Biochemical Pharmacology 2003: Vol 66 Table of Contents

16 Pages·2003·5.4 MB·English

ELSEVIER Biochemical Pharmacology 66 (2003) 2449-2464
www.elsevier.com/locate/biochempharm
Contents of Volume 66
1 July 2003 83 =T he antioxidant ESeroS-GS inhibits NO production
and prevents oxidative stress in astrocytes
Taotao Wei, Xingyu Zhao, Jingwu Hou, Kazumi Ogata,
Commentary
Takahiro Sakaue, Akitane Mori and Wenjuan Xin
1 Iron interactions and other biological reactions med-
iating the physiological and toxic actions of manganese 93 Molecular mechanism of gossypol-induced cell
growth inhibition and cell death of HT-29 human
Jerome A. Roth and Michael D. Garrick
colon carcinoma cells
Manchao Zhang, Hongpeng Liu, Ribo Guo, Yan Ling,
MOLECULAR AND CELLULAR PHARMACOLOGY
Xiaojin Wu, Bihua Li, Peter P. Roller, Shaomeng Wang
15 Role of the AP-1 element and redox factor-1 (Ref-1) and Dajun Yang
in mediating transcriptional induction of DT-
105 Cocaine—protein targets in mouse liver
diaphorase gene expression by oltipraz: a target for
Florence M. Ndikum-Moffor and Stephen M. Roberts
chemoprevention
Kang-Shen Yao and Peter J. O’ Dwyer
CHEMOTHERAPY AND METABOLIC INHIBITORS
25 Involvement of nuclear transcription factor-KB in
115 Investigation of anticancer mechanism of thiadiazole-
low-dose doxorubicin-induced drug resistance of cer-
based compound in human non-small cell lung can-
vical carcinoma cells
cer A549 cells
Pei Yen Yeh, Shuang-En Chuang, Kun-Huei Yeh,
Jui-Yi Chou, Shin-Yu Lai, Shiow-Lin Pan,
Ying Chyi Song and Ann-Lii Cheng
Guey-Mei Jow, Ji-Wang Chern and JiheHwa Guh
35 Tryptophan metabolism via serotonin in rats with
NEUROSCIENCE
hexachlorobenzene experimental porphyria
Elena B.C. Llambias, Carmen Aldonatti and 125 5,7-Dihydroxy-6-methoxyflavone, a benzodiazepine
Leonor C. San Martin de Viale site ligand isolated from Scutellaria baicalensis Georgi,
43 Nitric oxide has a role in regulating VLA-4-integrin with selective antagonistic properties
expression on the human neutrophil cell surface Michael S.Y. Huen, Justin W.C. Leung, Wah Ng,
W.S. Lui, Michelle N.S. Chan, J. Tze-Fei Wong and
Nicola Conran, Alessandra Gambero,
Hong Xue
Heloisa H.A. Ferreira, Edson Antunes and
Gilberto de Nucci
HORMONES AND GROWTH FACTORS
a1 Positive and negative regulation of prostaglandin E,
133 The role of c-Myc on granulocyte colony-stimulating
biosynthesis in human colorectal carcinoma cells by
factor-dependent neutrophilic proliferation and dif-
cancer chemopreventive agents
ferentiation of HL-60 cells
Philip J. Sherratt, Lesley I. McLellan and John D. Hayes
Toshie Kanayasu-Toyoda, Teruhide Yamaguchi,
63 Cytotoxic and xenoestrogenic effects via biotransfor-
Tadashi Oshizawa, Eriko Uchida and Takao Hayakawa
mation of trans-anethole on isolated rat hepatocytes
141, Stimulation of catecholamine synthesis by orexin-A
and cultured MCF-7 human breast cancer cells
in bovine adrenal medullary cells through orexin
Yoshio Nakagawa and Toshinari Suzuki
receptor |
15 Tubulin polymerizing activity of dictyostatin-1, a
Yasusada Kawada, Susumu Ueno, Kohtaro Asayama,
polyketide of marine sponge origin Masato Tsutsui, Kensuke Utsunomiya,
Richard A. Isbrucker, Jennifer Cummins, Yumiko Toyohira, Naoya Morisada, Kazumi Tanaka,
Shirley A. Pomponi, Ross E. Longley and Amy E. Wright Akira Shirahata and Nobuyuki Yanagihara
doi: 10.1016/S0006-2952(03)00837-2
Contents of Volume 66
INFLAMMATION AND IMMUNOPHARMACOLOGY 213 Role of tissue transglutaminase in GTP depletion-
induced apoptosis of insulin-secreting (HIT-T15)
Potentiation of tumor necrosis factor-% expression by
cells
YC-1 in alveolar macrophages through a cyclic GMP-
JianXin Huo, Stewart A. Metz and GuoDong Li
independent pathway
Tsong-Long Hwang, Chin-Chung Wu, DNA strand breaks and apoptosis induced by oxali-
Jih-Hwa Guh and Che-Ming Teng platin in cancer cells
Sandrine Faivre, Denise Chan, Richard Salinas,
Barbara Woynarowska and Jan M. Woynarowski
CARDIOVASCULAR AND PULMONARY PHARMACOLOGY
Specific expression of an A-kinase anchoring protein
Spermine-induced negative inotropic effect in iso-
subtype, AKAP-150, and specific regulatory mechan-
lated rat heart, is mediated through the release of
ism for Na’,K*-ATPase via protein kinase A in the
ATP
parotid gland among the three major salivary glands
Gustavo Guevara-Balcdzar,
of the rat
Enrique Querejeta-Villagomez,
Kinji Kurihara, Nobuo Nakanishi, Osamu Amano,
Oskar Nuevo-Adalla,
Miyuki Yamamoto and Shoichi Iseki
Alejandra Orozco-Guillen,
