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2012 ACR/ARHP Program Book PDF

420 Pages·2012·13.84 MB·English
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B:8.625 in T:8.375 in S:6.875 in When you have decided a biologic is the next step Choose ENBREL for appropriate moderate to severe RA patients ENBREL provided rapid and sustained efficacy Visit us at iAnC Rp a20ti Reenstpso nwseitsh a tm Woeedke 2r,a Yteea rt 1o, asnedv Yeeraer 3R (ANRI) were1: S:9.875 in T:10.875 in B:11.125 in booth 707 44%, 75%, and 52% for ENBREL + MTX* 19%, 59%, and 33% for MTX only *P<0.001 vs MTX at all timepoints NRI=Nonresponder imputation Indication A AD875" 5" ENBREL is indicated for reducing signs and symptoms, inducing major clinical response, inhibiting the 0 ACR J5" x 10.5" " x 9.87 pacrotigvree RssAio. nE NoBf RstErLu cctaunr able d ianmitiaagtee,d a inn dc oimmpbrionvaitniogn p whiytshi cmael tfhuontcrteioxnat ien (pMaTtXie)n otsr uwsiethd maloondee.r ately to severely 2725 ENEBRO1 8.3TRIM: .1BLEED:LIVE: 6.87 IEinmNcpBluoRdrtEinaLgn tht aSusab feberetcyeu nlIo nssfhiosor mw(TnaB tti)oo, n binaccrteearsiael tsheep sriiss,k ionfv asseirvieo ufsu ningfaelc tiniofencst iloenasd in(sgu tcoh haoss phiitsatloizpalatisomn oosri sd),e aatnhd, infections due to other opportunistic pathogens, and should be discontinued if a patient develops a serious infection or sepsis. Test for latent TB (if positive, start treatment for TB prior to starting ENBREL) and monitor for active TB during treatment. Lymphoma and other malignancies, some fatal, have been reported program in children and adolescents treated with tumor necrosis factor (TNF) blockers, including ENBREL. Please see additional Important Safety Information and Brief Summary of Prescribing Information on the adjacent pages. 7 7/1 TEMPO was a 3-year, multicenter, double-blind, clinical trial of 682 patients with moderately to severely active RA (mean disease duration: 7 years), who had an F inadequate response to at least 1 DMARD excluding MTX. At baseline: patients were ≥18 years of age, MTX-naïve, had an ESR ≥28 mm/hr or CRP ≥20 mg/L, and were J in ACR functional class I, II, or III.1,2 B O O K Call ENBREL Support™ after you prescribe: Pre-meeting Courses: November 9-10, 2012 1-888-4ENBREL oPening leCture and awards, oPening event: November 10, 2012 www.enbrel.com/rheumpro sCientifiC sessions: November 10-14, 2012 B:8.625 in T:8.375 in S:6.875 in Prescription Enbrel® (etanercept) is administered by injection. demyelinating disorders. Cases of transverse myelitis, optic neuritis, multiple sclerosis, Guillain-Barré syndromes, other IMPORTANT SAFETY INFORMATION peripheral demyelinating neuropathies, and new onset or imPortant loCations exacerbation of seizure disorders have been reported in post- SERIOUS INFECTIONS marketing experience with ENBREL therapy. Prescribers should Patients treated with ENBREL are at increased risk for exercise caution in considering the use of ENBREL in patients developing serious infections that may lead to hospitalization with preexisting or recent-onset central or peripheral nervous aCr office . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .102A; Telephone: (202) 249-4001 or death. Most patients who developed these infections were system demyelinating disorders. taking concomitant immunosuppressants such as methotrexate attendee lounge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .ballroom Pre-Function or corticosteroids or were predisposed to infection because of CONGESTIVE HEART FAILURE their underlying disease. ENBREL should not be initiated in the Cases of worsening congestive heart failure (CHF) and, Business Center . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .L Street South Lobby (under escalator) presence of sepsis, active infections, or allergy to ENBREL or rarely, new-onset cases have been reported in patients taking Career Connection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .exhibit Hall (Hall A), booth 945 its components. ENBREL should be discontinued if a patient ENBREL. Caution should be used when using ENBREL in develops a serious infection or sepsis. Reported infections patients with CHF. These patients should be carefully monitored. Child Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Call for Location; Telephone: (202) 249-4008 include: 1) Active tuberculosis (TB), including reactivation of HEMATOLOGIC EVENTS latent TB. Patients with TB have frequently presented with Rare cases of pancytopenia, including aplastic anemia, some Cme/internet Center . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Concourse (near entrance to Hall A) disseminated or extrapulmonary disease. Patients should fatal, have been reported. The causal relationship to ENBREL Coat/Baggage Check . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .registration (Salons G-H-I) be tested for latent TB before ENBREL use and periodically therapy remains unclear. Exercise caution when considering during therapy. Treatment for latent infection should be ENBREL in patients who have a previous history of significant exhibit Hall . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Hall A initiated prior to ENBREL use, 2) Invasive fungal infections, hematologic abnormalities. Advise patients to seek immediate including histoplasmosis, coccidioidomycosis, candidiasis, medical attention if they develop signs or symptoms of blood first aid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .exhibit Hall (Hall A, bottom of escalator) aspergillosis, blastomycosis, and pneumocystosis. Patients dyscrasias or infection. Consider discontinuing ENBREL if graffiti walls . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .exhibit Hall (Hall A) & Grand Lobby wprieths ehnits twopitlhas mdiosssiesm oinr aottehde, r riantvhaesri vteh afunn gloacl ailnizfeecdt, iodniss emasaey. significant hematologic abnormalities are confirmed. Antigen and antibody testing for histoplasmosis may be HEPATITIS B VIRUS REACTIVATION Hotel reservations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .registration (Salons G-H-I) negative in some patients with active infection. Empiric Use of TNF blockers, including ENBREL, has been associated industry-supported symposia information . . . . . . . . . . . . . . . .L Street South Lobby (under escalator) antifungal therapy should be considered in patients at risk for with reactivation of hepatitis B virus (HBV) in chronic carriers invasive fungal infections who develop severe systemic illness, of this virus. The majority of these reports occurred in patients innovation theater . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Hall A, booth 1451 and 3) Bacterial, viral, and other infections due to opportunistic on concomitant immunosuppressive agents, which may also pathogens, including Legionella and Listeria. contribute to HBV reactivation. Exercise caution when lost and found . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .ACr office (102A) considering ENBREL in patients identified as carriers of HBV. The risks and benefits of treatment with ENBREL should be membership Booth . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .registration (Salons G-H-I) carefully considered prior to initiating therapy in patients ALLERGIC REACTIONS 1) with chronic or recurrent infection, 2) who have been exposed Allergic reactions have been reported in <2% of patients in newsroom . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .203A-b; Telephone: (202) 249-4005 to TB, 3) who have resided or traveled in areas of endemic clinical trials of ENBREL. TB or endemic mycoses, or 4) with underlying conditions that nursing mothers’ room . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Salon D IMMUNIZATIONS may predispose them to infections such as advanced or poorly Live vaccines should not be administered to patients on ENBREL. Poster Hall . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Hall b controlled diabetes. Patients should be closely monitored JIA patients, if possible, should be brought up to date with for the development of signs and symptoms of infection all immunizations prior to initiating ENBREL. In patients with Prayer room . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Salon e (east building, Street Level) during and after treatment with ENBREL, including the exposure to varicella virus, consider temporary discontinuation possible development of TB in patients who tested negative recharge areas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . exhibit Hall (Hall A, main aisles), of ENBREL and prophylactic treatment with Varicella Zoster registration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .aASanttldoe nnladsr egGee- HLmo-Ieu (enLtiegnveeg ( lbr 1oa)ollrmoso m Pre-Function) fMLroeyArpm oLlarpIttGheeoNndmAt iaTNn BC a cInpEhdrSii lodorrt ethnoe rina inmtdiaa tlaiigndngoa ltenhsceciereasnp,t y s.po amtiee nftast atl,r ehaatveed bweiethn IAAlimkuUemtT osuOaynnIneMtd iGMbroolUomdbNieeuI slToi nYrm. aauyt odiemvmeluonpe whietpha EtiNtiBs RmEaLy, oacncdu rr.a Trehleys elu pmuasy- S:9.875 in T:10.875 in B:11.125 in tumor necrosis factor (TNF) blockers, including ENBREL. resolve upon withdrawal of ENBREL. Stop ENBREL if lupus-like resource Center . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .L Street bridge (Level 2) In adult clinical trials of all TNF blockers, more cases of syndrome or autoimmune hepatitis develops. lymphoma were seen compared to control patients. The risk of restaurant reservations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Grand Lobby lymphoma may be up to several-fold higher in RA and psoriasis WEGENER’S GRANULOMATOSIS PATIENTS Rheumatology Research Foundation patients. The role of TNF blocker therapy in the development of The use of ENBREL in patients with Wegener’s granulomatosis malignancies is unknown. receiving immunosuppressive agents (e.g., cyclophosphamide) 5K run/walk registration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .registration (Salons G-H-I) is not recommended. Cases of acute and chronic leukemia have been reported in Rheumatology Research Foundation Booth . . . . . . . . . . . . . . .L Street bridge (Level 2) association with postmarketing TNF blocker use in RA and MODERATE TO SEVERE ALCOHOLIC HEPATITIS other indications. The risk of leukemia may be higher in patients Based on a study of patients treated for alcoholic hepatitis, SRdrehiobsenbsuoioomrnnsa ’Sd tleoiolselutocrngtib gylue oRti u .eo .nsn .eg . .ea . .r . . .ch . . . . . .F . . .o . . .u . . .n . . .d . . .a . . .ti . . . . . .o . . .n . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Weraeesgtsi sto torvavetierolrolnoo o(kSk (a 2(l2onnndds F GFlol-ooHor-)rI )) 120 ACR JA AD375" x 10.875"125" 75" x 9.875" wMrEaelNilept Bplhoaa RrnRttEoieAemLd n(. ataPs ipn aepa nrtridp ooi anxdntciimicore enansa-ttkmsesien leyd lt ea 2rrxnei-saofaokmtm lefdiadon) r ats thswkikaoiintinnnh s ct c hasaTenhnN cogcFeuee rlrn d.be( NlrboaMecl kSpceCoornp)s su,h ildaainevticreoel undbd. eifneongr etATtorxhDi aeesVlr escEmv iweRsoereSse rctE e aa cEluciontVoimjoEhenmocN tlwiToiconSh nhley ens p irutaeestp iintoriegrsta .EecNdti BoanRd,E viLen rfisenec p taieotvniee, nnattnss dwi niht ehRa mAda occdlheineri.ac tIanel sshpueattklee rBs’u lso .u .n . .ge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1L 4S1treet ENEBRO 8.TRIM: .BLEED:LIVE: 6.8 hPInae pldfa iatoitfe rnticths eP w arhetopie oinnritttseiadt emd athliegrnaapnyc aiets ≤ 1w8e yreea lrysm ofp ahgoem, aapsp (rHoxoidmgaktienl’ys csilminiiclaarl ttori athlso osef arell pootrhteerd a idnu RltA i ncdliinciactailo tnrsia, lasd. verse events were and non-Hodgkin’s lymphoma). Other cases included rare DRUG INTERACTIONS speaker ready room . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .156 malignancies usually associated with immunosuppression and The use of ENBREL in patients receiving concurrent malignancies that are not usually observed in children and cyclophosphamide therapy is not recommended. The risk of visitor information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Grand Lobby adolescents. Most of the patients were receiving concomitant serious infection may increase with concomitant use of abatacept immunosuppressants. therapy. Concurrent therapy with ENBREL and anakinra is not wheelchairs (complimentary-limited availability) . . . . . . . . . .Information Desk (Grand Lobby) recommended. Hypoglycemia has been reported following NEUROLOGIC EVENTS wi-fi way . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .exhibit Hall (Hall A) Treatment with TNF-blocking agents, including ENBREL, has been initiation of ENBREL therapy in patients receiving medication for diabetes, necessitating a reduction in antidiabetic medication associated with rare (<0.1%) cases of new onset or exacerbation in some of these patients. 7 of central nervous system demyelinating disorders, some 1 special needs F 7/ presenting with mental status changes and some associated Please see adjacent Brief Summary of Prescribing Information. If you require special arrangements, please contact the ACr office (102A); Telephone: (202) 249-4001. J with permanent disability, and with peripheral nervous system emergency Contact information References: 1. Data on file, Pfizer Inc. 2. Klareskog L, van der Heijde D, de Jager JP, et al; for the TEMPO (Trial of Etanercept and Methotrexate with Radiographic Patient Outcomes) study investigators. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled Space is provided on the back of your badge to list name and telephone numbers of your emergency trial. Lancet. 