Advances in Bladder Research PDF
Preview Advances in Bladder Research
ADVANCES IN BLADDER RESEARCH ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRTTCHEVSKY, Wistar Institute ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research RODOLFO PAOLETTI, University of Milan Recent Volumes in this Series Volume 454 OXYGEN TRANSPORT TO TISSUE XX Edited by Antal G. Hudetz and Duane F. Bruley Volume 455 RHEUMADERM: Current Issues in Rheumatology and Dermatology Edited by Carmel Mallia and Jouni Uitto Volume 456 RESOLVING THE ANTIBIOTIC PARADOX: Progress in Understanding Drug Resistance and Development of New Antibiotics Edited by Barry P. Rosen and Shahriar Mobashery Volume 457 DRUG RESISTANCE IN LEUKEMIA AND LYMPHOMA III Edited by G. J. L. Kaspers, R. Pieters, and A. J. P. Veerman Volume 458 ANTIVIRAL CHEMOTHERAPY 5: New Directions for Clinical Application and Research Edited by John Mills, Paul A. Volberding, and Lawrence Corey Volume 459 IMPACT OF PROCESSING ON FOOD SAFETY Edited by Lauren S. Jackson, Mark G. Knize, and Jeffrey N. Morgan Volume 460 MELATONIN AFTER FOUR DECADES Edited by James Olcese Volume 461 CYTOKINES, STRESS, AND DEPRESSION Edited by Robert Dantzer, Emmanuele Wollman, and Raz Yirmiya Volume 462 ADVANCES IN BLADDER RESEARCH Edited by Laurence S. Baskin and Simon W. Hay ward Volume 463 ENZYMOLOGY AND MOLECULAR BIOLOGY OF CARBONYL METABOLISM 7 Edited by Henry Weiner, Edmund Maser, David W. Crabb, and Ronald Lindahl Volume 464 CHEMICALS VIA HIGHER PLANT BIOENGINEERLNG Edited by Fereidoon Shahidi, Paul Kolodziejczyk, John R. Whitaker, Agustin Lopez Munguia, and Glenn Fuller A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher. ADVANCES IN BLADDER RESEARCH Edited by Laurence S. Baskin and Simon W. Hayward Department of Urology University of California, San Francisco Springer Science+Business Media, LLC Proceedings of the International Bladder Research Congress, held April 23-25, 1998, in San Francisco, California ISBN 978-1-4613-7147-2 ISBN 978-1-4615-4737-2 (eBook) DOI 10.1007/978-1-4615-4737-2 ©1999 Springer Science+Business Media New York Originally published by Kluwer Academic /Plenum Publishers in 1999 Softcover reprint of the hardcover 1st edition 1999 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher This book is dedicated to my parents, Fred and Cynthia Baskin PREFACE The aim of Bladder Research Congress, San Francisco, California, April 23-25, 1998, was to provide a forum for authoritative investigators who are actively involved in the various disciplines which define the leading edges of bladder research. It is important for such investigators to continue to meet regularly for the purpose of discussing the latest developments in their individual fields, to analyze the significance of current research, to discuss new tactics for unresolved problems, to critically evaluate current theories, and to develop new theories and approaches as needed. The two and a half day meeting was organized into five half day sessions, with each session encompassing one of five topics: (1) Epithelial-Mesenchymal Interactions; (2) Ex tracellular Matrix and Muscle; (3) Nerves and Pharmacology; (4) Infection and Immunol ogy; and (5) Oncology. Each session was introduced by a moderator followed by five to six invited expert speakers with time for extensive interaction from the participants. Two late-afternoon poster sessions allowed further interactions between investigators. This book documents the proceedings of the Bladder Research Congress. It is organ ized into the five half-day sessions of the meeting with moderators overview and an edited transcription of discussions that followed each presentation. I would like to thank Sarah Burke and the Office of Continuing Medical Education, USCF; Joanne Hayward, Editorial Assistant; and Miriam Escamilla, Administrative Assis tant. I hope you find this resource useful. Laurence S. Baskin, M.D. Program Chair Chief, Pediatric Urology UCSF ix ACKNOWLEDGMENTS Support from the following organisations is gratefully acknowledged; without