Ivan Rubio-Gayosso, Jose R. Herndndez-Castillo, Structural determinants for the activation mechan-
Miguel Zamora-Garza and Guillermo Ceballos-Reyes ism of the angiotensin II type 1 receptor differ for
phosphoinositide hydrolysis and mitogen-activated
protein kinase pathways
GASTROINTESTINAL AND RENAL PHARMACOLOGY
John Hines, Steven J. Fluharty and Daniel K. Yee
Decreased expression of P-glycoprotein during differ-
entiation in the human intestinal cell line Caco-2 YC-1 inhibits proliferation of human vascular
endothelial cells through a cyclic GMP-independent
Maki Goto, Satohiro Masuda, Hideyuki Saito and
pathway
Ken-ichi Inui
Hun-Kung Hsu, Shu-Hui Juan, Pei-Yin Ho,
Effect of spironolactone on the expression of rat hepa- Yu-Chih Liang, Chien-Huang Lin, Che-Ming Teng and
tic UDP-glucuronosyltransferase
Wen-Sen Lee
Viviana A. Catania, Marcelo G. Luquita,
Immunosuppressant PG490 (triptolide) induces
Enrique J. Sdnchez Pozzi, Shin-ichi Ikushiro,
apoptosis through the activation of caspase-3 and
Yoshikazu Emi, Takashi Iyanagi and Aldo D. Mottino
down-regulation of XIAP in U937 cells
Yun-Jung Choi, Tae Gyu Kim, Young-Ho Kim,
Sung-Hee Lee, Young Kyu Kwon, Seong-Il Suh,
15 July 2003
Jong-Wook Park and Taeg Kyu Kwon
Commentary (CHEMOTHERAPY AND METABOLIC INHIBITORS
Search for a common mechanism of mood stabilizers
The mitochondrial uncoupler dicumarol disrupts the
Adrian J. Harwood and Galila Agam MTT assay
Abby C. Collier and Chris A. Pritsos
MOLECULAR AND CELLULAR PHARMACOLOGY
NEUROSCIENCE
Inhibition of cholinesterases with cationic phosphonyl
oximes highlights distinctive properties of the Diclofenac inhibits proliferation and differentiation
charged pyridine groups of quaternary oxime reacti- of neural stem cells
vators
Chiho Kudo, Maya Kori, Kiyomi Matsuzaki,
Yacov Ashani, Apurba K. Bhattacharjee, Haim Leader, Kenshiki Yamai, Atsushi Nakajima,
Ashima Saxena and Bhupendra P. Doctor Atsuhito Shibuya, Hitoshi Niwa,
Yoshinori Kamisaki and Koichiro Wada
Role of protein kinase C in BSA-AGE-mediated
inducible nitric oxide synthase expression in RAW Acetyl-L-carnitine cytoprotection against 1-methyl-
264.7 macrophages 4-phenylpyridinium toxicity in neuroblastoma cells
Chih-Hsiung Wu, Chien-Hsi Chang, Hsiu-Chen Lin, Elizabeth Mazzio, Kyoung J. Yoon and
Chien-Ming Chen, Chien-Huang Lin and Horng-Mo Lee Karam F.A. Soliman
Contents of Volume 66 2451
HORMONES AND GROWTH FACTORS 379 Inhibition of Na’,K*-ATPase by the extract of
Stephania cephararantha HAyATA and bisbenzylisoqui-
Effects of troglitazone on intracellular cholesterol dis-
noline alkaloid cycleanine, a major constituent
tribution and cholesterol-dependent cell functions in
Kanako Satoh, Fumiko Nagai, Minoru Ono and
MA-10 Leydig tumor cells
Naoto Aoki
Dale A. Freeman and Angela Romero
Two possible orientations of the HI-6 molecule in the
reactivation of organophosphate-inhibited acetyl-
STRUCTURAL BIOLOGY
cholinesterase
Mutagenesis studies of the human MT, melatonin
Chunyuan Luo, Haim Leader, Zoran Radic,
receptor
Donald M. Maxwell, Palmer Taylor,
Matthew J. Gerdin, Faika Mseeh and
Bhupendra P. Doctor and Ashima Saxena
Margarita L. Dubocovich
Treatment with lovastatin, cholestyramine or
niacin alters K-ras membrane association in mouse
INFLAMMATION AND IMMUNOPHARMACOLOGY
lung in a_strain-dependent manner: results in
Expression and characterization of the chemokine females
receptor CCR2B from rhesus monkey
Richard J. Calvert, Shirley Tepper,
Hong Jin, Pasquale P. Vicario, Hans Zweerink, Bhalchandra A. Diwan, Lucy M. Anderson and
Shefali Goyal, William A. Hanlon, Conrad P. Dorn, David Kritchevsky
Sander G. Mills, Julie A. DeMartino,
Margaret A. Cascieri and Mary Struthers Interaction of polyhalogenated compounds of appro-
priate configuration with mammalian or bacterial
Histamine releasing peptide (HRP) has proinflamma-
CYP enzymes. Increased bilirubin and uroporphyrino-
tory effects and is present at sites of inflammation
gen oxidation in vitro
David E. Cochrane, Robert E. Carraway,
Nicoletta Pons, Sandra Pipino and
Lisa A. Miller, Ross S. Feldberg and Harry Bernheim
Francesco De Matteis
Chicken DT40 cells stably transfected with the rat
GASTROINTESTINAL AND RENAL PHARMACOLOGY
P2X7 receptor ion channel: a system suitable for the
B.-Adrenoceptor activation inhibits Shiga toxin2-
study of purine receptor-mediated cell death
induced apoptosis of renal tubular epithelial cells
Kate A. Hillman, Hitoshi Harada, Choong M. Chan,
Akio Nakamura, Akira Imaizumi,
Andrea Townsend-Nicholson, Stephen E. Moss,
Yukishige Yanagawa, Ryo Niimi, Takao Kohsaka