2004;363:675-681. contacts. Please complete this information before inserting your badge in your badge holder. © 2012 Amgen Inc., Thousand Oaks, CA 91320 and Pfizer Inc. All rights reserved. www.enbrel.com/rheumpro 61043-R4-V3 07-12 program B O O K ABOUT THE ANNUAL MEETING Participation Statement This annual meeting is sponsored by the American College of Rheumatology for educational purposes only. The material presented is not intended to represent the only or the best methods appropriate for the medical conditions being discussed, but rather is intended to present the opinions of the authors or presenters, which may be helpful to other healthcare professionals at arriving at their own conclusions and consequent application. Attendees participating in this medical education program do so with full knowledge that they waive any claim they may have against the College for reliance on any information presented during these educational activities. The College does not guarantee, warrant or endorse any commercial products or services. The ACR’s CME purpose is to provide comprehensive education to improve the knowledge and performance of physicians, scientists and other health professionals. The ACR will offer evidence-based educational activities designed to enhance practice performance and improve the quality of care in those with or at risk for arthritis and rheumatic and musculoskeletal diseases. Global Learning Objectives At the conclusion of the 2012 ACR/ARHP annual meeting, participants should be able to: • identify recent developments in the diagnosis and management of patients with rheumatic diseases • outline new technologies for the treatment of rheumatologic problems • describe potential challenges in the delivery of care to patients with rheumatic diseases and to specify possible solutions • utilize new research data to improve the quality of care of patients with rheumatic diseases • summarize recent rheumatology research findings The program is the result of a planning process that identified educational needs to change or enhance the knowledge, competence or performance of rheumatology professionals. The program’s content was derived from both needs assessment and practice gap analysis that took professional activities, practice setting, ABIM recertification requirements and physician attributes into account. Printing of this publication is supported by Amgen, Inc. and Pfizer, Inc. This publication was printed by an FSC validated printer on eco-friendly paper. TABLE OF CONTENTS POLICIES PRE-MEETING PROGRAM Copyright Materials Policy .....................................11 Friday, November 9, 2012 Media ......................................................11 ACR Musculoskeletal Ultrasound Course for Rheumatologists – Embargo Policy ...............................................11 Day One of Two ..............................................20 ACR Certified Rheumatology Coder Course: Unlock the Mystery: MEETING INFORMATION A Roadmap for Rheumatology Coding – Day One of Two ............21 Cell Phones, PDAs & Other Electronic Devices .....................12 ACR Basic Research Conference: Mesenchymal Cells in Rheumatic Diseases: Tissue Erosion/Invasion vs. Fibrosis – Day One of Two ......22 Children ....................................................12 ACR Clinical Research Conference: Pain Research: New Methods Child Care ...................................................12 and Challenges – Day One of Two ...............................22 Nursing Mothers’ Room .......................................12 ACR/ABIM Maintenance of Certification Learning Session – Exhibit Hall ..................................................12 2012 Update in Rheumatology .................................21 Meeting Room Capacity/Important First Safety Information ..........12 Saturday, November 10, 2012 Photograpy and Videotaping ...................................12 ACR Musculoskeletal Ultrasound Course for Rheumatologists – Name Badges ................................................12 Day Two of Two ..............................................23 No Smoking .................................................12 ACR Review Course ...........................................24 MEETING NAVIGATION GUIDE ACR Basic Research Conference: Mesenchymal Cells in Rheumatic Diseases: Tissue Erosion/Invasion vs. Fibrosis – Day Two of Two ......25 Track Icons ..................................................13 ARHP Clinical Focus Course: Treating the Patient with Session Formats ..............................................13 Osteoarthritis: Interventions, Innovations and Clinical Insights .......26 Abstract Formats .............................................13 CORC Pre-meeting Course for Practice Managers: Helping You Manage A Profitable Practice ..................................27 MEETING SERVICES ACR Clinical Research Conference: Pain Research: New Methods and Challenges – Day Two of Two ...............................27 My Annual Meeting ..........................................15 ACR Certified Rheumatology Coder Course Examination: Resource Center ..............................................15 Unlock the Mystery: A Roadmap for Rheumatology Coding – Membership Booth ...........................................15 Day Two of Two ..............................................29 Lost and Found ...............................................15 Newsroom ..................................................16 ACR/ARHP ANNUAL MEETING Attendee Lounge .............................................16 SCIENTIFIC PROGRAM Announcement Boards ........................................16 Saturday, November 10, 2012 Career Connection ............................................16 ACR/ARHP Opening Lecture and Awards ..........................29 Registration Shuttle Bus .......................................16 Speaker Ready Room ..........................................16 Sunday, November 11, 2012 Wi-Fi Way and Recharge Access .................................16 ACR Sessions Rheumatology Research Foundation Booth .......................17 Modifying Causal Risk Factors that Influence the Incidence of Falls Rheumatology Research Foundation Donors’ Lounge ...............17 by Older Adults ..............................................29 Rheumatology Research Foundation 5K Run/Walk ..................17 Year in Review ...............................................30 Genetics as a Tool for Elucidating Autoimmune Disease SPECIAL OFFERS Pathogenesis ................................................30 SessionSelect ................................................18 Tips for Publishing Your Work in a Peer-Reviewed Medical Journal .....................................................30 What Would Make the Meeting Better ...........................19 Medical Bag .................................................19 ARHP Sessions ARHP First-time Attendee Orientation ............................30 POSTER SESSIONS ARHP Moderators Orientation ..................................30 Poster Session Presenter Instructions ............................19 Meet the Professor Sessions ACR Poster Presenter No-show Policy ............................19 Behçet’s Disease (001) ........................................31 Guided Poster Tours ...........................................19 Controversies in Sjögren’s Syndrome (002) ........................31 Infections with Biologics (003) ..................................31 Pediatrics: Dermatomyositis (004) ...............................31 Pediatrics: Difficult to Treat Juvenile Idiopathic Arthritis (005) ........31 2 2012 Program Book TABLE OF CONTENTS Rheumatoid Arthritis: Biological Agents (006) . . . . . . . . . . . . . . . . . . . . .31 ARHP Networking Event Spondylarthropathy: An Update (007) . . . . . . . . . . . . . . . . . . . . . . . . . . . .31 Networking Forum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37 Systemic Arthritis and Still’s Disease (008) . . . . . . . . . . . . . . . . . . . . . . . .31 ACR Meet the Professor Sessions Systemic Lupus Erythematosus: Central Nervous System (009) . . . . . . .31 Adult Inflammatory Myopathy (011) . . . . . . . . . . . . . . . . . . . . . . . . . . . . .38 Vasculitis Mimics (010) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31 Cutaneous Vasculitis (012) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .38 ACR Workshops Inflammatory Eye Disease/Uveitis (013) . . . . . . . . . . . . . . . . . . . . . . . . . .38 Basic Statistical Concepts for the Medical Researcher (201) . . . . . . . . . .31 Myopathy: Issues in Diagnosis and Treatment (014) . . . . . . . . . . . . . . . .38 Clinical Anatomy and Physical Exam: Essential Tools in Lower Osteoporosis: Novel Treatments (015) . . . . . . . . . . . . . . . . . . . . . . . . . . .38 Extremity Regional Pain Syndromes (202) . . . . . . . . . . . . . . . . . . . . . . . .31 Pediatrics: Periodic Fevers in Children (016) . . . . . . . . . . . . . . . . . . . . . . .38 Dermatopathology of Rheumatic Diseases (203) . . . . . . . . . . . . . . . . . . .31 Polymyalgia Rheumatica (017) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .38 Musculoskeletal Exam Skills I: General Musculoskeletal Pregnancy in Rheumatic Diseases (018) . . . . . . . . . . . . . . . . . . . . . . . . . .38 Examination for Arthritis (204) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31 Systemic Lupus Erythematosus: Novel Treatments (019) . . . . . . . . . . . . .38 ACR Sessions Vitamin D and Bone Health (020) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .38 Advances in the Biology of Aging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31 ACR Sessions CORC FORUM: Achieving Economic Goals in an Era of Healthcare Endoplasmic Reticulum Stress Unfolded Protein Response in Reform . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31 Immunity and Inflammation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .38 New Therapies for Modulating Signaling in Rheumatoid Arthritis . . . . .32 Mechanisms of Pain in Rheumatic Diseases . . . . . . . . . . . . . . . . . . . . . . .38 The Plasticity of T Regulatory Cells and their Role in Autoimmunity . . . . 32 Preoperative Assessment and Perioperative Management Update on Stroke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .32 of the Patient with Rheumatic Disease: What Every Extra-articular Involvement in Rheumatoid Arthritis . . . . . . . . . . . . . . . .32 Rheumatologist Should Know (Clinical Review) . . . . . . . . . . . . . . . . . . . .38 Medical Education: The Year in Review . . . . . . . . . . . . . . . . . . . . . . . . . . .32 ACR Workshops ACR Poster Session A and Poster Tours Designing a Website for Your Practice (208) . . . . . . . . . . . . . . . . . . . . . . .39 Abstracts (#1-724) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .32 Muscle Involvement in Rheumatic Diseases (209) . . . . . . . . . . . . . . . . . .39 Physical Examination Skills for Improved Detection of Synovitis ARHP Session and Cervical Thoracolumbar Disorders (210) . . . . . . . . . . . . . . . . . . . . . .39 ARHP Keynote Address: It’s Not Child’s Play: Growing Up With Renal Histopathology in Systemic Lupus Erythematosus and and Mastering Juvenile Idiopathic Arthritis from the Child’s Vasculitis (211) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39 Perspective . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33 ACR Sessions Rheumatology Research Foundation Special Session Complementary and Alternative Medicine: Evidence-based Oscar S. Gluck, MD, Memorial Lectureship: Bone Wasn’t Options for Arthritis Patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39 Built in a Day: New Insights into Destruction and Repair in Rheumatic Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33 Prospects for Prevention and Cure of Rheumatoid Arthritis . . . . . . . . . .39 The Great Debate: In 2012 what are the Roles of Cyclophosphamide Exhibits and Innovation Theater versus Rituximab in ANCA-Associated Vasculitis . . . . . . . . . . . . . . . . . . .39 See page 316 of a complete listing of Innovation Theater. . . . . . . . . . . . .33 Update on Treatment of Systemic Lupus Erythematosus . . . . . . . . . . . . .39 ACR Workshops ACR Concurrent Abstract Sessions Adult Musculoskeletal Upper Examinations (205) . . . . . . . . . . . . . . . . . .33 Biology and Pathology of Bone and Joint: Osteoarthritis Musculoskeletal Ultrasound (206) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33 (#730-735) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .40 Renal Histopathology in Systemic Lupus Erythematosus and Cytokines, Mediators, and Gene Regulation I (#736-740) Vasculitis (207) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33 Includes 2011 Lee C. Howley, Sr. Prize for Arthritis Research Introductory Talk I . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .40 ACR Plenary Session I: Discovery 2012 Epidemiology and Health Services Research I: Epidemiology Abstracts (#725-729) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .33 and Outcomes in Rheumatic Disease (#741-746) . . . . . . . . . . . . . . . . . .41 ARHP Sessions Miscellaneous Rheumatic and Inflammatory Diseases: Hands: Non-Surgical Management and Bracing – What You Periodic Fever Syndromes (#747-752) . . . . . . . . . . . . . . . . . . . . . . . . . . .41 Don’t Know Can Hurt You . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Muscle Biology, Myositis and Myopathies: Classification, New Medication Developments in Rheumatology . . . . . . . . . . . . . . . . . .37 Treatment and Outcome in Idiopathic Inflammatory Myopathies (# 753-758) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .42 Rheumatic Disease Update: Vasculitis . . . . . . . . . . . . . . . . . . . . . . . . . . . .37 Pediatric Rheumatology: Clinical and Therapeutic Disease I: The 5A Approach to Physical Activity Counseling for Juvenile Idiopathic Arthritis I (#759-764) . . . . . . . . . . . . . . . . . . . . . . . . .42 Arthritis Patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37 Rheumatoid Arthritis – Clinical Aspects I: Risk Factors and ACR Session Prediction of Rheumatoid Arthritis (#765-770) . . . . . . . . . . . . . . . . . . . .43 ACR Knowledge Bowl – Preliminary Round . . . . . . . . . . . . . . . . . . . . . . . .37 2012 Program Book 3 TABLE OF CONTENTS Rheumatoid Arthritis Treatment – Small Molecules, Biologics Psoriatic Arthritis (026) ........................................56 and Gene Therapy: Comparative Efficacy and Novel Treatment Pulmonary Hypertension in the Rheumatic Diseases (027) ...........56 Strategies in Rheumatoid Arthritis (#771-776). . . . . . . . . . . . . . . . . . . . . 44 Rheumatoid Arthritis: Challenging Cases (028) .....................56 Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects Rheumatoid Arthritis: Outcome Measures in Clinical and Treatment: Spondyloarthritis I (#777-782) ....................45 Practice (029) ...............................................56 Systemic Sclerosis, Fibrosing Syndromes and Raynaud’s – Temporal Arteritis (030) .......................................56 Pathogenesis, Animal Models and Genetics (#783-788) .............45 ARHP Sessions ARHP Sessions Income Inequities Are Perilous to People with Arthritis ..............56 Non-pharmacological Management of Fibomyalgia: Your Toolbox .....46 Practice Management: Patients As Partners in Design and Practice Managers: Improving Access and Website Marketing Delivery (Practice Management Series) ..........................56 (Practice Management Series) ..................................46 Rheumatic Disease Update: Inflammatory Eye Disease ..............46 ARHP Concurrent Abstract Sessions Pediatrics: Disease Flares (#861-865). . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 ARHP Concurrent Abstract Sessions Psychological Aspects of Rheumatologic Disease (#866-871) .........57 Foot and Gait Disorders (#789-794) ..............................47 Osteoarthritis (#795-800) ......................................47 Monday, November 12, 2012 ACR Workshops ACR Sessions Dermatopathology of Rheumatic Diseases (212) ...................48 Clinicopathologic Conference: A Patient with Hepatitis C and Inflammatory Polyarticular Arthritis .........................58 Musculoskeletal Exam Skills II: Regional Musculoskeletal Examination of the Neck and Low Back (213) .....................48 Cross-Sectional Imaging Techniques for Rheumatology ..............58 Osteoporosis: Interpreting Dual Energy X-ray Absorptiometry Immune Tolerance: From Theory and Clinical Practice ...............58 and Clinical Risk Factors: The New Fracture Risk Assessment Synovial Immunobiology and Response to Therapy in Algorithm (214) ..............................................48 Rheumatoid .................................................58 Synovial Fluid Analysis and Crystal Identification (215) ..............48 ARHP Sessions ACR Sessions Disparities in the Use of Joint Arthroplasty: A Pervasive Classification and Treatment of Sjögren’s Syndrome ................48 Matter Leading to Inequitable Care (Arthroplasty/Joint Replacement Series) ..........................................58 Metabolic Abnormalities in Autoimmunity ........................48 Incorporating Physician Assistants and Nurse Practitioners Puberty, Adolescence and Rheumatologic Disease .................48 into Rheumatology Practice ....................................59 Thieves’ Market: Show Me Your Best Cases .......................49 Infusion Room Information for Medical Professionals Update on Psoriatic Arthritis and the Spondylarthropathies .........49X (Infusion Series) .............................................59 ACR Concurrent Abstract Sessions New and Better Habits! Facilitating Patient Self-management Fibromyalgia and Soft Tissue Disorders I (#801-806) ................49 with Proven Behavior Change Strategies .........................59 Imaging of Rheumatic Diseases I: Ultrasound and X-ray (#807-812) ....50 ACR Session Metabolic and Crystal Arthropathies: Clinical (#813-818) ............50 ILAR – The Current Rheumatology Workforce Across the Globe .......59 Osteoporosis and Metabolic Bone Disease (#819-824) ..............51 ACR Meet the Professor Sessions Rheumatoid Arthritis – Clinical Aspects II: Long-term Outcome Crystal: Diagnosis and Management of Gout (031) .................60 of Rheumatoid Arthritis, Observational Studies (#825-830) ..........51 Osteoarthritis: Update 2012 (032) ...............................60 Rheumatoid Arthritis Treatment – Small Molecules, Biologics and Gene Therapy: Efficacy and Safety of Novel Entities (#831-836) ......52 Pediatric Rheumatology for Adult Rheumatologists (033) ............60 Systemic Lupus Erythematosus – Clinical Aspects and Treatment I: Pediatrics: Spondylarthritis in Children (034) ......................60 Renal (#837-842) ............................................53 Psoriatic Arthritis (035) ........................................60 Systemic Lupus Erythematosus – Human Etiology and Rheumatoid Arthritis: Difficult Cases (036) ........................60 Pathogenesis I (#843-848) .....................................53 Rheumatoid Arthritis: Difficult Cases (037) ........................60 Systemic Sclerosis, Fibrosing Syndromes, and Raynaud’s – Scleroderma: Systemic Sclerosis (038) ............................60 Clinical Aspects and Therapeutics I (#849-854) ....................54 Scleroderma: Systemic Sclerosis (039) ............................60 Vasculitis: Pathogenesis (#855-860) ..............................55 Vasculitis: Update (040) ........................................60 ACR Meet the Professor Sessions ACR/ARHP Workshops Ankylosing Spondylitis: 2012 Update (021) ........................56 Joint Injections (Knee and Ankle Prosthetics) (216) .................60 Antiphospholipid Syndrome (022) ...............................56 Musculoskeletal Ultrasound (217) ...............................60 Crystal: Diagnosis and Management of Gout (023) .................56 Peripheral Magnetic Resonance Imaging in Rheumatology Immunodeficiency Syndromes (024) .............................56 Practice (218) ...............................................60 Pain: Evaluation and Treatment of Back Pain (025) .................56 X-ray Challenges in Rheumatic Diseases (219) .....................60 4 2012 Program Book TABLE OF CONTENTS ACR Sessions Dermatological Manifestations of Rheumatic Diseases (044) .........70 Epigenetic Factors in Autoimmune Disease ........................60 Hereditary Angioedema (045) ..................................70 New Anticoagulants: What a Hematologist Thinks a Pulmonary Manifestations of Rheumatic Disease (046) ..............70 Rheumatologist Needs to Know! ................................61 Raynaud’s and Digital Ischemia (047) .............................70 Rheumatology Research Foundation Special Session Scleroderma Mimics (048) .....................................70 Memorial Lectureship: Pathogenesis of Rheumatoid Vaccinations for Patients on Biologic Therapies (049) ...............70 Arthritis: The Voyage from Pre-Rheumatoid Arthritis to Joint Vasculitis: Update (050) ........................................70 Destruction .................................................61 ACR Sessions ARHP Sessions Complex Regional Pain Syndrome/Reflex Sympathetic Clinical Trials: Participation and Recruitment ......................61 Dystrophy: Recent Advances, Current Thoughts ...................70 Infusion Reactions: Management and Prevention Innovation in Musculoskeletal Curriculum Development: (Infusion Series) .............................................61 Lessons from New Medical Schools .............................70 Issues in the Management of Rheumatic Disease in Pediatric Rheumatology Town Hall Meeting .......................71 Patients Undergoing Joint Replacement (Arthroplasty/Joint Scleroderma Bowel Disease: From Top to Bottom (Clinical Review) ....71 Replacement Series) ..........................................61 Rheumatic Disease Update: Gout ................................61 ACR/ARHP Workshops Histopathology of Vasculitis (222) ...............................71 ACR Sessions Joint Injections (Shoulder and Wrist Prosthetics) (223) ..............71 Creating an Efficient Rheum Practice .............................61 MRI in the Diagnosis and Management of Spondylarthritis: Legislative Update from Capitol Hill ..............................62 A Clinician’s Guide (224) .......................................71 Update on Safety Issues in the Treatment of Rheumatic Diseases – From the Food and Drug Administration and Beyond .....62 ACR Sessions Curbside Consults – Ask the Professors ...........................71 Rheumatology Research Foundation Special Session Macrophage and Dendritic cell Heterogeneity in Tissue ACR REF Special Session: Clinician Scholar Educator Presentations ....62 Inflammation and Fibrosis .....................................71 ACR/ARHP Poster Session B, Thieves’ Market Posters and Mechanotransduction in Bone and Cartilage ......................72 Poster Tours Neuropsychiatric Lupus in Children and Adolescents ................72 Abstracts (#872-1592) .........................................62 Osteoporosis: From Bisphosphonates and Beyond. . . . . . . . . . . . . . . . . . 