this funding, the meeting would not have taken place. The National Institutes of Health UCSF Department of Urology * * * Alza Pharmecuticals American Foundation of Urologic Disease Astra Tech, Inc. Bayer Corporation C.R. Bard, Inc. CirconACMI Interstitial Cystitis Association Laborie Medical Technologies Matritech Mentor Urology National Kidney Foundation of Northern California Phone-Poulenc Rorer SmithKline Beecham xi CONTENTS Section I. Epithelial-Mesenchymal Interactions in the Bladder Overview of Epithelial-Mesenchymal Interactions in the Bladder 3 Gerald R. Cunha 1. Uroplakins as Markers ofUrothelial Differentiation 7 Tung-Tien Sun, Feng-Xia Liang, and Xue-Ru Wu 2. Urothelial Tissue Regulation: Unraveling the Role of the Stroma ............ 19 Jennifer Southgate, Patricia Hamden, Peter J. Selby, David F. M. Thomas, and Ludwik K. Trejdosiewicz 3. Creation of Bladder Tissue in Vitro and in Vivo: A System for Organ Replacement ................................................. 31 Anthony Atala 4. Reconstruction of the Urinary Bladder by Auto-Augmentation, Enterocystoplasty, and Composite Enterocystoplasty ................. 43 Mary T. Comer, David F. M. Thomas, Ludwik K. Trejdosiewicz, and Jennifer Southgate 5. Epithelial-Mesenchymal Interactions in the Bladder: Implications for Bladder Augmentation ................................................ 49 Laurence S. Baskin, Simon W. Hayward, Michael S. DiSandro, Ying Wu Li, and Gerald R. Cunha 6. Serosal Thickening, Smooth Muscle Cell Growth, and Phenotypic Changes in the Rabbit Bladder Wall during Outflow Obstruction and Regeneration 63 Saverio Sartore, Marleen Roelofs, Angela Chiavegato, Luigi Faggian, and Rafaella Franch 7. Replicative Senescence in Human Uroepithelial Cells ..................... 83 Jairaj A. Puthenveettil, Melissa S. Burger, and Catherine A. Reznikoff xiii xiv Contents 8. Ultrastructural Smooth Muscle Ontogeny of the Rat Bladder. . . . . . . . . . . . . . . . 93 Hsi-Yang Wu, Laurence S. Baskin, Carrie Blakey, Joseph Goodman, and Gerald R. Cunha Discussion: Epithelial-Mesenchymal Interactions in the Bladder . . . . . . . . . . . . . . . . . . 103 Section II. Muscle and Extracellular Matrix in the Bladder Overview of Muscle and Extracellular Matrix in the Bladder. . . . . . . . . . . . . . . . . . . . . 117 Edward J. Macarak 9. Fetal Bladder Physiology ............................................ 121 Hiep T. Nguyen and Barry A. Kogan 10. Developmental Aspects of the Contractile Smooth Muscle Component in Small Intestinal Submucosa Regenerated Urinary Bladder .................. 129 Bradley P. Kropp 11. Contractile Protein Changes in Urinary Bladder Smooth Muscle following Outlet Obstruction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 137 Samuel Chacko, Michael DiSanto, Chandrakala Menon, Yongmu Zheng, Joseph Hypolite, and Alan J. Wein 12. Calcium Ion Homeostasis in Urinary Bladder Smooth Muscle. . . . . . . . . . . . . . . 155 Stephen A. Zderic, Chao liang Gong, Mike Desanto, Joseph Hypolite, Joel Hutcheson, Alan J. Wein, and Samuel Chacko 13. Cyclooxygenase-2: A Key Regulator of Bladder Prostaglandin Formation 171 John M. Park, Jiirgen B. Schnermann, and Josephine P. Briggs 14. Role of Angiotensin II in Bladder Smooth Muscle Growth and Function 183 Earl Y. Cheng, Robert S. Decker, and Chung Lee 15. New Concepts on the Normal and Abnormal Developing Bladder . . . . . . . . . . . . 193 Ellen Shapiro 16. Biochemical and Physiological Characterization of the Urinary Bladder in Ehlers-Danlos Syndrome ....................................... 201 Catherine M. Deveaud, William A. Kennedy II, Stephen A. Zderic, and Pamela S. Howard 17. The Role of Collagen in Bladder Filling ................................ 215 Edward J. Macarak and Pamela S. Howard Discussion: Muscle and Extracellular Matrix in the Bladder 225 Section III. Nerves and Pharmacology in the Bladder Overview of Nerves and Pharmacology in the Bladder. .. . . . . . . . . . . .. . .. . . . . . . . . 237 Robert M. Levin
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