Kengo Miyamoto, Yasunobu Suketa,
and Edward J. Johns
Geoffrey Burnstock, Robert J. Unwin and
Preventive effect of silymarin against taurolitho- Philip M. Dunn
cholate-induced cholestasis in the rat
Inhibition of ATP-sensitive K* channels by substi-
Fernando A. Crocenzi, Enrique J. Sanchez Pozzi,
tuted benzo[c]quinolizinium CFTR activators
José M. Pellegrino, Emilio A. Rodriguez Garay,
Anne-Lise Prost, Renaud Dérand, Laurent Gros,
Aldo D. Mottino and Marcelo G. Roma
Frédéric Becq and Michel Vivaudou
Induction of resistance to the multitargeted antifolate
1 August 2003
Pemetrexed (ALIMTA) in WiDr human colon can-
cer cells is associated with thymidylate synthase over-
expression
Commentary
Jennifer Sigmond, Harold H.J. Backus, Dorine Wouters,
Anaplerotic reactions in tumour proliferation and
Olaf H. Temmink, Gerrit Jansen and
apoptosis
Godefridus J. Peters
Gerard Quash, Guy Fournet and Uwe Reichert
Effects of FK506 and rapamycin on generation of
reactive oxygen species, nitric oxide production
MOLECULAR AND CELLULAR PHARMACOLOGY
and nuclear factor kappa B activation in rat
Involvement of PKA and Sp1 in the induction of hepatocytes
p27‘?! by tamoxifen Maria Jesvis Tunon, Sonia Sadnchez-Campos,
Te-Hsiu Lee, Hui-Chiu Chang, Lea-Yea Chuang and Belén Gutiérrez, Jestis M. Culebras and
Wen-Chun Hung Javier Gonzalez-Gallego
Contents of Volume 66
(CHEMOTHERAPY AND METABOLIC INHIBITORS CARDIOVASCULAR AND PULMONARY PHARMACOLOGY
The anti-neoplastic and novel topoisomerase [I- DNA damage and expression of checkpoint genes
mediated cytotoxicity of neoamphimedine, a marine p2pr ORO! sad! 1be34 3 in taurine-deficient
pyridoacridine cardiomyocytes
Kathryn M. Marshall, Sandra S$. Matsumoto, Olga Golubnitschaja, Heike Moenkemann,
Joseph A. Holden, Gisela P. Concepcion, Kerstin Kim and Mahmood S. Moxaffari
Deniz Tasdemir, Chris M. Ireland and
Proteinase-activated receptor-2 mediates hyper-
Louis R. Barrows
responsiveness in isolated guinea pig bronchi
The JNK, ERK and p53 pathways play distinct roles Victor E. Barrios, Mark A. Jarosinski and
in apoptosis mediated by the antitumor agents vin- Clifford D. Wright
blastine, doxorubicin, and etoposide
Cheryl Brantley-Finley, Christopher S. Lyle,
15 August 2003
Lihua Du, Mary E. Goodwin, Toria Hall,
Dominika Szwedo, G.P. Kaushal and
Timothy C. Chambers
Commentary
Cytosolic and mitochondrial deoxyribonucleotidases:
On the significance of the role of cellular stress
activity with substrate analogs, inhibitors and impli-
response reactions in the toxic actions of dioxin
cations for therapy
Fumio Matsumura
Cristina Mazzon, Chiara Rampazzo,
Maria Chiara Scaini, Lisa Gallinaro,
Anna Karlsson, Chris Meier, Jan Balzarini, MOLECULAR AND CELLULAR PHARMACOLOGY
Peter Reichard and Vera Bianchi
Analysis of cell cycle regulation by 1-mono-O-acyl-3-
Inhibition of DNA topoisomerases I and II, and O-(a-b-sulfoquinovosyl)-glyceride (SQMG), an inhi-
growth inhibition of human cancer cell lines by a bitor of eukaryotic DNA polymerases
marine microalgal polysaccharide Chikako Murakami, Masaharu Takemura,
Ken Umemura, Kae Yanase, Mitsue Suzuki, Hiromi Yoshida, Fumio Sugawara,
Koichi Okutani, Takao Yamori and Toshiwo Andoh Kengo Sakaguchi and Yoshiyuki Mizushina
Characterization of sequence-dependent synergy
between ZD1839 (‘Iressa’) and oxaliplatin
NEUROSCIENCE
Jian-Ming Xu, Amalia Azzariti, Montemuro Severino,
Iron-binding characteristics of neuromelanin of the
Bing Lu, Giuseppe Colucci and Angelo Paradiso
human substantia nigra
Hepatobiliary elimination of bile acid-modified oligo-
Kay L. Double, Manfred Gerlach, Volker Schtinemann,
deoxynucleotides in Wistar and TR’ rats: evidence
Alfred X. Trautwein, Luigi Zecca, Mario Gallorini,
for mrp2 as carrier for oligodeoxynucleotides
Moussa B.H. Youdim, Peter Riederer and
Dorit Ben-Shachar Kerstin Lischka, Dieter Starke, Klaus Failing,
Andreas Herling, Werner Kramer and Ernst Petzinger
Influence of tumor necrosis factor-% on the expres-
HORMONES AND GROWTH FACTORS
sion and function of P-glycoprotein in an immorta-
Inhibition of MG-63 cell cycle progression by lised rat brain capillary endothelial cell line, GPNT
synthetic vitamin D3; analogs mediated by p27,
David Théron, Sylvie Barraud de Lagerie,
Cdk2, cyclin E, and the retinoblastoma protein
Sylviane Tardivel, Héléne Peélerin, Philippe Demeuse,
Sanna Ryhdnen, Tiina Jddskelainen, Anitta Mahonen Claire Mercier, Aloise Mabondzo, Robert Farinotti,
and Pekka H. Madenpdaa
Bernard Lacour, Francoise Roux and Francois Gimenez
