ABC of prostate cancer PDF
Preview ABC of prostate cancer
Prostate Cancer Prostate Cancer EDITEDBY Prokar Dasgupta ConsultantUrologicalSurgeon DepartmentofUrology King’sCollegeLondon Guy’sandStThomas’HospitalNHSFoundationTrust London,UK Roger S. Kirby ConsultantUrologist TheProstateCentre,London,UK Foreword by Peter T. Scardino A John Wiley & Sons, Ltd., Publication Thiseditionfirstpublished2012©2012byBlackwellPublishingLtd. BlackwellPublishingwasacquiredbyJohnWiley&SonsinFebruary2007.Blackwell’spublishingprogramhasbeenmergedwithWiley’s globalScientific,TechnicalandMedicalbusinesstoformWiley-Blackwell. 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LibraryofCongressCataloging-in-PublicationData ABCofprostatecancer/editedbyProkarDasgupta,RogerS.Kirby;forewordbyPeterT.Scardino.–1sted. p.;cm.--(ABCseries) Includesbibliographicalreferencesandindex. ISBN-13:978-1-4443-3437-1(pbk.:alk.paper)ISBN-10:1-4443-3437-9(pbk.:alk.paper) 1.Prostate–Cancer.I.Dasgupta,Prokar.II.Kirby,R.S.(RogerS.)III.Series:ABCseries(Malden,Mass.) [DNLM:1.ProstaticNeoplasms.WJ762] RC280.P7A232012 616.99(cid:2)463–dc23 2011015319 AcataloguerecordforthisbookisavailablefromtheBritishLibrary. Thisbookispublishedinthefollowingelectronicformats:ePDF9781444346909;ePub9781444346916;Mobi9781444346923 Setin9.25/12MinionbyLaserwordsPrivateLimited,Chennai,India 1 2012 Contents Contributors,vii Foreword,ix 1 AppliedAnatomyoftheProstate,1 PrasannaSooriakumaran,Karl-DietrichSievert,AbhishekSrivastavaandAshutoshTewari 2 PathologyofProstateCancer,5 MuraliVarmaandAshishChandra 3 BiologyofProstateCancer,8 R.WilliamG.WatsonandJohnM.Fitzpatrick 4 ProstateCancerDiagnosis,11 RobinWeston,AnthonyJ.CostelloandDeclanG.Murphy 5 ImagingofProstateCancer,14 JamesHallsandUdayPatel 6 ScreeningforProstateCancer,18 RichardJ.BryantandFreddieC.Hamdy 7 ActiveSurveillance,22 JudithDockray,PardeepKumar,LarsHolmbergandGordonMuir 8 OpenRadicalProstatectomy,25 WimvanHauteandHeinvanPoppel 9 LaparoscopicRadicalProstatectomy,29 PardeepKumarandDeclanCahill 10 RoboticRadicalProstatectomy,33 BenChallacombeandJimPeabody 11 ProstateBrachytherapy,37 PeterAcherandRickPopert 12 HIFU,40 LouiseDickinson,HashimU.AhmedandMarkEmberton 13 CryotherapyforProstateCancer,44 AlastairHendersonandJohnDavies 14 AdvancesinExternalBeamRadiotherapy,48 DavidLandau,NadiaWalshandAsadQureshi 15 RecentAdvancesinHormonalTherapy,51 HeatherPayne,ReenaDavdaandMarkR.Feneley v vi CONTENTS 16 ManagementofCastration-ResistantProstateCancer,54 RogerS.Kirby,ProkarDasguptaandJohnM.Fitzpatrick 17 ImmunologyofProstateCancer,57 OussamaElhage,ChristineGalustian,RichardSmithandProkarDasgupta 18 NewApproachestoProstateCancer,63 MeganS.Schober,RogerS.KirbyandProkarDasgupta Index,67 Contributors PeterAcher MarkEmberton SpecialistRegistrarinUrology,Guy’sandStThomas’HospitalNHS ProfessorofInterventionalOncology,UniversityCollegeLondonand FoundationTrust,London,UK HonoraryConsultantUrologicalSurgeon,UniversityCollegeHospital London,London,UK HashimU.Ahmed MRCFellowinUro-oncologyandClinicalLecturerinUrology,Divisionof MarkR.Feneley SurgeryandInterventionalSciences,UniversityCollegeHospitalLondon, ConsultantUrologist,UniversityCollegeHospitalLondon,London,UK London,UK JohnM.Fitzpatrick RichardJ.Bryant ProfessorofSurgery,UCDSchoolofMedicineandMedicalScience,Mater NIHRClinicalLecturerinUrology,NuffieldDepartmentofSurgical MisericordiaeUniversityHospital,UniversityCollegeDublin,Dublin, Sciences,UniversityofOxford,Oxford,UK Ireland DeclanCahill ChristineGalustian ConsultantUrologicalSurgeon,Guy’sandStThomas’HospitalNHS King’sCollegeLondon,London,UK FoundationTrust,London,UK JamesHalls BenChallacombe SpecialistRegistrarRadiology,DepartmentofRadiology,StGeorge’s ConsultantUrologicalSurgeon,Guy’sandStThomas’HospitalNHS HealthcareNHSTrust,London,UK FoundationTrust,London,UK AshishChandra FreddieC.Hamdy ConsultantPathologist,Guy’sandStThomas’HospitalNHSFoundation