Detection of apex motion for monitoring cardiac dysfunction

26 Pages·2013·2.18 MB·English

US007445605B2
(12) United States Patent (10) Patent No.: US 7,445,605 B2
Overall et al. (45) Date of Patent: Nov. 4, 2008
(54) DETECTION OF APEX MOTION FOR (52) US. Cl. ..................... .. 600/595; 600/483; 600/527;
MONITORING CARDIAC DYSFUNCTION 600/587; 607/17; 607/ 19
(58) Field of Classi?cation Search ............... .. 600/ 595,
(75) Inventors: William Ryan Overall, Palo Alto, CA 600/587, 508, 481, 483, 527; 607/9, 17*19
(US); Daniel Francis, Los Altos, CA See application ?le for complete search history.
(US); Aimee Brigitte Angel, Atherton, .
CA (US); R. HardWin Mead, P2110 Alto, (56) References C‘ted
CA (Us) US. PATENT DOCUMENTS
(73) Assignee: The Board of Trustees of the Leland i glafnmang
ginkgo‘ Jum.o r Unlv. erslt. y’ Palo Alto’ 5,, 693,, 075 A 12/1997 P1100 0a1n11 et a1.
(U ) 5,899,927 A 5/l999 Ecker et a1.
( * ) Notice: Subject' to any disclaimer, the term of this i (A3400; 3137M
patent 1s extended or adjusted under 35 6,501,983 B1 12/2002 Natamjan et 31‘
USC 15401) by 0 days- 6,595,933 B2* 7/2003 Sarvazyan et a1. ........ .. 600/587
2003/0158492 A1 * 8/2003 Sheldon et a1. ........... .. 600/508
(21) Appl.No.: 11/394,449
FOREIGN PATENT DOCUMENTS
WO WO0306l473 7/2003
(65) Prior Publication Data
* cited by examiner
US 2007/0032749 A1 Feb. 8, 2007
Primary ExamineriMax Hindenburg
Related US. Application Data Assistant ExamineriH. Q. Nguyen
(63) Continuation-in-part of application No. 10/769 405 (74) Attorney’ Agent’ or FirmiBOZiCeVic’ Field & Francis
?led on Jan. 30, 2004, noW abandoned. LLP; Pamela 1' Sherwood
(60) Provisional application No. 60/473,061, ?led on May (57) ABSTRACT
23, 2003, provisional application No. 60/443,938, _ _ _ _
?led on Jan 31’ 2003_ Systems, dev1ces and methods for detectlng and momtorlng
cardiac dysfunction. The devices include motion sensors for
(51) Int_ CL detecting signals representative of the total movement of the
A613 5/103 (200601) heart, and of the apex of the heart in particular.
A61B 5/02 (2006.01)
A61N 1/00 (2006.01) 14 Claims, 12 Drawing Sheets
US. Patent Nov. 4, 2008 Sheet 1 0f 12 US 7,445,605 B2
US. Patent Nov. 4, 2008 Sheet 2 0f 12 US 7,445,605 B2
102
US. Patent Nov. 4, 2008 Sheet 3 0f 12 US 7,445,605 B2
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Fig. 3
US. Patent Nov. 4, 2008 Sheet 4 0f 12 US 7,445,605 B2
Fig. 4(a) Fig. 4(b)
Fig. 4(0) Fig. 4(d)
US. Patent Nov. 4, 2008 Sheet 5 0f 12 US 7,445,605 B2
US. Patent Nov. 4, 2008 Sheet 6 0f 12 US 7,445,605 B2
602
605
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Fig. 6(0)
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Fig. 6(d)
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Fig. 7(a) Fig. 7(b)
US. Patent Nov. 4, 2008 Sheet 7 0f 12 US 7,445,605 B2
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Fig. 7(d)
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Fig. 8(a) Fig. 8(b)
US. Patent Nov. 4, 2008 Sheet 8 0f 12 US 7,445,605 B2
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Fig. 8(c) Fig. 8(d)
US. Patent Nov. 4, 2008 Sheet 9 0f 12 US 7,445,605 B2
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