72 Exhibits and Innovation Theater ACR Concurrent Abstract Sessions See page 316 of a complete listing of Innovation Theater. ............63 Cell-cell Adhesion, Cell Trafficking and Angiogenesis (#1599-1603) Includes 2011 Lee C. Howley, Sr. Prize for Arthritis Research ARHP Session Introductory Talk II ...........................................72 Distinguished Lecturer: Unraveling the “Go-Gene” .................63 Epidemiology and Health Services Research II: Epidemiologic Risk Factors in the Development of Rheumatic Disease ACR Workshops (#1604-1609) ................................................73 Musculoskeletal Exam Skills III: Regional Musculoskeletal Genetics and Genomics of Rheumatic Diseases (#1610-1615) ........73 Examination of the Shoulder and Knee (220) ......................63 Imaging of Rheumatic Diseases II: Magnetic Resonance Osteoporosis: Interpreting Dual Energy X-ray Absorptiometry Imaging (#1616-1621) ........................................74 and Clinical Risk Factors: The New Fracture Risk Assessment Algorithm (221) ..............................................63 Infection-related Rheumatic Disease (#1622-1627) .................75 Metabolic and Crystal Arthropathies: Basic Science (#1628-1633) .....76 ACR Plenary Session II: Discovery 2012 Rheumatoid Arthritis – Animal Models (#1634-1639) ...............76 (Abstracts #1593-1598) ........................................64 Rheumatoid Arthritis Treatment – Small Molecules, Biologics ACR Sessions and Gene Therapy: Safety I (#1640-1645) ........................77 ACR Knowledge Bowl – Final Round ..............................68 Systemic Lupus Erythematosus – Clinical Aspects and Career Opportunities in Rheumatology: Making a Choice ............69 Treatment II: Clinical Aspects/Pregnancy (#1646-1651) .............78 New Developments in Systemic Juvenile Idiopathic Vasculitis: Clinical Trials (#1652-1657) ............................78 Arthritis Management ........................................69 ARHP Sessions The Connected Rheumatology Practice: Electronic Health Demystifying the Study Section: How Grants Are Record and Social Media Implementation and Customization ........69 Reviewed and Scored .........................................79 ARHP Networking Event Depression in Rheumatic Diseases ...............................80 Networking at Noon ..........................................69 Minimizing Falls in Geriatric Rheumatic Populations ................80 Total Knee Arthroplasty Rehabilitation: Optimizing Functional ACR Meet the Professor Sessions Outcomes Through Examination of Patient Factors, Practice Ankylosing Spondylitis: 2012 Update (041) ........................70 Variation and Best Practice Recommendations (Arthroplasty/ Basic Immunology for Clinical Rheumatologists (042) ...............70 Joint Replacement Series) .....................................80 Challenging Cases in Osteoporosis Management (043) ..............70 2012 Program Book 5 TABLE OF CONTENTS ACR Workshops ARHP Concurrent Abstract Session Getting Electronic Health Records Right (225) .....................80 Care of Patients With Rheumatoid Arthritis (#1718-1723) ...........89 Musculoskeletal Ultrasonography: Basic (226) .....................80 ACR Study Groups .............................................90 Patient Questionnaires: Multi-Dimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data 3 Tuesday, November 13, 2012 and Beyond Toward a Standard, Scientific, Quantitative ACR Sessions Patient History (227) ..........................................81 Chronic Recurrent Multifocal Osteomyelitis .......................90 Systemic Sclerosis: How to Perform Skin Scores (228) ...............81 Molecular and Cellular Basis of Tissue Homing .....................91 ACR Sessions Update on Immune Mediated Glomerular Disease .................91 Aging and the Rheumatic Diseases ..............................81 Rheumatology Research Foundation Special Session Dermatology Topics for Rheumatologists: What You Need to Know ....81 Paul Klemperer, MD Memorial Lectureship: Serum Energetics, Metabolism and Osteoarthritis ........................81 Autoantibodies in Systemic Sclerosis: Usefulness in Diagnosis, Gout and Hyperuricemia: Diseases Beyond the Joint ................81 Clinical Subsetting and Predicting Outcomes ......................91 Preclinical Autoimmunity – Potential for Prevention ................82 ARHP Sessions ACR Concurrent Abstract Sessions Clinical and Epidemiologic Study Designs in Rheumatic Cytokines, Mediators, and Gene Regulation II (#1658-1663). . . . . . . . . . 82 Disease Research ............................................91 Epidemiology and Health Services Research III: Rheumatic Don’t Let the Pink Sheets Make You Blue .........................91 Diseases and Cardiovascular Disease and Risk Assessment Fungal Infections and Tuberculosis in Patients with (#1664-1669) ................................................82 Rheumatologic Disease (Infection Series). . . . . . . . . . . . . . . . . . . . . . . . . 91 Muscle Biology, Myositis and Myopathies: Pathogenesis in ACR Meet the Professors Sessions Idiopathic Inflammatory Myopathies (#1670-1675) ................83 Ankylosing Spondylitis: Disease Modification (061) .................91 Pediatric Rheumatology: Clinical and Therapeutic Disease II: Juvenile Idiopathic Arthritis II (#1676-1681) ......................84 Crystal: Diagnosis and Management of Gout (062) .................92 Rheumatoid Arthritis – Clinical Aspects III: Rheumatoid Arthritis Infections with Biologics (063) ..................................92 and Cardiovascular Disease (#1682-1687) ........................84 Osteoarthritis: Update 2012 (064) ...............................92 Rheumatoid Arthritis – Human Etiology and Pathogenesis I: Pain: Dealing with Patients with Refractory Pain in Early Pathogenesis of Rheumatoid Arthritis (#1688-1693) ...........85 Musculoskeletal and Autoimmune Disorders (065) .................92 Rheumatoid Arthritis Treatment – Small Molecules, Biologics Pediatrics: Juvenile Idiopathic Arthritis for Adult and Gene Therapy: Safety II (#1694-1699) ........................85 Rheumatologists (066) ........................................92 Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects Pregnancy in Rheumatic Diseases (067) ..........................92 and Treatment: Spondyloarthritis II (#1700-1705) .................86 Reactive Arthritis: An Update (068) ..............................92 Systemic Lupus Erythematosus – Clinical Aspects and Treatment III: Scleroderma: Systemic