European Journal of Pharmacology 1991: Vol 201 Index

11 Pages·1991·3.5 MB·English

European Journal of Pharmacology, 201 (1991) 253-255
© 1991 Elsevier Science Publishers B.V. All rights reserved 0014-/2919 /9$039.5 0
Author index
Abdi, S., see Loick, H.M. (201) 91 Engberg, G. and Wikstrom, H.
Adams, R.N., see Cammack, J. (201) 111 a-Receptors: implication for the control of neuronal activity of
Agen, C., see Blandizzi, C. (201) 35 nigral dopamine-containing neurons (201) 199
Allix, M., see Plotkine, M. (201) 115 Enna, S.J., see Noronha-Blob, L. (201) 135
Balazs, R., see Van der Valk, J.B.F. (201) 247 Fardin, V. and Garret, C.
Bang, L., see Nielsen-Kudsk, J.E. (201) 97 Species differences between [*H]substance P binding in rat and
Bengtsson, S., see Hall, H. (201) 1 guinea-pig shown by the use of peptide agonists and antagonists
Blandizzi, C., De Bona, M., Natale, G., Agen, C. and Del Tacca, M. (201) 231
Effects of quinolone carboxylic acid derivatives on GABA, re- Fernandez-Alfonso, M.S., see Marin, J. (201) 75
ceptor-mediated stimulation of gastric acid secretion and intesti- Ferreira, S.H., Duarte, 1.D.G. and Lorenzetti, B.B.
nal motility (201) 35 The molecular mechanism of action of peripheral morphine
Boddeke, H.W.G.M. analgesia: stimulation of the cGMP system via nitric oxide release
Different effects of muscarinic agonists in rat superior cervical (201) 121
ganglion and hippocampal slices (201) 191 Foulkes, R., Shaw, N., Bose, C. and Hughes, B.
Bose, C., see Foulkes, R. (201) 143 Differential vasodilator profile of calcitonin gene-related peptide
Boulu, R., see Plotkine, M. (201) 115 in porcine large and small diameter coronary artery rings (201)
Boura, A.L.A., see Rechtman, M.P. (201) 69 143
Bult, H., see Corten, I. (201) 83
Buyssens, N., see Corten, I. (201) 83 Garret, C., see Fardin, V. (201) 231
Gessa, G.L., see Rossetti, Z.L. (201) 243
Cammack, J., Tessel, R., Michaelis, E. and Adams, R.N. Goto, M., see Nakazawa, T. (201) 185
Antioxidants prevent the interaction of 3,4-dihydroxyphenylacetic Grande, P., see Stawski, G. (201) 123
acid at the dopamine D, receptor (201) 111 Guillou, J., see Plotkine, M. (201) 115
Caporali, M.G., see Popoli, P. (201) 11
Chang, K.-J., see Xu, S. (201) 215 Hall, H., Hogberg, T., Halldin, C., Bengtsson, S. and Wedel, I.
Chang, L.-R., see Tao, P.-L. (201) 209 Synthesis and binding properties of the fluorinated substituted
Chariot, J., see Nagain, C. (201) 203 benzamide [7H]NCQ 115, a new selective dopamine D, receptor
Chess-Williams, R., see Coker, S.J. (201) 103 ligand (201) 1
Cho, C.H., Liao, N.X., Liu, X.G., Hui, W.M., Luk, C.T. and Lam, Halldin, C., see Hall, H. (201) 1
S.K. Henry, J.L., see Hong, Y. (201) 171
Effects of adenosine on gastric and cardiovascular systems, and Herman, A.G., see Corten, I. (201) 83
ethanol ulceration in male and female rats (201) 157 Herndon, D.L., see Loick, H.M. (201) 91
Clark, D., see Overton, P. (201) 117 Hmaidan, Y., see Rossetti, Z.L. (201) 243
Code, R.A. and Tang, A.H. Hogberg, T., see Hall, H. (201) 1
Yawning produced by dopamine agonists in rhesus monkeys (201) Hong, Y. and Henry, J.L.
235 Phaclofen-reversible effects of GABA in the spinal cord of the
Coker, S.J. and Chess-Williams, R. rat (201) 171
Amiodarone, adrenoceptor responsiveness and ischaemia- and Hughes, B., see Foulkes, R. (201) 143
reperfusion-induced arrhythmias (201) 103 Hui, W.M., see Cho, C.H. (201) 157
Collins, M.A., see Xu, S. (201) 215
Cools, A.R., see Koshikawa, N. (201) 47 Jean, A., see Kessler, J.-P. (201) 59
Corten, I., Peeters, F.A.M., Rampart, M., Bult, H., Buyssens, N. and Johnson, D.N., see Young, R. (201) 151
Herman, A.G.
Ridogrel prevents the thromboxane-mediated pressor response Kameyama, T., see Toyoshi, T. (201) 41
and oedema induced by hydrogen peroxide in isolated rabbit Kaneko, T., see Nakazawa, T. (201) 185
lungs (201) 83 Katz, J.L., see Menkel, M. (201) 251
Kessler, J.-P. and Jean, A.
D’ Aquila, P.S., see Rossetti, Z.L. (201) 243 Evidence that activation of N-methyl-D-aspartate (NMDA) and
De Beltran, K.K., see Koshikawa, N. (201) 47 non-NMDA receptors within the nucleus tractus solitarii triggers
De Bona, M., see Blandizzi, C. (201) 35 swallowing (201) 59
De Carolis, A.S., see Popoli, P. (201) 11 King, R.G., see Rechtman, M.P. (201) 69
De Jong, W., see Linthorst, A.C.E. (201) 125 Kobayashi, M., see Koshikawa, N. (201) 47
De Lang, H., see Linthorst, A.C.E. (201) 125 Koshikawa, N., De Beltran, K.K., Tomiyama, K., Kobayashi, M. and
Del Tacca, M., see Blandizzi, C. (201) 35 Cools, A.R.