NuffieldProfessorofSurgery,ProfessorofUrologyandHead,Nuffield Trust,London,UK DepartmentofSurgicalSciences,UniversityofOxford,Oxford,UK AnthonyJ.Costello WimvanHaute ProfessorialFellow,DepartmentofUrology,TheRoyalMelbourneHospital, UrologicalSurgeon,DepartmentofUrology,StRembertHospital,Torhout; ThePeterMacCallumCancerCentre,Melbourne,VIC,Australia StJanHospital,Bruges,Belgium ProkarDasgupta AlastairHenderson ConsultantUrologicalSurgeon,DepartmentofUrology,King’sCollege ConsultantUrologicalSurgeon,MaidstoneandTunbridgeWellsNHSTrust, London,Guy’sandStThomas’HospitalNHSFoundationTrust,London, Maidstone,UK UK LarsHolmberg ReenaDavda ProfessorofCancerEpidemiology,DivisionofCancerStudies,Medical SpecialistRegistrarinClinicalOncology,UniversityCollegeHospital School,King’sCollegeLondon,London,UK London,London,UK RogerS.Kirby JohnDavies ConsultantUrologist,TheProstateCentre,London,UK ConsultantUrologicalSurgeon,UniversityofSurrey,Guildford,UK PardeepKumar LouiseDickinson SpecialistRegistrarinUrologyandIntuitiveFellowinRobotics,Guy’sand ClinicalResearchFellowinUrology,DivisionofSurgeryandInterventional StThomas’HospitalNHSFoundationTrust,London,UK Sciences,UniversityCollegeHospitalLondon,London,UK JudithDockray DavidLandau King’sCollegeLondon,London,UK ConsultantClinicalOncologist,Guy’sandStThomas’HospitalNHS FoundationTrust,London,UK OussamaElhage MedicalResearchCouncilCentreforTransplantation,King’sCollege GordonMuir London,London,UK King’sCollegeLondon,London,UK vii viii Contributors DeclanG.Murphy PrasannaSooriakumaran Uro-Oncologist,ThePeterMacCallumCancerCentre,AssociateProfessorof VisitingFellowinUrology,RoboticProstatectomyandUrologicOncology Urology,UniversityofMelbourne,Melbourne,VIC,Australia Outcomes,JamesBuchananBradyFoundationDepartmentofUrology, WeillCornellMedicalCollege,NewYorkPresbyterianHospital,NewYork, UdayPatel NY,USA ConsultantRadiologist,DepartmentofRadiology,StGeorge’sHealthcare NHSTrust,London,UK AbhishekSrivastava ResearchAssociate,RoboticProstatectomyandUrologicOncology HeatherPayne Outcomes,JamesBuchananBradyFoundationDepartmentofUrology, ConsultantinClinicalOncology,UniversityCollegeHospitalLondon, WeillCornellMedicalCollege,NewYorkPresbyterianHospital,NewYork, London,UK NY,USA JimPeabody AshutoshTewari AttendingUrologistandFellowshipDirectoratHenryFordHealthSystem, RonaldP.LynchProfessorofUrology,Director-LeFrakCenterforRobotics, HenryFordHospital,Detroit,MI,USA Director-ProstateCancerInstitute,JamesBuchananBradyFoundation DepartmentofUrology,WeillCornellMedicalCollege,NewYork RickPopert PresbyterianHospital,NewYork,NY,USA DepartmentofUrology,Guy’sandStThomas’HospitalNHSFoundation Trust,London,UK MuraliVarma ConsultantHistopathologist,UniversityHospitalofWales,Cardiff,UK HeinvanPoppel FullProfessorofUrology,KatholiekeUniversiteit,ChairmanDepartment NadiaWalsh ofUrology,UniversityHospitalGasthuisberg,Leuven,Belgium SuperintendentPlanningRadiographer,Guy’sandSt.Thomas’Hospital NHSFoundationTrust,London,UK AsadQureshi ClinicalFellowinClinicalOncology,Guy’sandStThomas’HospitalNHS R.WilliamG.Watson FoundationTrust,London,UK AssociateProfessorofCancerBiology,UCDSchoolofMedicineandMedical Science,ConwayInstituteofBiomolecularandBiomedicalResearch, MeganS.Schober UniversityCollegeDublin,Dublin,Ireland DepartmentofUrology,WilliamBeaumontSchoolofMedicineatOakland University,RoyalOak,MI,USA RobinWeston DepartmentofUrology,TheRoyalMelbourneHospital,ThePeter Karl-DietrichSievert MacCallumCancerCentre,TheAustralianProstateCancerResearchCentre, ProfessorofUrology,Director,Uro-oncology,Neurourology,Incontinence EpworthRichmondHospital,Melbourne,VIC,Australia andReconstructiveUrology,DepartmentofUrology,Universityof Tu¨bingen,Tu¨bingen,Germany RichardSmith MedicalResearchCouncilCentreforTransplantation,King’sCollege London,London,UK
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