A role for increased mRNA stability in the induction
INFLAMMATION AND IMMUNOPHARMACOLOGY of endothelin-1 synthesis by lipopolysaccharide
Julie A. Douthwaite, Delphine M. Lees and Roger Corder
IL-18BPa:Fe cooperates with immunosuppressive
drugs in human whole blood Different mechanisms for y-glutamyltransferase-
Marcel Nold, Ingeborg A. Hauser, Sonja Héfler, dependent resistance to carboplatin and cisplatin
Andreas Goede, Wolfgang Eberhardt, Till Ditting, Sandrine Daubeuf, Diane Balin, Pierre Leroy and
Helmut Geiger, Josef Pfeilschifter and Heiko Muihl Athanase Visvikis
Contents of Volume 66
The study of the quercetin action on human erythro-
1 September 2003
cyte membranes
Bozena Pawlikowska-Pawlega, Wieslaw I. Gruszecki,
Lucjan E. Misiak and Antoni Gawron
Commentary
Vertebrate UDP-glucuronosyltransferases: functional
Identification of gene expression profiles predicting
and evolutionary aspects
tumor cell response to L-alanosine
Karl Walter Bock
Thomas Efferth, Erich Gebhart, Douglas D. Ross and
Axel Sauerbrey
MOLECULAR AND CELLULAR PHARMACOLOGY
A dual mechanism of action of the anticancer agent
F 11782 on human topoisomerase II « Interferon gamma enhances proteasome activity in
recombinant Hep G2 cells that express cytochrome
Lars H. Jensen, Axelle Renodon-Corniere,
P4502E1: modulation by ethanol
Karin C. Nitiss, Bridget T. Hill, John L. Nitiss,
Peter B. Jensen and Maxwell Sehested Natalia A. Osna, Dahn L. Clemens and
Terrence M. Donohue Jr.
Regulation of pancreatic stellate cell function in vitro:
Synergistic effects of chemotherapeutic drugs in lym-
biological and molecular effects of all-trans retinoic
phoma cells are associated with down-regulation of
acid
inhibitor of apoptosis proteins (IAPs), prostate-apop-
Robert Jaster, Inken Hilgendorf, Brit Fitzner, tosis-response-gene 4 (Par-4), death-associated pro-
Peter Brock, Gisela Sparmann, Jorg Emmrich and tein (Daxx) and with enforced caspase activation
Stefan Liebe
Kai Uwe Chow, Daniel Nowak, Simone Boehrer,
Martin Ruthardt, Andrea Knau, Dieter Hoelzer,
Inhibition of prostaglandin D, clearance in rat hepa-
Paris S. Mitrou and Eckhart Weidmann
tocytes by the thromboxane receptor antagonists dal-
Induction of apoptosis in human hepatoblastoma
troban and ifetroban and the thromboxane synthase
cells by tetrandrine via caspase-dependent Bid clea-
inhibitor furegrelate
vage and cytochrome c release
Sabine Pestel, Annegret Nath, Kurt Jungermann and
Seon-Hee Oh and Byung-Hoon Lee
Henrike L. Schieferdecker
The novel nucleoside transport system exhibited by
NB4 cells, csg, transports deoxyguanosine analogues,
NEUROSCIENCE including ara-G
Degradation of endomorphin-2 at the supraspinal Sheryl A. Flanagan, Varsha Gandhi, John A. Secrist III
and Kelly A. Meckling
level in mice is initiated by dipeptidyl peptidase IV:
an in vitro and in vivo study Pyrazolotriazolopyrimidine derivatives sensitize mel-
Chikai Sakurada, Shinobu Sakurada, anoma cells to the chemotherapic drugs: taxol and
Takafumi Hayashi, Sou Katsuyama, vindesine
Koichi Tan-No and Tsukasa Sakurada Stefania Merighi, Prisco Mirandola, Katia Varani,
Stefania Gessi, Silvano Capitani, Edward Leung,
Pier Giovanni Baraldi, Mojgan Aghazadeh Tabrizi and
HORMONES AND GROWTH FACTORS Pier Andrea Borea
Antidiabetic and antimalarial biguanide drugs are The relationship between liver peroxisome prolifera-
metal-interactive antiproteolytic agents tion and adipose tissue atrophy induced by peroxi-
some proliferator exposure and withdrawal in mice
Deacon Sweeney, Michael L. Raymer and
Thomas D. Lockwood Yi Xie, Qian Yang, B. Dean Nelson and
Joseph W. DePierre
Inhibition of C6 glioma cell proliferation by anand-
INFLAMMATION AND IMMUNOPHARMACOLOGY
amide, l-arachidonoylglycerol, and by a water soluble
Down-regulation of c-jun N-terminal kinase-activa- phosphate ester of anandamide: variability in
tor protein-1 signaling pathway by Ginkgo biloba response and involvement of arachidonic acid
extract in human peripheral blood T cells
Christopher J. Fowler, Kent-Olov Jonsson,
Shu-Meng Cheng, Shih-Ping Yang, Ling-Jun Ho, Anna Andersson, Juha Juntunen, Tomi Jdrvinen,
Tien-Ping Tsao, Ting-Yi Juan, Deh-Ming Chang, Séverine Vandevoorde, Didier M. Lambert,
Sun-Yran Chang and Jenn-Haung Lai Jeffrey C. Jerman and Darren Smart
Contents of Volume 66
Suppression of mitogen-activated protein kinase GENE EXPRESSION AND DEVELOPMENT
phosphatase-1 (MKP-1) by heparin in vascular
Contribution of the Ah receptor to the phenolic anti-
smooth muscle cells