Sclerosis (069) ............................92 Cardiovascular (#1706-1711) ...................................87 Vasculitis: Update (070) ........................................92 Systemic Sclerosis, Fibrosing Syndromes, and Raynaud’s – Clinical Aspects and Therapeutics II (#1712-1717) .................87 ACR/ARHP Workshops Adult Musculoskeletal Lower Examinations (229) ..................92 ACR Meet the Professor Sessions Knee Braces and Foot Orthosis for Knee Osteoarthritis (230) .........92 Adult Inflammatory Myopathy (051) .............................88 Peripheral Magnetic Resonance Imaging in Rheumatology Antiphospholipid Syndrome (052) ...............................88 Practice (231) ...............................................92 Controversies in Sjögren’s Syndrome (053) ........................88 Synovial Fluid Analysis and Crystal Identification (232) ..............92 Dermatological Manifestations of Rheumatic Diseases (054) .........88 Fibromyalgia and Dysautonomia (055) ...........................88 ACR Sessions Pain: Evaluation and Treatment of Back Pain (056) .................88 Advances in Targeting of B cell Survival Factors ....................92 Pediatric Systemic Lupus (057) ..................................88 Systems Immunology. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92 Psoriatic Arthritis (058) ........................................88 ARHP Sessions Rheumatoid Arthritis: Biological Agents (059) .....................88 Hepatitis in Patients with Rheumatologic Disease Systemic Lupus Erythematosus: Difficult to Treat Systemic Lupus (Infection Series) .............................................93 Erythematosus (060) .........................................88 Rheumatic Disease Update: The Approach to Low Back Pain .........93 ARHP Sessions Threats to Validity: Confounding in Rheumatic Disease Research (Research Series) ....................................93 Early Rehabilitation for Hip and Foot Osteoarthritis: Opportunities and Challenges ..................................88 ACR Sessions Novel Approaches to Pain Management in Juvenile Contract Negotiations for Physicians .............................93 Idiopathic Arthritis ...........................................88 Paradigm Shifts in Rheumatoid Arthritis ..........................93 Promoting Participation: Where Is the Field and Where The Guide to Meaningful Use and Beyond ........................93 Do We Go Next? .............................................89 6 2012 Program Book TABLE OF CONTENTS Rheumatology Research Foundation Special Session ACR Sessions Disease Targeted Research .....................................94 Catastrophic Antiphospholipid Syndrome (Clinical Review) ..........102 Osteoimmunology ...........................................102 ARHP Concurrent Abstract Sessions Physical/Occupational Therapy and Exercise in Patients ACR Study Groups ............................................102 with Rhematologic Disease (#2431-2436) ........................94 ACR/ARHP Workshops Programs and Literacy in Patients with Rheumatolgic Clinical Anatomy and Physical Exam: Essential Tools in Diseases (#2437-2442) ........................................94 Upper Extremity Regional Pain Syndromes (235) .................103 ACR/ARHP Poster Session C, MRI in the Diagnosis and Management of Spondyloarthritis: Thieves’ Market Posters and Poster Tours A Clinician’s Guide(236) ......................................103 Abstracts (#1724-2430) ........................................95 Synovial Fluid Analysis and Crystal Identification (237) .............103 Web-based Tools for Enhancing and Managing Teaching Exhibits and Innovation Theater and Clinical Practice (238) ....................................103 See page 316 of a complete listing of Innovation Theater. ............96 ACR Session ACR Session ACR Leadership Town Hall Meeting & Business Meeting ............103 Gouty Inflammation ..........................................96 ACR Sessions ARHP Sessions Approach and Management of Back Pain in Older Adults ...........103 Immunizations in Patients with Rheumatologic Disease Connective Tissue Disease Associated Interstitial Lung Disease ......104 (Infection Series) .............................................96 New Molecules in Joint Biology ................................104 Selection Bias in Rheumatic Disease Research – Risk Factor Paradox and Other Issues .....................................96 Visualizing the Immuno-inflammatory Response ..................104 ACR/ARHP Combined Abstract Session ACR Concurrent Abstract Sessions ACR/ARHP Combined Rehabilitation Abstract Session ACR Late-breaking Abstract Session .............................104 (#2443-2448) ................................................96 Antiphospholipid Syndrome (#2455-2460) .......................104 Epidemiology and Health Services Research IV: Outcomes ACR Workshops and Costs in Rheumatic Disease (#2461-2466) ...................105 Histopathology of Vasculitis (233) ...............................97 Osteoarthritis – Clinical Aspects II: Structural Risks for Joint Injection Techniques (234) .................................97 Osteoarthritis End-points and Potential Treatments (#2467-2472) ...............................................105 ARHP Sessions Pediatric Rheumatology: Clinical and Therapeutic Disease III: A Practical Understanding of Function in Rheumatoid Arthritis: Childhood Systemic Lupus Erythematosus and Other Vasculitides A Multidisciplinary Perspective .................................97 (#2473-2478) ...............................................106 Strategies to Enhance Office Efficiencies and Access to Care Rheumatoid Arthritis – Clinical Aspects IV: Non-biologic Drugs in Rheumatology Practice .....................................97 for Rheumatoid Arthritis: New Insights on Comorbidities and ACR Plenary Session III: Discovery 2012 Adverse Events (#2479-2484) .................................107 Abstracts (#2449-2454) ........................................97 Rheumatoid Arthritis Treatment – Small Molecules, Biologics and Gene Therapy: Safety & Efficacy of Janus Activated-Kinase ACR Sessions (JAK) Inhibitors (#2485-2490) .................................108 Microbiome Influence on Autoimmunity ........................101 Spondyloarthritis and Psoriatic Arthritis – Pathogenesis, Polymyalgia Rheumatica – Recent Advances and Ongoing Questions ...101 Etiology (#2491-2496) .......................................108 Top 10 Compliance Risks Facing Physicians .......................101 Systemic Lupus Erythematosus – Human Etiology and Pathogenesis II (#2497-2502) .................................109 ARHP Networking Event T-cell Biology and Targets in Autoimmune Disease (#2503-2508) .....109 Networking Break ...........................................102 ACR/ARHP Combined Abstract Session ACR Meet the Professor Sessions ACR/ARHP Combined Epidemiology Abstract Session (#2509-2514) ..110 Basic Immunology for Clinical Rheumatologists (071) ..............102 Fibromyalgia and Dysautonomia (072) ..........................102 ARHP Sessions Myopathy: Issues in Diagnosis and Treatment (073) ...............102 Myositis: Pathogenesis, Diagnosis and Management ...............110 Rheumatoid