Duarte, I.D.G., see Ferreira, S.H. (201) 121 Functional interaction between dopamine D, and D, receptors
Dirmiiller, N., see Smith, S.E. (201) 179 in rat jaw movements (201) 47
254
Lam, S.K., see Cho, C.H. (201) 157 Hypothermia augments non-cholinergic neuronal bronchocon-
Laubie, M., see Verbeuren, T.J. (201) 17 striction in pithed guinea-pigs (201) 69
Lee, M., see Strahlendorf, J.C. (201) 239 Resink, A., see Van der Valk, J.B.F. (201) 247
Liao, N.X., see Cho, C.H. (201) 157 Rossetti, Z.L., D’Aquila, P.S., Hmaidan, Y., Gessa, G.L. and Serra,
Linthorst, A.C.E., De Lang, H., De Jong, W. and Versteeg, D.H.G. G.
Effect of the dopamine D, receptor agonist quinpirole on the in Repeated treatment with imipramine potentiates cocaine-in-
vivo release of dopamine in the caudate nucleus of hypertensive duced dopamine release and motor stimulation (201) 243
rats (201) 125 Rozé, C., see Nagain, C. (201) 203
Liu, X.G., see Cho, C.H. (201) 157
Loh, H.H., see Tao, P.-L. (201) 209 Sanchez-Ferrer, C.F., see Marin, J. (201) 75
Loick, H.M., Tokyay, R., Abdi, S., Traber, D.L., Nichols, R.J. and Serra, G., see Rossetti, Z.L. (201) 243
Herndon, D.L. Shaw, N., see Foulkes, R. (201) 143
Halothane markedly reduces mesenteric blood flow but does not Smith, S.E., Durmuller, N. and Meldrum, B.S.
impair gut mucosal oxygenation in pigs (201) 91 The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466
Lorenzetti, B.B., see Ferreira, S.H. (201) 121 and NBQX are anticonvulsant in two animal models of reflex
Lowe, V.C., see Noronha-Blob, L. (201) 135 epilepsy (201) 179
Luk, C.T., see Cho, C.H. (201) 157
Sprouse, J.S.
Inhibition of dorsal raphe cell firing by MDL 73005EF, a novel
Marin, J., Fernandez-Alfonso, M.S. and Sanchez-Ferrer, C.F. 5-HT,, receptor ligand (201) 163
Sodium punip activity and contractile effect of ouabain in human
Stawski, G., Olsen, U.B. and Grande, P.
placental veins (201) 75 Cytotoxic effect of endothelin-1 during ‘simulated’ ischaemia in
Marshall, I.G., see Wannan, G. (201) 29 cultured rat myocytes (201) 123
Meldrum, B.S., see Smith, S.E. (201) 179 Strahlendorf, H.K., see Strahlendorf, J.C. (201) 239
Menkel, M., Terry, P., Pontecorvo, M., Katz, J.L. and Witkin, J.M. Strahlendorf, J.C., Lee, M. and Strahlendorf, H.K.
Selective o ligands block stimulant effects of cocaine (201) 251 Serotonin modulates muscimol- and baclofen-elicited inhibition
Mennecier, P., see Verbeuren, T.J. (201) 17 of cerebellar Purkinje cells (201) 239
Michaelis, E., see Cammack, J. (201) 111 Sturm, B.L., see Noronha-Blob, L. (201) 135
Nagain, C., Chariot, J., Vaille, C. and Rozé, C.
Tachibana, S., see Nakazawa, T. (201) 185
Effect of modafinil on pancreatic exocrine secretion in the rat. A
Taki, T., see Nakazawa, T. (201) 185
comparison with methadone (201) 203
Tang, A.H., see Code, R.A. (201) 235
Nakazawa, T., Kaneko, T., Yoshino, H., Tachibana, S., Goto, M.,
Tao, P.-L., Tsai, C.-L., Chang, L.-R. and Loh, H.H.
Taki, T. and Yamatsu, K.
Chronic effect of [D-Pen?,D-Pen* enkephalin on rat brain opioid
Physical dependence liability of dynorphin A analogs in rodents
receptors (201) 209
(201) 185
Terry, P., see Menkel, M. (201) 251
Natale, G., see Blandizzi, C. (201) 35
Tessel, R., see Cammack, J. (201) 111
Nichols, R.J., see Loick, H.M. (201) 91
Toda, N., see Yamazaki, M. (201) 223
Nielsen-Kudsk, J.E. and Bang, L.
Tokyay, R., see Loick, H.M. (201) 91
Effects of pinacidil and other cyanoguanidine derivatives on
Tomiyama, K., see Koshikawa, N. (201) 47
guinea-pig isolated trachea, aorta and pulmonary artery (201) 97
Toyoshi, T., Ukai, M. and Kameyama, T.
Noronha-Blob, L., Prosser, J.C., Sturm, B.L., Lowe, V.C. and Enna,
[D-Ala*,NMePhe‘*,Gly-ol°Jenkephalin, but not [D-Pen?,L-
S.J.
Pen Jenkephalin, specifically inhibits behaviors induced by the
(+)-Terodiline: an M,-selective muscarinic receptor antagonist.
dopamine D, agonist RU 24213 (201) 41
In vivo effects at muscarinic receptors mediating urinary bladder
Traber, D.L., see Loick, H.M. (201) 91
contraction, mydriasis and salivary secretion (201) 135
Trautmann, M., Peskar, B.M. and Peskar, B.A.
Aspirin-like drugs, ethanol-induced rat gastric injury and mucosal
Olsen, U.B., see Stawski, G. (201) 123
eicosanoid release (201) 53
Overton, P. and Clark, D.