oxidant-mediated expression of human and rat UDP-
Yong Zhao, Weiqun Xiao and
glucuronosyltransferase UGT1A6 in Caco-2 and rat
Douglas M. Templeton
hepatoma 5L cells
Peter A. Miinzel, Stephan Schmohl, Felicitas Buckler,
Generation of oxidant stress in cultured endothelial
cells by methylene blue: protective effects of glucose Jan Jaehrling, Frank T. Raschko,
Christoph Kohle and Karl Walter Bock
and ascorbic acid
James M. May, Zhi-chao Qu and
Richard R. Whitesell INFLAMMATION AND IMMUNOPHARMACOLOGY
a-Lipoic acid decreases thiol reactivity of the insulin
Functional calcium coupling with the human meta-
receptor and protein tyrosine phosphatase 1B in 3T3-
botropic glutamate receptor subtypes 2 and 4 by
L1 adipocytes
stable co-expression with a calcium pathway facilitat-
Kyung-Joo Cho, Hadi Moini, Hee-Kyung Shon,
ing G-protein chimera in Chinese hamster ovary
An-Sik Chung and Lester Packer
cells
Dianne Kowal, Stanley Nawoschik,
Rafal Ochalski and John Dunlop CARDIOVASCULAR AND PULMONARY PHARMACOLOGY
P-selectin as a candidate target in atherosclerosis
Tom J.M. Molenaar, Jaap Twisk, Sonja A.M. de Haas,
(CHEMOTHERAPY AND METABOLIC INHIBITORS
Niels Peterse, Bram J.C.P. Vogelaar,
Methionine restriction selectively targets thymidy-
Steven H. van Leeuwen, Ingrid N. Michon,
late synthase in prostate cancer cells
Theo J.C. van Berkel, Johan Kuiper and
Shan Lu, George L. Chen, Chengxi Ren, Erik A.L. Biessen
Bernard Kwabi-Addo and Daniel E. Epner
GASTROINTESTINAL AND RENAL PHARMACOLOGY
Inhibition of osteoclastogenesis by a phosphodiester-
ase 4 inhibitor XT-611 through synergistic action Inhibition of markers of hepatic stellate cell activa-
with endogenous prostaglandin E, tion by the hormone relaxin
Hideomi Yamagami, Tatsuo Nishioka, Eiji Ochiai, Robert G. Bennett, Kusum K. Kharbanda and
Kazuyo Fukushima, Masaaki Nomura, Shohei Kasugai, Dean J. Tuma
Shuzo Moritani, Koichi Yokogawa and
Ken-ichi Miyamoto
Erratum
Erratum to “Deregulation of gene expression in fetal
Potentiation of the antimalarial action of chloro-
oocytes exposed to doxorubicin”. [Biochem. Pharm.
quine in rodent malaria by drugs known to reduce
cellular glutathione levels 65 (2003) 1701-1707]
Edmundo Bonilla and Jestis del Mazo
Eric Deharo, Daniel Barkan, Miriam Krugliak,
Jacob Golenser and Hagai Ginsburg
Messenger RNA _ expression profiling of genes 15 September 2003
involved in epidermal growth factor receptor signal-
ling in human cancer cells treated with scanning
array-designed antisense oligonucleotides
Commentary
Amelia K. Petch, Muhammad Sohail, Novel treatment of excitotoxicity: targeted disruption
Marcus D. Hughes, Ibrahim Benter, John Darling, of intracellular signalling from glutamate receptors
Edwin M. Southern and Saghir Akhtar
Michelle M. Aarts and Michael Tymianski
HORMONES AND GROWTH FACTORS MOLECULAR AND CELLULAR PHARMACOLOGY
Long-term exposure to f-hexachlorocyclohexane Lactonase and lactonizing activities of human serum
(B-HCH) promotes transformation and invasiveness paraoxonase (PON1 ) and rabbit serum PON3
of MCF-7 human breast cancer cells
John F. Teiber, Dragomir I. Draganov and
Enmin Zou and Fumio Matsumura Bert N. La Du
Contents of Volume 66 2455
Antitumor efficacy of FK228, a novel histone deace- 989 Anthracycline secondary alcohol metabolite forma-
tylase inhibitor, depends on the effect on expression tion in human or rabbit heart: biochemical aspects
of angiogenesis factors and pharmacologic implications
Yuka Sasakawa, Yoshinori Naoe, Takahisa Noto, Alvaro Mordente, Giorgio Minotti,
Takeshi Inoue, Tatsuya Sasakawa, Masahiko Matsuo, Giuseppe Ettore Martorana, Andrea Silvestrini,
Toshitaka Manda and Seitaro Mutoh Bruno Giardina and Elisabetta Meucci
Intestinal epithelial cell accumulation of the cancer Effect of polyglutamylation of methotrexate on its
preventive polyphenol ellagic acid—extensive bind- accumulation and the development of resistance in
ing to protein and DNA the protozoan parasite Leishmania
Alexander C Whitley, Gary D. Stoner, Amal El Fadili, Dave Richard,
Michael V. Darby and Thomas Walle Christoph Ktindig and Marc Ouellette
1009 Genistein reduces NF-KB in T lymphoma cells via a
Depletion of Kupffer cell function by gadolinium
caspase-mediated cleavage of IkBa
chloride attenuates thioacetamide-induced hepato-
toxicity. Expression of metallothionein and HSP70 Dwayne M. Baxa and Fayth K. Yoshimura
David Andrés, Isabel Sdnchez-Reus,
NEUROSCIENCE
Mirandeli Bautista and Maria Cascales
Different pharmacological properties of two equipo- 1019 Possible involvement of induction of brain-derived
