansi Shah, Meenakshi K, and Indu Anna George Chapter 6 Aconitum napellus (Monkshood) .............................................................................101 Karma Yeshi and Phurpa Wangchuk Chapter 7 Acorus calamus (Sway or Muskrat Root) ................................................................113 Yashashree Pradhan, Hina Alim, Nimisha Patel, Johra Khan, Belkıs Muca Yiğit, Kamal Fatima Zahra, and Ahmad Ali Chapter 8 Agapanthus orientalis (Lily of the Nile) ..................................................................125 Godwin Anywar vii viii Contents Chapter 9 Antiaris toxicaria (Upas Tree) .................................................................................129 Suraj Dhanyakumar Umdale, Pankaj Shivnarayan Mundada, and Mahendra Laxman Ahire Chapter 10 Aristolochia indica (The Indian Birthwort) .............................................................139 Surjit Sen, Sudeshna Nandi, Rupa Sanyal, Abhijit Dey, and Manjula Rai Chapter 11 Atractylis gummifera (Stemless Atractylis) .............................................................157 Noureddine Chaachouay and Lahcen Zidane Chapter 12 Atropa belladonna (Deadly Nightshade) .................................................................165 Arundhati Singh, Vedanshi Pal, Shreyshi Aggarwal, and Manu Pant Chapter 13 Calotropis gigantea (Crown Flower or Giant Milkweed)........................................179 Prabhjot Kaur, Amarjit Singh, and Jitender Sharma Chapter 14 Colchicum autumnale (Naked Ladies) ....................................................................195 Neha Sharma and Riddhima Singh Chapter 15 Conium maculatum (Hemlock or Poison Hemlock) ................................................203 Upagya Gyaneshwari, Akhilesh Kumar Singh, Priti Pal, and Brijesh Pandey Chapter 16 Datura stramonium (Thorn Apple or Devil’s Trumpet) ..........................................219 Tenzin Jamtsho, Ugyen, and Phurpa Wangchuk Chapter 17 Digitalis purpurea (Foxglove Plant) ........................................................................241 Tina, Vedanshi Pal, and Manu Pant Chapter 18 Gloriosa superba (Glory Lily) .................................................................................255 Umakanta Dash, Ankita Bhardwaj, Ashwath M. N., Preeti Vats, Sourav Ranjan Mohapatra, and Kajal Samantara Chapter 19 Nerium oleander (Oleander or Nerium) ...................................................................277 Kolagani Chandramohan and Salman Khan Chapter 20 Ricinus communis (Castor Oil Plant) .......................................................................289 Ambreen Bano, Adria Hasan, Swati Sharma, and Snober S. Mir Contents ix Chapter 21 Thevetia peruviana (Yellow Oleander) ....................................................................307 Subhrajit Banerjee, Senjuti Banerjee, Kasturi Sarkar, and Parames C. Sil Chapter 22 Toxicodendron succedaneum (Rhus or Wax Tree) ..................................................339 Godwin Anywar and Patience Tugume Index ..............................................................................................................................................345