Tsai, C.-L., see Tao, P.-L. (201) 209
N-Methyl-D-aspartate increases the excitability of nigrostriatal
dopamine terminals (201) 117
Ukai, M., see Toyoshi, T. (201) 41
Peeters, F.A.M., see Corten, I. (201) 83
Peskar, B.A., see Trautmann, M. (201) 53 Vaille, C., see Nagain, C. (201) 203
Peskar, B.M., see Trautmann, M. (201) 53 Van der Valk, J.B.F., Resink, A. and Balazs, R.
Plotkine, M., Allix, M., Guillou, J. and Boulu, R. Membrane depolarization and the expression of glutamate recep-
Oral administration of isosorbide dinitrate inhibits arterial tors in cerebellar granule cells (201) 247
thrombosis in rats (201) 115 Verbeuren, T.J., Mennecier, P. and Laubie, M.
Pontecorvo, M., see Menkel, M. (201) 251 5-Hydroxytryptamine-induced vasodilatation in the isolated per-
Popoli, P., Caporali, M.G. and De Carolis, A.S. fused rat kidney: are endothelial 5-HT,, receptors involved?
Interactions between dopamine D, and D, receptors in the (201) 17
model of thyrotropin-releasing hormone (TRH)-induced be- Versteeg, D.H.G., see Linthorst, A.C.E. (201) 125
haviour in rabbits (201) 11
Prior, C., see Wannan, G. (201) 29 Wannan, G., Prior, C. and Marshall, I.G.
Prosser, J.C., see Noronha-Blob, L. (201) 135 a-Adrenoceptor blocking properties of vesamicol (201) 29
Wedel, I., see Hall, H. (201) 1
Rampart, M., see Corten, I. (201) 83 Wikstrom, H., see Engberg, G. (201) 199
Rechtman, M.P., King, R.G. and Boura, A.L.A. Witkin, J.M., see Menkel, M. (201) 251
255
Xu, S., Collins, M.A. and Chang, K.-J. Comparison of responses to angiotensin II of dog mesenteric
Phorbol esters induce oscillatory contractions of intestinal smooth arteries and veins (201) 223
muscles (201) 215 Yoshino, H., see Nakazawa, T. (201) 185
Young, R. and Johnson, D.N.
Yamatsu, K., see Nakazawa, T. (201) 185 Anxiolytic-like activity of R(+)- and S(—)-zacopride in mice
Yamazaki, M. and Toda, N. (201) 151

European Journal of Pharmacology, 201 (1991) 257-262
© 1991 Elsevier Science Publishers B.V. All rights reserved 0014-/2919 /9$039.5 0
Key word index
Adenosine Arrhythmias
Ethanol; Gastric mucosal blood flow; Gastric secretion; Gastric Amiodarone; Coronary artery occlusion; Reperfusion; Adrenoceptor
damage; Cardiovascular system; (Rat) (Cho, C.H. (201) 157) responsiveness (Coker, S.J. (201) 103)
Adrenoceptor responsiveness Arterial pressure
Amiodarone; Coronary artery occlusion; Reperfusion; Arrhythmias GABA (y-aminobutyric acid); Bicuculline; Phaclofen; Heart rate;
(Coker, S.J. (201) 103) Spinal cord; (Intrathecal) (Hong, Y. (201) 171)
Adrenoceptors Arterial thrombosis
Pancreatic exocrine secretion; Modafinil; Methadone; Opiate recep- Isosorbide dinitrate; Nitrovasodilators; Antithrombotics; (Rat)
tors (Nagain, C. (201) 203) (Plotkine, M. (201) 115)
a -Adrenoceptors Ascorbic acid
Vesamicol; AH5183; Vas deferens (rat); Uptake, (Wannan, G. (201) DOPAC (3,4-dihydroxyphenylacetic acid); Dopamine D, receptors;
29) Auto-oxidation (Cammack, J. (201) 111)
Auto-oxidation
AHS5183
DOPAC (3,4-dihydroxyphenylacetic acid); Ascorbic acid; Dopamine
Vesamicol; Vas deferens (rat); a-Adrenoceptors; Uptake, (Wannan,
D, receptors (Cammack, J. (201) 111)
G. (201) 29)
Baclofen
Amiodarone
5-HT (5-hydroxytryptamine, serotonin); Muscimol; Cerebellum;
Coronary artery occlusion; Reperfusion; Arrhythmias; Adrenoceptor
Purkinje cells (Strahlendorf, J.C. (201) 239)
responsiveness (Coker, S.J. (201) 103)
Behaviour
Angiotensin II
Dopamine D, receptors; Dopamine D, receptors; Thyrotropin-re-
Prostaglandin I,; Mesenteric artery; Mesenteric vein; EDRF (endo-
leasing hormone (TRH); (Rabbit) (Popoli, P. (201) 11)
thelium-derived relaxing factor) (Yamazaki, M. (201) 223)
Benzamides (fluorinated, substituted)
Antidepressants
Dopamine D, receptors; Receptor binding (in vitro) (Hall, H. (201)
Microdialysis; Cocaine; Reward (Rossetti, Z.L. (201) 243)
1)
Antiinflammatory drugs (non-steroidal)
Bicuculline
Gastric injury (rat); Leukotriene C,; 6-keto-Prostaglandin F,,; 15-
GABA (y-aminobutyric acid); Phaclofen; Arterial pressure; Heart
Hydroxy-5,8,11,13-eicosatetraenoic acid; Gastroprotection (Traut-
rate; Spinal cord; (Intrathecal) (Hong, Y. (201) 171)