tent antagonists (Clozapine and Rauwolscine) for neurotrophic factor in the neuroprotective effect of
a 5-phenylpyrimidine derivative
5-HT>, receptors in rat stomach fundus
Kayo Matsumoto, Kyoko Yamamoto, Yasuko Karasawa,
Maria Villazon, Maria José Enguix, Helena Tristan,
Noriko Hino, Atsushi Nakamura, Masayoshi Takahashi,
Maria Angeles Honrubia, José Brea, Saul Maayani,
Hiroaki Araki, Shigeru Okuyama, Tominari Choshi,
Maria Isabel Cadavid and Maria Isabel Loza
Eiichi Sugino, Satoshi Hibino and Makoto Yoshimoto
Enhanced DNA excision repair in CCRF-CEM cells
1025 Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahy-
resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea,
dropyridine (MPTP) neurotoxicity by the novel selec-
quantitated using the single cell gel electrophoresis
tive dopamine D3-receptor partial agonist FAUC 329
(Comet) assay
predominantly in the nucleus accumbens of mice
Takahiro Yamauchi, Yasukazu Kawai and
Frank Boeckler, Andreas Leng, Anna Mura,
Takanori Ueda
Laura Bettinetti, Joram Feldon, Peter Gmeiner
Antioxidant protection of low density lipoprotein by
and Boris Ferger
procyanidins: structure/activity relationships
1033 Inhibition of indoleamine 2,3-dioxygenase activity in
Patricia Andréia Leite da Silva Porto,
IFN-y stimulated astroglioma cells decreases intra-
Jodo Antonio Nave Laranjinha and
cellular NAD levels
Victor Armando Pereira de Freitas
Ross Grant and Vimal Kapoor
Luteolin inhibits the nuclear factor-KB transcrip-
tional activity in Rat-1 fibroblasts (GENE EXPRESSION AND DEVELOPMENT
Sun-Hee Kim, Kum-Joo Shin, Dohan Kim,
1037 Species-specific splicing and expression of angiotensin
Yun-Hee Kim, Myoung Sook Han,
converting enzyme
Taehoon G. Lee, Euikyung Kim,
Xiao-Li Tian and Martin Paul
Sung Ho Ryu and Pann-Ghill Suh
INFLAMMATION AND IMMUNOPHARMACOLOGY
(CCHEMOTHERAPY AND METABOLIC INHIBITORS
1045 Chronic ethanol consumption impairs receptor-
Inhibition of the proteasome activity, a novel mediated endocytosis of MAA-modified albumin by
mechanism associated with the tumor cell apopto- liver endothelial cells
sis-inducing ability of genistein
MichaelJ . Duryee, Lynell W. Klassen,
Aslamuzzaman Kazi, Kenyon G. Daniel, Thomas L. Freeman, Monte S. Willis, Dean J. Tuma
David M. Smith, Nagi B. Kumar and Q. Ping Dou and Geoffrey M. Thiele
Immediate effects of anticancer drugs on mitochon- 1055 Role of cyclooxygenase-2, but not cyclooxygenase-1,
drial oxygen consumption on type II collagen-induced arthritis in DBA/1] mice
Abdul-Kader Souid, Kirk A. Tacka, Takehiro Ochi, Yoshitaka Ohkubo
Karen A. Galvan and Harvey S. Penefsky and Seitaro Mutoh
2456 Contents of Volume 66
1061 Preventive effect of bis-eugenol, a eugenol ortho MOLECULAR AND CELLULAR PHARMACOLOGY
dimer, on lipopolysaccharide-stimulated nuclear
1127 Different antioxidant effects of polyphenols on lipid
factor kappa B activation and inflammatory cytokine
peroxidation and hydroxyl radicals in the NADPH-,
expression in macrophages
Fe-ascorbate- and Fe-microsomal systems
Yukio Murakami, Masao Shoji,
Sarka Ozgovd, Josef Hefmdnek and Ivan Gut
Shigemasa Hanazawa, Shoji Tanaka and
Seiichiro Fujisawa 1139 Rutinoside at C7 attenuates the apoptosis-inducing
activity of flavonoids
Yen-Chou Chen, Shing-Chuan Shen and Hui-Yi Lin
CARDIOVASCULAR AND PULMONARY PHARMACOLOGY
1151 Taxol- and okadaic acid-induced destabilization of
1067 Pharmacological and biochemical characterization of
bcl-2 mRNA is associated with decreased binding of
the beta-adrenergic signal transduction pathway in
proteins to a bcl-2 instability element
different segments of the respiratory tract
Sumita Bandyopadhyay, Tapas K. Sengupta,
Getu Abraham, Claudia Kottke, Stefan Dhein
Daniel J. Fernandes and Eleanor K. Spicer
and Fritz Rupert Ungemach
1163 Altered expression of regulators of G-protein signal-
1083 H89, an inhibitor of protein kinase A (PKA), stimu-
ing (RGS) mRNAs in the striatum of rats undergoing
lates Na’ transport by translocating an epithelial
dopamine depletion
Na™ channel (ENaC) in fetal rat alveolar type II
epithelium Muriel Geurts, Jean-Marie Maloteaux and
Emmanuel Hermans
Yoshinori Marunaka and Naomi Niisato
Cloning and characterization of guinea pig inter-
leukin-8 receptor
GASTROINTESTINAL AND RENAL PHARMACOLOGY
Julie Catusse, Patrick Faye, Bruno Loillier,
Protective role of heme oxygenase-1 induction in
Béatrice Cremers, Rose-Marie Franck,
carbon tetrachloride-induced hepatotoxicity
Jean-Michel Luccarini, Didier Pruneau and
