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Clinical Hematology Atlas PDF

278 Pages·2016·23.161 MB·English
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CONTENTS Section 1 Introduction 1 Introduction toPeripheral Blood FilmExamination 1 Section 2 Hematopoiesis 2 Hematopoiesis 11 3 Erythrocyte Maturation 17 4 MegakaryocyteMaturation 31 5 Neutrophil Maturation 41 6 MonocyteMaturation 55 7 Eosinophil Maturation 65 8 Basophil Maturation 75 9 Lymphocyte Maturation 79 Section 3 Erythrocytes 10 Variationsin Size and Color ofErythrocytes 89 11 Variationsin Shapeand Distribution of Erythrocytes 93 12 Inclusionsin Erythrocytes 107 13 DiseasesAffecting Erythrocytes 115 Section 4 Leukocytes 14 Nuclearand Cytoplasmic Changes inLeukocytes 131 15 Acute Myeloid Leukemia 139 16 PrecursorLymphoid Neoplasms 157 17 Myeloproliferative Neoplasms 161 18 MyelodysplasticSyndromes 171 19 Mature LymphoproliferativeDisorders 181 20 Morphologic Changes after Myeloid HematopoieticGrowth Factors 191 Section 5 Miscellaneous 21 Microorganisms 195 22 MiscellaneousCells 203 23 NormalNewborn Peripheral BloodMorphology 215 24 Body Fluids 219 Glossary 241 Appendix: Comparison Tables 261 Index 265 Clinical Hematology Atlas YOU’VE JUST PURCHASED MORE THAN A TEXTBOOK! Evolve Student Resources for Rodak: Clinical Hematology Atlas, 5th edition include the following: (cid:129) AdditionalPhotosforIdentification (cid:129) StudentReviewQuestions (cid:129) SummaryTables Activate the completelearning experiencethatcomes with each textbook purchaseby registeringat http://evolve.elsevier.com/Rodak/ REGISTER TODAY! You can now purchase Elsevier products on Evolve! Go to evolve.elsevier.com/html/shop-promo.html to search and browse for products. Fifth Edition Clinical Hematology Atlas Bernadette F. Rodak, MS, MT(ASCP)SH Professor Emeritus Clinical Laboratory Science Program Department of Pathology and Laboratory Medicine Indiana University School of Medicine Indianapolis, Indiana Jacqueline H. Carr, MS, MT(ASCP)SH Former Laboratory Manager Department of Pathology and Laboratory Medicine Indiana University Health Indianapolis, Indiana 3251RiverportLane St.Louis,Missouri63043 CLINICALHEMATOLOGYATLAS,FIFTHEDITION ISBN:978-0-323-32249-2 Copyright©2017byElsevier,Inc.Allrightsreserved. Nopartofthispublicationmaybereproducedortransmittedinanyformorbyanymeans,electronicor mechanical,includingphotocopying,recording,oranyinformationstorageandretrievalsystem,without permissioninwritingfromthepublisher.Detailsonhowtoseekpermission,furtherinformationaboutthe Publisher’spermissionspoliciesandourarrangementswithorganizationssuchastheCopyrightClearance CenterandtheCopyrightLicensingAgency,canbefoundatourwebsite:www.elsevier.com/permissions. ThisbookandtheindividualcontributionscontainedinitareprotectedundercopyrightbythePublisher (otherthanasmaybenotedherein). Notices Knowledgeandbestpracticeinthisfieldareconstantlychanging.Asnewresearchandexperiencebroaden ourunderstanding,changesinresearchmethods,professionalpractices,ormedicaltreatmentmaybecome necessary. Practitionersandresearchersmustalwaysrelyontheirownexperienceandknowledgeinevaluatingand usinganyinformation,methods,compounds,orexperimentsdescribedherein.Inusingsuchinformation ormethodstheyshouldbemindfuloftheirownsafetyandthesafetyofothers,includingpartiesforwhom theyhaveaprofessionalresponsibility. Withrespecttoanydrugorpharmaceuticalproductsidentified,readersareadvisedtocheckthemost currentinformationprovided(i)onproceduresfeaturedor(ii)bythemanufacturerofeachproducttobe administered,toverifytherecommendeddoseorformula,themethodanddurationofadministration,and contraindications.Itistheresponsibilityofpractitioners,relyingontheirownexperienceandknowledgeof theirpatients,tomakediagnoses,todeterminedosagesandthebesttreatmentforeachindividualpatient, andtotakeallappropriatesafetyprecautions. Tothefullestextentofthelaw,neitherthePublishernortheauthors,contributors,oreditors,assumeanyliability foranyinjuryand/ordamagetopersonsorpropertyasamatterofproductsliability,negligenceorotherwise,or fromanyuseoroperationofanymethods,products,instructions,orideascontainedinthematerialherein. Previouseditionscopyrighted2013,2009,2004,and1999. InternationalStandardBookNumber:978-0-323-32249-2 LibraryofCongressCataloging-in-PublicationData Rodak,BernadetteF.,author. Clinicalhematologyatlas/BernadetteF.Rodak,JacquelineH.Carr. –Fifthedition. p.;cm. Includesindex. ISBN978-0-323-32249-2(pbk.:alk.paper) I.Carr,JacquelineH.,author.II.Title. [DNLM:1.HematologicDiseases–diagnosis–Atlases.2.HematologicDiseases–pathology–Atlases.WH17] RB145 616.1'5–dc23 2015036694 ExecutiveContentStrategist:KellieWhite ContentDevelopmentManager:LaurieGower ContentDevelopmentSpecialist:KarenTurner PublishingServicesManager:JulieEddy ProjectManager:AbigailBradberry DesignDirection:JuliaDummitt PrintedinChina Lastdigitistheprintnumber:9 8 7 6 5 4 3 2 1 To ourhusbands, RobertHartman and Charles Carr, daughters, KimberlyCarrMayrose and AlexisCarr, and allof our colleagues who have encouragedus tocontinue topublish this atlas inits concise format This page intentionally left blank REVIEWERS Steven Marionneux, MS,MT(ASCP) Manager,Clinical Hematology Laboratories Memorial Sloan KetteringCancer Center New York, New York Adjuct Assistance Professor, Clinical Laboratory Sciences Rutgers,The State University of New Jersey Newark,New Jersey Alisa J. Petree, MHSM,MLS(ASCP)cm Professor/Clinical Coordinator McLennanCommunity College Waco, Texas vii This page intentionally left blank

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