mann, M. (201) 53)
Bladder instability
Antithrombotics Terodiline; Pirenzepine; Propantheline; Urinary incontinence; Mus-
Isosorbide dinitrate; Nitrovasodilators; Arterial thrombosis; (Rat)
carinic receptor subtypes; Cystometrogram; Mydriasis; Salivation
(Plotkine, M. (201) 115)
(Noronha-Blob, L. (201) 135)
Anxiolytic activity
Bradykinin
5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal
Protein kinase C; Ca” *-channel inhibitors; Nifedipine; Ca* *-mobiliz-
raphe nucleus; Receptor reserve; 8-OH-DPAT (8-hydroxy-2-(di-n-
ing ligands; Muscarinic receptor agonists; Histamine (Xu, S. (201)
propylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201)
215)
163)
Brain (guinea-pig)
Anxiolytic-like activity Brain (rat); Ileum (guinea-pig); Substance P; Tachykinin receptors
Light /dark test; Zacopride isomers (Young, R. (201) 151) (Fardin, V. (201) 231)
Aorta Brain (rat)
Pinacidil; Cyanoguanidines; K* channels; Trachea; Pulmonary artery Ileum (guinea-pig); Brain (guinea-pig); Substance P; Tachykinin re-
(Nielsen-Kudsk, J.E. (201) 97) ceptors (Fardin, V. (201) 231)
Apomorphine Bronchoconstriction
o-Receptors; Substantia nigra; Dopamine neurons; (+ )-3-PPP ((+)- Non-cholinergic response; Substance P; Temperature; (Guinea-pig)
3-(3-hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201) 199) (Rechtman, M.P. (201) 69)
258
Buspirone DOPAC (3,4-dihydroxyphenylacetic acid)
5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal Ascorbic acid; Dopamine D, receptors; Auto-oxidation (Cammack,
raphe nucleus; Receptor reserve; Anxiolytic activity; 8-OH-DPAT J. (201) 111)
(8-hydroxy-2-(di-n-propylamino)tetralin); (Autoreceptor) (Sprouse,
J.S. (201) 163) Dopamine
Glutamate; NMDA (N-methyl-D-aspartate); Terminal excitability;
Ca?*-channel inhibitors Neostriatum; (Rat) (Overton, P. (201) 117)
Protein kinase C: Nifedipine; Ca?*-mobilizing ligands; Muscarinic
receptor agonists; Histamine; Bradykinin (Xu, S. (201) 215) Quinpirole; Caudate nucleus; Spontaneously hypertensive rat (SHR);
Hypertension; Microdialysis (Linthorst, A.C.E. (201) 125)
Ca?*-mobilizing ligands
Protein kinase C; Ca**-channel inhibitors; Nifedipine; Muscarinic Dopamine neurons
receptor agonists; Histamine; Bradykinin (Xu, S. (201) 215) o-Receptors; Substantia nigra; Apomorphine; (+ )-3-PPP ((+ )-3-(3-
hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201) 199)
5-Carboxamidotryptamine
Renal vasodilatation; Endothelium dilatation; 5-HT,, receptors; 8- Dopamine D, /D, receptor interaction
OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); Tertatolol Oral movements; Electromyographic activity; SK&F 38393; Quinpi-
(Verbeuren, T.J. (201) 17) role; (Rat) (Koshikawa, N. (201) 47)
Dopamine D, receptors
Cardiovascular system
Dopamine D, receptors; Thyrotropin-releasing hormone (TRH);
Adenosine; Ethanol; Gastric mucosal blood flow; Gastric secretion;
Gastric damage; (Rat) (Cho, C.H. (201) 157) Behaviour; (Rabbit) (Popoli, P. (201) 11)
Dopamine D, receptors
Caudate nucleus
Benzamides (fluorinated, substituted); Receptor binding (in vitro)
Dopamine; Quinpirole; Spontaneously hypertensive rat (SHR); Hy-
(Hall, H. (201) 1)
pertension; Microdialysis (Linthorst, A.C.E. (201) 125)
Dopamine D, receptors; Thyrotropin-releasing hormone (TRH); Be-
Cerebellum
haviour; (Rabbit) (Popoli, P. (201) 11)
5-HT (5-hydroxytryptamine, serotonin); Muscimol; Baclofen; Pur-
kinje cells (Strahlendorf, J.C. (201) 239)
DOPAC (3,4-dihydroxyphenylacetic acid); Ascorbic acid; Auto-
oxidation (Cammack, J. (201) 111)
Granule cells; Glutamate; Excitatory amino acid receptors; Trophic
factors; Voltage clamp (Van der Valk, J.B.F. (201) 247)
Dopaminergic compounds
Yawning; (Rhesus monkey) (Code, R.A. (201) 235)
CGRP-(8-37)
CGRP (calcitonin gene-related peptide); Coronary artery (porcine);
Dorsal raphe nucleus
Vasodilators (Foulkes, R. (201) 143)
5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Receptor
reserve; Anxiolytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n-pro-
CGRP (calcitonin gene-related peptide)
pylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201)
CGRP-(8-37); Coronary artery (porcine); Vasodilators (Foulkes, R.