Kiichi Nakahira, Toru Takahashi,
Jean-Luc Paquet
Hiroko Shimizu, Kyoichiro Maeshima,
Stability of the new prodrug 9-aminocamptothecin
Kenji Uehara, Hiromi Fujii, Hideki Nakatsuka,
glucuronide (9A CG) in the presence of human serum
Masataka Yokoyama, Reiko Akagi
and Kiyoshi Morita albumin
Zeljko M. Prijovich, Yu-Lin Leu and Steve R. Roffler
1107 Decreased activity of basolateral organic ion trans-
ports in hyperuricemic rat kidney: roles of organic 1189 Decoy oligodeoxynucleotides targeting NF-kappaB
ion transporters, rOAT1, rOAT3 and rOCT2 transcription factors: induction of apoptosis in human
primary osteoclasts
Yasushi Habu, Ikuko Yano, Ayako Takeuchi,
Hideyuki Saito, Masahiro Okuda, Letizia Penolazzi, Elisabetta Lambertini,
Atsushi Fukatsu and Ken-ichi Inui Monica Borgatti, Roberta Piva, Mauro Cozzani,
Ilaria Giovannini, Rosalba Naccari,
1115 Expression of vanilloid receptors in rat gastric epithe-
Giuseppe Siciliani and Roberto Gambari
lial cells: role in cellular protection
Shinichi Kato, Eitaro Aihara, Akio Nakamura,
Hong Xin, Hirofumi Matsui, Kazuhiro Kohama
CHEMOTHERAPY AND METABOLIC INHIBITORS
and Koji Takeuchi
1199 3-Substituted-5-aziridinyl-1-methylindole-4,7-diones
as NOQO1-directed antitumour agents: mechanism of
activation and cytotoxicity in vitro
1 October 2003 Mohammed Jaffar, Roger M. Phillips, Kaye J. Williams,
Ibrahim Mrema, Christian Cole, Natasha S. Wind,
Timothy H. Ward, Ian J. Stratford and
Adam V. Patterson
Commentary
1123 Compared pharmacological characteristics in humans 1207 Tumor acidity, ion trapping and chemotherapeutics.
of racemic cetirizine and levocetirizine, two hista- I. Acid pH affects the distribution of chemotherapeu-
mine H,-receptor antagonists tic agents in vitro
Jean-Paul Tillement, Bernard Testa and Brent P. Mahoney, Natarajan Raghunand,
Francoise Brée Brenda Baggett and Robert J. Gillies
Contents of Volume 66 2457
1219 Tumor acidity, ion trapping and chemotherapeutics. 1297 Inhibition of bleomycin-induced cell death in rat
II]. pH-dependent partition coefficients predict alveolar macrophages and human lung epithelial cells
importance of ion trapping on pharmacokinetics of by ambroxol
weakly basic chemotherapeutic agents
Jun Sik Hong, Hyun Hee Ko, Eun Sook Han and
Natarajan Raghunand, Brent P. Mahoney and Chung Soo Lee
Robert J. Gillies
GASTROINTESTINAL AND RENAL PHARMACOLOGY
GENE EXPRESSION AND DEVELOPMENT 1307 The preferential homing of a platelet derived growth
factor receptor-recognizing macromolecule to fibro-
1231 Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin
blast-like cells in fibrotic tissue
(TCDD) with induced adipocyte differentiation in
Leonie Beljaars, Betty Weert, Albert Geerts,
mouse embryonic fibroblasts (MEFs) involves tyro-
Dirk K.F. Meijer and Klaas Poelstra
sine kinase c-Src
Christoph F.A. Vogel and Fumio Matsumura
15 October 2003
1245 Immunoblot analysis and immunohistochemical
characterization of CYP2A expression in human
olfactory mucosa Proceedings from 5th meeting, Luxembourg,
Ying Chen, Yi-Qing Liu, Ting Su, Xiang Ren, Li Shi, 29 January—1 February, 2003
Dazi Liu, Jun Gu, Qing-Yu Zhang and Xinxin Ding Apoptosis — from Signalling Pathways to
Therapeutic Tools
INFLAMMATION AND IMMUNOPHARMACOLOGY
1253 Suppression of dextran sodium sulfate-induced colitis
Editorial
in mice by zerumbone, a subtropical ginger sesquiter-
1319 Apoptosis 2003—from signalling pathways to thera-
pene, and nimesulide: separately and in combination
peutic tools
Akira Murakami, Ryohei Hayashi, Takuji Takana,
Ki Han Kwon, Hajime Ohigashi and Ratu Safitri
MITOCHONDRIA AS REGULATORS OF APOPTOSIS
1263 Involvement of protein kinase Cd and extracellular
1321 Mitochondrion-dependent caspase activation by the
signal-regulated kinase-2 in the suppression of micro-
HIV-1 envelope
glial inducible nitric oxide synthase expression by
N-[3,4-dimethoxycinnamoyl]-anthranilic acid (trani- Thomas Roumier, Maria Castedo, Jean-Luc Perfettini,
Karine Andreau, Didier Meétivier, Naoufal Zamzami
last)
and Guido Kroemer
Michael Platten, Katrin Eitel, Jorg Wischhusen,
Johannes Dichgans and Michael Weller 1331 Mitochondrial state 3 to 4 respiration transition dur-
ing Fas-mediated apoptosis controls cellular redox
1271 Effects of wogonin, a plant flavone from Scutellaria
balance and rate of cell death
radix, on skin inflammation: in vivo regulation of
inflammation-associated gene expression Oren Tirosh, Anna Aronis and J. Andr’s Melendez
Yeon Sook Chi, Hyun Lim, Haeil Park and 1335 Regulation of endoplasmic reticulum Ca** dynamics