Arthritis: Challenging Cases (074) ....................102 Rheumatic Disease Update: Systemic Lupus Erythematosus .........111 Rheumatoid Arthritis: Safety of Novel Therapies (075) .............102 Rheumatoid Arthritis Disease Activity Measures and Quality Indicators: Correct Use and Future Directions ....................111 Systemic Lupus Erythematosus: Central Nervous System (076) ......102 Transition Tools for Patients: Pediatric to Adults ...................111 Systemic Lupus Erythematosus: Difficult to Treat Systemic Lupus Erythematosus (077) ........................................102 ACR Workshop Systemic Lupus Erythematosus: Lupus Nephritis (078) .............102 Joint Injection Techniques (239) ................................111 Temporal Arteritis (079) ......................................102 Vasculitis: Update (080) .......................................102 2012 Program Book 7 TABLE OF CONTENTS ARHP Session The Unintended Consequences of Health Information Obesity: It is a Chronic Disease .................................111 Technology ................................................121 ACR Session ARHP Sessions Diagnostic Assessments in Myopathy ...........................111 An Introduction to Immunology ................................121 MicroRNA and the Rheumatic Diseases ..........................112 Beyond the Basics: A Real Life Example of Multiple Imputation for Missing Data Problems (Research Series) .....................121 Should Ultrasound be Used in Rheumatology Practice? ............112 The Great Masqueraders: Malignancies in Rheumatic Disease .......112 ACR Sessions Biosimilars Development: Food and Drug Administration ACR Concurrent Abstract Sessions Perspective ................................................122 Biology and Pathology of Bone and Joint: Regulation of IgG4-Related Disease – Past Lessons and Future Directions .........122 Bone Cells (#2515-2520) .....................................112 NIAMS-Sponsored Research in Rheumatology: 2012 Highlights ......122 Innate Immunity and Rheumatic Disease (#2521-2526) ............113 Osteoarthritis Therapeutics: Will This be the Decade for Miscellaneous Rheumatic and Inflammatory I (#2527-2532) ........113 Breakthroughs? .............................................122 Osteoarthritis – Clinical Aspects I: Weight, Activity, and Predictive Biomarkers: A Journey to Personalized Health Care .......123 Metabolic Effects on Osteoarthritis (#2533-2538) .................114 Rheumatoid Arthritis – Clinical Aspects V: Comorbidities in ACR Concurrent Abstract Sessions Rheumatoid Arthritis (#2539-2544) ............................115 B-cell Biology and Targets in Autoimmune Disease (#2575-2580) ....123 Rheumatoid Arthritis Treatment – Small Molecules, Biologics Imaging of Rheumatic Diseases III: Computed Tomography and Gene Therapy: Efficacy of Approved Biologics (#2545-2550) ....115 (#2581-2586) ...............................................123 Sjögren’s Syndrome II – Clinical (#2551-2556) ....................116 Medical Education (#2587-2592) ...............................124 Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects Pediatric Rheumatology: Clinical and Therapeutic Disease IV: and Treatment: Psoriatic Arthritis (#2557-2562) ..................117 Childhood Therapeutics and Response (#2593-2598) ..............124 Vasculitis: Clinical Aspects (#2563-2568) .........................118 Quality Measures and Innovations in Practice Management and Care Delivery (#2599-2604) ...............................125 ACR Meet the Professor Sessions Rheumatoid Arthritis – Clinical Aspects VI: Remission and Flare Central Nervous System Vasculitis (081) .........................119 in Rheumatoid Arthritis (#2605-2610) ..........................126 Crystal: Pseudogout (082) .....................................119 Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects Effective Use of Technology (083). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 and Treatment: Psoriatic Arthritis and Spondylarthritis Pulmonary Manifestations of Rheumatic Disease (084) .............119 (#2611-2616) ...............................................126 Raynaud’s and Digital Ischemia (085) ............................119 Systemic Lupus Erythematosus – Clinical Aspects and Treatment IV: Rheumatoid Arthritis: Safety of Novel Therapies (086) .............119 Therapeutics (#2617-2622) ...................................127 Rheumatology Practice 101: Starting Out in Practice for ARHP Sessions The Graduating Fellow (087) ..................................119 Forming An Education and Support Group from the Ground Up .....128 Systemic Lupus Erythematosus: Lupus Nephritis (088) .............119 Osteoporosis: 2012 Update ...................................128 Systemic Lupus Erythematosus: Novel Treatments (089) ............119 ARHP Concurrent Abstract Sessions Vaccinations for Patients on Biologic Therapies (090) ..............119 Systemic Sclerosis, Vasculitis, Crohn’s and Spondylarthropathies Rheumatology Research Foundation Special Session (#2623-2628) ...............................................128 Edmond L. Dubois, MD Memorial Lectureship: Clinical and Rehabilitative Aspects of Osteoarthritis (#2629-2634) ...129 Hydroxychloriquine Reduces Thrombosis in Systemic Lupus Erythematosis Particulerly in Antiphospholipid Positive Patients ACR Sessions (#2569-2574) ...............................................119 Amyloidosis 2012 ............................................129 Mechanisms of Autoinflammatory Diseases ......................129 ARHP Sessions Arthritis and the Older Worker .................................120 ACR Sessions Best Practices for Ordering Diagnostic Imaging in Evaluating Making Sense of Autoantibodies in the Diagnosis of Systemic Rheumatologic Conditions ....................................120 Rheumatic Diseases .........................................129 The Puzzle of Fatigue in Rheumatoid Arthritis: Putting the Rheumatoid Arthritis – Treating to Target: How to Incorporate Pieces Together .............................................120 Rheumatoid Arthritis Disease Activity Measures into Routine Practice ...................................................130 Wednesday, November 14, 2012 ACR Concurrent Abstract Sessions ACR Sessions Epidemiology and Health Services Research V: Rheumatoid Immunology of Pregnancy and Impact on Autoimmune Arthritis Management in the Treat-to-Target Era (#2635-2640) ......130 Pathogenesis ...............................................121 Fibromyalgia and Soft Tissue Disorders II (#2641-2646) .............130 Neutrophil Extracellular Traps (NETosis) in Rheumatic Disease .......121 Orthopedics, Low Back Pain, and Rehabilitation (#2647-2652) .......131 Rheumatology Roundup: Highlights from the 2012 Annual Pediatric Rheumatology – Pathogenesis and Genetics Scientific Meeting ...........................................121 (#2653-2658) ...............................................131 8 2012 Program Book

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Concourse (near entrance to Hall A). Coat/Baggage . outline new technologies for the treatment of rheumatologic problems. • describe potential
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