163)
(201) 143)
DPDPE ([D-Pen?,D-Pen*]enkephalin)
Cocaine Tolerance; Opioid receptors; (Rat) (Tao, P.-L. (201) 209)
Antidepressants; Microdialysis; Reward (Rossetti, Z.L. (201) 243)
DPLPE ([D-Pen’,L-Pen*]enkephalin)
Coronary artery occlusion DAGO ({D-Ala?,NMePhe‘*,Gly-ol°]enkephalin); RU 24213; B-
Amiodarone; Reperfusion; Arrhythmias; Adrenoceptor responsive- Funaltrexamine; Locomotor activity; (Mouse) (Toyoshi, T. (201) 41)
ness (Coker, S.J. (201) 103)
Dynorphin A analogs
Coronary artery (porcine) E-2078; Physical dependence (Nakazawa, T. (201) 185)
CGRP (calcitonin gene-related peptide); CGRP-(8-37); Vasodilators
(Foulkes, R. (201) 143) E-2078
Dynorphin A analogs; Physical dependence (Nakazawa, T. (201) 185)
Cyanoguanidines
Pinacidil; K* channels; Trachea; Pulmonary artery; Aorta (Nielsen- EDRF (endothelium-derived relaxing factor)
Kudsk, J.E. (201) 97) Angiotensin II; Prostaglandin I,; Mesenteric artery; Mesenteric vein
(Yamazaki, M. (201) 223)
Cystometrogram
Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary Electromyographic activity
incontinence; Muscarinic receptor subtypes; Mydriasis; Salivation Oral movements; SK&F 38393; Quinpirole; Dopamine D, /D, re-
(Noronha-Blob, L. (201) 135) ceptor interaction; (Rat) (Koshikawa, N. (201) 47)
DAGO ([D-Ala?,NMePhe‘*,Gly-ol>]enkephalin) Endothelial distress
DPLPE ([D-Pen’,L-Pen> Jenkephalin); RU 24213; B-Funaltrexamine; H,O,; Ridogrel; Thromboxane; 5-HT uptake; Lung (rabbit) (Corten,
Locomotor activity; (Mouse) (Toyoshi, T. (201) 41) I. (201) 83)
Endothelium dilatation Gastroprotection
Renal vasodilatation; 5-HT,, receptors; 8-OH-DPAT (8-hydroxy-2- Gastric injury (rat); Leukotriene C,; 6-keto-Prostaglandin F,,; 15-
(di-n-propylamino)tetralin); 5-Carboxamidotryptamine; Tertatolol Hydroxy-5,8,11,13-eicosatetraenoic acid; Antiinflammatory drugs
(Verbeuren, T.J. (201) 17) (non-steroidal) (Trautmann, M. (201) 53)
Epilepsy Glutamate
Quisqualate; NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)- Dopamine; NMDA (N-methyl-D-aspartate); Terminal excitability;
quinoxaline); Non-NMDA receptor antagonists; GYKI 52466; Exci- Neostriatum; (Rat) (Overton, P. (201) 117)
tatory amino acids (Smith, S.E. (201) 179)
Cerebellum; Granule cells; Excitatory amino acid receptors; Trophic
Ethanol factors; Voltage clamp (Van der Valk, J.B.F. (201) 247)
Adenosine; Gastric mucosal blood flow; Gastric secretion; Gastric
damage; Cardiovascular system; (Rat) (Cho, C.H. (201) 157) Granule cells
Cerebellum; Glutamate; Excitatory amino acid receptors; Trophic
Excitatory amino acid receptors factors; Voltage clamp (Van der Valk, J.B.F. (201) 247)
Cerebellum; Granule cells; Glutamate; Trophic factors; Voltage
clamp (Van der Valk, J.B.F. (201) 247) GYKI 52466
Quisqualate; NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-
Excitatory amino acids quinoxaline); Non-NMDA receptor antagonists; Excitatory amino
Quisqualate; NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)- acids; Epilepsy (Smith, S.E. (201) 179)
quinoxaline); Non-NMDA receptor antagonists; GYKI 52466;
Epilepsy (Smith, S.E. (201) 179) Halothane
Mesenteric blood flow; Mucosal perfusion; (Pig) (Loick, H.M. (201)
B-Funaltrexamine 91)
DAGO ((D-Ala?,NMePhe?4,Gly-ol°Jenkephalin); DPLPE ((D-
Pen’,L-Pen° Jenkephalin); RU 24213; Locomotor activity; (Mouse) Heart rate
(Toyoshi, T. (201) 41) GABA (y-aminobutyric acid); Bicuculline; Phaclofen; Arterial pres-
sure; Spinal cord; (Intrathecal) (Hong, Y. (201) 171)
GABA (y-aminobutyric acid)
Bicuculline; Phaclofen; Arterial pressure; Heart rate; Spinal cord; Hippocampal slice (rat)
(Intrathecal) (Hong, Y. (201) 171) Superior cervical ganglion (rat); Muscarinic M, receptors (Boddeke,
H.W.G.M. (201) 191)
GABA, receptor agonists
Quinolone carboxylic acid; GABA, receptors; GABA, receptor Histamine
antagonists; Gastric acid secretion; Intestinal motility (Blandizzi, C. Protein kinase C; Ca?*-channel inhibitors; Nifedipine; Ca? *-mobiliz-
(201) 35) ing ligands; Muscarinic receptor agonists; Bradykinin (Xu, S. (201)
215)
GABA, receptor antagonists
Quinolone carboxylic acid; GABA, receptors; GABA, receptor H,0,
agonists; Gastric acid secretion; Intestinal motility (Blandizzi, C. Ridogrel; Thromboxane; 5-HT uptake; Endothelial distress; Lung
(201) 35) (rabbit) (Corten, I. (201) 83)
GABA , receptors 5-HT (5-hydroxytryptamine, serotonin)
Quinolone carboxylic acid; GABA, receptor agonists; GABA, re- 5-HT,, receptors; Dorsal raphe nucleus; Receptor reserve; Anxi-
ceptor antagonists; Gastric acid secretion; Intestinal motility (Blan- olytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin);
dizzi, C. (201) 35) Buspirone; (Autoreceptor) (Sprouse, J.S. (201) 163)
Gastric acid secretion Muscimol; Baclofen; Cerebellum; Purkinje cells (Strahlendorf, J.C.