Hyun Pyo Kim by proapoptotic BCL-2 family members
Scott A. Oakes, Joseph T. Opferman, Tullio Pozzan,
Stanley J. Korsmeyer and Luca Scorrano
CARDIOVASCULAR AND PULMONARY PHARMACOLOGY
1279 Effect of nitric oxide and nitroxide SOD-mimic on
the recovery of isolated rat heart following ischemia
APOPTOTIC SIGNAL TRANSDUCTION PATHWAYS
and reperfusion
1341 Raf and the road to cell survival: a tale of bad spells,
Azik Hoffman, Sara Goldstein, Amram Samuni,
ring bearers and detours
Joseph B. Borman and Herzl Schwalb
Jakob Troppmair and UIf R. Rapp
1287 Quercetin protects the hydrogen peroxide-induced
apoptosis via inhibition of mitochondrial dysfuntion 1347 Molecular mechanisms underlying WOX1 activation
in H9c2 cardiomyoblast cells during apoptotic and stress responses
Channy Park, Hong-Seob So, Chang-Ho Shin, Nan-Shan Chang, Joan Doherty, Amy Ensign,
Seung-Hwa Baek, Byung-Soon Moon, Sun-Ho Shin, Jennifer Lewis, John Heath, Lori Schultz,
Ho-Seob Lee, Dong-Wook Lee and RaeKil Park Shur-Tzu Chen and Udo Oppermann
Contents of Volume 66
OVARIAN CELL DEATH CASPASES
1355 Alternative pathways of ovarian apoptosis: death for life 1453 Non-apoptotic functions of caspases in cellular
proliferation and differentiation
A. Amsterdam, R. Sasson, I. Keren-Tal, D. Aharoni,
A. Dantes, E. Rimon, A. Land, T. Cohen, Christian Schwerk and Klaus Schulze-Osthoff
Y. Dor and L. Hirsh
1459 Apoptosis in the normal and inflamed airway epithe-
1363 Basic fibroblast growth factor (bFGF) regulation of lium: role of zinc in epithelial protection and procas-
the plasma membrane calcium ATPase (PMCA) as pase-3 regulation
part of an anti-apoptotic mechanism of action
Ai Q. Truong-Tran, Dion Grosser,
John J. Peluso Richard E. Ruffin, Chiara Murgia
and Peter D. Zalewski
INHIBITORS AND ACTIVATORS OF APOPTOSIS 1469 In the cut and thrust of apoptosis, serine proteases
come of age
1371 Potentiation of cellular antioxidant capacity by Bcl-2:
Catherine Stenson-Cox, Una FitzGerald
implications for its antiapoptotic function
and Afshin Samali
Jung-Hee Jang and Young-Joon Surh
1381 Peroxisome proliferator-activated receptor y (PPARy)
TRANSCRIPTIONAL AND Post- TRANSCRIPTIONAL
ligands as bifunctional regulators of cell proliferation
REGULATION OF APOPTOSIS
Hye-Kyung Na and Young-Joon Surh
1475 Induction of apoptosis by curcumin: mediation by
1393 Pleiotropic anti-apoptotic activity of glucocorticoids glutathione S-transferase P1-1 inhibition
in ovarian follicular cells
Annelyse Duvoix, Franck Morceau, Sylvie Delhalle,
R. Sasson and A. Amsterdam Martine Schmitz, Michael Schnekenburger,
Marie-Madeleine Galteau, Mario Dicato
and Marc Diederich
REGULATORS AS CELL DEATH MEDIATORS
1403 Regulation of proliferation, survival and apoptosis by CELL DEATH AND CARDIOVASCULAR DISEASES
members of the TNF superfamily
1485 Cholesterol crystallization and macrophage apopto-
Upasna Gaur and Bharat B. Aggarwal
sis: implication for atherosclerotic plaque instability
and rupture
1409 Nuclear factor-kappa B plays a central role in tumour
necrosis factor-mediated liver disease Yong-Jian Geng, Jane Ellen Phillips,
R. Preston Mason and
Karen Heyninck, Andy Wullaert and Rudi Beyaert
S. Ward Casscells
1417 Slowly getting a clue on CD95 ligand biology
1493 Regulation of smooth muscle cell growth, function
Andreas Linkermann, Jing Qian and Ottmar Janssen
and death in vitro by activated mast cells—a potential
1427 TWE-PRIL; a fusion protein of TWEAK and APRIL mechanism for the weakening and rupture of athero-
sclerotic plaques
Geertruida M. Kolfschoten, Bérengére Pradet-Balade,
Michael Hahne and Jan Paul Medema Markus J. Leskinen, Petri T. Kovanen and
Ken A. Lindstedt
APOPTOSIS IN HUMAN PATHOLOGIES
GLUTATHIONE AND APOPTOSIS
1433 Apoptotic signal transduction pathways in diabetes
1499 The changing faces of glutathione, a cellular prota-
Thomas Mandrup-Poulsen
gonist
1441 The putative role of apoptosis-modified histones for
Alfonso Pompella, Athanase Visvikis,
the induction of autoimmunity in Systemic Lupus
Aldo Paolicchi, Vincenzo De Tata
Erythematosus
and Alessandro F. Casini
Christoph Gabler, Joachim R. Kalden and Hanns-Martin
1505 Anti-apoptotic effect of HIV protease inhibitors via
Lorenz
direct inhibition of calpain
1447 The prodigiosins, proapoptotic drugs with anticancer
Lina Ghibelli, Fabio Mengoni, Miriam Lichtner,
properties Simona Coppola, Milena De Nicola,
Ricardo Pérez-Tomds, Beatriz Montaner, Antonio Bergamaschi, Claudio Mastroianni
Esther Llagostera and Vanessa Soto-Cerrato and Vincenzo Vullo