Quinolone carboxylic acid; GABA, receptors; GABA, receptor (201) 239)
agonists; GABA , receptor antagonists; Intestinal motility (Blandizzi,
C. (201) 35) 5-HT,, receptors
Renal vasodilatation; Endothelium dilatation; 8-OH-DPAT (8-hy-
Gastric damage droxy-2-(di-n-propylamino)tetralin); 5-Carboxamidotryptamine; Ter-
Adenosine; Ethanol; Gastric mucosal blood flow; Gastric secretion; tatolol (Verbeuren, T.J. (201) 17)
Cardiovascular system; (Rat) (Cho, C.H. (201) 157)
5-HT (5-hydroxytryptamine, serotonin); Dorsal raphe nucleus; Re-
Gastric injury (rat) ceptor reserve; Anxiolytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n-
Leukotriene C,; 6-keto-Prostaglandin F,,; 15-Hydroxy-5,8,11,13- propylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201)
eicosatetraenoic acid; Antiinflammatory drugs (non-steroidal); Gas- 163)
troprotection (Trautmann, M. (201) 53)
5-HT uptake
Gastric mucosal blood flow H,0,; Ridogrel; Thromboxane; Endothelial distress; Lung (rabbit)
Adenosine; Ethanol; Gastric secretion; Gastric damage; Cardiovas- (Corten, I. (201) 83)
cular system; (Rat) (Cho, C.H. (201) 157)
15-Hydroxy-5,8,11,13-eicosatetraenoic acid
Gastric injury (rat); Leukotriene C,; 6-keto-Prostaglandin F,,,; Anti-
Gastric secretion
Adenosine; Ethanol; Gastric mucosal blood flow; Gastric damage; inflammatory drugs (non-steroidal); Gastroprotection (Trautmann,
Cardiovascular system; (Rat) (Cho, C.H. (201) 157) M. (201) 53)
260
Hypertension Mucosal perfusion
Dopamine; Quinpirole; Caudate nucleus; Spontaneously hyperten- Halothane; Mesenteric blood flow; (Pig) (Loick, H.M. (201) 91)
sive rat (SHR); Microdialysis (Linthorst, A.C.E. (201) 125)
Muscarinic receptor agonists
Ileum (guinea-pig) Protein kinase C; Ca?*-channel inhibitors; Nifedipine; Ca? *-mobiliz-
Brain (rat); Brain (guinea-pig); Substance P; Tachykinin receptors ing ligands; Histamine; Bradykinin (Xu, S. (201) 215)
(Fardin, V. (201) 231)
Muscarinic M, receptors
Intestinal motility Superior cervical ganglion (rat); Hippocampal slice (rat) (Boddeke,
Quinolone carboxylic acid; GABA, receptors; GABA, receptor H.W.G.M. (201) 191)
agonists; GABA, receptor antagonists; Gastric acid secretion
(Blandizzi, C. (201) 35) Muscarinic receptor subtypes
Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary
Isosorbide dinitrate incontinence; Cystometrogram; Mydriasis; Salivation (Noronha-Blob,
Nitrovasodilators; Arterial thrombosis; Antithrombotics; (Rat) L. (201) 135)
(Plotkine, M. (201) 115)
Muscimol
K* channels 5-HT (5-hydroxytryptamine, serotonin); Baclofen; Cerebellum; Pur-
Pinacidil; Cyanoguanidines; Trachea; Pulmonary artery; Aorta (Niel- kinje cells (Strahlendorf, J.C. (201) 239)
sen-Kudsk, J.E. (201) 97)
Mydriasis
Leukotriene C, Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary
Gastric injury (rat); 6-keto-Prostaglandin F,,,; 15-Hydroxy-5,8,11,13- incontinence; Muscarinic receptor subtypes; Cystometrogram; Saliva-
eicosatetraenoic acid; Antiinflammatory drugs (non-steroidal); Gas- tion (Noronha-Blob, L. (201) 135)
troprotection (Trautmann, M. (201) 53)
NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F)-quinoxaline)
Light /dark test Quisqualate; Non-NMDA receptor antagonists; GYKI 52466; Excita-
Zacopride isomers; Anxiolytic-like activity (Young, R. (201) 151) tory amino acids; Epilepsy (Smith, S.E. (201) 179)
Locomotor activity Neostriatum
DAGO ({(D-Ala?,NMePhe?,Gly-ol°]Jenkephalin); DPLPE ({D- Dopamine; Glutamate; NMDA (N-methyl-D-aspartate); Terminal
Pen’,L-Pen* Jenkephalin); RU 24213; B-Funaltrexamine; (Mouse) excitability; (Rat) (Overton, P. (201) 117)
(Toyoshi, T. (201) 41)
Nifedipine
Lung (rabbit) Protein kinase C; Ca**-channel inhibitors; Ca?*-mobilizing ligands;
H,O,; Ridogrel; Thromboxane; 5-HT uptake; Endothelial distress Muscarinic receptor agonists; Histamine; Bradykinin (Xu, S. (201)
(Corten, I. (201) 83) 215)
Mesenteric artery Nitrovasodilators
Angiotensin II; Prostaglandin I,; Mesenteric vein; EDRF (endo- Isosorbide dinitrate; Arterial thrombosis; Antithrombotics; (Rat)
thelium-derived relaxing factor) (Yamazaki, M. (201) 223) (Plotkine, M. (201) 115)
Mesenteric blood flow NMDA (N-methyl-D-aspartate)
Halothane; Mucosal perfusion; (Pig) (Loick, H.M. (201) 91) Dopamine; Glutamate; Terminal excitability; Neostriatum; (Rat)
(Overton, P. (201) 117)
Mesenteric vein
Angiotensin II; Prostaglandin I,; Mesenteric artery; EDRF (endo- NMDA receptors
thelium-derived relaxing factor) (Yamazaki, M. (201) 223) Swallowing; Non-NMDA receptors; Motor pattern; Nucleus tractus
solitarii; (Decerebrate rat) (Kessler, J.-P. (201) 59)
Methadone
Pancreatic exocrine secretion; Adrenoceptors; Modafinil; Opiate re- Non-cholinergic response
ceptors (Nagain, C. (201) 203) Bronchoconstriction; Substance P; Temperature; (Guinea-pig)
(Rechtman, M.P. (201) 69)
Microdialysis
Dopamine; Quinpirole; Caudate nucleus; Spontaneously hyperten- Non-NMDA receptor antagonists
sive rat (SHR); Hypertension (Linthorst, A.C.E. (201) 125) Quisqualate; NBOX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-
quinoxaline); GYKI 52466; Excitatory amino acids; Epilepsy (Smith,
Antidepressants; Cocaine; Reward (Rossetti, Z.L. (201) 243) S.E. (201) 179)
Modafinil Non-NMDA receptors
Pancreatic exocrine secretion; Adrenoceptors; Methadone; Opiate Swallowing; NMDA receptors; Motor pattern; Nucleus tractus soli-
receptors (Nagain, C. (201) 203) tarii; (Decerebrate iat) (Kessler, J.-P. (201) 59)
Motor pattern Nucleus tractus solitarii
Swallowing; NMDA receptors; Non-NMDA receptors; Nucleus trac- Swallowing; NMDA receptors; Non-NMDA receptors; Motor pat-
tus solitarii; (Decerebrate rat) (Kessler, J.-P. (201) 59) tern; (Decerebrate rat) (Kessler, J.-P. (201) 59)
8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin) Pulmonary artery
Renal vasodilatation; Endothelium dilatation; 5-HT,, receptors; 5- Pinacidil; Cyanoguanidines; K* channels; Trachea; Aorta (Nielsen-
Carboxamidotryptamine; Tertatolol (Verbeuren, T.J. (201) 17) Kudsk, J.E. (201) 97)
5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal Purkinje cells
raphe nucleus; Receptor reserve; Anxiolytic activity; Buspirone; (Au- 5-HT (5-hydroxytryptamine, serotonin); Muscimol; Baclofen; Cere-
toreceptor) (Sprouse, J.S. (201) 163) bellum (Strahlendorf, J.C. (201) 239)
Opiate receptors
Quinolone carboxylic acid
Pancreatic exocrine secretion; Adrenoceptors; Modafinil; Methadone
GABA, receptors; GABA, receptor agonists; GABA, receptor
(Nagain, C. (201) 203)
antagonists; Gastric acid secretion; Intestinal motility (Blandizzi, C.
(201) 35)
Opioid receptors
Tolerance; DPDPE ({D-Pen’,D-Pen? Jenkephalin); (Rat) (Tao, P.-L.
Quinpirole
(201) 209)
Oral movements; Electromyographic activity; SK&F 38393;
Dopamine D, /D, receptor interaction; (Rat) (Koshikawa, N. (201)
Oral movements
47)
Electromyographic activity; SK&F 38393; Quinpirole; Dopamine
D, /D, receptor interaction; (Rat) (Koshikawa, N. (201) 47)
Dopamine; Caudate nucleus; Spontaneously hypertensive rat (SHR);
Hypertension; Microdialysis (Linthorst, A.C.E. (201) 125)
Ouabain
Placental vein (human); [*H]Ouabain binding; °°Rb* uptake (Marin,
Quisqualate
J. (201) 75)
NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)-quinoxaline);
Non-NMDA receptor antagonists; GYKI 52466; Excitatory amino
[>H]Ouabain binding
Placental vein (human); °°Rb* uptake; Ouabain (Marin, J. (201) 75) acids; Epilepsy (Smith, S.E. (201) 179)
8s6Rb* uptake
Pancreatic exocrine secretion
Adrenoceptors; Modafinil; Methadone; Opiate receptors (Nagain, C. Placental vein (human); [*H]Ouabain binding; Ouabain (Marin, J.
(201) 203) (201) 75)
Phaclofen Receptor binding (in vitro)
GABA (y-aminobutyric acid); Bicuculline; Arterial pressure; Heart Benzamides (fluorinated, substituted); Dopamine D, receptors (Hall,
rate; Spinal cord; (Intrathecal) (Hong, Y. (201) 171) H. (201) 1)
Physical dependence Receptor reserve
Dynorphin A analogs; E-2078 (Nakazawa, T. (201) 185) 5-HT (5-hydroxytryptamine, serotonin); 5-HT,, receptors; Dorsal
raphe nucleus; Anxiolytic activity; 8-OH-DPAT (8-hydroxy-2-(di-n-
Pinacidil propylamino)tetralin); Buspirone; (Autoreceptor) (Sprouse, J.S. (201)
Cyanoguanidines; K* channels; Trachea; Pulmonary artery; Aorta 163)
(Nielsen-Kudsk, J.E. (201) 97)
o -Receptors
Pirenzepine Substantia nigra; Dopamine neurons; Apomorphine; (+) -3-PPP
Terodiline; Propantheline; Bladder instability; Urinary incontinence;
((+ )-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201)
Muscarinic receptor subtypes; Cystometrogram; Mydriasis; Salivation
199)
(Noronha-Blob, L. (201) 135)
Renal vasodilatation
Placental vein (human)
Endothelium dilatation; 5-HT,, receptors; 8-OH-DPAT (8-hydroxy-
[?H]Ouabain binding; °°Rb* uptake; Ouabain (Marin, J. (201) 75)
2-(di-n-propylamino)tetralin); 5-Carboxamidotryptamine; Tertatolol
(Verbeuren, T.J. (201) 17)
Propantheline
Terodiline; Pirenzepine; Bladder instability; Urinary incontinence;
Reperfusion
Muscarinic receptor subtypes; Cystometrogram; Mydriasis; Salivation
Amiodarone; Coronary artery occlusion; Arrhythmias; Adrenoceptor
(Noronha-Blob, L. (201) 135)
responsiveness (Coker, S.J. (201) 103)
6-keto-Prostaglandin F,,,
Reward
Gastric injury (rat); Leukotriene C,; 15-Hydroxy-5,8,11,13-eico-
Antidepressants; Microdialysis; Cocaine (Rossetti, Z.L. (201) 243)
satetraenoic acid; Antiinflammatory drugs (non-steroidal); Gastro-
protection (Trautmann, M. (201) 53)
Ridogrel
Prostaglandin I, H,O,; Thromboxane; 5-HT uptake; Endothelial distress; Lung (rab-
bit) (Corten, I. (201) 83)
Angiotensin II; Mesenteric artery; Mesenteric vein; EDRF (endo-
thelium-derived relaxing factor) (Yamazaki, M. (201) 223)
RU 24213
DAGO ({D-Ala*,NMePhe‘,Gly-ol° Jenkephalin); DPLPE ((D-
Protein kinase C
Ca**-channel inhibitors; Nifedipine; Ca**-mobilizing ligands; Mus- Pen?,L-Pen? Jenkephalin); B-Funaltrexamine; Locomotor activity;
carinic receptor agonists; Histamine; Bradykinin (Xu, S. (201) 215) (Mouse) (Toyoshi, T. (201) 41)
262
Salivation OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin); 5-Carboxami-
Terodiline; Pirenzepine; Propantheline; Bladder instability; Urinary dotryptamine (Verbeuren, T.J. (201) 17)
incontinence; Muscarinic receptor subtypes; Cystometrogram; Mydri-
asis (Noronha-Blob, L. (201) 135) Thromboxane
H,0O,; Ridogrel; '5-HT uptake; Endothelial distress; Lung (rabbit)
SK&F 38393 (Corten, I. (201) 83)
Oral movements; Electromyographic activity; Quinpirole; Dopamine
D, /D, receptor interaction; (Rat) (Koshikawa, N. (201) 47) Thyrotropin-releasing hormone (TRH)
Dopamine D, receptors; Dopamine D, receptors; Behaviour; (Rab-
Spinal cord bit) (Popoli, P. (201) 11)
GABA (y-aminobutyric acid); Bicuculline; Phaclofen; Arterial pres-
sure; Heart rate; (Intrathecal) (Hong, Y. (201) 171) Tolerance
DPDPE ([D-Pen?,D-Pen° Jenkephalin); Opioid receptors; (Rat) (Tao,
Spontaneously hypertensive rat (SHR) P.-L. (201) 209)
Dopamine; Quinpirole; Caudate nucleus; Hypertension; Microdialy-
sis (Linthorst, A.C.E. (201) 125) Trachea
Pinacidil; Cyanoguanidines; K* channels; Pulmonary artery; Aorta
Substance P (Nielsen-Kudsk, J.E. (201) 97)
Non-cholinergic response; Bronchoconstriction; Temperature;
(Guinea-pig) (Rechtman, M.P. (201) 69)
Trophic factors
Cerebellum; Granule cells; Glutamate; Excitatory amino acid recep-
Brain (rat); Ileum (guinea-pig); Brain (guinea-pig); Tachykinin recep-
tors; Voltage clamp (Van der Valk, J.B.F. (201) 247)
tors (Fardin, V. (201) 231)
Uptake,
Substantia nigra
Vesamicol; AH5183; Vas deferens (rat); a-Adrenoceptors (Wannan,
o-Receptors; Dopamine neurons; Apomorphine; (+ )-3-PPP ((+ )-3-
G. (201) 29)
(3-hydroxyphenyl)-N-(1-propyl)piperidine) (Engberg, G. (201) 199)
Urinary incontinence
Superior cervical ganglion (rat)
Terodiline; Pirenzepine; Propantheline; Bladder instability; Mus-
Hippocampal slice (rat); Muscarinic M, receptors (Boddeke,
carinic receptor subtypes; Cystometrogram; Mydriasis; Salivation
H.W.G.M. (201) 191)
(Noronha-Blob, L. (201) 135)
Swallowing
Vas deferens (rat)
NMDA receptors; Non-NMDA receptors; Motor pattern; Nucleus
Vesamicol; AH5183; a-Adrenoceptors; Uptake, (Wannan, G. (201)
tractus solitarii; (Decerebrate rat) (Kessler, J.-P. (201) 59)
29)
Tachykinin receptors
Vasodilators
Brain (rat); Ileum (guinea-pig); Brain (guinea-pig); Substance P
CGRP (calcitonin gene-related peptide); CGRP-(8-37); Coronary
(Fardin, V. (201) 231)
artery (porcine) (Foulkes, R. (201) 143)
Temperature
Non-cholinergic response; Bronchoconstriction; Substance P; Vesamicol
AHS5183; Vas deferens (rat); a-Adrenoceptors; Uptake, (Wannan, G.
(Guinea-pig) (Rechtman, M.P. (201) 69)
(201) 29)
Terminal excitability
Dopamine; Glutamate; NMDA (N-methyl-D-aspartate); Neostria- Voltage clamp
tum; (Rat) (Overton, P. (201) 117) Cerebellum; Granule cells; Glutamate; Excitatory amino acid recep-
tors; Trophic factors (Van der Valk, J.B.F. (201) 247)
Terodiline
Pirenzepine; Propantheline; Bladder instability; Urinary inconti- Yawning
nence; Muscarinic receptor subtypes; Cystometrogram; Mydriasis; Dopaminergic compounds; (Rhesus monkey) (Code, R.A. (201) 235)
Salivation (Noronha-Blob, L. (201) 135)
Zacopride isomers
Tertatolol Light /dark test; Anxiolytic-like activity (Young, R. (201) 151)
Renal vasodilatation; Endothelium dilatation; 5-HT,, receptors; 8-